GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
PINK1-PRKN Mediated Mitophagy	Autophagy protein 5 E3 ubiquitin-protein ligase parkin Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM22 homolog Mitochondrial import receptor subunit TOM40 homolog Mitochondrial import receptor subunit TOM7 homolog Mitochondrial import receptor subunit TOM70 Mitofusin-1 Mitofusin-2 Polyubiquitin-B Polyubiquitin-C Sequestosome-1 Serine/threonine-protein kinase PINK1, mitochondrial Transcription termination factor 3, mitochondrial Translocase of outer mitochondrial membrane 5 Ubiquitin B-like Ubiquitin-like protein ATG12 Ubiquitin-ribosomal protein eS31 fusion protein Voltage-dependent anion-selective channel protein 1	A0A1B0GWY3 A0A8I6A5Y3 B5DFG1 D3ZMR1 O08623 P0CG51 P62982 Q2TBJ5 Q3MQ06 Q62625 Q62760 Q63429 Q6P6Q6 Q6XVN8 Q75Q39 Q75Q40 Q75Q41 Q8R4Z9 Q8R500 Q9JK66 Q9Z2L0	Apg12l Atg12 Atg5 Fzo1a Fzo1b LOC100360645 Map1alc3 Map1lc3 Map1lc3a Map1lc3b Mfn1 Mfn2 Mterf3 Mterfd1 Park2 Pink1 Prkn Rps27a Sqstm1 Tom22 Tom40 Tom40a Tomm20 Tomm22 Tomm40 Tomm5 Tomm7 Tomm70 Tomm70a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vdac1 Zip	Rattus norvegicus (Norway rat)
BBSome-mediated cargo-targeting to cilium	ADP-ribosylation factor-like protein 6 Bardet-Biedl syndrome 1 Bardet-Biedl syndrome 2 protein homolog Bardet-Biedl syndrome 4 Bardet-Biedl syndrome 7 protein homolog Bardet-Biedl syndrome 9 Leucine zipper transcription factor-like protein 1 Melanin-concentrating hormone receptor 1 Protein smoothened Rab-3A-interacting protein Somatostatin receptor type 3 Tetratricopeptide repeat domain 8	A0A1P8YVD0 A0A8I6AHB5 A0A8I6GF94 D4A4U2 F1M285 P30936 P97639 P97698 Q562C6 Q62739 Q66H90 Q99MH9	Arl6 Bbs1 Bbs2 Bbs4 Bbs7 Bbs9 Gpr24 Lztfl1 Mchr1 Rab3ip Rabin3 Rabin8 Slc1 Smo Smoh Sstr3 Ttc8	Rattus norvegicus (Norway rat)
Multifunctional anion exchangers	Anion exchange transporter Chloride anion exchanger Pendrin Solute carrier family 26 member 11 Solute carrier family 26 member 6 Solute carrier family 26 member 9 Solute carrier family 5 member 12 Sulfate anion transporter 1 Sulfate transporter	A0A1W2Q610 D3Z9I5 D3ZV32 F1LWL8 F1M067 O70531 P45380 Q924C9 Q9R154	Dra Dtdst Pds Sat1 Slc26a1 Slc26a11 Slc26a2 Slc26a3 Slc26a4 Slc26a6 Slc26a7 Slc26a9 Slc5a12	Rattus norvegicus (Norway rat)
The activation of arylsulfatases	Arylsulfatase A Arylsulfatase B Arylsulfatase E Arylsulfatase G Arylsulfatase I Arylsulfatase K Arylsulfatase family, member J Steryl-sulfatase Sulfatase modifying factor 1 Sulfatase modifying factor 2	A0A1W2Q645 D4A7I8 P15589 P50430 Q32KJ2 Q32KJ7 Q32KJ8 Q32KJ9 Q32KK0 Q32KK2	AABR07013255.1 Arsa Arsb Arse Arsg Arsi Arsj Arsk Arsl Sts Sumf1 Sumf2	Rattus norvegicus (Norway rat)
LGI-ADAM interactions	ADAM metallopeptidase domain 11 ADAM metallopeptidase domain 22 ADAM metallopeptidase domain 23 Disks large homolog 4 Leucine-rich glioma-inactivated protein 1 Leucine-rich repeat LGI family, member 2 Leucine-rich repeat LGI family, member 3 Leucine-rich repeat LGI family, member 4 Syntaxin-1A Syntaxin-1B Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-3 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-8 subunit	A0A1W2Q6C2 A0A8I5Y6E8 A0A8I6A4T9 B5DF14 D3ZN61 P31016 P32851 P61265 Q6P2A4 Q71RJ2 Q8K4Y5 Q8VHW5 Q8VHW9 Q8VHX0	Adam11 Adam22 Adam23 Cacng2 Cacng3 Cacng4 Cacng8 Dlg4 Dlgh4 Lgi1 Lgi2 Lgi3 Lgi4 Psd95 Sap Stg Stx1a Stx1b Stx1b2	Rattus norvegicus (Norway rat)
