GlyCosmos Portal

Rattus norvegicus (Norway rat)

Summary

Taxonomy ID: 10116
PubChem Taxonomy: 10116

Genes (449) Glycans (773) Glycoproteins (2935) Lectins (166) Pathways (1070)

Displaying entries **501 - 525** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 N-acetylglutamate synthase Ornithine transcarbamylase, mitochondrial Solute carrier family 25 member 2	A0A0G2K309 A0A8I6G8E8 D4A904 O08701 P00481 P07756 P07824 P20673	Arg1 Arg2 Asl Cps1 Nags Otc Slc25a15 Slc25a2
Neurexins and neuroligins	Band 4.1-like protein 1 Band 4.1-like protein 5 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Disks large-associated protein 1 Disks large-associated protein 2 Disks large-associated protein 3 Disks large-associated protein 4 Erythrocyte membrane protein band 4.1-like 2 Homer protein homolog 1 Homer protein homolog 2 Homer protein homolog 3 Leucine-rich repeat transmembrane neuronal protein 1 Leucine-rich repeat transmembrane neuronal protein 2 Leucine-rich repeat transmembrane neuronal protein 3 Leucine-rich repeat transmembrane neuronal protein 4 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 5 Neurexin-1 Neurexin-2 Neurexin-3 Neuroligin-1 Neuroligin-2 Neuroligin-3 Peripheral plasma membrane protein CASK Protein 4.1 SH3 and multiple ankyrin repeat domains protein 1 SH3 and multiple ankyrin repeat domains protein 3 Sorbin and SH3 domain-containing protein 2	A0A0G2K162 A0A8I5Y1T6 B4F7C5 D3ZAL8 D4A6D8 D4A7P2 O35413 O88801 P23385 P31016 P31424 P97836 P97837 P97838 P97839 Q07310 Q5FVG2 Q62765 Q62888 Q62889 Q62915 Q62936 Q63372 Q63374 Q63622 Q9JLU4 Q9WTP0 Q9WV48 Q9Z214 Q9Z2X5	Argbp2 Cask Dap2 Dap3 Dap4 Dlg2 Dlg3 Dlg4 Dlgap1 Dlgap2 Dlgap3 Dlgap4 Dlgh2 Dlgh3 Dlgh4 Epb4.1l1 Epb4.1l5 Epb41 Epb41l1 Epb41l2 Epb41l5 Gkap Gprc1a Gprc1e Grm1 Grm5 Homer Homer1 Homer2 Homer3 Lrrtm1 Lrrtm2 Lrrtm3 Lrrtm4 Mglur1 Mglur5 Nlgn1 Nlgn2 Nlgn3 Nrxn1 Nrxn2 Nrxn3 Prosap2 Psd95 Sapap4 Shank1 Shank3 Sorbs2 Vesl Vesl2 Vesl3
Vitamin D (calciferol) metabolism	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial Cubilin Cytochrome P450, family 2, subfamily r, polypeptide 1 Legumain Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Protein inhibitor of activated STAT, 4 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 2 Vitamin D-binding protein Vitamin D3 receptor	A0A8I6A0G3 B5DFF9 D3ZAR1 O35132 O70244 P04276 P13053 P61959 P63281 P98158 Q09128 Q9R0J8	Arh Cubn Cyp24 Cyp24a1 Cyp27b Cyp27b1 Cyp2r1 Dbp Gc Ifcr Ldlrap1 Lgmn Lrp2 Nr1i1 Pias4 Prsc1 Smt3a Smt3h2 Sumo2 Ubce9 Ube2i Vdr
Sema4D induced cell migration and growth-cone collapse	Plexin B1 Receptor tyrosine-protein kinase erbB-2 Rho family GTPase 1 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB Semaphorin 4D Transforming protein RhoA	A0A0G2K860 A0A8I6G5Q1 D3ZDX5 P06494 P61589 P62747 Q5FVG9 Q62868 Q63644 Q9ES67	Arha Arha2 Arhb Arhgef11 Arhgef12 Erbb2 Neu Plxnb1 Rhoa Rhob Rnd1 Rock1 Rock2 Sema4d
