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MIRAGE
keratin 2
Summary
- Gene Symbol
-
- KRT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Coiled coil
- Cytoplasm
- Disease variant
- Ichthyosis
- Intermediate filament
- Keratin
- Methylation
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P35908 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| keratinocyte activation | ||
| keratinocyte proliferation | ||
| intermediate filament organization | ||
| positive regulation of epidermis development | ||
| keratinocyte migration |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| structural constituent of cytoskeleton | ||
| protein binding | ||
| cytoskeletal protein binding | ||
| structural constituent of skin epidermis | ||
| structural constituent of skin epidermis |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Keratin
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| intermediate filament organization |
| keratinization |
| structural constituent of skin epidermis |
| InterPro |
|---|
| Intermediate filament protein, conserved site |
| Intermediate filament, rod domain |
| Keratin type II head |
| Keratin, type II |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060877 | bullous congenital ichthyosiform erythroderma | |
| DOID:1697 | ichthyosis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3848 | Xenbase:XB-GENE-876590 | ||
| 3849 | Xenbase:XB-GENE-876590 | ||
| 3852 | Xenbase:XB-GENE-6035591 | ||
| 3855 | ZFIN:ZDB-GENE-991110-23 | ||
| 3856 | ZFIN:ZDB-GENE-991110-23 | ||
| 3858 | WB:WBGene00002056 | ||
| 9119 | Xenbase:XB-GENE-6035591 | ||
| 13346 | WB:WBGene00002055 | ||
| 14580 | WB:WBGene00002055 | ||
| 16678 | Xenbase:XB-GENE-6035591 |