Opsins	Medium-wave-sensitive opsin 1 Melanopsin Opsin 3 Opsin 5 Retinal G protein coupled receptor Retinal pigment epithelium derived rhodopsin homolog Rhodopsin Short-wave-sensitive opsin 1	A0A1W2Q6H2 A0A8J8YD44 D3ZFS1 D3ZG87 O35476 P51489 Q63652 Q8R456	Bcp Gcp Opn1mw Opn1sw Opn3 Opn4 Opn5 Rgr Rho Rrh	Rattus norvegicus (Norway rat)
Maturation of TCA enzymes and regulation of TCA cycle	Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Frataxin, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial Sirtuin 3 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase assembly factor 2, mitochondrial	A0A8I5XWT5 D3ZYW7 P17764 P56574 Q5RJQ7 Q920L2 Q9ER34	Acat1 Aco2 Fxn Idh2 Pgl2 Sdh5 Sdha Sdhaf2 Sirt3	Rattus norvegicus (Norway rat)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 7 Polyubiquitin-B Polyubiquitin-C Prostate transmembrane protein, androgen induced 1 Serine-threonine kinase receptor-associated protein TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A8I5Y0P5 A0A8I6A5Y3 A0A8I6AFY1 M0RCH9 O70436 O88406 P0CG51 P17246 P38438 P62982 P80204 P84025 Q5XIG8 Q63429 Q91XN4	Bambi LOC100360645 Madh2 Madh3 Madh7 Mtmr4 Pmepa1 Rps27a Smad2 Smad3 Smad7 Smurf2 Strap Tgfb1 Tgfbr1 Tgfbr2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Unrip	Rattus norvegicus (Norway rat)
Metabolism of folate and pterines	10-formyltetrahydrofolate dehydrogenase 5-formyltetrahydrofolate cyclo-ligase Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial C-1-tetrahydrofolate synthase, cytoplasmic Cytosolic 10-formyltetrahydrofolate dehydrogenase Dihydrofolate reductase Folate receptor beta Folylpolyglutamate synthase Methylenetetrahydrofolate reductase Proton-coupled folate transporter Reduced folate transporter Serine hydroxymethyltransferase Serine hydroxymethyltransferase Solute carrier family 25 member 32 formate--tetrahydrofolate ligase methenyltetrahydrofolate cyclohydrolase	A0A8I5Y115 A0A8I5ZRH3 A0A8I6A4C5 A0A8I6AG23 A0A8I6GID3 B2GUZ3 D3ZUA0 D4A4S5 M0R401 P27653 P28037 Q5EBA8 Q5U3Z7 Q62866 Q6TXG7 Q920D2	Aldh1l1 Aldh1l2 Dhfr Folr2 Fpgs Fthfd Hcp1 Mthfd Mthfd1 Mthfd1l Mthfd2 Mthfd2l Mthfr Mthfs Pcft Shmt1 Shmt2 Slc19a1 Slc25a32 Slc46a1	Rattus norvegicus (Norway rat)
Negative regulation of MAPK pathway	14-3-3 protein beta/alpha BRCA1 associated protein Dual specificity protein phosphatase 1 Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 5 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Dual specificity protein phosphatase GTPase HRas GTPase KRas GTPase NRas Kinase suppressor of ras 1 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Polyubiquitin-B Polyubiquitin-C Protein phosphatase 2 scaffold subunit A alpha RAF proto-oncogene serine/threonine-protein kinase Serine/threonine-protein kinase A-Raf Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 5 Tyrosine-protein phosphatase non-receptor type 7 Tyrosine-protein phosphatase non-receptor type Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein non-specific serine/threonine protein kinase protein-serine/threonine phosphatase protein-serine/threonine phosphatase protein-serine/threonine phosphatase protein-tyrosine-phosphatase	A0A8I5Y120 