GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **2001 - 2025** of **2090** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
Regulation of PAK-2p34 activity by PS-GAP/RHG10	Rho GTPase-activating protein 10 Serine/threonine-protein kinase PAK 2	A1A4S6 Q13177	ARHGAP10 GRAF2 PAK2	Homo sapiens (human)
RPIA deficiency: failed conversion of R5P to RU5P	Ribose-5-phosphate isomerase	P49247	RPI RPIA	Homo sapiens (human)
RPIA deficiency: failed conversion of RU5P to R5P	Ribose-5-phosphate isomerase	P49247	RPI RPIA	Homo sapiens (human)
PRPP biosynthesis	Ribose-phosphate pyrophosphokinase 1 Ribose-phosphate pyrophosphokinase 2 Ribose-phosphate pyrophosphokinase 3	P11908 P21108 P60891	PRPS1 PRPS1L1 PRPS2 PRPS3 PRPSL	Homo sapiens (human)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Ribosomal protein S6 kinase alpha-6	P51812 Q15349 Q15418 Q9UK32	ISPK1 MAPKAPK1A MAPKAPK1B MAPKAPK1C RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 RSK1 RSK2 RSK3 RSK4	Homo sapiens (human)
SLIT2:ROBO1 increases RHOA activity	Roundabout homolog 1 Slit homolog 2 protein Transforming protein RhoA Unconventional myosin-IXb	O94813 P61586 Q13459 Q9Y6N7	ARH12 ARHA DUTT1 MYO9B MYR5 RHO12 RHOA ROBO1 SLIL3 SLIT2	Homo sapiens (human)
Synthesis of wybutosine at G37 of tRNA(Phe)	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 tRNA (guanine(37)-N1)-methyltransferase tRNA wybutosine-synthesizing protein 2 homolog tRNA wybutosine-synthesizing protein 3 homolog tRNA wybutosine-synthesizing protein 4 tRNA wybutosine-synthesizing protein 5	A2RUC4 O60294 Q32P41 Q53H54 Q6IPR3 Q9NV66	C1orf171 C2orf60 KIAA0547 KIAA1393 LCMT2 RSAFD1 TRM12 TRM5 TRMT12 TRMT5 TYW1 TYW2 TYW3 TYW4 TYW5	Homo sapiens (human)
SUMO is conjugated to E1 (UBA2:SAE1)	SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 Q9UBE0 Q9UBT2	AOS1 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBL1 UBLE1A UBLE1B	Homo sapiens (human)
SUMO is proteolytically processed	Sentrin-specific protease 1 Sentrin-specific protease 2 Sentrin-specific protease 5 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 Q96HI0 Q9HC62 Q9P0U3	KIAA1331 SENP1 SENP2 SENP5 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUMO1 SUMO2 SUMO3 UBL1	Homo sapiens (human)
STAT6-mediated induction of chemokines	Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 6 Stimulator of interferon genes protein	P42226 Q86WV6 Q9UHD2	ERIS MITA NAK STAT6 STING STING1 TBK1 TMEM173	Homo sapiens (human)
Integration of energy metabolism	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	P30153 P30154 P62714 P67775 Q14738	PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D	Homo sapiens (human)
Defective SLC17A5 causes Salla disease (SD) and ISSD	Sialin	Q9NRA2	SLC17A5	Homo sapiens (human)
Reuptake of GABA	Sodium- and chloride-dependent GABA transporter 1 Sodium- and chloride-dependent GABA transporter 2 Sodium- and chloride-dependent GABA transporter 3 Sodium- and chloride-dependent betaine transporter	P30531 P48065 P48066 Q9NSD5	BGT1 GABATR GABT1 GABT3 GAT1 GAT2 GAT3 SLC6A1 SLC6A11 SLC6A12 SLC6A13	Homo sapiens (human)
Defective SLC6A5 causes hyperekplexia 3 (HKPX3)	Sodium- and chloride-dependent glycine transporter 2	Q9Y345	GLYT2 NET1 SLC6A5	Homo sapiens (human)
Variant SLC6A14 may confer susceptibility towards obesity	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)	Q9UN76	SLC6A14	Homo sapiens (human)
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	Sodium- and chloride-dependent transporter XTRP3	Q9NP91	SIT1 SLC6A20 XT3 XTRP3	Homo sapiens (human)
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	Sodium- and chloride-dependent transporter XTRP3	Q9NP91	SIT1 SLC6A20 XT3 XTRP3	Homo sapiens (human)
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)	Sodium-dependent dopamine transporter	Q01959	DAT1 SLC6A3	Homo sapiens (human)
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)	Sodium-dependent dopamine transporter	Q01959	DAT1 SLC6A3	Homo sapiens (human)
Defective SLC6A19 causes Hartnup disorder (HND)	Sodium-dependent neutral amino acid transporter B(0)AT1	Q695T7	B0AT1 SLC6A19	Homo sapiens (human)
Defective SLC6A19 causes Hartnup disorder (HND)	Sodium-dependent neutral amino acid transporter B(0)AT1	Q695T7	B0AT1 SLC6A19	Homo sapiens (human)
Defective SLC6A2 causes orthostatic intolerance (OI)	Sodium-dependent noradrenaline transporter	P23975	NAT1 NET1 SLC6A2 SLC6A5	Homo sapiens (human)
Type II Na+/Pi cotransporters	Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Sodium-dependent phosphate transport protein 2C	O95436 Q06495 Q8N130	NPT2 NPT2C NPTIIC SLC17A2 SLC34A1 SLC34A2 SLC34A3	Homo sapiens (human)
Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1)	Sodium-dependent phosphate transport protein 2A	Q06495	NPT2 SLC17A2 SLC34A1	Homo sapiens (human)
Defective SLC34A2 causes PALM	Sodium-dependent phosphate transport protein 2B	O95436	SLC34A2	Homo sapiens (human)

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