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Standards Ontologies Notations
alcohol dependence

Summary
Synonym
  • alcoholism
Definition
A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.
Super Class
substance dependence
Disease Ontology
DOID:0050741
Mondo Disease Ontology
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 72 in total
Gene ID Gene Symbol Description Source
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
127 ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
150 ADRA2A adrenoceptor alpha 2A
196 AHR aryl hydrocarbon receptor
217 ALDH2 aldehyde dehydrogenase 2 family member
284 ANGPT1 angiopoietin 1
367 AR androgen receptor
406 BMAL1 basic helix-loop-helix ARNT like 1
627 BDNF brain derived neurotrophic factor
Displaying entries 21 - 30 of 52 in total
Gene ID Gene Symbol Description Source
15550 Htr1a 5-hydroxytryptamine (serotonin) receptor 1A
15551 Htr1b 5-hydroxytryptamine (serotonin) receptor 1B
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
15561 Htr3a 5-hydroxytryptamine (serotonin) receptor 3A
15567 Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
16001 Igf1r insulin-like growth factor I receptor
16181 Il1rn interleukin 1 receptor antagonist
16337 Insr insulin receptor
16846 Lep leptin
17967 Ncam1 neural cell adhesion molecule 1
Displaying entries 11 - 20 of 39 in total
Gene ID Gene Symbol Description Source
25075 Htr1b 5-hydroxytryptamine receptor 1B
25083 Adra2a adrenoceptor alpha 2A
25453 Gdnf glial cell derived neurotrophic factor
25553 Slc6a4 solute carrier family 6 member 4
25601 Oprm1 opioid receptor, mu 1
25608 Lep leptin
25669 Cpe carboxypeptidase E
25718 Igf1r insulin-like growth factor 1 receptor
29335 Oprk1 opioid receptor, kappa 1
29539 Aldh2 aldehyde dehydrogenase 2 family member
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
31251 per period
31309 dnc dunce
31364 Fas2 Fasciclin 2
32554 Lcch3 Ligand-gated chloride channel homolog 3
32674 RSG7 Regulator of G-protein signaling 7
33007 Dop2R Dopamine 2-like receptor
34950 Ca-alpha1D Ca[2+]-channel protein alpha[[1]] subunit D
36411 sca scabrous
36849 DAT Dopamine transporter
37191 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B
Displaying all 4 entries
Gene ID Gene Symbol Description Source
58133 ngfb nerve growth factor b (beta polypeptide)
170581 cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit
561372 comta catechol-O-methyltransferase a
565370 comtb catechol-O-methyltransferase b
Displaying all 10 entries
Gene ID Gene Symbol Description Source Organism
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378605 htr1a.L 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
100127346 grin2a.L glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog Xenopus laevis (African clawed frog)
100488055 cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit Xenopus tropicalis (tropical clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 21 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
176304 dat-1 Sodium-dependent dopamine transporter
176691 gab-1 Gamma-aminobutyric acid receptor subunit beta
177911 Y43C5A.2 Fibrinogen C-terminal domain-containing protein
177940 egl-21 Carboxypeptidase E
178269 lev-1 Acetylcholine receptor subunit beta-type lev-1
179347 dop-2 Dopamine receptor 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
851006 ECM38 gamma-glutamyltransferase
The Human Phenotype Ontology
Displaying 1 entry
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
Displaying all 2 entries
Gene ID Gene Symbol Description
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024