A0A8I5ZMG6 A0A8I5ZQW6 A0A8I5ZRC2 A0A8I6A5Y3 A0A8I6A6K6 A0A8I6AJQ7 A0A8I6ATH0 D3ZBG7 D3ZDI7 D3ZNK9 D4A3W6 F1LQQ5 O54838 P08644 P0CG51 P11345 P14056 P20171 P21708 P31044 P35213 P49445 P53042 P62716 P62982 P63086 P63331 Q04970 Q2YDV1 Q4QQT4 Q5XI34 Q62767 Q63340 Q63429 Q63538 Q64346 Q64623 Q80W83 Q8VHF0	A-raf Araf Araf1 Braf Brap Cl100 Dusp1 Dusp10 Dusp16 Dusp4 Dusp5 Dusp6 Dusp7 Dusp8 Dusp9 ENSRNOG00000069024 Erk1 Erk2 Hras Hras1 Kras Kras2 Ksr1 LOC100360645 LOC100909468 Lcptp Mapk Mapk1 Mapk12 Mapk3 Mark3 Mkp1 Mkp2 Mkp3 Mkpx Nras Pbp Pebp Pebp1 Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Ppp5c Prkm1 Prkm3 Ptpn16 Ptpn3 Ptpn7 Raf Raf1 Rps27a Sapk3 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ywhab	Rattus norvegicus (Norway rat)
RAF activation	14-3-3 protein beta/alpha BRCA1 associated protein Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-3 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 GTPase HRas GTPase KRas GTPase NRas Kinase suppressor of ras 1 Leucine-rich repeat protein SHOC-2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase kinase kinase 11 Prohibitin 1 Protein phosphatase 2 scaffold subunit A alpha Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Tyrosine-protein kinase JAK2 non-specific serine/threonine protein kinase	A0A8I5Y120 A0A8I5ZMG6 A0A8I5ZQW6 A0A8I5ZRC2 A0A8I6A6K6 A0A8I6ATH0 D3ZDI7 P08413 P08644 P0DP31 P11275 P11345 P11730 P14056 P15791 P20171 P35213 P36506 P62142 P62716 P63088 P63331 P67779 P97538 Q01986 Q04970 Q4QQT4 Q5XI34 Q62689 Q66HA1 Q6AYI5 Q80W83 Q8VHF0 Q9WUD9	A-raf Araf Araf1 Braf Brap CaMIII Calm3 Cam3 Camc Camk2a Camk2b Camk2d Camk2g Hras Hras1 Jak2 Kras Kras2 Ksr1 LOC100909468 Map2k1 Map2k2 Map3k11 Mark3 Mek1 Mek2 Mkk2 Mlk3 Mras Nras Phb Phb1 Ppp1cb Ppp1cc Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Ppp2r5b Ppp2r5c Ppp2r5d Ppp2r5e Prkmk1 Prkmk2 Raf Raf1 Rras3 Shoc2 Src Ywhab	Rattus norvegicus (Norway rat)
HS-GAG degradation	Agrin Alpha-L-iduronidase Beta-galactosidase-1-like protein 3 Beta-galactosidase Beta-galactosidase Beta-glucuronidase Galactosidase, beta 1-like Glypican 4 Glypican 5 Glypican 6 Glypican-1 Glypican-2 Glypican-3 Heparanase 2 (inactive) Heparanase Iduronate 2-sulfatase N-acetyl-alpha-glucosaminidase N-sulfoglucosamine sulfohydrolase Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4	A0A8I5Y144 A0A8I5ZZ84 A0A8I6A609 A0A8I6ACQ6 A0A8I6AN52 B1WBS6 D3ZE16 D3ZUM4 D3ZZL3 F1LLW8 P06760 P13265 P25304 P26260 P33671 P34900 P34901 P35053 P51653 Q5XIL5 Q642B0 Q71RP1	Agrin Agrn Glb1 Glb1l Glb1l2 Glb1l3 Gpc1 Gpc2 Gpc3 Gpc4 Gpc5 Gpc6 Gus Gusb Hep Hpse Hpse2 Hspg1 Ids Idua LOC100363795 Naglu Sdc1 Sdc2 Sdc3 Sdc4 Sgsh Synd1 Synd2 Synd3 Synd4	Rattus norvegicus (Norway rat)	G01550VL G09546QO
Keratan sulfate degradation	Aggrecan core protein Beta-galactosidase-1-like protein 3 Beta-galactosidase Beta-galactosidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta Fibromodulin Galactosidase, beta 1-like Keratocan Lumican N-acetylglucosamine-6-sulfatase Osteomodulin Prolargin	A0A8I5Y144 B1WBS6 D3ZUM4 D3ZVD7 P07897 P50609 P51886 Q32KJ5 Q5XIL5 Q641X3 Q6AXR4 Q9EQP5 Q9Z1S7	Acan Agc Agc1 Fmod Glb1 Glb1l Glb1l2 Glb1l3 Gns Hexa Hexb Kera Lcn Ldc Lum Omd Prelp	Rattus norvegicus (Norway rat)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
MET activates RAS signaling	GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I5Y176 A0A8I6AAU0 D3Z7Z5 D4A3T0 P08644 P17945 P20171 P62994 P97523 Q04970 Q5M824	Ash Grb2 Hgf Hras Hras1 Kras Kras2 Met Muc20 Nras Ranbp10 Ranbp9 Shc1 Sos1	Rattus norvegicus (Norway rat)
L1CAM interactions	Acyl-protein thioesterase 2 Neural cell adhesion molecule L1 Neuromodulin Ran-binding protein 9	A0A8I5Y176 P07936 Q05695 Q9QYL8	Caml1 Gap43 L1cam Lypla2 Ranbp9	Rattus norvegicus (Norway rat)
Downregulation of ERBB2 signaling	Betacellulin Cullin-5 Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Megakaryocyte-associated tyrosine-protein kinase Neuregulin 3 Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Tyrosine-protein phosphatase non-receptor type 12 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A8I5Y1H8 A0A8I6A5Y3 A0A8I6AHV1 A0A8I6AQ55 G3V6K6 G3V7Q4 O35569 P06494 P07522 P0CG51 P41243 P43322 P62982 P82995 Q06175 Q62799 Q63429 Q63692 Q9JJ31 Q9Z0L5	Batk Btc Cdc37 Ctk Cul5 Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Hsp86 Hsp90aa1 Hspca LOC100360645 Matk Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Ptpn12 Ptpn18 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vacm1	Rattus norvegicus (Norway rat)
ERBB2 Activates PTK6 Signaling	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Tyrosine-protein kinase	A0A8I5Y1H8 A0A8I6AQ55 D3ZDS3 G3V6K6 O35569 P06494 P07522 P43322 Q06175 Q62799 Q9Z0L5	Btc Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Ptk6	Rattus norvegicus (Norway rat)
GRB2 events in ERBB2 signaling	Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I5Y1H8 A0A8I6AQ55 D4A3T0 O35569 P06494 P08644 P20171 P43322 P62994 Q04970 Q06175 Q9Z0L5	Ash Btc Dtr Erbb2 Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Ndf Neu Nras Nrg1 Nrg2 Nrg3 Ntak Sos1	Rattus norvegicus (Norway rat)
SHC1 events in ERBB4 signaling	Betacellulin GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I5Y1H8 A0A8I6AQ55 D4A3T0 O35569 P08644 P20171 P43322 P62994 Q04970 Q06175 Q5M824 Q9Z0L5	Ash Btc Dtr Ereg Grb2 Hbegf Hegfl Hras Hras1 Kras Kras2 Ndf Nras Nrg1 Nrg2 Nrg3 Ntak Shc1 Sos1	Rattus norvegicus (Norway rat)
Signaling by ERBB2	Betacellulin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Yes	A0A8I5Y1H8 A0A8I6AQ55 F1LM93 G3V6K6 O35569 P06494 P07522 P43322 P82995 Q06175 Q62799 Q62844 Q63692 Q9WUD9 Q9Z0L5	Btc Cdc37 Dtr Egf Egfr Erbb2 Erbb3 Ereg Fyn Hbegf Hegfl Hsp86 Hsp90aa1 Hspca Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Src Yes1	Rattus norvegicus (Norway rat)
ERBB2 Regulates Cell Motility	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Protein MEMO1 Protein diaphanous homolog 1 Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 Transforming protein RhoA	A0A8I5Y1H8 A0A8I6AQ55 F1M775 G3V6K6 O35569 P06494 P07522 P43322 P61589 Q06175 Q4QQR9 Q62799 Q9Z0L5	Arha Arha2 Btc Diap1 Diaph1 Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Memo1 Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Rhoa	Rattus norvegicus (Norway rat)
