GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **651 - 675** of **1070** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
PKA-mediated phosphorylation of key metabolic factors	Carbohydrate-responsive element-binding protein	Q8VIP2	Mlxipl Wbscr14	Rattus norvegicus (Norway rat)
PKMTs methylate histone lysines	AE binding protein 2 ASH1 like histone lysine methyltransferase ASH2 like histone lysine methyltransferase complex subunit Actin-histidine N-methyltransferase Activating transcription factor 7 interacting protein Embryonic ectoderm development Euchromatic histone lysine methyltransferase 1 Euchromatic histone lysine methyltransferase 2 Histone H3.1 Histone H3 Histone H4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase KMT5B Histone-lysine N-methyltransferase KMT5C Histone-lysine N-methyltransferase PRDM9 Histone-lysine N-methyltransferase SETD7 Histone-lysine N-methyltransferase SETDB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific Histone-lysine N-methyltransferase Histone-lysine N-methyltransferase Histone-lysine N-methyltransferase N-lysine methyltransferase SETD6 N-lysine methyltransferase SMYD2 Nuclear factor kappa B subunit 2 Nuclear receptor binding SET domain protein 1 Nuclear receptor binding SET domain protein 2 Nuclear receptor binding SET domain protein 3 PR/SET domain 16 RB binding protein 4, chromatin remodeling factor RB binding protein 5, histone lysine methyltransferase complex subunit RELA proto-oncogene, NF-kB subunit SET domain bifurcated histone lysine methyltransferase 1 SET domain containing 1A, histone lysine methyltransferase SET domain containing 1B, histone lysine methyltransferase SUZ12 polycomb repressive complex 2 subunit WD repeat-containing protein 5 [histone H3]-lysine(36) N-trimethyltransferase [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-trimethyltransferase [histone H4]-lysine(20) N-methyltransferase	A0A096MKA6 A0A0G2K001 A0A0G2K1E3 A0A0G2K6T6 A0A0G2K889 A0A8I5ZMV7 A0A8I5ZRT2 A0A8I6A054 A0A8I6A0F7 A0A8I6A1E5 A0A8I6A3A4 A0A8I6A4Z1 A0A8I6A5I9 A0A8I6AIG5 A0A8I6AMN8 A0A8I6ANV4 A0A8I6AQI0 A0A8I6G6F3 A0A8I6GKG3 A0A8J8XWH8 A0A8J8YPE2 B5DFE2 D3ZC01 D3ZIH5 D3ZJ08 D3ZS88 D3ZSK5 D3ZTV7 D4A081 D4A9J4 F1M0L3 G3V6U9 M0R6H5 P0C2N5 P0C2N6 P0C6Y7 P62804 Q498M4 Q4V8B9 Q6LED0 Q71UF4 Q7M6Z3	Aebp2 Ash1l Ash2l Atf7ip Dot1l Eed Ehmt1 Ehmt2 Ezh2 H3c13 H4c16 H4c2 H4f16 H4ft Hist1h4b Hist1h4m Hist2h3c2 Hist4 Hist4h4 Kmt2a Kmt2b Kmt2c Kmt5a Kmt5b Kmt5c LOC120093163 LOC498295 Mll Mll1 Nfkb2 Nsd1 Nsd2 Nsd3 Prdm16 Prdm9 Rbbp4 Rbbp5 Rbbp7 Rela Setd1a Setd1b Setd2 Setd3 Setd6 Setd7 Setdb1 Setdb2 Smyd2 Smyd3 Suv39h1 Suv39h2 Suv420h1 Suv420h2 Suz12 Wdr5 Whsc1 Whsc1l1	Rattus norvegicus (Norway rat)