RHO GTPases activate PKNs	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein theta 14-3-3 protein zeta/delta 3-phosphoinositide-dependent protein kinase 1 M-phase inducer phosphatase Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 14A Protein phosphatase 1 regulatory subunit Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Stratifin Transforming protein RhoA	D3ZIC4 D4ADT2 G3V9A3 O08874 O55173 P35213 P61589 P61983 P62142 P62260 P62747 P63102 P68255 P68511 Q10728 Q63433 Q6RUV5 Q99MC0	Arha Arha2 Arhb Cdc25c Cpi Cpi17 Mbs Msfs1 Mypt1 Pak2 Pdk1 Pdpk1 Pkn Pkn1 Pkn2 Ppp1cb Ppp1r12a Ppp1r12b Ppp1r14a Prk1 Prk2 Prkcl1 Prkcl2 Rac Rac1 Rhoa Rhob Sfn Ywhab Ywhae Ywhag Ywhah Ywhaq Ywhaz
GPVI-mediated activation cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3-phosphoinositide-dependent protein kinase 1 C-type lectin domain family 1 member B Cell division control protein 42 homolog Glycoprotein VI High affinity immunoglobulin epsilon receptor subunit gamma Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide-3-kinase, regulatory subunit 6 Podoplanin Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene vav Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5ZPB5 A0A8I6A1P8 A0A8I6G942 A0A8J8YIH6 D3ZFJ0 D3ZJD8 D3ZYG0 D4A4I3 M0R8A3 O55173 O70601 P20411 P24135 P41499 P54100 P61589 P62747 P81718 Q01621 Q07014 Q32PX6 Q62844 Q63787 Q63788 Q63789 Q64294 Q64725 Q6MG59 Q6RUV5 Q8CFN2 Q9Z1L0	Arha Arha2 Arhb Cdc42 Clec1b Fce1g Fcer1g Fyn G6b Gp6 Lat Lck Lcp2 Lyn Mpig6b Pdk1 Pdpk1 Pdpn Pik3ca Pik3cb Pik3cg Pik3r1 Pik3r2 Pik3r3 Pik3r5 Pik3r6 Plcg2 Ptph6 Ptpn11 Ptpn6 Rac Rac1 Rac2 Rhoa Rhob Rhog Syk Vav Vav1 Vav2 Vav3
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Engulfment and cell motility 1 Engulfment and cell motility 2 GTPase HRas GTPase KRas GTPase NRas Paxillin Ras GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Transforming protein RhoA Tyrosine-protein kinase	D3ZDS3 D3ZY46 G3V982 P08644 P20171 P50904 P61589 P81128 Q04970 Q63767 Q63768 Q66H76 Q6RUV5	Arha Arha2 Arhgap35 Bcar1 Cas Crk Crkas Crko Elmo1 Elmo2 Grlf1 Hras Hras1 Kras Kras2 Nras P190A Ptk6 Pxn Rac Rac1 Rasa Rasa1 Rhoa p190ARHOGAP
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin B1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein R-Ras Rho GTPase-activating protein 35 Rho family GTPase 1 Semaphorin 4D Transforming protein RhoA	A0A8I6G5Q1 D3Z8L7 D3ZDX5 P61589 P81128 P97523 Q5FVG9 Q6RUV5	Arha Arha2 Arhgap35 Grlf1 Met P190A Plxnb1 Rac Rac1 Rhoa Rnd1 Rras Sema4d p190ARHOGAP
Axonal growth inhibition (RHOA activation)	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 MCF.2 cell line derived transforming sequence Myelin-associated glycoprotein Oligodendrocyte-myelin glycoprotein Reticulon-4 Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	A0A8I6A9Q4 F7EYB9 G3V881 P07174 P07722 P61589 Q5XI73 Q9JK11	Arha Arha2 Arhgdia Lingo1 Mag Mcf2 Ngfr Nogo Omg Rhoa Rtn4 Tnfrsf16
