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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 28 | ABO | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | |
| 101 | ADAM8 | ADAM metallopeptidase domain 8 | |
| 128 | ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | |
| 134 | ADORA1 | adenosine A1 receptor | |
| 135 | ADORA2A | adenosine A2a receptor | |
| 142 | PARP1 | poly(ADP-ribose) polymerase 1 | |
| 154 | ADRB2 | adrenoceptor beta 2 | |
| 177 | AGER | advanced glycosylation end-product specific receptor | |
| 185 | AGTR1 | angiotensin II receptor type 1 | |
| 186 | AGTR2 | angiotensin II receptor type 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11421 | Ace | angiotensin I converting enzyme | |
| 11501 | Adam8 | a disintegrin and metallopeptidase domain 8 | |
| 11539 | Adora1 | adenosine A1 receptor | |
| 11540 | Adora2a | adenosine A2a receptor | |
| 11555 | Adrb2 | adrenergic receptor, beta 2 | |
| 11596 | Ager | advanced glycosylation end product-specific receptor | |
| 11607 | Agtr1a | angiotensin II receptor, type 1a | |
| 11609 | Agtr2 | angiotensin II receptor, type 2 | |
| 11699 | Ambp | alpha 1 microglobulin/bikunin precursor | |
| 12062 | Bdkrb2 | bradykinin receptor, beta 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 170926 | Cysltr2 | cysteinyl leukotriene receptor 2 | |
| 192155 | Sftpb | surfactant protein B | |
| 246097 | Fas | Fas cell surface death receptor | |
| 260320 | F7 | coagulation factor VII | |
| 286934 | Havcr1 | hepatitis A virus cellular receptor 1 | |
| 286963 | Cyp2d5 | cytochrome P450, family 2, subfamily d, polypeptide 5 | |
| 287222 | Timd2 | T-cell immunoglobulin and mucin domain containing 2 | |
| 287287 | Il4 | interleukin 4 | |
| 287561 | Ccl7 | C-C motif chemokine ligand 7 | |
| 289211 | Fcgr2b | Fc gamma receptor 2B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 35334 | CarT | Carcinine transporter | |
| 36417 | Balat | Beta-alanine transporter | |
| 36428 | Mdr49 | Multi drug resistance 49 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 387303 | gbgt1l4 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 | |
| 394082 | slc18a3b | solute carrier family 18 member 3b | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 436718 | rhocb | ras homolog family member Cb | |
| 447881 | gbgt1l3 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 100497509 | abo.4 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 | Xenopus tropicalis (tropical clawed frog) | |
| 108698211 | abo.2.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 108698863 | abo.4.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog | Xenopus laevis (African clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179125 | srp-6 | Serpin domain-containing protein | |
| 179195 | srp-7 | Serpin domain-containing protein | |
| 179962 | gar-3 | Muscarinic acetylcholine receptor gar-3 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180042 | dpf-1 | Dipeptidyl peptidase family member 1 | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180628 | cht-1 | putative endochitinase | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180836 | W01C8.5 | DM13 domain-containing protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850462 | GIT1 | Git1p | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 851977 | CTS2 | putative chitinase | |
| 853671 | STE6 | ATP-binding cassette a-factor transporter STE6 | |
| 853978 | NFT1 | putative multidrug transporter NFT1 | |
| 854394 | STE13 | Ste13p | |
| 854900 | HMG1 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 | |
| 856294 | RHO1 | Rho family GTPase RHO1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