PKR-mediated signaling	Alpha-synuclein Cellular tumor antigen p53 Cyclin-dependent kinase 1 Cytoplasmic protein DnaJ homolog subfamily C member 3 Double-stranded RNA-specific adenosine deaminase FA complementation group A FA complementation group B FA complementation group E FA complementation group F FA complementation group G FA complementation group L FA complementation group M FA core complex associated protein 100 FA core complex associated protein 24 Fanconi anemia core complex-associated protein 20 Fanconi anemia group C protein homolog Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock-related 70 kDa protein 2 ISG15 ubiquitin-like modifier Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced, double-stranded RNA-activated protein kinase Interferon-inducible double-stranded RNA-dependent protein kinase activator A Interleukin enhancer-binding factor 2 Interleukin enhancer-binding factor 3 Microtubule-associated protein tau Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleophosmin Protein phosphatase 2 scaffold subunit A alpha RBR-type E3 ubiquitin transferase RISC-loading complex subunit TARBP2 RNA helicase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Sphingosine kinase 1 Tripartite motif-containing 25 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin/ISG15-conjugating enzyme E2 L6 mitogen-activated protein kinase kinase	A0A0G2JWL4 A0A0G2JX93 A0A0G2K7F0 A0A8I5ZNL4 A0A8I6ABZ7 A0A8I6AGX8 A0A8I6AH74 A0A8I6ANR6 B2RZ33 D3ZAU3 D3ZDI7 D3ZE71 D3ZXL1 D4A3X3 D4A5I2 D4A9N5 D4AAA5 F1M0R6 F1M286 O35870 P0DMW0 P0DMW1 P10361 P13084 P14659 P19332 P35233 P37377 P39951 P52631 P55063 P55266 P62716 P63018 P63331 Q3SWU0 Q4QQT4 Q4V8C7 Q4V8J2 Q5XI34 Q63184 Q66HG9 Q6TMG5 Q7TP98 Q91V26 Q925D6 Q9JIL3 Q9QY78 Q9R0T3	Adar Arih1 Cdc2 Cdc2a Cdk1 Cdkn1 Chuk Dhx9 Dnajc3 Dsrad Eif2ak2 Faap100 Faap20 Faap24 Facc Fanca Fancb Fancc Fance Fancf Fancg Fancl Fancm Hsc70 Hsc73 Hsp70-1 Hsp70-2 Hsp70-3 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hst70 Ikbkb Ikbkg Ikkb Ilf2 Ilf3 Ips1 Isg15 Map2k6 Mapt Mavs Mkk6 Mtapt Nck1 Nemo Npm1 P53 P58ipk Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5a Prkr Prkra Ptpn2 RGD1564719 Snca Sphk1 Stat1 Stat3 Stat4 Tarbp2 Tau Tp53 Trim25 Ube2l6 Visa	Rattus norvegicus (Norway rat)
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha	A0A8J8XRQ3 O88302 O89040 P10687 P82471 Q99JE6 Q9JID2 Q9QW07	Gna11 Gna14 Gna15 Gnaq Plcb1 Plcb2 Plcb3 Plcb4	Rattus norvegicus (Norway rat)
PRC2 methylates histones and DNA	AE binding protein 2 DNA (cytosine-5)-methyltransferase 1 DNA (cytosine-5)-methyltransferase 3A DNA (cytosine-5-)-methyltransferase Embryonic ectoderm development Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Jumonji and AT-rich interaction domain containing 2 Metal response element binding transcription factor 2 PHD finger protein 19 PHD finger protein 1 RB binding protein 4, chromatin remodeling factor SUZ12 polycomb repressive complex 2 subunit	A0A0G2JXI9 A0A0G2K557 A0A8I5ZSA8 A0A8I5ZSG2 A0A8I5ZYY0 A0A8I6A054 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AIG5 A0A8I6AQI0 A0A8I6AWT3 A0A8I6G659 A0A8J8XG14 A0A8J8YPE2 A9UMV8 B5DFE2 D3ZJ08 D3ZVK7 D3ZXP3 D4ACM0 F1M1Y4 G3V9C7 M0RBQ5 M0RBV7 P0CC09 P62804 P84245 Q00729 Q1LZ53 Q6LED0 Q71UF4 Q9Z330	Aebp2 Dnmt1 Dnmt3a Dnmt3b ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Eed Ezh2 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Jarid2 LOC100365043 LOC100910200 LOC120097726 LOC681740 LOC684797 Mtf2 Phf1 Phf19 Rbbp4 Rbbp7 Suz12 Th2b	Rattus norvegicus (Norway rat)
