GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **726 - 750** of **1070** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
RUNX1 regulates transcription of genes involved in BCR signaling	Core-binding factor subunit beta Paired box 5 Runt-related transcription factor 1	A0A8I5ZL27 A0A8I6GMB2 Q63046	Aml1 Cbfa2 Cbfb Pax5 Runx1	Rattus norvegicus (Norway rat)
Creatine metabolism	Creatine kinase B-type Creatine kinase M-type Creatine kinase S-type, mitochondrial Creatine kinase U-type, mitochondrial Glycine amidinotransferase, mitochondrial Guanidinoacetate N-methyltransferase Sodium- and chloride-dependent GABA transporter 3 Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent creatine transporter 1 Sodium-dependent proline transporter	P00564 P07335 P09605 P10868 P25809 P28570 P28573 P31647 P48056 P50442	Agat Ckb Ckbb Ckm Ckmm Ckmt Ckmt1 Ckmt2 Gabt3 Gamt Gat-3 Gat-b Gatm Prot Slc6a11 Slc6a12 Slc6a7 Slc6a8	Rattus norvegicus (Norway rat)
Erythropoietin activates RAS	Crk-like protein Erythropoietin receptor Erythropoietin Growth factor receptor-bound protein 2 Insulin receptor substrate 2 Proto-oncogene vav Rap guanine nucleotide exchange factor 1 SHC-transforming protein 1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	F1M8L9 F1MAL5 P29676 P54100 P62994 Q07014 Q07303 Q5M824 Q5U2U2 Q62689	Ash Crkl Epo Epor Grb2 Irs2 Jak2 Lyn Rapgef1 Shc1 Vav Vav1	Rattus norvegicus (Norway rat)
Activation of the AP-1 family of transcription factors	Cyclic AMP-dependent transcription factor ATF-2 Mapk11 protein Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Protein c-Fos Transcription factor Jun	D4A3U7 P12841 P17325 P21708 P49185 P49186 P49187 P63086 P70618 Q00969	Atf2 Csbp1 Csbp2 Erk1 Erk2 Fos Jnk1 Jnk2 Jnk3 Jun Mapk Mapk1 Mapk10 Mapk11 Mapk14 Mapk3 Mapk8 Mapk9 Prkm1 Prkm10 Prkm3 Prkm8 Prkm9 Rjg-9	Rattus norvegicus (Norway rat)
ATF6 (ATF6-alpha) activates chaperones	Cyclic AMP-dependent transcription factor ATF-6 alpha Membrane-bound transcription factor site-1 protease	G3V909 Q9WTZ3	Atf6 Mbtps1 S1p Ski1	Rattus norvegicus (Norway rat)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Cyclic AMP-responsive element-binding protein 1 Cyclin-dependent kinase inhibitor 1B Exportin-1 Forkhead box O3 Mitogen-activated protein kinase 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein kinase Kist	D3ZBQ1 O08769 P15337 P47196 P47197 P63086 Q63285 Q63484 Q80U96	Akt1 Akt2 Akt3 Cdkn1b Creb-1 Creb1 Crm1 Erk2 Foxo3 Kis Kist Mapk Mapk1 Prkm1 Uhmk1 Xpo1 p27Kip1	Rattus norvegicus (Norway rat)
NGF-stimulated transcription	Cyclic AMP-responsive element-binding protein 1 DNA helicase E3 SUMO-protein ligase EGR2 Ngfi-A binding protein 2 Serine/threonine-protein kinase Sgk1 Serum response factor	A0A8I6B288 D3ZHH8 E9PU01 P15337 P51774 Q06226	Chd4 Creb-1 Creb1 Egr-2 Egr2 Krox-20 Krox20 Nab2 Sgk Sgk1 Srf	Rattus norvegicus (Norway rat)
NCAM signaling for neurite out-growth	Cyclic AMP-responsive element-binding protein 1 Focal adhesion kinase 1 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Receptor-type tyrosine-protein phosphatase alpha Ribosomal protein S6 kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 2 Spectrin beta chain Spectrin beta chain Spectrin beta chain Spectrin, alpha, erythrocytic 1 Spectrin, beta, non-erythrocytic 5 Tyrosine-protein kinase Fyn	A0A0G2JY25 A0A0G2K677 A0A8I6A7D1 A0A8I6AWM3 D4A3T0 D4A678 G3V6S0 O35346 P08644 P13596 P15337 P16086 P20171 P21708 P62994 P63086 Q03348 Q04970 Q62844 Q9QWN8	Ash Creb-1 Creb1 Erk1 Erk2 Fak Fak1 Fyn Grb2 Hras Hras1 Kras Kras2 Lrp Mapk Mapk1 Mapk3 Ncam Ncam1 Nras Prkm1 Prkm3 Ptk2 Ptpra Rps6ka5 Sos1 Spna2 Spnb3 Spta1 Spta2 Sptan1 Sptb Sptbn1 Sptbn2 Sptbn4 Sptbn5	Rattus norvegicus (Norway rat)
AKT phosphorylates targets in the nucleus	Cyclic AMP-responsive element-binding protein 1 Forkhead box O3 Forkhead box O4 Forkhead box O6 Forkhead box protein O1 Nuclear receptor subfamily 4 group A member 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ribosomal protein S6 kinase	A0A8I6A2S2 D3ZBQ1 D4A433 D4AE24 G3V7R4 P15337 P22829 P47196 P47197 Q63484	Akt1 Akt2 Akt3 Creb-1 Creb1 Foxo1 Foxo1a Foxo3 Foxo4 Foxo6 Hmr Ngfib Nr4a1 Rps6kb2	Rattus norvegicus (Norway rat)
Gastrin-CREB signalling pathway via PKC and MAPK	Cyclic AMP-responsive element-binding protein 1 Gastrin/cholecystokinin type B receptor Gastrin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A8I6AR08 A0A8I6AWJ2 P04563 P0C865 P15337 P21708 P30553 P63086 Q63531	Bmk1 Cckbr Creb-1 Creb1 Erk1 Erk2 Erk5 Gas Gast Mapk Mapk1 Mapk3 Mapk7 Mapkapk1a Prkm1 Prkm3 Rps6ka1 Rps6ka2 Rps6ka3 Rsk1	Rattus norvegicus (Norway rat)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	Cyclic AMP-responsive element-binding protein 1 Ribosomal protein S6 kinase A6 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A8I6AQN6 A0A8I6AR08 A0A8I6AWJ2 P15337 Q63531	Creb-1 Creb1 Mapkapk1a Rps6ka1 Rps6ka2 Rps6ka3 Rps6ka6 Rsk1	Rattus norvegicus (Norway rat)
Activation of the phototransduction cascade	Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 G protein subunit alpha transducin 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein subunit gamma Phosphodiesterase Phosphodiesterase Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin	A0A8I5ZN27 D3Z8C9 D3ZDI8 D3ZSS5 D4AAI1 M0R4R9 P51489 P54311 Q62927	CNCG2 CNCG3L CNCG4 Cncg Cncg1 Cnga1 Cngb1 Gnat1 Gnb1 Gngt1 Pde6a Pde6b Pde6g RCNC2 Rho	Rattus norvegicus (Norway rat)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	Cyclin E2 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1A Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1 Transcription factor E2F7 Transcription factor E2F8	A0A0G2JVY9 A0A8I5ZZ18 D3ZQ41 D4A4D7 F1LMN3 O08769 P39949 Q63699 Q6AY13	Ccna1 Ccna2 Ccne Ccne1 Ccne2 Cdk2 Cdkn1a Cdkn1b Cdkn2 E2f7 E2f8 p27Kip1	Rattus norvegicus (Norway rat)
p53-Dependent G1 DNA Damage Response	Cyclin E2 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1A Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1	A0A0G2JVY9 A0A8I5ZZ18 D3ZQ41 O08769 P39949 Q63699 Q6AY13	Ccna1 Ccna2 Ccne Ccne1 Ccne2 Cdk2 Cdkn1a Cdkn1b Cdkn2 p27Kip1	Rattus norvegicus (Norway rat)
MAPK3 (ERK1) activation	Cyclin-dependent kinase 1 Dual specificity mitogen-activated protein kinase kinase 1 Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Mitogen-activated protein kinase 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A8I6AM23 D3ZD03 P20607 P21708 P22273 P39951 P40190 P41499 Q01986 Q62689	Cdc2 Cdc2a Cdk1 Cdkn1 Erk1 Il-6 Il6 Il6r Il6ra Il6st Jak1 Jak2 Map2k1 Mapk3 Mek1 Prkm3 Prkmk1 Ptpn11 Tyk2	Rattus norvegicus (Norway rat)
Mitotic Prophase	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Nuclear mitotic apparatus protein 1	F1LW91 P30277 P39951	Ccnb1 Cdc2 Cdc2a Cdk1 Cdkn1 Numa1	Rattus norvegicus (Norway rat)
PTK6 Regulates Cell Cycle	Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-D1 G1/S-specific cyclin-E1 Tyrosine-protein kinase	D3ZDS3 O08769 P35426 P39948 P39949 Q63699	Ccnd1 Ccne Ccne1 Cdk2 Cdk4 Cdkn1b Cdkn2 Ptk6 p27Kip1	Rattus norvegicus (Norway rat)
CRMPs in Sema3A signaling	Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 Dihydropyrimidinase-related protein 1 Dihydropyrimidinase-related protein 2 Dihydropyrimidinase-related protein 3 Dihydropyrimidinase-related protein 4 (Fragment) Dihydropyrimidinase-related protein 5 Glycogen synthase kinase-3 beta Neuropilin-1 Plexin A1 Plexin A2 Plexin A4 Plexin-A3 Semaphorin-3A Tyrosine-protein kinase Fyn Tyrosine-protein kinase	A0A8I6AGW9 D3ZES7 D3ZPX4 D3ZWP6 D4A584 P18266 P47942 P61810 Q03114 Q62844 Q62950 Q62951 Q62952 Q63548 Q9JHU0 Q9QWJ9	Cdk5 Cdk5r Cdk5r1 Cdkn5 Crmp1 Crmp3 Crmp4 Dpysl1 Dpysl2 Dpysl3 Dpysl4 Dpysl5 Fes Fyn Gsk3b Nrp1 PSSALRE Plxna1 Plxna2 Plxna3 Plxna4 Plxna4a Sema3a Ulip4 Ulip6	Rattus norvegicus (Norway rat)
Leukotriene receptors	Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Uracil nucleotide/cysteinyl leukotriene receptor	Q09QM4 Q924T8 Q924T9 Q924U0 Q9R0Q2	Blt Cyslt1 Cyslt2 Cysltr1 Cysltr2 Gpr17 Ltb4r Ltb4r2	Rattus norvegicus (Norway rat)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi associated PDZ and coiled-coil motif containing Rho-related GTP-binding protein RhoQ	A0A8I5ZTW6 P34158 Q9JJL4	Abcc7 Cftr Gopc Rhoq Tc10	Rattus norvegicus (Norway rat)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	Cytochrome P450 1A1 Cytochrome P450 1A2 Cytochrome P450 1B1 Cytochrome P450 2C26-like Cytochrome P450 2U1 Cytochrome P450 4A12 Cytochrome P450 4F4	A0A8I6AFV7 P00185 P04799 P24464 P51869 Q4V8D1 Q64678	Cyp1a-1 Cyp1a-2 Cyp1a1 Cyp1a2 Cyp1b1 Cyp2c66 Cyp2u1 Cyp4a-8 Cyp4a12 Cyp4a8 Cyp4f4 LOC100912265	Rattus norvegicus (Norway rat)
Biosynthesis of protectins	Cytochrome P450 1A1 Cytochrome P450 1A2 Leukotriene A-4 hydrolase Polyunsaturated fatty acid lipoxygenase ALOX15	P00185 P04799 P30349 Q02759	Alox12l Alox15 Cyp1a-1 Cyp1a-2 Cyp1a1 Cyp1a2 Lta4h	Rattus norvegicus (Norway rat)
Biosynthesis of maresin-like SPMs	Cytochrome P450 1A2 Cytochrome P450 2C26-like Cytochrome P450 2D4 Cytochrome P450 2E1 Cytochrome P450 3A18 Cytochrome P450 3A1 Cytochrome P450 3A2 Cytochrome P450 3A9 Cytochrome P450 3A	A0A0G2K5K4 A0A8I6AFV7 P04799 P04800 P05182 P05183 P51538 Q64581 Q64680	Cyp1a-2 Cyp1a2 Cyp2c66 Cyp2d-18 Cyp2d-4 Cyp2d18 Cyp2d4 Cyp2e Cyp2e-1 Cyp2e1 Cyp3a-1 Cyp3a-2 Cyp3a1 Cyp3a11 Cyp3a13 Cyp3a18 Cyp3a2 Cyp3a62 Cyp3a9 LOC100912265	Rattus norvegicus (Norway rat)
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	Cytochrome P450 1A2	P04799	Cyp1a-2 Cyp1a2	Rattus norvegicus (Norway rat)
The canonical retinoid cycle in rods (twilight vision)	Cytochrome P450 4V2 LRRGT00111 Lecithin retinol acyltransferase Myosin VIIA Receptor for retinol uptake STRA6 Retinaldehyde binding protein 1 Retinoid isomerohydrolase Retinol binding protein 3 Retinol dehydrogenase 10 Retinol dehydrogenase 12 Retinol-binding protein 1 Retinol-binding protein 4 Rhodopsin Transthyretin	A0A8I5ZWB0 A2RRT9 D3Z956 D3ZEP9 G3V8Q4 O70276 P02696 P02767 P04916 P51489 Q4QR83 Q6TUD3 Q80ZF7 Q9JI61	Cyp4v2 Cyp4v3 Lrat Myo7a Rbp-1 Rbp1 Rbp3 Rbp4 Rdh10 Rdh11 Rdh12 Rho Rlbp1 Rpe65 Stra6 Tt Ttr	Rattus norvegicus (Norway rat)

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