Axonal growth stimulation	Beta-nerve growth factor Rho GDP-dissociation inhibitor 1 Transforming protein RhoA Tumor necrosis factor receptor superfamily member 16	P07174 P25427 P61589 Q5XI73	Arha Arha2 Arhgdia Ngf Ngfb Ngfr Rhoa Tnfrsf16
ERBB2 Regulates Cell Motility	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Protein MEMO1 Protein diaphanous homolog 1 Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Transforming protein RhoA	A0A8I5Y1H8 A0A8I6AQ55 F1M775 G3V6K6 O35569 P06494 P07522 P43322 P61589 Q06175 Q4QQR9 Q62799 Q9Z0L5	Arha Arha2 Btc Diap1 Diaph1 Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Memo1 Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Rhoa
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Polyubiquitin-B Polyubiquitin-C Protein kinase C zeta type TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2K612 A0A8I6A4L9 A0A8I6A5Y3 P09217 P0CG51 P17246 P38438 P61589 P62982 P80204 Q63429 Q6B4M5 Q9JHY1 Q9Z340	Arha Arha2 Cgn F11r Jam1 LOC100360645 Par-6a Par3 Par6a Pard3 Pard6a Pkcz Prkcz Rhoa Rps27a Smurf1 Tgfb1 Tgfbr1 Tgfbr2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1
PCP/CE pathway	Dishevelled associated activator of morphogenesis 1 Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 Frizzled class receptor 3 Frizzled class receptor 7 Frizzled-1 Frizzled-6 Profilin-1 Protein Wnt-4 Protein Wnt-5a Protein Wnt Protein Wnt Protein Wnt Rac family small GTPase 2 Ras-related C3 botulinum toxin substrate 1 Segment polarity protein dishevelled homolog DVL-1 Transforming protein RhoA	A0A8I6A1P8 A0A8I6GKX7 A0A8I6GM04 B1WBR9 D3ZB71 D4A9J2 D4ACM8 G3V6L1 G3V819 M0RCN5 P61589 P62963 Q08463 Q6RUV5 Q9QXQ5 Q9QXQ7 Q9WVB9	Arha Arha2 Daam1 Dvl1 Dvl2 Dvl3 Fzd1 Fzd3 Fzd6 Fzd7 LOC100361515 Pfn1 Rac Rac1 Rac2 Rhoa Wnt-4 Wnt-5a Wnt1 Wnt11 Wnt4 Wnt5a Wnt5b
PI3K/AKT activation	Beta-nerve growth factor High affinity nerve growth factor receptor Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Transforming protein RhoA	A0A0G2K344 F1MAL5 P25427 P35570 P35739 P61589 Q63787 Q63788 Q9Z1L0	Arha Arha2 Irs-1 Irs1 Irs2 Ngf Ngfb Ntrk1 Pik3ca Pik3cb Pik3r1 Pik3r2 Rhoa Trk Trka
RHOJ GTPase cycle	DEP domain containing 1B Dedicator of cytokinesis 8 Inositol polyphosphate 5-phosphatase OCRL Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Ras homolog family member J Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein SYDE1 Triple functional domain protein	A0A0G2JYR5 A0A0G2K7N9 A0A8I6A829 A0A8I6APL5 A0A8I6GDA1 A0A8I6GLR6 D3ZGS3 D3ZZN9 D4AA32 F1M0Z1 F1MAK3 P0CAX5 P81128 Q5RJS2 Q63787 Q63788	Arhgap1 Arhgap21 Arhgap26 Arhgap32 Arhgap35 Arhgap5 Depdc1b Dock8 Grlf1 Ocrl Ophn1 P190A Pik3r1 Pik3r2 Prex1 Rhoj Syde1 Trio p190ARHOGAP
RHOV GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Cell division control protein 42 homolog Centriolar coiled-coil protein 110 Centrosomal protein 97 Clathrin heavy chain 1 Cytoplasmic protein Cytoplasmic protein DEP domain containing 1B Discs large MAGUK scaffold protein 5 Dystonin E3 ubiquitin-protein ligase SH3RF1 IQ motif containing GTPase activating protein 1 Mitogen-activated protein kinase kinase kinase 11 Par-6 family cell polarity regulator beta Partitioning defective 6 homolog alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Pseudopodium-enriched atypical kinase 1 Rho GTPase activating protein 12 Rho guanine nucleotide exchange factor 7 Rho-related GTP-binding protein RhoV Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain Thioredoxin-like protein 1 Tropomyosin alpha-4 chain Unconventional myosin-IXa Vang-like protein Zinc finger protein 512B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A8I5ZQD4 A0A8I6AJD9 A0A8I6AN18 A0A8I6GLX4 B2RZ33 B5DF62 D3ZBN3 D3ZKC8 D3ZQ51 D4A2F2 D4A3J9 D4A3M8 D4A563 D4AA32 D4AC95 G3V6S0 G3V7Q7 O55043 P09495 P11442 P16086 P35465 Q5XFW6 Q63787 Q64303 Q66H91 Q66HA1 Q6B4M5 Q71F54 Q8CFN2 Q920J4 Q9Z1N3 Q9Z1Y0 Q9Z272	Arhgap12 Arhgef7 Ccp110 Cdc42 Cep97 Cltc Depdc1b Dlg5 Dst Epha2 Git1 Git2 Iqgap1 Map3k11 Mlk3 Myo9a Myr7 Nck1 Nck2 Pak1 Pak2 Pak3bp Pak4 Pak6 Par-6a Par6a Pard6a Pard6b Peak1 Pik3r1 Pixb Posh Posh1 RGD1312026 Rhov Sh3md2 Sh3rf1 Spna2 Spta2 Sptan1 Sptbn1 Tpm4 Trp Txnl1 Vangl1 Wdr6 Zfp512b
RHOU GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Cell division control protein 42 homolog Clathrin heavy chain 1 Cytoplasmic protein Cytoplasmic protein DEP domain containing 1B Discs large MAGUK scaffold protein 5 Dystonin E3 ubiquitin-protein ligase Growth factor receptor-bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate IQ motif containing GTPase activating protein 1 Intersectin 2 Partitioning defective 6 homolog alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein-tyrosine kinase 2-beta Pseudopodium-enriched atypical kinase 1 Ras homolog family member U Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 SLIT-ROBO Rho GTPase-activating protein 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Signal transducing adapter molecule 2 Signal transducing adaptor molecule Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain Thioredoxin-like protein 1 Unconventional myosin-VI Vang-like protein non-specific serine/threonine protein kinase receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A8I5ZQD4 A0A8I6A8K6 A0A8I6ACM8 A0A8I6AMY1 A0A8I6GLX4 B2RZ33 B4F767 B5DF55 B5DF62 D3ZBN3 D3ZCI3 D3ZKC8 D4A208 D4A3M8 D4A563 D4A987 D4AA32 G3V6S0 G3V7Q7 O55043 P11442 P16086 P35465 P62994 P70600 Q5XFW6 Q5XHY7 Q5XXR3 Q62829 Q63787 Q63788 Q64303 Q66H91 Q6B4M5 Q8CFN2 Q920J4 Q9JJ50 Q9Z272	Arhgap30 Arhgap31 Arhgef6 Arhgef7 Ash Cdc42 Cltc Depdc1b Dlg5 Dst Epha2 Fak2 Git1 Git2 Grb2 Hgs Hrs Hrs2 Iqgap1 Itsn2 Myo6 Nck1 Nck2 Pak1 Pak2 Pak3 Pak3bp Pak4 Par-6a Par6a Pard6a Peak1 Pik3r1 Pik3r2 Pixb Ptk2b Pyk2 RGD1312026 Rhou Spna2 Spta2 Sptan1 Sptbn1 Srgap2 Stam Stam2 Trp Txnl1 Vangl1 Wdr6 Wwp2
RHOH GTPase cycle	Caveolin-1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Fam91a1 protein Glioblastoma amplified sequence Junction plakoglobin Methionine synthase NSFL1 cofactor p47 Neutral amino acid transporter B(0) Proto-oncogene tyrosine-protein kinase LCK Ragulator complex protein LAMTOR1 Ral GTPase-activating protein subunit alpha-1 Ras homolog family member H Ras-related protein Rab-7a Rho GDP dissociation inhibitor beta Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 5 Sodium bicarbonate cotransporter 3 Stomatin Transferrin receptor protein 1 Transitional endoplasmic reticulum ATPase Transmembrane protein 59 Tubulin alpha-1B chain Tyrosine-protein kinase CSK Tyrosine-protein kinase Uveal autoantigen with coiled-coil domains and ankyrin repeats Vang-like protein Vesicle-associated membrane protein 3 WD repeat domain 11 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A8I5ZRJ5 A0A8I5ZV26 A0A8I5ZXI2 A0A8I6AHV6 B2GV15 B2RYP3 B5DF62 D3Z9L5 D3ZGS5 D3ZJ25 D3ZKC8 D3ZQ51 D3ZTP3 D4A280 O35987 O55007 P09527 P32577 P35465 P41350 P46462 P63025 Q01621 Q5BJZ5 Q5RK08 Q5XI73 Q62868 Q63644 Q64303 Q6P0K8 Q6P791 Q6P9V9 Q99376 Q9R1N3 Q9Z2Q4	Arhgdia Arhgdib Arhgdig Cav Cav1 Csk Dbt Fam91a1 Garnl1 Gbas Jup LOC498174 Lamtor1 Lck Mtr Nbc Nbc2 Nbc3 Nbcn1 Nipsnap2 Nsfl1c Pak1 Pak2 Pak4 Pak5 Pak6 Pak7 Pg RGD1310313 Rab7 Rab7a Ralgapa1 Rhoh Rock1 Rock2 Slc1a5 Slc4a7 Stom Syb3 Tfrc Tmem59 Trfr Tuba1b Tuba2 Tulip1 Uaca Vamp3 Vangl1 Vcp Wdr11 Zap70
G beta:gamma signalling through CDC42	Cell division control protein 42 homolog Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Rho guanine nucleotide exchange factor 6 Serine/threonine-protein kinase PAK 1	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 P35465 P43425 P52287 P54311 P54313 P61954 P62882 P63077 P63219 Q5XXR3 Q8CFN2	Arhgef6 Cdc42 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Pak1
Ephrin signaling	ARF GTPase-activating protein GIT1 Cytoplasmic protein Ephrin B3 Ephrin type-B receptor 1 Ephrin type-B receptor 3 Ephrin type-B receptor 6 Ephrin-B1 Myosin regulatory light chain RLC-A Proto-oncogene tyrosine-protein kinase Src Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor 7 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Syntenin-1 Tyrosine-protein kinase Fyn receptor protein-tyrosine kinase receptor protein-tyrosine kinase	D3ZH39 D4A3M8 F1MAJ0 G3V7D4 M0RDA4 O55043 P09759 P0C0K7 P13832 P35465 P52796 Q62829 Q62844 Q64303 Q6RUV5 Q9JI92 Q9WUD9 Q9Z272	Arhgef7 Efnb1 Efnb3 Elk Ephb1 Ephb2 Ephb3 Ephb4 Ephb6 Eplg2 Epth2 Fyn Git1 LOC686310 Lerk2 Nck2 Pak1 Pak2 Pak3 Pak3bp Pixb Rac Rac1 Rlc-a Sdcbp Src
GABA receptor activation	Gamma-aminobutyric acid receptor subunit alpha-1 Gamma-aminobutyric acid receptor subunit alpha-2 Gamma-aminobutyric acid receptor subunit alpha-3 Gamma-aminobutyric acid receptor subunit alpha-4 Gamma-aminobutyric acid receptor subunit alpha-5 Gamma-aminobutyric acid receptor subunit alpha-6 Gamma-aminobutyric acid receptor subunit beta-1 Gamma-aminobutyric acid receptor subunit beta-2 Gamma-aminobutyric acid receptor subunit beta-3 Gamma-aminobutyric acid receptor subunit gamma-2 Gamma-aminobutyric acid receptor subunit gamma-3 Gamma-aminobutyric acid receptor subunit rho-1 Gamma-aminobutyric acid receptor subunit rho-2 Gamma-aminobutyric acid receptor subunit rho-3 Gamma-aminobutyric acid type A receptor subunit theta Rho guanine nucleotide exchange factor 9	G3V875 P15431 P18508 P19969 P20236 P23576 P28471 P28473 P30191 P47742 P50572 P50573 P62813 P63079 P63138 Q9QX73	Arhgef9 Gabra-1 Gabra-2 Gabra-3 Gabra-5 Gabra-6 Gabra1 Gabra2 Gabra3 Gabra4 Gabra5 Gabra6 Gabrb-1 Gabrb-2 Gabrb-3 Gabrb1 Gabrb2 Gabrb3 Gabrg2 Gabrg3 Gabrq Gabrr1 Gabrr2 Gabrr3
HDMs demethylate histones	AT-rich interactive domain-containing protein 5B Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Histone H3.1 Histone H3 Histone H4 Lysine demethylase 1B Lysine demethylase 2A Lysine demethylase 7A Lysine-specific demethylase 3A Lysine-specific demethylase 4D Lysine-specific demethylase Lysine-specific histone demethylase PHD finger protein 2 PHD finger protein 8 Ribosomal oxygenase 2 [histone H3]-dimethyl-L-lysine(36) demethylase [histone H3]-trimethyl-L-lysine(27) demethylase [histone H3]-trimethyl-L-lysine(27) demethylase [histone H3]-trimethyl-L-lysine(27) demethylase [histone H3]-trimethyl-L-lysine(4) demethylase [histone H3]-trimethyl-L-lysine(4) demethylase [histone H3]-trimethyl-L-lysine(4) demethylase [histone H3]-trimethyl-L-lysine(4) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase	A0A0G2K1H0 A0A0G2K1Z1 A0A0G2K3N6 A0A0G2K5I7 A0A0G2K6V2 A0A0G2K736 A0A8I5ZPK6 A0A8I5ZVJ1 A0A8I5ZXX2 A0A8I6A5T3 A0A8I6ABR9 A0A8I6AEL5 A0A8I6AFH2 A0A8I6GMK8 A1A5Q5 D3ZJ08 D3ZP89 D3ZTJ7 D4AD31 F1LS62 M0RB75 P62804 Q63679 Q6AYK2 Q6LED0 Q8CFC1	Arid5b H3c13 H4c16 H4c2 H4f16 H4ft Hist1h4b Hist1h4m Hist2h3c2 Hist4 Hist4h4 Jhdm2a Jhdm3d Jmjd1a Jmjd2d Jmjd6 Kdm1a Kdm1b Kdm2a Kdm2b Kdm3a Kdm3b Kdm4a Kdm4b Kdm4c Kdm4d Kdm5a Kdm5b Kdm5c Kdm5d Kdm6a Kdm6b Kdm7a Mina Mina53 Phf2 Phf8 Ptdsr Riox2 Tsga Uty
