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Standards Ontologies Notations
asthma

Summary
Synonym
  • bronchial hyperreactivity
  • chronic obstructive asthma
  • chronic obstructive asthma with acute exacerbation
  • chronic obstructive asthma with status asthmaticus
Definition
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Super Class
bronchial disease
Disease Ontology
DOID:2841
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 206 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
101 ADAM8 ADAM metallopeptidase domain 8
128 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
134 ADORA1 adenosine A1 receptor
135 ADORA2A adenosine A2a receptor
142 PARP1 poly(ADP-ribose) polymerase 1
154 ADRB2 adrenoceptor beta 2
177 AGER advanced glycosylation end-product specific receptor
185 AGTR1 angiotensin II receptor type 1
186 AGTR2 angiotensin II receptor type 2
Displaying entries 51 - 60 of 191 in total
Gene ID Gene Symbol Description Source
14161 Fga fibrinogen alpha chain
14473 Gc vitamin D binding protein
14764 Ptgdr2 prostaglandin D2 receptor 2
14815 Nr3c1 nuclear receptor subfamily 3, group C, member 1
14960 H2-Aa histocompatibility 2, class II antigen A, alpha
14961 H2-Ab1 histocompatibility 2, class II antigen A, beta 1
14964 H2-D1 histocompatibility 2, D region locus 1
14969 H2-Eb1 histocompatibility 2, class II antigen E beta
14972 H2-K1 histocompatibility 2, K1, K region
14990 H2-M2 histocompatibility 2, M region locus 2
Displaying entries 41 - 50 of 112 in total
Gene ID Gene Symbol Description Source
25591 Parp1 poly (ADP-ribose) polymerase 1
25608 Lep leptin
25627 Cma1 chymase 1
25660 Cd28 Cd28 molecule
25670 Il15 interleukin 15
25675 Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase
25704 Il2ra interleukin 2 receptor subunit alpha
25712 Ifng interferon gamma
25746 Il2rb interleukin 2 receptor subunit beta
29139 Dcn decorin
Displaying entries 11 - 20 of 33 in total
Gene ID Gene Symbol Description Source
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
37455 Egfr Epidermal growth factor receptor
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
37895 SerT Serotonin transporter
38223 Cht2 Chitinase 2
38326 Pxn Peroxidasin
38726 Mdr65 Multi drug resistance 65
39015 TrpA1 Transient receptor potential cation channel A1
40404 ORMDL Orosomucoid 1-like
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
394082 slc18a3b solute carrier family 18 member 3b
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
436718 rhocb ras homolog family member Cb
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source Organism
373580 crhr1.2.S corticotropin releasing hormone receptor 1, gene 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
399298 ntf3.L neurotrophin 3 L homeolog Xenopus laevis (African clawed frog)
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172841 45566 Organic cation transporter 1
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175504 pat-3 Integrin beta pat-3
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178118 trpa-1 Ion transport domain-containing protein;Transient receptor potential cation channel subfamily A member 1 homolog
178215 pgp-1 Multidrug resistance protein pgp-1
178274 cho-1 High-affinity choline transporter 1
Displaying all 8 entries
Gene ID Gene Symbol Description Source
850462 GIT1 Git1p
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
851977 CTS2 putative chitinase
853671 STE6 ATP-binding cassette a-factor transporter STE6
853978 NFT1 putative multidrug transporter NFT1
854394 STE13 Ste13p
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
856294 RHO1 Rho family GTPase RHO1
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
HP:0000006 Autosomal dominant inheritance
HP:0002099 Asthma
Displaying 1 entry
Gene ID Gene Symbol Description
240 ALOX5 arachidonate 5-lipoxygenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024