PRPP biosynthesis	Ribose-phosphate pyrophosphokinase 1 Ribose-phosphate pyrophosphokinase 1 Ribose-phosphate pyrophosphokinase 2 Ribose-phosphate pyrophosphokinase N-terminal domain-containing protein ribose-phosphate diphosphokinase	A0A0G2JSV3 A0A8I6AC83 M0RBK1 P09330 P60892	ENSRNOG00000063771 LOC314140 Prps1 Prps1l1 Prps1l3 Prps2	Rattus norvegicus (Norway rat)
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Tyrosine-protein kinase	D3ZDS3 O08769 P35426 P39948 P39949 Q63699	Ccnd1 Ccne Ccne1 Cdk2 Cdk4 Cdkn1b Cdkn2 Ptk6 p27Kip1	Rattus norvegicus (Norway rat)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Engulfment and cell motility 1 Engulfment and cell motility 2 GTPase HRas GTPase KRas GTPase NRas Paxillin Ras GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Transforming protein RhoA Tyrosine-protein kinase	D3ZDS3 D3ZY46 G3V982 P08644 P20171 P50904 P61589 P81128 Q04970 Q63767 Q63768 Q66H76 Q6RUV5	Arha Arha2 Arhgap35 Bcar1 Cas Crk Crkas Crko Elmo1 Elmo2 Grlf1 Hras Hras1 Kras Kras2 Nras P190A Ptk6 Pxn Rac Rac1 Rasa Rasa1 Rhoa p190ARHOGAP	Rattus norvegicus (Norway rat)
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 Docking protein 1 E3 ubiquitin-protein ligase CBL Polyubiquitin-B Polyubiquitin-C RAC-alpha serine/threonine-protein kinase Tyrosine-protein kinase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I6A5Y3 A0A8I6AQA1 A0A8I6G3R2 D3ZDS3 P0CG51 P47196 P62982 Q4QQV2 Q63429	Akt1 Arap1 Cbl Dok1 LOC100360645 Ptk6 Rps27a Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
PTK6 promotes HIF1A stabilization	Hypoxia-inducible factor 1-alpha Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transmembrane glycoprotein NMB Tyrosine-protein kinase non-specific serine/threonine protein kinase	D3ZDS3 F1LNJ1 G3V6K6 O35800 Q06175 Q6P7C7	Dtr Egfr Gpnmb Hbegf Hegfl Hif1a Lrrk2 Ptk6	Rattus norvegicus (Norway rat)
Passive transport by Aquaporins	Aquaporin 10 Aquaporin-11 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin-7 Aquaporin-8 Aquaporin-9 Aquaporin Lens fiber major intrinsic protein (Fragment)	A0A8I6A7W7 D4A9T6 P09011 P29975 P34080 P47862 P47863 P47864 P56403 P56405 P56627 Q8CHM1	Aqp1 Aqp10 Aqp11 Aqp12a Aqp2 Aqp3 Aqp4 Aqp5 Aqp7 Aqp8 Aqp9 Chip28 LOC686596 Mip	Rattus norvegicus (Norway rat)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A8I6A8V2 A0A8I6G4T5 A0A8I6GEB4 D4A7L6 F7FLB2 P05370 P50137 P85968 P85971 Q9EQS0	Dera G6pd G6pdx Pgd Pgls Pgm2 RBKS Rbks Rpe Rpia Taldo1 Tkt	Rattus norvegicus (Norway rat)	G31080DL
Peptide chain elongation	Elongation factor 2	P05197	Eef2	Rattus norvegicus (Norway rat)
Peptide hormone biosynthesis	Neuroendocrine convertase 1 Pro-opiomelanocortin	P01194 P28840	Bdp Nec-1 Nec1 Pcsk1 Pomc Pomc2	Rattus norvegicus (Norway rat)