ISG15 antiviral mechanism	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beclin-1 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase NEDD4 Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic initiation factor 4A-III Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4 gamma 2 Eukaryotic translation initiation factor 4 gamma, 3 Eukaryotic translation initiation factor 4E Filamin B ISG15 ubiquitin-like modifier Interferon regulatory factor 3 Interferon-induced GTP-binding protein Mx2 Interferon-induced protein with tetratricopeptide repeats 1B-like Interferon-induced, double-stranded RNA-activated protein kinase Mitogen-activated protein kinase 3 Protein phosphatase 1B RBR-type E3 ubiquitin transferase RNA helicase Signal transducer and activator of transcription 4 Tripartite motif-containing 25 Tyrosine-protein kinase Ubiquitin-like modifier activating enzyme 7 Ubiquitin/ISG15-conjugating enzyme E2 L6 ubiquitinyl hydrolase 1	A0A0G2JX93 A0A0G2JXT8 A0A0G2K735 A0A8I6A1T4 A0A8I6AM23 A0A8I6AMY8 A0A8I6APR1 D3ZXL1 D4A3X3 D4A9N5 D4ADT5 F1M3L4 F7EXX5 F7F7A6 M0RD03 P10686 P18589 P21708 P35815 P63074 Q3B8Q2 Q4V8J2 Q5RKI1 Q62940 Q63184 Q6AYC7 Q91XJ1	Arih1 Becn1 Ddx48 Eif2ak2 Eif4a1 Eif4a2 Eif4a3 Eif4e Eif4g1 Eif4g2 Eif4g3 Erk1 Flnb Ifit1bl Irf3 Isg15 Jak1 LOC100366017 Mapk3 Mx2 Nedd4 Nedd4a Plcg1 Pp2c2 Ppm1b Pppm1b Prkm3 Prkr Rig1 Rpf1 Stat1 Stat4 Trim25 Uba7 Ube2e1 Ube2l6 Usp18
BBSome-mediated cargo-targeting to cilium	ADP-ribosylation factor-like protein 6 Bardet-Biedl syndrome 1 Bardet-Biedl syndrome 2 protein homolog Bardet-Biedl syndrome 4 Bardet-Biedl syndrome 7 protein homolog Bardet-Biedl syndrome 9 Leucine zipper transcription factor-like protein 1 Melanin-concentrating hormone receptor 1 Protein smoothened Rab-3A-interacting protein Somatostatin receptor type 3 Tetratricopeptide repeat domain 8	A0A1P8YVD0 A0A8I6AHB5 A0A8I6GF94 D4A4U2 F1M285 P30936 P97639 P97698 Q562C6 Q62739 Q66H90 Q99MH9	Arl6 Bbs1 Bbs2 Bbs4 Bbs7 Bbs9 Gpr24 Lztfl1 Mchr1 Rab3ip Rabin3 Rabin8 Slc1 Smo Smoh Sstr3 Ttc8
Glutamate Neurotransmitter Release Cycle	Amino acid transporter Complexin-1 Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 Glutaminase kidney isoform, mitochondrial Glutaminase liver isoform, mitochondrial Liprin-alpha-3 Liprin-alpha-4 (Fragment) PRA1 family protein 3 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Sodium-coupled neutral amino acid symporter 2 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular glutamate transporter 1	A0A1B0GWS0 A0A8I6AK94 D3ZT83 O35921 P13264 P21707 P24942 P28492 P31596 P32851 P51907 P60881 P61765 P63012 P63041 P63045 Q62634 Q62769 Q91Z79 Q91Z80 Q9ES40 Q9JHE5 Q9JIR0 Q9JIR4	Arl6ip5 Ata2 Bnpi Bzrap1 Cplx1 Eaac1 Eaat1 Eaat2 Eaat3 Eaat4 Ga Gls Gls2 Glt1 Gtrap3-18 Jwa Ppfia1 Ppfia2 Ppfia3 Ppfia4 Pra2 Praf3 Rab3a Rbp1 Rim1 Rims1 Sa1 Sap Sat2 Slc17a7 Slc1a1 Slc1a2 Slc1a3 Slc1a6 Slc1a7 Slc38a2 Snap Snap25 Snat2 Stx1a Stxbp1 Syb2 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vamp2 Vglut1

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