toxic shock syndrome

Summary
Synonym
  • TSS
  • toxic shock
Definition
A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.
Super Class
commensal bacterial infectious disease
Disease Ontology
DOID:14115
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 37 in total
Gene ID Gene Symbol Description Source
3122 HLA-DRA major histocompatibility complex, class II, DR alpha
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3304 HSPA1B heat shock protein family A (Hsp70) member 1B
3458 IFNG interferon gamma
3557 IL1RN interleukin 1 receptor antagonist
3586 IL10 interleukin 10
4153 MBL2 mannose binding lectin 2
4158 MC2R melanocortin 2 receptor
4282 MIF macrophage migration inhibitory factor
4843 NOS2 nitric oxide synthase 2
Displaying entries 11 - 20 of 32 in total
Gene ID Gene Symbol Description Source
16181 Il1rn interleukin 1 receptor antagonist
17195 Mbl2 mannose-binding lectin (protein C) 2
17200 Mc2r melanocortin 2 receptor
18566 Pdcd1 programmed cell death 1
19123 Proc protein C
19288 Ptx3 pentraxin related gene
19701 Ren1 renin 1 structural
20296 Ccl2 C-C motif chemokine ligand 2
20317 Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1
20343 Sell selectin, lymphocyte
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
25325 Il10 interleukin 10
25706 Cckbr cholecystokinin B receptor
25712 Ifng interferon gamma
29259 Sell selectin L
29436 Tfpi tissue factor pathway inhibitor
60582 Il1rn interleukin 1 receptor antagonist
81811 Thpol1 thrombopoietin like 1
192155 Sftpb surfactant protein B
295703 Serping1 serpin family G member 1
Displaying all 8 entries
Gene ID Gene Symbol Description Source
33351 Eno Enolase
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
41549 Octbeta2R Octopamine beta2 receptor
45815 Spn27A Serpin 27A
49804 Spn88Ea Serpin 88Ea
49808 Spn42Dd Serpin 42Dd
Displaying 1 entry
Gene ID Gene Symbol Description Source
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
174423 enol-1 Enolase
178585 srp-1 Serpin domain-containing protein
178672 srp-3 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
180251 asp-1 Aspartic protease 1
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
Displaying all 6 entries
Gene ID Gene Symbol Description Source
853169 ENO1 phosphopyruvate hydratase ENO1
854575 ERR1 phosphopyruvate hydratase ERR1
855373 ERR3 phosphopyruvate hydratase ERR3
855848 ERR2 phosphopyruvate hydratase ERR2
855949 PEP4 proteinase A
856579 ENO2 phosphopyruvate hydratase ENO2

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