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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
systemic scleroderma
Summary
- Synonym
-
- Scleroderma
- Scleroderma syndrome
- progressive systemic sclerosis
- systemic sclerosis
- Definition
- A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
- Super Class
- scleroderma
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4312 | MMP1 | matrix metallopeptidase 1 | |
| 4314 | MMP3 | matrix metallopeptidase 3 | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 4582 | MUC1 | mucin 1, cell surface associated | |
| 4803 | NGF | nerve growth factor | |
| 4855 | NOTCH4 | notch receptor 4 | |
| 5054 | SERPINE1 | serpin family E member 1 | |
| 5175 | PECAM1 | platelet and endothelial cell adhesion molecule 1 | |
| 5345 | SERPINF2 | serpin family F member 2 | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 14962 | Cfb | complement factor B | |
| 15234 | Hgf | hepatocyte growth factor | |
| 15289 | Hmgb1 | high mobility group box 1 | |
| 15894 | Icam1 | intercellular adhesion molecule 1 | |
| 15978 | Ifng | interferon gamma | |
| 16009 | Igfbp3 | insulin-like growth factor binding protein 3 | |
| 16163 | Il13 | interleukin 13 | |
| 16171 | Il17a | interleukin 17A | |
| 16177 | Il1r1 | interleukin 1 receptor, type I | |
| 16183 | Il2 | interleukin 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25008 | Lta | lymphotoxin alpha | |
| 25459 | Hmgb1 | high mobility group box 1 | |
| 25464 | Icam1 | intercellular adhesion molecule 1 | |
| 25589 | Kdr | kinase insert domain receptor | |
| 25703 | Rbp4 | retinol binding protein 4 | |
| 25712 | Ifng | interferon gamma | |
| 29360 | Selenop | selenoprotein P | |
| 29393 | Col1a1 | collagen type I alpha 1 chain | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| 29583 | Pecam1 | platelet and endothelial cell adhesion molecule 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 36868 | Idgf6 | Imaginal disc growth factor 6 | |
| 37104 | Idgf5 | Imaginal disc growth factor 5 | |
| 42490 | Mvl | Malvolio |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 791973 | cxcr3.2 | chemokine (C-X-C motif) receptor 3, tandem duplicate 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174044 | sma-6 | Serine/threonine-protein kinase receptor sma-6 | |
| 175182 | ver-1 | Protein ver-1 | |
| 176076 | fbn-1 | EGF-like domain-containing protein | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 176829 | daf-1 | Cell surface receptor daf-1 | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein |
