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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
systemic scleroderma
Summary
- Synonym
-
- Scleroderma
- Scleroderma syndrome
- progressive systemic sclerosis
- systemic sclerosis
- Definition
- A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
- Super Class
- scleroderma
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1277 | COL1A1 | collagen type I alpha 1 chain | |
| 1281 | COL3A1 | collagen type III alpha 1 chain | |
| 1356 | CP | ceruloplasmin | |
| 1435 | CSF1 | colony stimulating factor 1 | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 1906 | EDN1 | endothelin 1 | |
| 2006 | ELN | elastin | |
| 2099 | ESR1 | estrogen receptor 1 | |
| 2147 | F2 | coagulation factor II, thrombin | |
| 2200 | FBN1 | fibrillin 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 56744 | Pf4 | platelet factor 4 | |
| 80901 | Cxcr6 | C-X-C motif chemokine receptor 6 | |
| 83964 | Jam3 | junction adhesion molecule 3 | |
| 83995 | Mmp1a | matrix metallopeptidase 1a (interstitial collagenase) | |
| 209590 | Il23r | interleukin 23 receptor | |
| 246779 | Il27 | interleukin 27 | |
| 279028 | Adamts13 | ADAM metallopeptidase with thrombospondin type 1 motif 13 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24179 | Agt | angiotensinogen | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24232 | C3 | complement C3 | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24446 | Hgf | hepatocyte growth factor | |
| 24484 | Igfbp3 | insulin-like growth factor binding protein 3 | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24854 | Clu | clusterin | |
| 24890 | Esr1 | estrogen receptor 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 36868 | Idgf6 | Imaginal disc growth factor 6 | |
| 37104 | Idgf5 | Imaginal disc growth factor 5 | |
| 42490 | Mvl | Malvolio |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 791973 | cxcr3.2 | chemokine (C-X-C motif) receptor 3, tandem duplicate 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174044 | sma-6 | Serine/threonine-protein kinase receptor sma-6 | |
| 175182 | ver-1 | Protein ver-1 | |
| 176076 | fbn-1 | EGF-like domain-containing protein | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 176829 | daf-1 | Cell surface receptor daf-1 | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein |
