GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **951 - 975** of **1070** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	F1MAL5 P01346 P08025 P24062 P35570	Igf-1 Igf-2 Igf1 Igf1r Igf2 Irs-1 Irs1 Irs2	Rattus norvegicus (Norway rat)
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	A0A0G2K344 F1MAL5 P35570 Q63787 Q63788 Q9Z1L0	Irs-1 Irs1 Irs2 Pik3ca Pik3cb Pik3r1 Pik3r2	Rattus norvegicus (Norway rat)
Signaling by Insulin receptor	Insulin receptor Insulin-1	P01322 P15127	Ins-1 Ins1 Insr	Rattus norvegicus (Norway rat)
Relaxin receptors	Insulin-like 3 Prorelaxin 1 Relaxin family peptide receptor 2 Relaxin receptor 1 Relaxin-3	A0A8I5ZRR3 P01347 Q6R6I6 Q8BFS3 Q9WUK0	Insl3 Insl7 Lgr7 Rlf Rln Rln1 Rln3 Rxfp1 Rxfp2	Rattus norvegicus (Norway rat)
TP53 Regulates Transcription of Death Receptors and Ligands	Insulin-like growth factor-binding protein 3 Transmembrane protein 219	A0A8I6AHK8 P15473	Igfbp-3 Igfbp3 Tmem219	Rattus norvegicus (Norway rat)
Laminin interactions	Integrin alpha 3 variant B Integrin alpha-7 Integrin beta-1 Integrin beta-4 Integrin subunit alpha 6 Laminin subunit alpha 4 Multiple epidermal growth factor-like domains protein 6 Nidogen-2	A0A8I6AJE9 B5DFC9 F1LTF8 I4DUB5 O88281 P49134 Q63258 Q64632	Egfl3 ITGA3B Itga3 Itga6 Itga7 Itgb1 Itgb4 Lama4 Megf6 Nid2	Rattus norvegicus (Norway rat)
GPER1 signaling	Integrin beta-1 Integrin subunit alpha 5 SHC-transforming protein 1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A0A0G2K1E2 P09456 P12368 P12369 P27791 P49134 P68182 P81377 Q5M824	Itga5 Itgb1 Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b Shc1	Rattus norvegicus (Norway rat)
Regulation of IFNA/IFNB signaling	Interferon 1ai1 Interferon 1ai2 Interferon 1ai3 Interferon alpha and beta receptor subunit 1 Interferon alpha and beta receptor subunit 2 Interferon alpha-1-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-12-like Interferon alpha-1 Interferon beta Signal transducer and activator of transcription 4 Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6 Uncharacterized protein ubiquitinyl hydrolase 1	A0A0G2JX93 A0A7R8C3L7 A0A8I5ZN08 A0A8I5ZQR5 A0A8I6A4N8 A0A8I6AEQ7 A0A8I6AM23 A0A8I6AN84 A0A8I6ANZ6 A0A8I6GMD9 D3Z919 D3ZD03 D3ZDS9 D3ZFH0 F7EYG9 M0R8H7 P05011 P20417 P41499 P70499 P81718 Q6AYC7	ENSRNOG00000065554 If1ai1 If1ai2 If1ai3 Ifna1 Ifna12l Ifna4 Ifna4l1 Ifnar1 Ifnar2 Ifnb Ifnb1 Jak1 LOC100911527 LOC120103158 LOC120103159 LOC120103160 LOC120103161 LOC120103162 LOC120103163 LOC120103164 Ptph6 Ptpn1 Ptpn11 Ptpn6 RGD1560539 Stat1 Stat2 Stat4 Tyk2 Usp18	Rattus norvegicus (Norway rat)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A8I6AM23 D4A109 F7FHZ1 P01581 P11345 P21708 P63086 Q62689	Erk1 Erk2 Ifng Ifngr1 Ifngr2 Jak1 Jak2 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Raf Raf1	Rattus norvegicus (Norway rat)
Regulation of IFNG signaling	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Protein inhibitor of activated STAT, 1 Signal transducer and activator of transcription 4 Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 2	A0A0G2JX93 A0A8I6AJT7 A0A8I6AM23 D4A109 F7FHZ1 O88583 P01581 P35233 Q5I0H3 Q62689 Q9QX78	Cish3 Ifng Ifngr1 Ifngr2 Jak1 Jak2 Pias1 Ptpn2 Socs1 Socs3 Stat1 Stat4 Sumo1	Rattus norvegicus (Norway rat)
