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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
toxic shock syndrome
Summary
- Synonym
-
- TSS
- toxic shock
- Definition
- A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.
- Super Class
- commensal bacterial infectious disease
External Links
- Disease Ontology
- DOID:14115
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3122 | HLA-DRA | major histocompatibility complex, class II, DR alpha | |
| 3123 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | |
| 3304 | HSPA1B | heat shock protein family A (Hsp70) member 1B | |
| 3458 | IFNG | interferon gamma | |
| 3557 | IL1RN | interleukin 1 receptor antagonist | |
| 3586 | IL10 | interleukin 10 | |
| 4153 | MBL2 | mannose binding lectin 2 | |
| 4158 | MC2R | melanocortin 2 receptor | |
| 4282 | MIF | macrophage migration inhibitory factor | |
| 4843 | NOS2 | nitric oxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16181 | Il1rn | interleukin 1 receptor antagonist | |
| 17195 | Mbl2 | mannose-binding lectin (protein C) 2 | |
| 17200 | Mc2r | melanocortin 2 receptor | |
| 18566 | Pdcd1 | programmed cell death 1 | |
| 19123 | Proc | protein C | |
| 19288 | Ptx3 | pentraxin related gene | |
| 19701 | Ren1 | renin 1 structural | |
| 20296 | Ccl2 | C-C motif chemokine ligand 2 | |
| 20317 | Serpinf1 | serine (or cysteine) peptidase inhibitor, clade F, member 1 | |
| 20343 | Sell | selectin, lymphocyte |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24153 | A2m | alpha-2-macroglobulin | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24334 | Eno2 | enolase 2 | |
| 24472 | Hspa1a | heat shock protein family A (Hsp70) member 1A | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24715 | Ren | renin | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24816 | Tbxa2r | thromboxane A2 receptor | |
| 24835 | Tnf | tumor necrosis factor | |
| 25268 | Proc | protein C, inactivator of coagulation factors Va and VIIIa |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 33351 | Eno | Enolase | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 41549 | Octbeta2R | Octopamine beta2 receptor | |
| 45815 | Spn27A | Serpin 27A | |
| 49804 | Spn88Ea | Serpin 88Ea | |
| 49808 | Spn42Dd | Serpin 42Dd |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174423 | enol-1 | Enolase | |
| 178585 | srp-1 | Serpin domain-containing protein | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179195 | srp-7 | Serpin domain-containing protein | |
| 180251 | asp-1 | Aspartic protease 1 | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 853169 | ENO1 | phosphopyruvate hydratase ENO1 | |
| 854575 | ERR1 | phosphopyruvate hydratase ERR1 | |
| 855373 | ERR3 | phosphopyruvate hydratase ERR3 | |
| 855848 | ERR2 | phosphopyruvate hydratase ERR2 | |
| 855949 | PEP4 | proteinase A | |
| 856579 | ENO2 | phosphopyruvate hydratase ENO2 |
