heroin dependence

Summary
Definition
An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.
Super Class
opiate dependence
Disease Ontology
DOID:9976
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 1 - 10 of 35 in total
Gene ID Gene Symbol Description Source
18 ABAT 4-aminobutyrate aminotransferase
43 ACHE acetylcholinesterase (Yt blood group)
148 ADRA1A adrenoceptor alpha 1A
217 ALDH2 aldehyde dehydrogenase 2 family member
355 FAS Fas cell surface death receptor
590 BCHE butyrylcholinesterase
627 BDNF brain derived neurotrophic factor
1129 CHRM2 cholinergic receptor muscarinic 2
1312 COMT catechol-O-methyltransferase
1385 CREB1 cAMP responsive element binding protein 1
Displaying entries 1 - 10 of 34 in total
Gene ID Gene Symbol Description Source
11423 Ache acetylcholinesterase
11549 Adra1a adrenergic receptor, alpha 1a
11669 Aldh2 aldehyde dehydrogenase 2, mitochondrial
12038 Bche butyrylcholinesterase
12064 Bdnf brain derived neurotrophic factor
12846 Comt catechol-O-methyltransferase
13095 Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29
13162 Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
13488 Drd1 dopamine receptor D1
13489 Drd2 dopamine receptor D2
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
25601 Oprm1 opioid receptor, mu 1
29237 Penk proenkephalin
29238 Drd3 dopamine receptor D3
29335 Oprk1 opioid receptor, kappa 1
29412 Adra1a adrenoceptor alpha 1A
29539 Aldh2 aldehyde dehydrogenase 2 family member
29709 Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2
50592 Gria1 glutamate ionotropic receptor AMPA type subunit 1
79246 Htr3a 5-hydroxytryptamine receptor 3A
81645 Chrm2 cholinergic receptor, muscarinic 2
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
43838 mGluR metabotropic Glutamate Receptor
Displaying all 4 entries
Gene ID Gene Symbol Description Source
58133 ngfb nerve growth factor b (beta polypeptide)
114549 ache acetylcholinesterase (Yt blood group)
561372 comta catechol-O-methyltransferase a
565370 comtb catechol-O-methyltransferase b
Displaying all 4 entries
Gene ID Gene Symbol Description Source Organism
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
100127346 grin2a.L glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
175076 ace-3 Carboxylic ester hydrolase
175999 glr-2 Glutamate receptor 2
176204 glr-1 Glutamate receptor 1
176304 dat-1 Sodium-dependent dopamine transporter
176691 gab-1 Gamma-aminobutyric acid receptor subunit beta
178215 pgp-1 Multidrug resistance protein pgp-1
179347 dop-2 Dopamine receptor 2
179962 gar-3 Muscarinic acetylcholine receptor gar-3
180714 dop-1 Dopamine receptor 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
853671 STE6 ATP-binding cassette a-factor transporter STE6

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