GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
RAS processing	ADP-ribosylation factor-like protein 2 Acyl-protein thioesterase 1 Alpha/beta hydrolase domain-containing protein 17A Alpha/beta hydrolase domain-containing protein 17B Alpha/beta hydrolase domain-containing protein 17C Bcl-2-like protein 1 CAAX prenyl protease 2 Calmodulin-3 GTPase HRas GTPase KRas GTPase NRas Golgin subfamily A member 7 Palmitoyltransferase Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C theta type Protein-S-isoprenylcysteine O-methyltransferase Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase cGMP-dependent protein kinase 2	A0A8I5ZMP6 A0A8I5ZS01 A0A8I6AGE4 A0A8I6AMA7 B0BMW8 B5DFK7 D3ZRD3 F7F533 O08697 P08644 P0DP31 P20171 P53563 P70470 Q02293 Q04631 Q04970 Q5XIJ5 Q64595 Q6AY17 Q6AYQ1 Q9WTQ0 Q9WVM4	Abhd17a Abhd17b Abhd17c Apt1 Arl184 Arl2 Bcl2l1 Bclx Blc2l CaMIII Calm3 Cam3 Camc ENSRNOG00000064803 ENSRNOG00000067432 Fnta Fntb Golga7 Hras Hras1 Icmt Kras Kras2 LOC100910107 LOC120097921 LOC120098474 Lypla1 Nras Pde6d Pkcq Prkcq Prkg2 Rce1 Usp17l Usp17l8 Usp17la Usp17la2 Usp17lh Usp17li Zdhhc9	Rattus norvegicus (Norway rat)
Synthesis of PC	Abhydrolase domain containing 3, phospholipase Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Choline O-acetyltransferase Choline kinase alpha Choline transporter-like protein 1 Choline transporter-like protein 2 Choline transporter-like protein 3 Choline transporter-like protein 4 Choline transporter-like protein Choline-phosphate cytidylyltransferase A Choline-phosphate cytidylyltransferase B Choline/ethanolamine kinase Choline/ethanolaminephosphotransferase 1 Cholinephosphotransferase 1 Lysophosphatidylcholine acyltransferase 1 MFSD2 lysolipid transporter A, lysophospholipid Phosphatidylcholine transfer protein Phosphatidylethanolamine N-methyltransferase Phosphoethanolamine/phosphocholine phosphatase 1 StAR-related lipid transfer domain containing 10 StAR-related lipid transfer domain containing 7 phosphatidate phosphatase phosphatidate phosphatase phosphatidate phosphatase	A0A0G2JW03 A0A0G2JY62 A0A0G2KB11 A0A8I5ZLE8 A0A8I6ATX5 A0A8I6AUU1 B1WBW6 B4F795 D4A3D4 F7FH41 G3V6P4 O54783 P19139 P19836 P32738 P53809 P67874 Q01134 Q08388 Q1HAQ0 Q66H21 Q6AXM5 Q6AY92 Q6MG71 Q8VII6 Q9QZC4	Abhd3 Aytl2 Cctb Cd92 Cdw92 Cept1 Chat Chetk Chk Chka Chkb Chkl Chpt1 Ck2n Ckr Cpt1 Csnk2a1 Csnk2a2 Csnk2b Ctl1 Ctl2 Ctl3 Ctl4 Ctpct Lpcat1 Lpin1 Lpin2 Lpin3 Mfsd2a Ng22 Pctp Pcyt1 Pcyt1a Pcyt1b Pempt Pemt Phospho1 Slc44a1 Slc44a2 Slc44a3 Slc44a4 Slc44a5 Stard10 Stard2 Stard7 TPPT1	Rattus norvegicus (Norway rat)
RHO GTPases Activate WASPs and WAVEs	Abl interactor 1 Abl-interactor 2 Actin related protein 2/3 complex, subunit 3 Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 BAR/IMD domain-containing adapter protein 2 BRICK1 subunit of SCAR/WAVE actin nucleating complex Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein Cytoplasmic protein Focal adhesion kinase 1 Growth factor receptor-bound protein 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NCK associated protein 1 like NCK interacting protein with SH3 domain Nck-associated protein 1 Ras-related C3 botulinum toxin substrate 1 Tyrosine-protein kinase Tyrosine-protein kinase WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 3 Wiskott-Aldrich syndrome protein family member Wiskott-Aldrich syndrome protein family member	A0A0G2K6M9 A0A8I5Y5E8 A0A8I5ZLD3 A0A8I6AH32 A0A8I6AHL8 A0A8I6AL89 B2RZ33 D3ZUP5 D3ZWX4 D4A8H8 E9PT20 M0R7F3 O35346 O88656 P21708 P55161 P60711 P62994 P63086 P63259 P85970 Q4KLF8 Q4V7C7 Q5BJU7 Q5FWU0 Q5M7U6 Q6GMN2 Q6IN36 Q6RUV5 Q8CFN2 Q99PD4 Q9QZM5 Q9Z0G8	Abi1 Abi2 Abl1 Actb Actg Actg1 Actr2 Actr3 Arp2 Arp3 Arpc1a Arpc1b Arpc2 Arpc3 Arpc4 Arpc5 Ash Baiap2 Brk1 Btk Cdc42 Cr16 Cyfip1 Cyfip2 Erk1 Erk2 Fak Fak1 Grb2 Hem2 Mapk Mapk1 Mapk3 Nap1 Nck1 Nckap1 Nckap1l Nckipsd Prkm1 Prkm3 Ptk2 Rac Rac1 Wasf1 Wasf2 Wasf3 Waspip Wave1 Wip Wipf1 Wipf3	Rattus norvegicus (Norway rat)
VEGFA-VEGFR2 Pathway	Abl interactor 1 Abl-interactor 2 Actin-binding protein WASF1 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 BRICK1 subunit of SCAR/WAVE actin nucleating complex Breast cancer anti-estrogen resistance protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein Cytoplasmic protein Cytoplasmic protein Engulfment and cell motility 1 Engulfment and cell motility 2 Focal adhesion kinase 1 Heat shock protein HSP 90-alpha Heat shock protein beta-1 Integrin beta-3 Integrin subunit alpha V MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mapk11 protein Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 NCK associated protein 1 like Nck-associated protein 1 Neutrophil cytosol factor 2 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 4 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Protein-tyrosine kinase 2-beta Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 SH2 domain containing 2A SH2 domain containing adaptor protein B SHC-transforming protein 2 Serine/threonine-protein kinase PAK 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Vascular endothelial growth factor A Vascular endothelial growth factor receptor 2 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Wiskott-Aldrich syndrome protein family member Wiskott-Aldrich syndrome protein family member cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta receptor protein-tyrosine kinase	A0A0G2K344 A0A8I5ZLD3 A0A8I5ZNF3 A0A8I5ZPB5 A0A8I6AH32 A0A8I6AHL8 A7E3N2 B2RZ33 D3ZN31 D3ZUP5 D3ZY46 D3ZYG0 D4A3M8 D4A3U7 D4A8H8 E9PSY0 F1LZX9 F1M707 G3V982 M0R7F3 O08775 O35346 O70142 P16612 P27791 P42930 P54100 P55161 P61589 P68182 P70600 P70618 P82995 Q5BJU7 Q5FWU0 Q5I0Q2 Q62737 Q62844 Q62868 Q63538 Q63644 Q63767 Q63768 Q63787 Q63788 Q64303 Q66H76 Q66H84 Q6GMN2 Q6RUV5 Q80ZF4 Q8CFN2 Q8R2H2 Q9ERL1 Q9QZM5 Q9WTY9 Q9WUD9 Q9Z1L0	Abi1 Abi2 Arha Arha2 Axl Baiap2 Bcar1 Brk1 Cas Cdc42 Crk Crkas Crko Csbp1 Csbp2 Cyba Cybb Cyfip1 Cyfip2 Elmo1 Elmo2 Fak Fak1 Fak2 Flk1 Fyn Hem2 Hsp27 Hsp86 Hsp90aa1 Hspb1 Hspca Itgav Itgb3 Kdr Mapk11 Mapk12 Mapk13 Mapk14 Mapkapk2 Mapkapk3 Nap1 Ncf1 Ncf2 Ncf4 Nck1 Nck2 Nckap1 Nckap1l Pak2 Pik3ca Pik3cb Pik3r1 Pik3r2 Pkacb Prkaca Prkacb Ptk2 Ptk2b Pxn Pyk2 Rac Rac1 Rhoa Rock1 Rock2 Sapk3 Sck Sh2d2a Shb Shc2 Src Vav Vav1 Vav2 Vav3 Vegf Vegfa Wasf1 Wasf2 Wasf3 Wave1	Rattus norvegicus (Norway rat)
RUNX1 regulates transcription of genes involved in differentiation of HSCs	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CDK-activating kinase assembly factor MAT1 Core-binding factor subunit beta Cyclin-H Cyclin-dependent kinase 7 (Fragment) E3 ubiquitin-protein ligase Endothelial transcription factor GATA-2 Erythroid transcription factor Histone-lysine N-methyltransferase LIM domain binding 1 LIM domain only protein 3 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Rhombotin-2 Runt-related transcription factor 1 TAL bHLH transcription factor 1, erythroid differentiation factor Transcription factor 12 Transcription factor E2-alpha Transcriptional coactivator YAP1 Tumor protein p73 Tyrosine-protein kinase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2K1M1 A0A0G2K3R4 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZZU1 A0A8I6A5Y3 A0A8I6G409 A0A8I6GMB2 B0BN93 D4AA88 E9PT20 F1LMQ3 F1LMZ8 F1M0L3 F1M6I7 F7EX11 F7FGV7 G3V6W6 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P21677 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P43429 P48004 P51514 P51952 P60901 P62193 P62198 P62982 Q2EJA0 Q4FZT9 Q4KM35 Q4V8E2 Q5XIC6 Q5XIU5 Q63046 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q924Y4 Q99MB5 Q9JHW0 Q9R1A0 Q9WTV5 Q9Z2X3	Abl1 Aml1 Cak Cak1 Cbfa2 Cbfb Ccnh Cdk7 Gata1 Gata2 Itch Kmt2a LOC100360645 LOC100360846 LOC100365869 Ldb1 Lmo2 Lmo3 Lmp10 Lmp2 Mecl1 Mll Mll1 Mnat1 Mo15 Mss1 Pan Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ptf1c Ring12 Rps27a Runx1 Sug1 Tal1 Tbp1 Tbp7 Tcf12 Tcf3 Tcfe2a Tp73 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Yap Yap1 Yap65	Rattus norvegicus (Norway rat)
Myogenesis	BCL2 interacting protein 2 BOC cell adhesion associated, oncogene regulated Cadherin 15 Cadherin-2 Catenin alpha-2 Catenin beta-1 Cell adhesion molecule-related/down-regulated by oncogenes Cell division control protein 42 homolog Mapk11 protein Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 14 Myoblast determination protein 1 Myocyte enhancer factor 2B Myocyte-specific enhancer factor 2A Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D Myogenic factor 6 Myogenic factor Myogenin Sperm associated antigen 9 Transcription factor 12 Transcription factor 4 Transcription factor E2-alpha Tyrosine-protein kinase	A0A096MJY4 A0A0G2JYF7 A0A0G2K1P3 A0A0G2K6E8 A0A8I6AM66 D3ZVU3 D4A0Z7 D4A3U7 E9PT20 F7EZT3 O35158 O89038 P19335 P20428 P21677 P51514 P70618 Q02346 Q2MJT0 Q62655 Q63538 Q8CFN2 Q9WU82 Q9Z1Y3	Abl1 Bnip2 Boc Catnb Cdc42 Cdh15 Cdh2 Cdo Cdon Csbp1 Csbp2 Ctnna2 Ctnnb1 Itf2 Mapk11 Mapk12 Mapk14 Mef2a Mef2b Mef2c Mef2d Mrf4 Myf5 Myf6 Myod Myod1 Myog Pan Ptf1c Sapk3 Sef2 Spag9 Tcf12 Tcf3 Tcf4 Tcfe2a	Rattus norvegicus (Norway rat)
Cyclin D associated events in G1	CDK-activating kinase assembly factor MAT1 Cullin 1 Cyclin E2 Cyclin dependent kinase inhibitor 2D Cyclin-H Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase 7 (Fragment) Cyclin-dependent kinase inhibitor 1A Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 1C Cyclin-dependent kinases regulatory subunit E2F transcription factor 2 E2F transcription factor 3 E2F transcription factor 4 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 G1/S-specific cyclin-E1 LOC682033 protein Polyubiquitin-B Polyubiquitin-C Protein phosphatase 2 scaffold subunit A alpha Proto-oncogene tyrosine-protein kinase Src Retinoblastoma-associated protein Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 S-phase kinase associated protein 2 S-phase kinase-associated protein 1 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Transcription factor E2F1 Transcription factor E2F5 (Fragment) Transcription factor Transcription factor Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase Tyrosine-protein kinase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JXE8 A0A0G2K0V6 A0A8I5Y0H0 A0A8I5ZZ18 A0A8I6A5Y3 A0A8I6AMP0 B1WBU2 B2RZ99 D3ZDS3 D3ZQ41 D3ZS28 D4A9V4 E9PT20 F1MA87 F7EX11 G3V8H9 M0RDX6 O08769 O09139 O55081 P0CG51 P33568 P35426 P36876 P39948 P39949 P48961 P51952 P55272 P62716 P62982 P63331 Q04827 Q07014 Q4QQT4 Q5XI34 Q62689 Q62814 Q63429 Q63699 Q69DC1 Q6P4Z7 Q6PEC4 Q9R1A0 Q9WUD9	Abl1 Cak Cak1 Ccnd1 Ccnd2 Ccnd3 Ccne Ccne1 Ccne2 Ccnh Cdk2 Cdk4 Cdk6 Cdk7 Cdkn1a Cdkn1b Cdkn1c Cdkn2 Cdkn2b Cdkn2d Cks1b Cks1l Cul1 E2f1 E2f2 E2f3 E2f4 E2f5 Ink4 Jak2 LOC100360645 LOC682033 LOC684111 Lyn MGC112830 Mnat1 Mo15 Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r2a Ppp2r3b Ptk6 RGD1561797 Rb-1 Rb1 Rbl1 Rbl2 Rps27a Skp1 Skp1a Skp2 Src Tfdp1 Tfdp2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vin-1 p27Kip1	Rattus norvegicus (Norway rat)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Histo-blood group ABO system transferase 2 Histo-blood group ABO system transferase 2	D4A7T1 Q10980 Q10984 Q8CFC4	Abo2 Fta Ftb Fut1 Fut2 Sec1	Rattus norvegicus (Norway rat)
Formation of WDR5-containing histone-modifying complexes	A-kinase anchoring protein 8 like ASH2 like histone lysine methyltransferase complex subunit Biorientation of chromosomes in cell division 1-like 1 CXXC-type zinc finger protein 1 Histone acetyltransferase KAT8 Histone acetyltransferase Histone acetyltransferase Histone-lysine N-methyltransferase Host cell factor 1 Host cell factor 2 Host cell factor C1 KAT8 regulatory NSL complex subunit 1 KAT8 regulatory NSL complex subunit 2 KAT8 regulatory NSL complex subunit 3 Lysine acetyltransferase 14 MAP3K12 binding inhibitory protein 1 Menin Microspherule protein 1 PAX-interacting protein 1 PAXIP1-associated glutamate-rich protein 1 PC4 and SFRS1-interacting protein PHD finger protein 20-like protein 1 PHD finger protein 20 Protein Dr1 RB binding protein 5, histone lysine methyltransferase complex subunit SAGA-associated factor 29 SET domain containing 1A, histone lysine methyltransferase SET domain containing 1B, histone lysine methyltransferase Transcriptional adapter 2-alpha Transcriptional adapter 3 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit WD repeat domain 82 WD repeat-containing protein 5 YEATS domain containing 2 Zinc finger, ZZ-type containing 3 [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-methyltransferase	A0A0G2K1E3 A0A0G2K6T6 A0A8I5Y222 A0A8I5ZPX3 A0A8I5ZS53 A0A8I6A4Z1 A0A8I6A524 A0A8I6AJF7 A0A8I6ANV4 D3ZC01 D3ZN95 D3ZQB7 D3ZSX6 D3ZSX8 D3ZTV7 D4ACX5 F1LRS1 F1M0L3 F7EKZ5 M0R565 M0R9X4 M0RC54 P0C606 P56558 Q3KR73 Q498M4 Q4V8F5 Q4V9H5 Q5M865 Q5RKG2 Q5U306 Q5XI06 Q5XI68 Q6AY70 Q6AYE3 Q812D1 Q9WVR8	Abp10 Ada3 Akap8l Ash2l Bod1l1 Ccdc101 Csrp2bp Cxxc1 Dr1 Hcfc1 Hcfc2 Kansl1 Kansl2 Kansl3 Kat14 Kat2a Kat2b Kat8 Kmt2a Kmt2b Kmt2c Ledgf Mbip Mcrs1 Men1 Mll Mll1 Myst1 Nsl2 Nsl3 Ogt Pagr1 Paxip1 Phf20 Phf20l1 Psip1 Rbbp5 Setd1a Setd1b Sgf29 Tada2a Tada2l Tada3 Tada3l Wdr5 Wdr82 Yeats2 Zzz3	Rattus norvegicus (Norway rat)
Cell-extracellular matrix interactions	Alpha-parvin FERM domain containing kindlin 2 Filamin A Filamin binding LIM protein 1 Filamin-C Integrin-linked protein kinase LIM and senescent cell antigen-like-containing domain protein LIM and senescent cell antigen-like-containing domain protein Parvin, beta Vasodilator-stimulated phosphoprotein	A0A0G2KAE1 A0A8I5Y6N4 A0A8I5ZV49 A0A8I6A6W3 A0A8I6G699 D3ZHA0 F7EWC1 F7FP13 Q99J82 Q9HB97	Abpl Actp Fblim1 Fermt2 Fln2 Flna Flnc ILK1 ILK2 Ilk Lims1 Lims2 Parva Parvb Vasp	Rattus norvegicus (Norway rat)
RHOB GTPase cycle	A-kinase anchor protein 13 Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Anillin, actin binding protein Breakpoint cluster region protein Caveolae-associated protein 1 Caveolin-1 Cell surface glycoprotein MUC18 Citron rho-interacting kinase DEP domain containing 1B Dishevelled associated activator of morphogenesis 1 Epithelial cell transforming 2 Flotillin-1 Flotillin-2 Guanine nucleotide exchange factor DBS IQ motif containing GTPase activating protein 3 Junction plakoglobin MCF.2 cell line derived transforming sequence Neuroepithelial cell transforming 1 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Protocadherin 7 Rac GTPase-activating protein 1 Rho GDP dissociation inhibitor gamma Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB Rhophilin-2 Rhotekin STE20-like serine/threonine-protein kinase Serine/threonine-protein kinase 10 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase N2 Sosondowah ankyrin repeat domain family member C StAR-related lipid transfer domain containing 13 StAR-related lipid transfer domain containing 8 Stomatin Synaptosomal-associated protein 23 Tight junction protein 2 Transferrin receptor protein 1 Unconventional myosin-IXa Unconventional myosin-IXb Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein 3	A0A0G2JTR4 A0A0G2JXT9 A0A0G2JYR5 A0A0G2K7N9 A0A0G2K860 A0A8I5ZRJ5 A0A8I5ZS98 A0A8I5ZV26 A0A8I5ZZT6 A0A8I5ZZX2 A0A8I6A9Q4 A0A8I6AE68 A0A8I6ALD4 A0A8I6APL5 A0A8I6AVA8 A0A8I6GDA1 A0A8I6GLR6 A0A8I6GM04 D3ZCS4 D3ZKC8 D3ZU63 D3ZUD0 D3ZYG0 D4A5B9 D4A8N7 D4AA32 E9PSL7 E9PT59 E9PTG8 F1LVW7 F1LXF1 F1M3G7 F1M775 F1MAK3 M0R3X3 M0RBM9 O08815 O08874 O70377 P0C6P5 P0CAX5 P41350 P62747 P63025 P68035 P81128 P85125 Q5FVC2 Q62868 Q63358 Q63406 Q63433 Q63644 Q63744 Q63787 Q63788 Q68HB6 Q6P0K8 Q6P720 Q6V7V2 Q99376 Q9EPF2 Q9ES67 Q9Z1E1 Q9Z1I6 Q9Z1N3 Q9Z2S9	Abr Actc Actc1 Akap13 Anln Arhb Arhgap1 Arhgap21 Arhgap26 Arhgap32 Arhgap35 Arhgap5 Arhgap7 Arhgdig Arhgef1 Arhgef10 Arhgef10l Arhgef11 Arhgef12 Arhgef17 Arhgef2 Arhgef25 Arhgef28 Arhgef3 Arhgef5 Bcr CRIK Cav Cav1 Cavin1 Cit Daam1 Depdc1b Diap1 Diaph1 Diaph3 Dlc1 Ect2 Flot1 Flot2 Geft Grlf1 Iqgap3 Jup Lsc Mcam Mcf2 Mcf2l Muc18 Myo9a Myo9b Myr5 Myr7 Net1 Ophn1 Ost P190A Pak2 Pcdh7 Pg Pik3r1 Pik3r2 Pkn Pkn1 Pkn2 Prex1 Prk1 Prk2 Prkcl1 Prkcl2 Ptrf RGD1565043 Racgap1 Reg1 Reg2 Rgnef Rhob Rhogap Rhpn2 Rock1 Rock2 Rt13 Rtkn Sk2 Slk Snap23 Sowahc Stard12 Stard13 Stard8 Stk10 Stom Syb3 Tfrc Tjp2 Trfr Vamp3 Vangl1 Vav2 p190ARHOGAP	Rattus norvegicus (Norway rat)
G alpha (12/13) signalling events	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Ephexin-1 Epithelial cell transforming 2 FYVE, RhoGEF and PH domain containing 1 FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide-binding protein subunit alpha-12 Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kalirin LOC687105 protein MCF.2 cell line derived transforming sequence Neuroepithelial cell transforming 1 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology domain-containing family G member 5 Plexin B1 Proto-oncogene vav Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein RhoB SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 TIAM Rac1 associated GEF 1 TIAM Rac1 associated GEF 2 Thromboxane A2 receptor Transforming protein RhoA Triple functional domain protein Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 non-specific serine/threonine protein kinase	A0A0G2JTR4 A0A0G2JTU0 A0A0G2JUP3 A0A0G2JXT9 A0A0G2K6M9 A0A0G2K860 A0A8I5ZMG2 A0A8I5ZPB5 A0A8I5ZZX2 A0A8I6A9Q4 A0A8I6AC12 A0A8I6AL39 A0A8I6AVA8 A0A8I6G7U0 A0A8I6GLR6 A1IGU3 B0BN40 B2GUW2 D3Z9I3 D3ZDX5 D3ZMS5 D3ZUD0 D3ZYG0 D4A1D2 D4A3T0 D4A646 D4AD85 E9PT59 F1M0Z1 F1M3G7 F1MAI3 G3V9A0 M0R3X3 M0RBM9 O55043 O88387 P15823 P23944 P34978 P43140 P54100 P61589 P62747 P97924 Q5BKC9 Q5FVC2 Q5XXR3 Q62868 Q63210 Q63406 Q63644 Q6P720 Q6Q7Y5 Q6RFZ7 Q99JE4 Q9ES67 Q9QX73 Q9WVE9 Q9Z1I6	Abr Adra1a Adra1b Adra1c Adra1d Akap13 Arha Arha2 Arhb Arhgef1 Arhgef10 Arhgef10l Arhgef11 Arhgef12 Arhgef15 Arhgef16 Arhgef17 Arhgef19 Arhgef2 Arhgef25 Arhgef26 Arhgef3 Arhgef33 Arhgef37 Arhgef38 Arhgef39 Arhgef5 Arhgef6 Arhgef7 Arhgef9 Btk Duo Ect2 Ehsh1 Fgd1 Fgd2 Fgd3 Fgd4 Geft Gna12 Gna13 Grf2 Hapip Itsn Itsn1 Kalrn LOC687105 Lsc Mcf2 Mcf2l Net1 Ngef Obscn Ost Pak3bp Pixb Plekhg2 Plekhg5 Plxnb1 Prex1 RGD1565043 Rasgrf2 Rhoa Rhob Rock1 Rock2 Rt13 Sos1 Sos2 Tbxa2r Tech Tiam1 Tiam2 Trio Vav Vav1 Vav2 Vav3	Rattus norvegicus (Norway rat)
NRAGE signals death through JNK	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Bcl-2-like protein 11 Bcl2-associated agonist of cell death Ephexin-1 Epithelial cell transforming 2 FYVE, RhoGEF and PH domain containing 1 FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kalirin LOC687105 protein MCF.2 cell line derived transforming sequence Mitogen-activated protein kinase 8 Neuroepithelial cell transforming 1 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology domain-containing family G member 5 Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 TIAM Rac1 associated GEF 1 TIAM Rac1 associated GEF 2 Triple functional domain protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 non-specific serine/threonine protein kinase	A0A0G2JTR4 A0A0G2JTU0 A0A0G2JUP3 A0A0G2JXT9 A0A0G2K860 A0A8I5ZMG2 A0A8I5ZPB5 A0A8I5ZZX2 A0A8I6A9Q4 A0A8I6AC12 A0A8I6AL39 A0A8I6AVA8 A0A8I6G7U0 A0A8I6GLR6 A1IGU3 B0BN40 B2GUW2 D3Z9I3 D3ZMS5 D3ZUD0 D3ZYG0 D4A1D2 D4A3T0 D4A646 D4AD85 E9PT59 F1M0Z1 F1M3G7 F1MAI3 G3V9A0 M0R3X3 M0RBM9 O35147 O55043 O88387 O88498 P49185 P54100 P97924 Q5BKC9 Q5FVC2 Q5XXR3 Q63406 Q6P720 Q6Q7Y5 Q6RFZ7 Q6RUV5 Q99JE4 Q9ES67 Q9QX73 Q9WVE9 Q9Z1I6	Abr Akap13 Arhgef1 Arhgef10 Arhgef10l Arhgef11 Arhgef12 Arhgef15 Arhgef16 Arhgef17 Arhgef19 Arhgef2 Arhgef25 Arhgef26 Arhgef3 Arhgef33 Arhgef37 Arhgef38 Arhgef39 Arhgef5 Arhgef6 Arhgef7 Arhgef9 Bad Bcl2l11 Bim Bod Duo Ect2 Ehsh1 Fgd1 Fgd2 Fgd3 Fgd4 Geft Gna13 Grf2 Hapip Itsn Itsn1 Jnk1 Kalrn LOC687105 Lsc Mapk8 Mcf2 Mcf2l Net1 Ngef Obscn Ost Pak3bp Pixb Plekhg2 Plekhg5 Prex1 Prkm8 RGD1565043 Rac Rac1 Rasgrf2 Rt13 Sos1 Sos2 Tech Tiam1 Tiam2 Trio Vav Vav1 Vav2 Vav3	Rattus norvegicus (Norway rat)
Biotin transport and metabolism	Acetyl-CoA carboxylase 1 Biotinidase Holocarboxylase synthetase Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial PDZ domain-containing protein 11 Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial Pyruvate carboxylase, mitochondrial Sodium-dependent multivitamin transporter acetyl-CoA carboxylase	A0A0G2K1F2 A0A8I6A968 A0A8I6A9Z8 O70247 P07633 P11497 P14882 P52873 Q5FVF9 Q5I0C3 Q5XIT9	Acac Acaca Acacb Btd Hlcs Mcca Mccc1 Mccc2 Pc Pcca Pccb Pdzd11 Slc5a6 Smvt	Rattus norvegicus (Norway rat)
Fatty acyl-CoA biosynthesis	(3R)-3-hydroxyacyl-CoA dehydrogenase 3-oxoacyl-[acyl-carrier-protein] reductase ATP-citrate synthase Acetyl-CoA carboxylase 1 Fatty acid synthase Long-chain fatty acid transport protein 2 Lysosomal thioesterase PPT2 MORC family CW-type zinc finger 2 Palmitoyl-protein thioesterase 1 Ribonuclease P/MRP subunit p14 Stearoyl-CoA desaturase 2	A0A8I6A0M8 D4A2C4 O70489 P11497 P12785 P16638 P45479 P97524 Q6MGB5 Q6P7B9 Q7TS56	Acac Acaca Acly Acsvl1 Cbr4 Cln1 Facvl1 Fasn Fatp2 Hsd17b8 Morc2 Ppt Ppt1 Ppt2 Rpp14 Scd2 Slc27a2 Vlacs Vlcs	Rattus norvegicus (Norway rat)
Branched-chain amino acid catabolism	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (Fragment) 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 3-hydroxyacyl-CoA dehydrogenase type-2 3-hydroxyisobutyrate dehydrogenase, mitochondrial 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Acetyl-CoA acetyltransferase, mitochondrial Acyl-CoA dehydrogenase family, member 8 Branched-chain alpha-ketoacid dehydrogenase kinase Branched-chain-amino-acid aminotransferase, cytosolic Branched-chain-amino-acid aminotransferase, mitochondrial Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Dihydrolipoyl dehydrogenase, mitochondrial Enoyl-CoA hydratase, mitochondrial Isovaleryl-CoA dehydrogenase, mitochondrial Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial Methylglutaconyl-CoA hydratase, mitochondrial Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	A0A8I5ZQL5 B2GV15 F1LU71 O35854 O70351 P11960 P12007 P14604 P17764 P29266 P35738 P54690 P70584 Q00972 Q02253 Q5I0C3 Q5XIE6 Q5XIT9 Q6P6R2	Acad8 Acadsb Acat1 Aldh6a1 Auh Bcat1 Bcat2 Bcatm Bckdha Bckdhb Bckdk Dbt Dld Eca40 Echs1 Erab Hadh2 Hibadh Hibch Hsd17b10 Ivd Mcca Mccc1 Mccc2 Mmsdh	Rattus norvegicus (Norway rat)
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P14604 P15650 Q60587 Q64428 Q9WVK7	Acadl Echs1 Had Hadh Hadha Hadhb Hadhsc Schad	Rattus norvegicus (Norway rat)
Beta oxidation of myristoyl-CoA to lauroyl-CoA	Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P15650 Q60587 Q64428	Acadl Hadha Hadhb	Rattus norvegicus (Norway rat)
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial Enoyl-CoA delta isomerase 1, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	P08503 P23965 Q64591	Acadm Dci Decr Decr1 Eci1	Rattus norvegicus (Norway rat)
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Enoyl-[acyl-carrier-protein] reductase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P08503 P14604 Q60587 Q64428 Q9WVK7 Q9Z311	Acadm Echs1 Had Hadh Hadha Hadhb Hadhsc Mecr Nrbf1 Schad	Rattus norvegicus (Norway rat)
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P08503 P14604 Q60587 Q64428 Q9WVK7	Acadm Echs1 Had Hadh Hadha Hadhb Hadhsc Schad	Rattus norvegicus (Norway rat)
Beta oxidation of hexanoyl-CoA to butanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P14604 P15651 Q60587 Q64428 Q9WVK7	Acads Echs1 Had Hadh Hadha Hadhb Hadhsc Schad	Rattus norvegicus (Norway rat)
Beta oxidation of butanoyl-CoA to acetyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial	P14604 P15651 Q9WVK7	Acads Echs1 Had Hadh Hadhsc Schad	Rattus norvegicus (Norway rat)
Beta oxidation of palmitoyl-CoA to myristoyl-CoA	Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	P45953 Q60587 Q64428	Acadvl Hadha Hadhb	Rattus norvegicus (Norway rat)
Keratan sulfate biosynthesis	Aggrecan core protein Beta-1,4-galactosyltransferase 3 Beta-1,4-galactosyltransferase 4 Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Carbohydrate sulfotransferase 1 Carbohydrate sulfotransferase 5 Fibromodulin Hexosyltransferase Hexosyltransferase Hexosyltransferase Keratocan Lumican Osteomodulin Prolargin Solute carrier family 35 member D2 Sulfotransferase Type 2 lactosamine alpha-2,3-sialyltransferase UDP-GlcNAc	A0A0G2K3K5 A0A1W2Q5Z7 D3ZEF9 D3ZVD7 D3ZX31 D4A1T9 D4A2A5 D4A3H6 D4A9P8 M0R868 O88419 P07897 P50609 P51886 P61131 P61943 Q02734 Q11205 Q5RJQ0 Q66H69 Q66HH1 Q6P768 Q9EQP5 Q9Z1S7	Acan Agc Agc1 B3gnt2 B3gnt3 B3gnt4 B3gnt7 B4galt2 B4galt3 B4galt4 B4galt5 B4galt6 Chst1 Chst2 Chst5 Fmod Kera Lcn Ldc Lum Omd Prelp Siat10 Siat4b Siat4c Siat5 Siat6 Slc35d2 St3gal1 St3gal2 St3gal3 St3gal4 St3gal6	Rattus norvegicus (Norway rat)

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