renal fibrosis

Summary
Definition
A kidney disease that is characterized by progressive detrimental connective tissue deposition of the kidney parenchyma leading to deterioration of renal function.
Super Class
kidney disease
Disease Ontology
DOID:0050855
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 23 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
1191 CLU clusterin
1536 CYBB cytochrome b-245 beta chain
1573 CYP2J2 cytochrome P450 family 2 subfamily J member 2
1636 ACE angiotensin I converting enzyme
1889 ECE1 endothelin converting enzyme 1
1909 EDNRA endothelin receptor type A
2022 ENG endoglin
2204 FCAR Fc alpha receptor
2671 GFER growth factor, augmenter of liver regeneration
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
17395 Mmp9 matrix metallopeptidase 9
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
20852 Stat6 signal transducer and activator of transcription 6
21898 Tlr4 toll-like receptor 4
24088 Tlr2 toll-like receptor 2
83995 Mmp1a matrix metallopeptidase 1a (interstitial collagenase)
114886 Cygb cytoglobin
230857 Ece1 endothelin converting enzyme 1
338346 Gpr21 G protein-coupled receptor 21
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
83516 Ppargc1a PPARG coactivator 1 alpha
Displaying all 5 entries
Gene ID Gene Symbol Description Source
33005 Nep3 Neprilysin 3
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
43222 Tl Toll
43558 Tace tace
Displaying 1 entry
Gene ID Gene Symbol Description Source
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying all 8 entries
Gene ID Gene Symbol Description Source
173685 nep-11 Neprilysin-11
174787 nep-1 Neprilysin-1
175383 zmp-2 Matrix metalloproteinase-B
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
181041 adm-4 Disintegrin and metalloproteinase domain-containing protein 17 homolog

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024