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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 121 - 130 of 133 in total
Gene ID Gene Symbol Description Source
9415 FADS2 fatty acid desaturase 2
9451 EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3
11213 IRAK3 interleukin 1 receptor associated kinase 3
23274 CLEC16A C-type lectin domain containing 16A
29843 SENP1 SUMO specific peptidase 1
51083 GAL galanin and GMAP prepropeptide
54658 UGT1A1 UDP glucuronosyltransferase family 1 member A1
55937 APOM apolipoprotein M
57818 G6PC2 glucose-6-phosphatase catalytic subunit 2
64131 XYLT1 xylosyltransferase 1
Displaying entries 1 - 10 of 102 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11423 Ache acetylcholinesterase
11450 Adipoq adiponectin, C1Q and collagen domain containing
11554 Adrb1 adrenergic receptor, beta 1
11596 Ager advanced glycosylation end product-specific receptor
11669 Aldh2 aldehyde dehydrogenase 2, mitochondrial
11754 Aoc3 amine oxidase, copper containing 3
11814 Apoc3 apolipoprotein C-III
11998 Avp arginine vasopressin
12038 Bche butyrylcholinesterase
Displaying entries 11 - 20 of 61 in total
Gene ID Gene Symbol Description Source
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24586 Ncam1 neural cell adhesion molecule 1
24714 Reg1a regenerating family member 1 alpha
24770 Ccl2 C-C motif chemokine ligand 2
24787 Sod2 superoxide dismutase 2
24825 Tf transferrin
24835 Tnf tumor necrosis factor
24861 Ugt1a1 UDP glucuronosyltransferase family 1 member A1
24925 Adrb1 adrenoceptor beta 1
Displaying entries 31 - 40 of 43 in total
Gene ID Gene Symbol Description Source
43222 Tl Toll
43223 Lerp lysosomal enzyme receptor protein
44058 Ugt36A1 UDP-glycosyltransferase family 36 member A1
53501 Ugt304A1 UDP-glycosyltransferase family 304 member A1
53502 Ugt302K1 UDP-glycosyltransferase family 302 member K1
53503 Ugt303A1 UDP-glycosyltransferase family 303 member A1
53506 Ugt35E2 UDP-glycosyltransferase family 35 member E2
53507 Ugt35C1 UDP-glycosyltransferase family 35 member C1
53511 Ugt37D1 UDP-glycosyltransferase family 37 member D1
53512 Ugt37E1 UDP-glycosyltransferase family 37 member E1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175591 ugt-62 UDP-glucuronosyltransferase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177044 smf-3 NRAMP-like transporter smf-3
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024