SHC1 events in ERBB2 signaling	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Protein kinase C alpha type Protein kinase C delta type Protein kinase C epsilon type Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-2 Receptor tyrosine-protein kinase erbB-3 SHC-transforming protein 1 Tyrosine-protein phosphatase non-receptor type 12	A0A8I5Y1H8 A0A8I6AQ55 G3V6K6 G3V7Q4 O35569 P05696 P06494 P07522 P09215 P09216 P43322 Q06175 Q5M824 Q62799 Q9Z0L5	Btc Dtr Egf Egfr Erbb2 Erbb3 Ereg Hbegf Hegfl Ndf Neu Nrg1 Nrg2 Nrg3 Ntak Pkca Pkcd Pkce Prkca Prkcd Prkce Ptpn12 Shc1	Rattus norvegicus (Norway rat)
Signaling by ERBB4	Betacellulin Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Proepiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor tyrosine-protein kinase erbB-3	A0A8I5Y1H8 A0A8I6AQ55 G3V6K6 O35569 P07522 P43322 Q06175 Q62799 Q9Z0L5	Btc Dtr Egf Egfr Erbb3 Ereg Hbegf Hegfl Ndf Nrg1 Nrg2 Nrg3 Ntak	Rattus norvegicus (Norway rat)
Metalloprotease DUBs	Abraxas 2, BRISC complex subunit BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein homolog Histone H2A type 2-A Histone H2A type 3 Histone H2A.J Histone H2A Histone H2A Histone H2A Histone acetyltransferase Lys-63-specific deubiquitinase BRCC36 Myb-like, SWIRM and MPN domain-containing protein 1 NACHT, LRR and PYD domains-containing protein 3 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 STAM binding protein-like 1 STAM-binding protein Signal transducing adaptor molecule Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein histone acetyltransferase	A0A8I5Y222 A0A8I5ZYY0 A0A8I6A5Y3 A0A8I6AWT3 A0A8I6G641 A9UMV8 B2RYM5 B5DF55 D3ZVK7 D4A415 D4A523 D4A7T9 M0RA63 O54952 P0CC09 P0CG51 P62982 Q4FZT6 Q4V8E2 Q5I0F1 Q5PQK4 Q5XIJ6 Q63429 Q6P7Q1 Q8R424 Q9QZH2	ABRAXAS1 Abra1 Abraxas2 Amsh Babam1 Babam2 Bard1 Brca1 Brcc3 Brcc36 Bre Ccdc98 ENSRNOG00000062927 Ep300 Fam175a Fam175b H2ac10 H2ac18 H2ac25 H2ac4 H2aj Hist2h2aa3 Hist3h2a Kat2b LOC100360645 LOC120097726 Merit40 Mysm1 Nba1 Nlrp3 Psmd14 Rap80 Rps27a Stam Stambp Stambpl1 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Uimc1	Rattus norvegicus (Norway rat)
HSP90 chaperone cycle for SHRs	Actin related protein 10 Alpha-centractin Androgen receptor Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 DnaJ (Hsp40) homolog, subfamily A, member 4 DnaJ heat shock protein family (Hsp40) member B1 DnaJ homolog subfamily A member 1 DnaJ homolog subfamily A member 2 Dynactin 3-like 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Glucocorticoid receptor Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Mineralocorticoid receptor Peptidyl-prolyl cis-trans isomerase FKBP4 Progesterone receptor Prostaglandin E synthase 3 Stress-induced-phosphoprotein 1 peptidylprolyl isomerase	A0A8I5Y4I3 A0A8I6AIV4 A0A8I6B4B1 A0A8I6GBD2 B2GUZ5 D3ZUU5 F7EYK0 O35814 O35824 P06536 P0DMW0 P0DMW1 P14659 P15207 P22199 P28023 P34058 P38650 P55063 P63018 P63036 P63170 P82995 P83868 P85515 Q3T1K5 Q4QR73 Q5XI32 Q62698 Q62871 Q63100 Q63449 Q6AYH5 Q78P75 Q9QUR2 Q9QVC8 Q9QXU8 Q9WUV6	AABR07000222.1 Actr10 Actr1a Ar Capza1 Capza2 Capza3 Capzb Ctrn1 Dctn1 Dctn2 Dctn3l1 Dctn4 Dctn5 Dctn6 Dhc1 Dlc2 Dnaja1 Dnaja2 Dnaja4 Dnajb1 Dnch1 Dnchc1 Dnci1 Dnci2 Dncic1 Dncic2 Dncl1 Dnclc1 Dncli1 Dncli2 Dnec1 Dyhc Dync1h1 Dync1i1 Dync1i2 Dync1li1 Dync1li2 Dynll1 Dynll2 Fkbp4 Fkbp5 Fkbp52 Grl Hop Hsc70 Hsc73 Hsj2 Hsp70-1 Hsp70-2 Hsp70-3 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hspc3 Hspca Hspcb Hst70 Map1c Mlr Nr3c1 Nr3c2 Nr3c3 Nr3c4 Pgr Pin Ptges3 Rdj1 Stip1 Tebp	Rattus norvegicus (Norway rat)

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