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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
pulmonary fibrosis
Summary
- Synonym
-
- Fibrosis of lung
- Definition
- An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
- Super Class
- interstitial lung disease
External Links
- Disease Ontology
- DOID:3770
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 177 | AGER | advanced glycosylation end-product specific receptor | |
| 182 | JAG1 | jagged canonical Notch ligand 1 | |
| 183 | AGT | angiotensinogen | |
| 240 | ALOX5 | arachidonate 5-lipoxygenase | |
| 301 | ANXA1 | annexin A1 | |
| 572 | BAD | BCL2 associated agonist of cell death | |
| 623 | BDKRB1 | bradykinin receptor B1 | |
| 627 | BDNF | brain derived neurotrophic factor | |
| 847 | CAT | catalase | |
| 948 | CD36 | CD36 molecule (CD36 blood group) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12773 | Ccr4 | C-C motif chemokine receptor 4 | |
| 12774 | Ccr5 | C-C motif chemokine receptor 5 | |
| 12776 | Ccr8 | C-C motif chemokine receptor 8 | |
| 12842 | Col1a1 | collagen, type I, alpha 1 | |
| 12843 | Col1a2 | collagen, type I, alpha 2 | |
| 12981 | Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | |
| 13649 | Egfr | epidermal growth factor receptor | |
| 13653 | Egr1 | early growth response 1 | |
| 15234 | Hgf | hepatocyte growth factor | |
| 15510 | Hspd1 | heat shock protein 1 (chaperonin) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24179 | Agt | angiotensinogen | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24260 | Chrm3 | cholinergic receptor, muscarinic 3 | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24446 | Hgf | hepatocyte growth factor | |
| 24484 | Igfbp3 | insulin-like growth factor binding protein 3 | |
| 24493 | Il1a | interleukin 1 alpha | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24773 | Sftpa1 | surfactant protein A1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 37455 | Egfr | Epidermal growth factor receptor | |
| 37892 | mAChR-A | muscarinic Acetylcholine Receptor, A-type | |
| 38868 | Snmp2 | Sensory neuron membrane protein 2 | |
| 42514 | Snmp1 | Sensory neuron membrane protein 1 | |
| 43275 | Ser | Serrate | |
| 251900 | GlcAT-I | Glucuronyltransferase I |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30718 | notch1a | notch receptor 1a | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 386856 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | |
| 548607 | b3gat1a | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 100332644 | b3gat1b | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) | |
| 100037907 | b3gat1 | beta-1,3-glucuronyltransferase 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180628 | cht-1 | putative endochitinase | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180812 | scav-1 | SCAVenger receptor (CD36 family) related |
