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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 61 - 70 of 133 in total
Gene ID Gene Symbol Description Source
3552 IL1A interleukin 1 alpha
3554 IL1R1 interleukin 1 receptor type 1
3557 IL1RN interleukin 1 receptor antagonist
3558 IL2 interleukin 2
3559 IL2RA interleukin 2 receptor subunit alpha
3565 IL4 interleukin 4
3569 IL6 interleukin 6
3586 IL10 interleukin 10
3600 IL15 interleukin 15
3630 INS insulin
Displaying entries 81 - 90 of 102 in total
Gene ID Gene Symbol Description Source
21857 Timp1 tissue inhibitor of metalloproteinase 1
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
21939 Cd40 CD40 antigen
21947 Cd40lg CD40 ligand
22035 Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10
22041 Trf transferrin
22164 Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4
22329 Vcam1 vascular cell adhesion molecule 1
22371 Vwf Von Willebrand factor
Displaying entries 41 - 50 of 61 in total
Gene ID Gene Symbol Description Source
29539 Aldh2 aldehyde dehydrogenase 2 family member
29702 Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3
29714 Ptprn2 protein tyrosine phosphatase, receptor type N2
54225 Apob apolipoprotein B
59086 Tgfb1 transforming growth factor, beta 1
60350 Cd14 CD14 molecule
60582 Il1rn interleukin 1 receptor antagonist
64133 Xylt1 xylosyltransferase 1
83817 Ache acetylcholinesterase
84024 Pon1 paraoxonase 1
Displaying entries 1 - 10 of 43 in total
Gene ID Gene Symbol Description Source
31364 Fas2 Fasciclin 2
31926 Idgf4 Imaginal disc growth factor 4
32974 Zw Zwischenferment
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
35105 Ugt301D1 UDP-glycosyltransferase family 301 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
114549 ache acetylcholinesterase (Yt blood group)
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
447803 pon1 paraoxonase 1
560951 xylt1 xylosyltransferase I
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying entries 1 - 10 of 12 in total
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 29 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175591 ugt-62 UDP-glucuronosyltransferase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177044 smf-3 NRAMP-like transporter smf-3
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024