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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 28 | ABO | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | |
| 101 | ADAM8 | ADAM metallopeptidase domain 8 | |
| 128 | ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | |
| 134 | ADORA1 | adenosine A1 receptor | |
| 135 | ADORA2A | adenosine A2a receptor | |
| 142 | PARP1 | poly(ADP-ribose) polymerase 1 | |
| 154 | ADRB2 | adrenoceptor beta 2 | |
| 177 | AGER | advanced glycosylation end-product specific receptor | |
| 185 | AGTR1 | angiotensin II receptor type 1 | |
| 186 | AGTR2 | angiotensin II receptor type 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 22353 | Vip | vasoactive intestinal polypeptide | |
| 23844 | Clca1 | chloride channel accessory 1 | |
| 24047 | Ccl19 | C-C motif chemokine ligand 19 | |
| 24088 | Tlr2 | toll-like receptor 2 | |
| 27226 | Pla2g7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | |
| 50929 | Il22 | interleukin 22 | |
| 56221 | Ccl24 | C-C motif chemokine ligand 24 | |
| 58861 | Cysltr1 | cysteinyl leukotriene receptor 1 | |
| 59035 | Carm1 | coactivator-associated arginine methyltransferase 1 | |
| 60505 | Il21 | interleukin 21 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24180 | Agtr1a | angiotensin II receptor, type 1a | |
| 24182 | Agtr2 | angiotensin II receptor, type 2 | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24232 | C3 | complement C3 | |
| 24255 | Cftr | CF transmembrane conductance regulator | |
| 24260 | Chrm3 | cholinergic receptor, muscarinic 3 | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24464 | Hp | haptoglobin | |
| 24493 | Il1a | interleukin 1 alpha | |
| 24598 | Nos1 | nitric oxide synthase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 387303 | gbgt1l4 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 | |
| 394082 | slc18a3b | solute carrier family 18 member 3b | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 436718 | rhocb | ras homolog family member Cb | |
| 447881 | gbgt1l3 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373580 | crhr1.2.S | corticotropin releasing hormone receptor 1, gene 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 397750 | hmgcr.L | 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 399298 | ntf3.L | neurotrophin 3 L homeolog | Xenopus laevis (African clawed frog) | |
| 495825 | abo.3.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog | Xenopus laevis (African clawed frog) | |
| 549437 | abo.3 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 | Xenopus tropicalis (tropical clawed frog) | |
| 549858 | abo.2 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 | Xenopus tropicalis (tropical clawed frog) | |
| 550054 | abo | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179125 | srp-6 | Serpin domain-containing protein | |
| 179195 | srp-7 | Serpin domain-containing protein | |
| 179962 | gar-3 | Muscarinic acetylcholine receptor gar-3 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180042 | dpf-1 | Dipeptidyl peptidase family member 1 | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180628 | cht-1 | putative endochitinase | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180836 | W01C8.5 | DM13 domain-containing protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850462 | GIT1 | Git1p | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 851977 | CTS2 | putative chitinase | |
| 853671 | STE6 | ATP-binding cassette a-factor transporter STE6 | |
| 853978 | NFT1 | putative multidrug transporter NFT1 | |
| 854394 | STE13 | Ste13p | |
| 854900 | HMG1 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 | |
| 856294 | RHO1 | Rho family GTPase RHO1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