Interleukin-20 family signaling	Interferon, lambda 1 Interferon, lambda 3 Interferon, lambda receptor 1 Interleukin 10 receptor subunit beta Interleukin 20 receptor subunit alpha Interleukin 20 receptor subunit beta Interleukin 22 receptor subunit alpha 1 Interleukin 22 Interleukin family protein Interleukin family protein Interleukin-22 receptor subunit alpha-2 Interleukin-24 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11	A0A0G2JWM7 A0A0G2JX93 A0A8I5ZW17 A0A8I6A0L8 A0A8I6AM23 D3ZB58 D3ZD03 D3ZFI7 D3ZJZ2 D3ZM36 D4A2T8 F1M3K4 F7EYG9 G3V6X6 P41499 P52631 P52632 Q62689 Q62771 Q63272 Q7TNI4 Q9JI24	If2d Ifnl1 Ifnl3 Ifnlr1 Il10rb Il19 Il20 Il20ra Il20rb Il22 Il22ra1 Il22ra2 Il24 Il28b Il28ra Jak1 Jak2 Jak3 Mgf Mob5 Ptpn11 Stat1 Stat2 Stat3 Stat4 Stat5a Stat5b Tyk2	Rattus norvegicus (Norway rat)
Receptor-type tyrosine-protein phosphatases	Interleukin 1 receptor accessory protein-like 2 Interleukin-1 receptor accessory protein-like 1 Interleukin-1 receptor accessory protein Leucine-rich repeat-containing protein 4B Liprin-alpha-3 Liprin-alpha-4 (Fragment) NT-3 growth factor receptor PPFIA binding protein 1 PPFIA binding protein 2 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Receptor-type tyrosine-protein phosphatase F Receptor-type tyrosine-protein phosphatase S SLIT and NTRK-like family, member 1 SLIT and NTRK-like family, member 2 SLIT and NTRK-like family, member 3 SLIT and NTRK-like family, member 4 SLIT and NTRK-like family, member 5 SLIT and NTRK-like family, member 6 protein-tyrosine-phosphatase	A0A1B0GWS0 A0A1W2Q6G2 A0A8I5ZVX1 A0A8I6A6R5 A0A8I6AET5 A0A8I6AK94 A0A8I6ANB2 D3Z8D8 D3ZK41 D3ZP44 D4A062 M0R9U3 P0CC10 P59824 Q03351 Q63621 Q64604 Q64605 Q91Z79 Q91Z80	Il1rap Il1rapl1 Il1rapl2 Lar Lrig4 Lrrc4b Ntrk3 Ppfia1 Ppfia2 Ppfia3 Ppfia4 Ppfibp1 Ppfibp2 Ptprd Ptprf Ptprs Slitrk1 Slitrk2 Slitrk3 Slitrk4 Slitrk5 Slitrk6 Trkc	Rattus norvegicus (Norway rat)
Interleukin-10 signaling	Interleukin 10 receptor subunit alpha Interleukin 10 receptor subunit beta Interleukin-10 Signal transducer and activator of transcription 3 Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I6AM23 D3ZD03 D3ZM36 G3V830 P29456 P52631	Il-10 Il10 Il10ra Il10rb Jak1 Stat3 Tyk2	Rattus norvegicus (Norway rat)
Interleukin-12 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-12 subunit beta Protein disulfide-isomerase Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Vesicle-associated membrane protein 7	A0A8I6AM23 D3ZD03 E9PSU7 E9PU71 F1LRH7 P04785 Q62689 Q9JHW5 Q9R103	IL12B Il12a Il12b Il12rb1 Il12rb2 Jak1 Jak2 P4hb Pdia1 Sybl1 Tyk2 Vamp7	Rattus norvegicus (Norway rat)
Interleukin-23 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 23 receptor Interleukin-12 subunit beta Interleukin-23 subunit alpha Protein disulfide-isomerase Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	D3ZD03 E9PSU7 E9PU71 F1LX96 P04785 P52631 Q62689 Q91Z84	IL12B Il12b Il12rb1 Il23a Il23r Jak2 P4hb Pdia1 Stat3 Tyk2	Rattus norvegicus (Norway rat)