Peptide ligand-binding receptors	Adrenocorticotropic hormone receptor Angiotensinogen Apelin receptor Apelin B1 bradykinin receptor B2 bradykinin receptor Bombesin receptor subtype-3 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 C5a anaphylatoxin chemotactic receptor 2 Cholecystokinin receptor type A Cholecystokinin Complement C3 Complement C5 Delta-type opioid receptor Endoplasmic reticulum membrane adapter protein XK Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Endothelin-converting enzyme 1 G-protein coupled estrogen receptor 1 G-protein coupled receptor 37-like 1 Galanin peptides Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3 Gastrin-releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Kappa-type opioid receptor Kell metallo-endopeptidase (Kell blood group) KiSS-1 receptor Kininogen-1 Melanin-concentrating hormone receptor 1 Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Metastasis-suppressor KiSS-1 Mu-type opioid receptor Neurolysin, mitochondrial Neuromedin B Neuromedin-B receptor Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide B Neuropeptide S receptor Neuropeptide S Neuropeptide W Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 4 Neuropeptide Y receptor type 5 Neuropeptides B/W receptor type 1 Neurotensin receptor type 1 Neurotensin receptor type 2 Neurotensin/neuromedin N Nociceptin receptor Pancreatic polypeptide prohormone Peptide YY Prepronociceptin Pro-MCH Pro-neuropeptide Y Pro-opiomelanocortin Pro-thyrotropin-releasing hormone Proenkephalin-A Proenkephalin-B Prokineticin receptor 1 Prokineticin receptor 2 Prokineticin-1 Prokineticin-2 Prolactin-releasing peptide receptor Prolactin-releasing peptide Prosaposin receptor GPR37 Prosaposin Proteinase-activated receptor 1 Proteinase-activated receptor 2 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4 Somatostatin receptor type 5 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor A Type-2 angiotensin II receptor Urotensin-2 receptor Urotensin-2 Urotensin-2B endothelin-converting enzyme 1	B6ZGR5 D4A1W6 D4A4U1 F1M761 G3V848 O08726 O08878 O55197 O88626 P01015 P01026 P01150 P01194 P01355 P04094 P06300 P06303 P07808 P08650 P08934 P0C0L6 P0C0P7 P10631 P10683 P10960 P12760 P13207 P14200 P18292 P20068 P20789 P21451 P21555 P22388 P23943 P24053 P24393 P25023 P25095 P26684 P26824 P28646 P30551 P30553 P30680 P30936 P30937 P30938 P32244 P33533 P33535 P34975 P35345 P35351 P35370 P42676 P42893 P49684 P52500 P60042 P70596 P81278 P97520 P97583 P97639 Q01717 Q56UD9 Q5GH61 Q5H8A2 Q62805 Q62923 Q63384 Q63447 Q63634 Q63645 Q64121 Q695P6 Q765I2 Q7TSB7 Q8K1M5 Q8K418 Q8K4P2 Q8R413 Q8R414 Q8R415 Q8R416 Q920E0 Q920E1 Q924U1 Q9ESQ4 Q9JHG3 Q9JJI5 Q9QYC5 Q9QYC6 Q9QZQ4 Q9R0R3	Agt Agtr1 Agtr1a Agtr2 Agtrl1 Apel Apj Apln Aplnr At1a B1bkr Bdkrb1 Bdkrb2 Bkr Brs3 Bv8 C3 C3ar1 C5 C5ar1 C5ar2 C5l2 C5r1 Cck Cckar Cckbr Cmkrl2 Ece1 Ece2 Edn1 Edn2 Edn3 Ednra Ednrb Etbrlp2 F2 F2r F2rl1 F2rl2 F2rl3 Gal Galn Galnr Galnr1 Galnr2 Galnr3 Galr1 Galr2 Galr3 Gper Gper1 Gpr10 Gpr14 Gpr154 Gpr24 Gpr30 Gpr37 Gpr37l1 Gpr41 Gpr54 Gpr66 Gpr7 Gpr73 Gpr73l1 Gpr77 Grp Grpr Kel Kiss1 Kiss1r Kng Kng1 Mc1r Mc2r Mc3r Mc4r Mc5r Mch Mchr1 Nln Nmb Nmbr Nms Nmu Nmur1 Nmur2 Npb Npbwr1 Nps Npsr1 Npw Npy Npy1r Npy4r Npy5r Npyr5 Ntr2 Nts Ntsr Ntsr1 Ntsr2 Oor Oprd1 Oprk1 Oprl Oprl1 Oprm1 Par1 Par2 Par3 Par4 Pdyn Penk Penk-rs Penk1 Pkr1 Pkr2 Pmch Pnoc Pomc Pomc2 Ppl8 Ppy Ppyr1 Prh Prlh Prlhr Prok1 Prok2 Prokr1 Prokr2 Psap Pyy Ror-a Ror-b Ror-d Senr Serpina8 Sgp1 Slc1 Smst Sst Sstr1 Sstr2 Sstr3 Sstr4 Sstr5 Tgr1 Trh Trhr Urp Uts2 Uts2b Uts2d Uts2r Xk Xkh Xkr1 Xrg1	Rattus norvegicus (Norway rat)
Peroxisomal lipid metabolism	2-Hydroxyacid oxidase 2 Acyl-CoA-binding domain-containing protein 4 Acyl-CoA-binding domain-containing protein 5 Acyl-coenzyme A diphosphatase NUDT19	A0FKI7 Q07523 Q6AYD9 Q6DGF9	Acbd4 Acbd5 Hao2 Hao3 Haox2 Nudt19	Rattus norvegicus (Norway rat)
Peroxisomal protein import	2-Hydroxyacid oxidase 1 2-Hydroxyacid oxidase 2 2-hydroxyacyl-CoA lyase 1 3-ketoacyl-CoA thiolase B, peroxisomal AN1-type zinc finger protein 6 Acyl-CoA thioesterase 3 Acyl-CoA thioesterase 4 Acyl-CoA thioesterase 5 Acyl-coenzyme A diphosphatase NUDT19 Acyl-coenzyme A thioesterase 1 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 8 Alanine--glyoxylate aminotransferase Alkyldihydroxyacetonephosphate synthase, peroxisomal Alpha-methylacyl-CoA racemase Bifunctional epoxide hydrolase 2 Bile acid-CoA Carnitine O-acetyltransferase Catalase D-amino-acid oxidase D-aspartate oxidase Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Enoyl-CoA delta isomerase 2 Glutathione S-transferase kappa 1 Hydroxymethylglutaryl-CoA lyase, mitochondrial Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] cytoplasmic Lon protease homolog 2, peroxisomal Long-chain fatty acid transport protein 2 Malonyl-CoA decarboxylase, mitochondrial Nitric oxide synthase, inducible Nudix hydrolase 7 Peroxin-7 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal ATPase PEX1 Peroxisomal ATPase PEX6 Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal bifunctional enzyme Peroxisomal carnitine O-octanoyltransferase Peroxisomal leader peptide-processing protease Peroxisomal membrane protein PEX14 Peroxisomal multifunctional enzyme type 2 Peroxisomal targeting signal 1 receptor Peroxisomal trans-2-enoyl-CoA reductase Peroxisome assembly protein 12 Peroxisome biogenesis factor 2 Phytanoyl-CoA dioxygenase, peroxisomal Polyamine oxidase Polyubiquitin-B Polyubiquitin-C Protein Mpv17 RING-type E3 ubiquitin transferase Sterol carrier protein 2 Ubiquitin B-like Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eS31 fusion protein sarcosine oxidasee (formaldehyde-forming)	A0A8I6A5Y3 A0A8I6A6H9 A1A5R4 B0BNF9 B1H261 D3Z8W0 D3ZC81 D3ZDK2 D3ZDM7 D3ZIQ1 D3ZV74 D3ZZB2 O35078 O55171 O88177 O88267 P04762 P07871 P07872 P07896 P09139 P0CG51 P11466 P11915 P24392 P24473 P35559 P41562 P54777 P57093 P61078 P62839 P62982 P70473 P80299 P97519 P97524 P97562 P97852 Q06518 Q07523 Q2M2R8 Q3MIB4 Q498S5 Q5BK62 Q5I0K1 Q5XIC0 Q62651 Q63276 Q63429 Q63448 Q642G4 Q6AYD9 Q6DGF4 Q704S8 Q8CHM7 Q8VHK0 Q8VID1 Q920F5 Q9EQR2 Q9ES71 Q9WVK3 Q9Z2M4	2hpcl AC094055.1 Acaa1 Acaa1b Acot1 Acot2 Acot3 Acot4 Acot5 Acot8 Acox Acox1 Acox2 Acox3 Acsvl1 Ads Agps Agt1 Agxt Amacr Baat Cas1 Cat Cot Crat Crot Cte1 Dao Dao1 Ddo Decr2 Dhrs4 Ech1 Eci2 Edh17b4 Ehhadh Ephx2 Facvl1 Fatp2 Gnpat Gstk1 Hacl1 Hao1 Hao2 Hao3 Haox2 Hmgcl Hpcl2 Hsd17b4 Ide Idh1 LOC100360645 LOC100911156 Lonp2 Mfe1 Mlycd Mpv17 Mpv17l Mte1 Nos2 Nudt19 Nudt7 Paf1 Paf3 Paox Peci Pecr Pex1 Pex10 Pex12 Pex14 Pex2 Pex5 Pex5_predicted Pex6 Pex7 Phyh Phyh2 Pipox Pmp35 Prcox Pte1 Pxmp3 Rps27a Scp-2 Scp2 Slc27a2 Thcox Tysnd1 Uba80 Ubb Ubbl1 Ubc Ubc4 Ubcep1 Ubch4 Ubch5b Ubcl1 Ube2d1 Ube2d2 Ube2d3 Vlacs Vlcs Za20d3 Zfand6	Rattus norvegicus (Norway rat)
Phase 0 - rapid depolarisation	Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-6 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2	P22002 P54283 P62957 Q8CFG6 Q8VGC3 Q8VHW5 Q8VHW7 Q8VHW9	Cach2 Cacn2 Cacna1c Cacna2d2 Cacnb1 Cacnb2 Cacng4 Cacng6 Cacng7 Cacng8 Cacnl1a1 Cacnlb1 Cacnlb2 Cchl1a1	Rattus norvegicus (Norway rat)
Phase 2 - plateau phase	A-kinase anchoring protein 9 Potassium voltage-gated channel subfamily E member 2 Potassium voltage-gated channel subfamily E member 3 Potassium voltage-gated channel subfamily E regulatory subunit 4 Potassium voltage-gated channel subfamily E regulatory subunit 5 Potassium voltage-gated channel subfamily KQT member 1 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-6 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2	A0A0G2K548 A5HKJ1 P22002 P54283 P62957 P63161 Q71FD8 Q8CFG6 Q8VGC3 Q8VHW5 Q8VHW7 Q8VHW9 Q9JJV7 Q9Z0N7	Akap9 Cach2 Cacn2 Cacna1c Cacna2d2 Cacnb1 Cacnb2 Cacng4 Cacng6 Cacng7 Cacng8 Cacnl1a1 Cacnlb1 Cacnlb2 Cchl1a1 Kcna9 Kcne1l Kcne2 Kcne3 Kcne4 Kcne5 Kcnq1 Kvlqt1	Rattus norvegicus (Norway rat)
Phase 3 - rapid repolarisation	A-kinase anchoring protein 9 Potassium voltage-gated channel subfamily A member 5 Potassium voltage-gated channel subfamily E member 2 Potassium voltage-gated channel subfamily E member 3 Potassium voltage-gated channel subfamily E regulatory subunit 4 Potassium voltage-gated channel subfamily E regulatory subunit 5 Potassium voltage-gated channel subfamily H member 2 Potassium voltage-gated channel subfamily KQT member 1	A0A0G2K548 A5HKJ1 O08962 P19024 P63161 Q71FD8 Q9JJV7 Q9Z0N7	Akap9 Erg Kcna5 Kcna9 Kcne1l Kcne2 Kcne3 Kcne4 Kcne5 Kcnh2 Kcnq1 Kvlqt1	Rattus norvegicus (Norway rat)
Phase 4 - resting membrane potential	ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 14 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4 Potassium channel subfamily K member 10 Potassium channel subfamily K member 12 Potassium channel subfamily K member 13 Potassium channel subfamily K member 15 Potassium channel subfamily K member 18 Potassium channel subfamily K member 1 Potassium channel subfamily K member 2 Potassium channel subfamily K member 3 Potassium channel subfamily K member 4 Potassium channel subfamily K member 9 Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel, subfamily K, member 5 Potassium two pore domain channel subfamily K member 16	D3ZLR9 D4A806 G3V8R8 G3V8V5 O54912 O70596 P52188 P52190 Q2KTA6 Q64273 Q6Q1P3 Q8R5I0 Q920B6 Q9ERS0 Q9ERS1 Q9ES08 Q9JIS4 Q9Z2T2	Irk1 Irk2 Irk3 Irk4 Kcnj12 Kcnj14 Kcnj2 Kcnj4 Kcnk1 Kcnk10 Kcnk12 Kcnk13 Kcnk15 Kcnk16 Kcnk18 Kcnk2 Kcnk3 Kcnk4 Kcnk5 Kcnk6 Kcnk7 Kcnk9 LOC364241 Task Task1 Task3 Task5 Trek Trek2 Tresk-2 Tresk2	Rattus norvegicus (Norway rat)
Phase I - Functionalization of compounds	Aldehyde dehydrogenase, dimeric NADP-preferring Amine oxidase [copper-containing] 3 Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Biphenyl hydrolase like Carbonyl reductase [NADPH] 3 Carboxylesterase 1D Carboxylic ester hydrolase Carboxymethylenebutenolidase homolog Cytochrome P450 3A18 Cytochrome P450 3A1 Cytochrome P450 3A2 Cytochrome P450 3A9 Cytochrome P450 3A Cytochrome P450 Cytochrome b5 type B Diamine oxidase [copper-containing] Epoxide hydrolase 1 Mitochondrial amidoxime reducing component 2 NADH-cytochrome b5 reductase 3 Ribosyldihydronicotinamide dehydrogenase [quinone]	A0A0G2K5K4 B2GV72 F7FBS0 G3V9D2 M0R9W7 O08590 O88994 P04166 P04800 P05183 P07687 P11883 P16303 P20070 P36633 P41738 P41739 P51538 Q64581 Q6AY80 Q75NT5 Q78E60 Q7TP52 Q9QZH8	Aada Aadac Abp1 Ahr Ahrr Aldd Aldh3 Aldh3a1 Aoc1 Aoc3 Arnt Arnt2 Bphl Cbr3 Ces1d Ces2b Ces3 Cmbl Cyb5b Cyb5m Cyb5r3 Cyp2b21 Cyp3a-1 Cyp3a-2 Cyp3a1 Cyp3a11 Cyp3a13 Cyp3a18 Cyp3a2 Cyp3a62 Cyp3a9 Dia1 Eph-1 Ephx1 LOC679149 Marc2 Mg87 Mosc2 Mtarc2 Nqo2 Omb5	Rattus norvegicus (Norway rat)
Phosphate bond hydrolysis by NTPDase proteins	Ectonucleoside triphosphate diphosphohydrolase 1 Ectonucleoside triphosphate diphosphohydrolase 2 Ectonucleoside triphosphate diphosphohydrolase 3 Ectonucleoside triphosphate diphosphohydrolase 4 Ectonucleoside triphosphate diphosphohydrolase 5 Ectonucleoside triphosphate diphosphohydrolase 6 Ectonucleoside triphosphate diphosphohydrolase 7 Ectonucleoside triphosphate diphosphohydrolase 8	A0A0G2JX61 A0A0G2K5S7 A0A8J8YF16 O35795 P97687 Q5DRK1 Q6P6S9 Q9ER31	Cd39 Cd39l1 Cd39l2 Entpd1 Entpd2 Entpd3 Entpd4 Entpd5 Entpd6 Entpd7 Entpd8	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho	A0A8I6B5D5 F1LSQ8 P10686 P13109 P36364 P48807 P61149 P63076 P70492 Q04589 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9 Q9Z2Y9	FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Kl Plcg1	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A8I6B5D5 F1LSG7 F1LSQ8 O54769 O88182 P10686 P13109 P36364 P48807 P61149 P63076 P70492 Q02195 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9	FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-7 Fgf-9 Fgf1 Fgf10 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr2 Kgf Plcg1	Rattus norvegicus (Norway rat)

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