neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 106 in total
Gene ID Gene Symbol Description Source
50 ACO2 aconitase 2
334 APLP2 amyloid beta precursor like protein 2
387 RHOA ras homolog family member A
388 RHOB ras homolog family member B
389 RHOC ras homolog family member C
847 CAT catalase
1778 DYNC1H1 dynein cytoplasmic 1 heavy chain 1
1855 DVL1 dishevelled segment polarity protein 1
1857 DVL3 dishevelled segment polarity protein 3
2011 MARK2 microtubule affinity regulating kinase 2
Displaying entries 1 - 10 of 73 in total
Gene ID Gene Symbol Description Source
11804 Aplp2 amyloid beta precursor-like protein 2
13424 Dync1h1 dynein cytoplasmic 1 heavy chain 1
13542 Dvl1 dishevelled segment polarity protein 1
13728 Mark2 MAP/microtubule affinity regulating kinase 2
13856 Epo erythropoietin
14473 Gc vitamin D binding protein
14799 Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1)
14800 Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2)
14802 Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4)
14807 Grik3 glutamate receptor, ionotropic, kainate 3
Displaying entries 21 - 30 of 33 in total
Gene ID Gene Symbol Description Source
84487 Slc17a6 solute carrier family 17 member 6
94198 Psmb1 proteasome 20S subunit beta 1
157074 Sdha succinate dehydrogenase complex flavoprotein subunit A
171086 Trak2 trafficking kinesin protein 2
266767 Slc17a8 solute carrier family 17 member 8
287545 Sarm1 sterile alpha and TIR motif containing 1
296851 Pon2 paraoxonase 2
298521 Grik3 glutamate ionotropic receptor kainate type subunit 3
300733 Tspan3 tetraspanin 3
312086 Pon3 paraoxonase 3
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
38742 GluRIA Glutamate receptor IA
38895 Sarm Sterile alpha and Armadillo motif
39836 st scarlet
40665 Nmdar1 NMDA receptor 1
43582 Tpi Triose phosphate isomerase
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
181035 deg-1 Degenerin deg-1
181166 pkc-2 Protein kinase C;Protein kinase C-like 2
181728 mec-4 Degenerin mec-4
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188744 glt-4 Amino acid transporter;Putative sodium-dependent excitatory amino acid transporter glt-4
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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