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Sialyltransferase

Summary

Gene Symbol

SiaT

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

37950

PubChem

37950

Alliance of Genome Resources

FB:FBgn0035050

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9GU23
Q9W121

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein glycosylation	IMP	36946697
protein glycosylation	IEA
neuromuscular junction development	IMP	20445073
oligosaccharide metabolic process	IDA	14612445
sialylation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

sialylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization [inference]

neuromuscular junction development

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular region	IDA	14612445
Golgi apparatus	IDA	14612445
Golgi apparatus	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
beta-galactoside alpha-2,6-sialyltransferase activity	IDA	14612445
beta-galactoside alpha-2,6-sialyltransferase activity	IBA
sialyltransferase activity	IDA	14612445
sialyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

beta-galactoside alpha-2,6-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta-galactoside alpha-2,6-sialyltransferase

Functional Category

H: Coenzyme transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
beta-galactoside alpha-2,6-sialyltransferase activity
sialylation
sialyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
GT29-like superfamiliy
Glycosyl transferase family 29

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
Golgi apparatus	PMID:14612445
extracellular region	PMID:14612445

Rhea

RHEA:21552

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP

Enzyme

2.4.3.1

PMID

2460092

RHEA:52104

a β-D-galactoside + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H⁺ + CMP

Enzyme

2.4.3.1

PMID

RHEA:11836

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP

Enzyme

2.4.3.1

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP008847
Gene Name: Sialyltransferase

Ortholog

Displaying entries **1 - 10** of 18 in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	523	Xenbase:XB-GENE-990439
Xenopus tropicalis	6480	Xenbase:XB-GENE-983202
Xenopus tropicalis	11964	Xenbase:XB-GENE-990439
Xenopus tropicalis	20440	Xenbase:XB-GENE-983202
Xenopus tropicalis	25197	Xenbase:XB-GENE-983202
Xenopus tropicalis	37950	Xenbase:XB-GENE-990439
Xenopus tropicalis	84620	Xenbase:XB-GENE-990439
Xenopus tropicalis	240119	Xenbase:XB-GENE-990439
Xenopus tropicalis	301155	Xenbase:XB-GENE-990439
Xenopus tropicalis	403116	Xenbase:XB-GENE-990439

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements