dementia

Summary
Definition
A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior.
Super Class
cognitive disorder
Disease Ontology
DOID:1307
UMLS
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 23 in total
Gene ID Gene Symbol Description Source
581 BAX BCL2 associated X, apoptosis regulator
590 BCHE butyrylcholinesterase
832 CAPZB capping actin protein of muscle Z-line subunit beta
1813 DRD2 dopamine receptor D2
1869 E2F1 E2F transcription factor 1
1956 EGFR epidermal growth factor receptor
2896 GRN granulin precursor
3084 NRG1 neuregulin 1
3156 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
3480 IGF1R insulin like growth factor 1 receptor
Displaying entries 11 - 18 of 18 in total
Gene ID Gene Symbol Description Source
17762 Mapt microtubule-associated protein tau
18053 Ngfr nerve growth factor receptor (TNFR superfamily, member 16)
18132 Notch4 notch 4
18979 Pon1 paraoxonase 1
22359 Vldlr very low density lipoprotein receptor
23821 Bace1 beta-site APP cleaving enzyme 1
27226 Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
30052 Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor
Displaying all 8 entries
Gene ID Gene Symbol Description Source
24318 Drd2 dopamine receptor D2
24596 Ngfr nerve growth factor receptor
25675 Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase
25718 Igf1r insulin-like growth factor 1 receptor
29143 Grn granulin precursor
29392 Bace1 beta-secretase 1
84024 Pon1 paraoxonase 1
116565 Lrpap1 LDL receptor related protein associated protein 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source
33007 Dop2R Dopamine 2-like receptor
37455 Egfr Epidermal growth factor receptor
38657 vn vein
41625 Ace Acetylcholine esterase
42549 InR Insulin-like receptor
42803 Hmgcr HMG Coenzyme A reductase
Displaying 1 entry
Gene ID Gene Symbol Description Source
447803 pon1 paraoxonase 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
174116 gldi-2 EGF-like domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
179347 dop-2 Dopamine receptor 2
181706 ace-1 Acetylcholinesterase 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
856014 GLR1 glutathione-disulfide reductase GLR1

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