GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Activation of G protein gated Potassium channels	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 O88871 P43425 P48548 P48550 P49655 P52188 P52190 P52191 P52287 P54311 P54313 P61954 P62882 P63077 P63219 P63251 Q63511 Q64273 Q91ZF1 Q9Z0U4	Gabbr1 Gabbr2 Girk1 Girk2 Girk3 Girk4 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Gpr51 Irk1 Irk2 Irk3 Kab-2 Kcnj10 Kcnj12 Kcnj15 Kcnj16 Kcnj2 Kcnj3 Kcnj4 Kcnj5 Kcnj6 Kcnj7 Kcnj9 Kga	Rattus norvegicus (Norway rat)
Regulation of FZD by ubiquitination	Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-8 Leucine-rich repeat-containing G protein-coupled receptor 6 Leucine-rich repeat-containing G-protein coupled receptor 5 Low-density lipoprotein receptor-related protein Low-density lipoprotein receptor-related protein Polyubiquitin-B Polyubiquitin-C Protein Wnt R-spondin 1 R-spondin 2 R-spondin 3 R-spondin 4 RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A0G2K0H3 A0A8I5ZKZ0 A0A8I6A5Y3 A0A8I6AML0 A0A8I6G721 A7LKE6 D3ZBD1 D3ZJU9 D3ZN39 D4AC13 D4ACX0 F1M077 G3V6L1 I7GAZ6 P0CG51 P62982 Q498S8 Q63429 Q8CHL0 Q9QZH0	Fzd4 Fzd5 Fzd6 Fzd8 LOC100360645 Lgr5 Lgr6 Lrp5 Lrp6 R-spondin2 Rnf43 Rps27a Rspo1 Rspo2 Rspo3 Rspo4 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Usp8 Wnt3a Znrf3	Rattus norvegicus (Norway rat)
Nephrin family interactions	Cytoplasmic protein Cytoplasmic protein IQ motif containing GTPase activating protein 1 Kin of IRRE-like protein 1 Kirre like nephrin family adhesion molecule 2 Kirre like nephrin family adhesion molecule 3 Nephrin Tyrosine-protein kinase Fyn	A0A8I5ZQV3 B2RZ33 D4A3M8 D4A934 G3V7Q7 Q62844 Q6X936 Q9R044	Fyn Iqgap1 Kirrel Kirrel1 Kirrel2 Kirrel3 Nck1 Nck2 Neph1 Nphn Nphs1	Rattus norvegicus (Norway rat)
PECAM1 interactions	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Integrin beta-3 Integrin subunit alpha V Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Platelet endothelial cell adhesion molecule Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	F1LM93 F1LZX9 P10686 P41499 P81718 P97573 Q01621 Q07014 Q3SWT0 Q62844 Q8R2H2 Q9WUD9	Fyn Inpp5d Itgav Itgb3 Lck Lyn Pecam Pecam1 Plcg1 Ptph6 Ptpn11 Ptpn6 Ship Ship1 Src Yes1	Rattus norvegicus (Norway rat)
NGF processing	Beta-nerve growth factor Furin Proprotein convertase subtilisin/kexin type 5 Proprotein convertase subtilisin/kexin type 6	P23377 P25427 P41413 Q63415	Fur Furin Ngf Ngfb Pace4 Pcsk3 Pcsk5 Pcsk6	Rattus norvegicus (Norway rat)
Extracellular matrix organization	Fibronectin	P04937	Fn1	Rattus norvegicus (Norway rat)
Antagonism of Activin by Follistatin	Follistatin-related protein 3 Follistatin Inhibin beta A chain Inhibin beta B chain	P17491 P18331 P21674 Q99PW7	Flrg Fst Fstl3 Inhba Inhbb	Rattus norvegicus (Norway rat)
GP1b-IX-V activation signalling	14-3-3 protein zeta/delta Filamin A Glycoprotein 9 Glycoprotein Ib platelet subunit alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Platelet glycoprotein Ib beta chain Platelet glycoprotein V Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase	A0A8I5ZV49 D3ZQU7 O08770 P11345 P63102 Q4AEG0 Q63787 Q9JJM7 Q9WUD9	Flna Gp1ba Gp1bb Gp5 Gp9 Msfs1 Pik3r1 Raf Raf1 Src Ywhaz	Rattus norvegicus (Norway rat)
VEGFR2 mediated cell proliferation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3-phosphoinositide-dependent protein kinase 1 GTPase HRas GTPase KRas GTPase NRas Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C zeta type Proto-oncogene tyrosine-protein kinase Src Ras GTPase-activating protein 1 Sphingosine kinase 1 Vascular endothelial growth factor A Vascular endothelial growth factor receptor 2	O08775 O55173 P05696 P08644 P09215 P09217 P10686 P16612 P20171 P50904 P68403 Q04970 Q91V26 Q9WUD9	Flk1 Hras Hras1 Kdr Kras Kras2 Nras Pdk1 Pdpk1 Pkca Pkcb Pkcd Pkcz Plcg1 Prkca Prkcb Prkcb1 Prkcd Prkcz Rasa Rasa1 Sphk1 Src Vegf Vegfa	Rattus norvegicus (Norway rat)
Neurophilin interactions with VEGF and VEGFR	Neuropilin-1 Neuropilin-2 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2	O08775 O35276 P53767 Q9QWJ9	Flk1 Flt-1 Flt1 Kdr Nrp1 Nrp2 Vegfr1	Rattus norvegicus (Norway rat)
FOXO-mediated transcription of cell cycle genes	Forkhead box O3 Forkhead box O4 Forkhead box protein G1 Forkhead box protein O1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4	D3ZBQ1 D4A433 G3V7R4 O70436 O70437 P84025 Q00939	Fkhl1 Foxg1 Foxg1b Foxo1 Foxo1a Foxo3 Foxo4 Madh2 Madh3 Madh4 Smad2 Smad3 Smad4	Rattus norvegicus (Norway rat)
Interleukin-33 signaling	Interleukin-1 receptor accessory protein Interleukin-1 receptor-like 1 Interleukin-33	Q62611 Q63621 Q66H70	Fit1 Il1rap Il1rl1 Il33	Rattus norvegicus (Norway rat)
VEGF ligand-receptor interactions	Placenta growth factor Vascular endothelial growth factor A Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D	O35251 O35485 O35757 P16612 Q63434	Figf Pgf Plgf Vegf Vegfa Vegfb Vegfc Vegfd Vrf	Rattus norvegicus (Norway rat)
VEGF binds to VEGFR leading to receptor dimerization	Placenta growth factor Vascular endothelial growth factor A Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2 Vascular endothelial growth factor receptor 3	O08775 O35251 O35485 O35757 P16612 P53767 Q63434 Q91ZT1	Figf Flk1 Flt-1 Flt-4 Flt1 Flt4 Kdr Pgf Plgf Vegf Vegfa Vegfb Vegfc Vegfd Vegfr1 Vegfr3 Vrf	Rattus norvegicus (Norway rat)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor 1 Klotho	Q04589 Q8VI82 Q9Z2Y9	Fgf23 Fgfr1 Flg Kl	Rattus norvegicus (Norway rat)
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B1 Sodium/glucose cotransporter 1 Sodium/glucose cotransporter 2 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 2, facilitated glucose transporter member 7 Solute carrier family 2, facilitated glucose transporter member 8 Solute carrier family 45, member 3 Solute carrier family 5 member 4 Solute carrier family 5 member 9 Sugar transporter SWEET1	A0A0G2JY02 A0A8I6AVN8 A4ZYQ5 D3ZH22 D3ZIS0 D3ZNG4 D3ZPP5 D3ZVY8 F1LTM4 F7FG05 G3V8X5 P11167 P12336 P19357 P53790 P53792 Q07647 Q9JJZ1	Fgf21 GLUT7 Glut1 Glut2 Glut3 Glut4 Glut8 Glutx1 Mfsd4b Mfsd4b1 RGD1559971 RGD1561777 Rag1ap1 Rga Sglt1 Sglt2 Slc2a1 Slc2a10 Slc2a12 Slc2a2 Slc2a3 Slc2a4 Slc2a7 Slc2a8 Slc2a9 Slc45a3 Slc50a1 Slc5a1 Slc5a10 Slc5a2 Slc5a4 Slc5a9	Rattus norvegicus (Norway rat)	G58161NS G70323CJ
Syndecan interactions	Aa1018 Fibroblast growth factor 2 Integrin beta-1 Integrin beta-3 Integrin beta-4 Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 6 Integrin subunit alpha V Protein kinase C alpha type Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Transforming growth factor beta-1 proprotein	A0A0G2K470 A0A8I6AJE9 A0A8I6AQL1 F1LZX9 P05696 P13109 P17246 P26260 P33671 P34900 P34901 P49134 Q64632 Q7TQ11 Q8R2H2	Fgf-2 Fgf2 Hspg1 Itga2 Itga6 Itgav Itgb1 Itgb3 Itgb4 Itgb5 Pkca Prkca Sdc1 Sdc2 Sdc3 Sdc4 Synd1 Synd2 Synd3 Synd4 Tgfb1 Vtn	Rattus norvegicus (Norway rat)
FGFR3b ligand binding and activation	Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor	A0A0G2K210 A0A8I6B5D5 O88182 P36364 P61149 P63076 Q9EST9	Fgf-1 Fgf-9 Fgf1 Fgf17 Fgf18 Fgf20 Fgf8 Fgf9 Fgfa Fgfr3	Rattus norvegicus (Norway rat)
FGFR3c ligand binding and activation	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor	A0A0G2K210 A0A8I6B5D5 F1LSQ8 O54769 O88182 P13109 P36364 P48807 P61149 P63076 Q8VI82 Q9EST9	Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3	Rattus norvegicus (Norway rat)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor	A0A0G2K210 A0A8I6B5D5 F1LSQ8 O54769 O88182 P10686 P13109 P36364 P48807 P61149 P63076 Q8VI82 Q9EST9	Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3 Plcg1	Rattus norvegicus (Norway rat)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Free fatty acid receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha	A0A8J8XRQ3 O88302 O89040 P10687 P82471 Q8K3T4 Q99JE6 Q9JID2	Ffar1 Gna11 Gna14 Gna15 Gnaq Gpr40 Plcb1 Plcb2 Plcb3	Rattus norvegicus (Norway rat)
Free fatty acid receptors	Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3	B2GV46 Q76EI6 Q8K3T4	Ffar1 Ffar2 Ffar3 Gpr40 Gpr41 Gpr43	Rattus norvegicus (Norway rat)
Sema3A PAK dependent Axon repulsion	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin A1 Plexin A2 Plexin A4 Plexin-A3 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase	A0A8I6AGW9 D3ZES7 D3ZPX4 D3ZWP6 D4A584 P34058 P35465 P53669 P82995 Q62829 Q62844 Q63548 Q64303 Q6RUV5 Q9QWJ9	Fes Fyn Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Limk Limk1 Nrp1 Pak1 Pak2 Pak3 Plxna1 Plxna2 Plxna3 Plxna4 Plxna4a Rac Rac1 Sema3a	Rattus norvegicus (Norway rat)
GDP-fucose biosynthesis	Fucose kinase Fucose-1-phosphate guanylyltransferase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase L-fucose mutarotase Solute carrier family 35 member C1	A0A0G2JVI4 A0A0G2K0C0 A0A8I5ZPV8 D3ZWW0 D4ACG8 G3V762	Fcsk Fpgt Fuk Fuom Gfus Gmds Slc35c1 Tsta3	Rattus norvegicus (Norway rat)	G85196CF G96881BQ
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	FERM, ARH/RhoGEF and pleckstrin domain protein 2 Neuropilin-1 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Plexin A1 Plexin A2 Plexin A4 Plexin-A3 Semaphorin-3A Talin 1 Tyrosine-protein kinase Fyn	A0A8I6ABG6 A0A8I6AGW9 D3ZES7 D3ZFK8 D3ZPX4 D3ZWP6 Q5I6B8 Q62844 Q63548 Q9QWJ9	Farp2 Fyn Nrp1 Pip5k1c Plxna1 Plxna2 Plxna3 Plxna4 Plxna4a Sema3a Tln1	Rattus norvegicus (Norway rat)

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