Interleukin-21 signaling	Interleukin 21 receptor Interleukin-21 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase	A0A0G2JX93 A0A8I5ZRF2 A0A8I6AM23 A3QPB9 P52631 P52632 Q62771 Q63272	Il21 Il21r Jak1 Jak3 Mgf Stat1 Stat3 Stat4 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Interleukin-36 pathway	Interleukin 36, beta Interleukin 36, gamma Interleukin-1 receptor accessory protein Interleukin-1 receptor-like 2 Interleukin-1 Interleukin-1 Interleukin-1	A0A8I6AH64 D4A1A6 D4A1I2 D4A9I5 F7FNC4 Q62929 Q63621	Il1f10 Il1rap Il1rl2 Il36a Il36b Il36g Il36rn	Rattus norvegicus (Norway rat)
Interleukin-9 signaling	Interleukin 9 receptor Interleukin 9 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase	A0A0G2JX93 A0A8I6AHK3 A0A8I6AM23 D4A8I9 P52631 P52632 Q62771 Q63272	Il9 Il9r Jak1 Jak3 Mgf Stat1 Stat3 Stat4 Stat5a Stat5b	Rattus norvegicus (Norway rat)
Interleukin-33 signaling	Interleukin-1 receptor accessory protein Interleukin-1 receptor-like 1 Interleukin-33	Q62611 Q63621 Q66H70	Fit1 Il1rap Il1rl1 Il33	Rattus norvegicus (Norway rat)
Interleukin-38 signaling	Interleukin-1 receptor accessory protein-like 1 Interleukin-1 receptor-like 2 Interleukin-1 Mitogen-activated protein kinase 8	D4A9I5 P49185 P59824 Q62929	Il1f10 Il1rapl1 Il1rl2 Jnk1 Mapk8 Prkm8	Rattus norvegicus (Norway rat)
TRAF6-mediated induction of TAK1 complex within TLR4 complex	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 D3ZUM2 D3ZXR7 M0RA08 P0C8E4 P0CG51 P62982 Q4QQS0 Q56DL5 Q5U303 Q63429 Q63691 Q9QX05	Cd14 Irak2 LOC100360645 Ly96 Map3k7 Map3k7ip2 Plin3 Rps27a Sarm1 Tab1 Tab2 Tab3 Ticam1 Ticam2 Tlr4 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 D3ZXR7 M0RA08 P0C8E4 P0CG51 P62982 Q4QQS0 Q56DL5 Q5U303 Q63429 Q63691 Q9QX05	Cd14 Irak2 LOC100360645 Ly96 Map3k7 Map3k7ip2 Plin3 Rps27a Tab1 Tab2 Tab3 Ticam1 Ticam2 Tlr4 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
activated TAK1 mediates p38 MAPK activation	Interleukin-1 receptor-associated kinase-like 2 MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mapk11 protein Mitogen-activated protein kinase 14 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleotide-binding oligomerization domain containing 1 Nucleotide-binding oligomerization domain containing 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 variant 1 mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase non-specific serine/threonine protein kinase	A0A0G2JYX9 A0A0G2K4Z7 A0A0U1RRU5 A0A8I6A3Q1 A0A8I6ABN5 A0A8I6AH74 B5DF45 D4A3U7 D4ADT7 G3V783 M0R7E7 P0C8E4 P70618 Q4QQS0 Q5U303 Q66H84 Q6TMG5 Q80ZF4 Q925D6	Csbp1 Csbp2 ENSRNOG00000067007 Ikbkg Irak1 Irak2 Map2k3 Map2k6 Map3k7 Map3k7ip2 Mapk11 Mapk14 Mapkapk2 Mapkapk3 Mkk6 Nemo Nod1 Nod2 Ripk2 Tab1 Tab2 Tab3 Traf6	Rattus norvegicus (Norway rat)
IRAK2 mediated activation of TAK1 complex	Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 P0C8E4 P0CG51 P62982 Q4QQS0 Q5U303 Q63429	Irak2 LOC100360645 Map3k7 Map3k7ip2 Rps27a Tab1 Tab2 Tab3 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Interleukin-2 signaling	Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Protein-tyrosine kinase 2-beta Proto-oncogene tyrosine-protein kinase LCK SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK3 Tyrosine-protein kinase SYK Tyrosine-protein kinase	A0A8I6AM23 P17108 P26896 P26897 P52632 P70600 Q01621 Q5M824 Q62771 Q63272 Q64725	Fak2 Il-2 Il2 Il2ra Il2rb Jak1 Jak3 Lck Mgf Ptk2b Pyk2 Shc1 Stat5a Stat5b Syk	Rattus norvegicus (Norway rat)

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