GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1551 - 1575** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Acetylcholine inhibits contraction of outer hair cells	Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Neuronal acetylcholine receptor subunit alpha-10 Neuronal acetylcholine receptor subunit alpha-9 Small conductance calcium-activated potassium channel protein 2	Q12791 Q16558 Q9GZZ6 Q9H2S1 Q9UGM1	CHRNA10 CHRNA9 KCNMA KCNMA1 KCNMB1 KCNN2 NACHRA10 NACHRA9 SLO	Homo sapiens (human)
Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)	High affinity choline transporter 1	Q9GZV3	CHT1 SLC5A7	Homo sapiens (human)
Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)	High affinity choline transporter 1	Q9GZV3	CHT1 SLC5A7	Homo sapiens (human)
IkBA variant leads to EDA-ID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit Transcription factor p65	O14920 O15111 P19838 P25963 Q00653 Q04206 Q9Y6K9	CHUK FIP3 IKBA IKBKB IKBKG IKKA IKKB LYT10 MAD3 NEMO NFKB1 NFKB2 NFKB3 NFKBI NFKBIA RELA TCF16	Homo sapiens (human)
IKBKB deficiency causes SCID	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16	Homo sapiens (human)
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator	O14920 O15111 Q9Y6K9	CHUK FIP3 IKBKB IKBKG IKKA IKKB NEMO TCF16	Homo sapiens (human)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein 1 Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	O75339 P01344 P05019 P08069	CILP IBP1 IGF1 IGF1R IGF2	Homo sapiens (human)
Reelin signalling pathway	Disabled homolog 1 Reelin SH3 domain-containing kinase-binding protein 1 Tyrosine-protein kinase Fyn Very low-density lipoprotein receptor	O75553 P06241 P78509 P98155 Q96B97	CIN85 DAB1 FYN RELN SH3KBP1 VLDLR	Homo sapiens (human)
SARS-CoV-2 targets PDZ proteins in cell-cell junction	Envelope small membrane protein Gap junction alpha-1 protein InaD-like protein Protein PALS1 Protein crumbs homolog 3 Tight junction protein ZO-1	P0DTC4 P17302 Q07157 Q8N3R9 Q8NI35 Q9BUF7	CIPP CRB3 E GJA1 GJAL INADL MPP5 PALS1 PATJ TJP1 ZO1	Homo sapiens (human)
Regulation of IFNG signaling	E3 SUMO-protein ligase PIAS1 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6	O14543 O15524 O60674 O75925 P01579 P15260 P18031 P23458 P29350 P38484 P63165 Q06124	CIS3 DDXBP1 HCP IFNG IFNGR1 IFNGR2 IFNGT1 JAK1 JAK1A JAK1B JAK2 PIAS1 PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SMT3C SMT3H3 SOCS1 SOCS3 SSI1 SSI3 SUMO1 TIP3 UBL1	Homo sapiens (human)
Regulation of IFNA/IFNB signaling	Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha/beta receptor 1 Interferon beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 2 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6 Ubl carboxyl-terminal hydrolase 18	O14543 O15524 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P17181 P18031 P23458 P29350 P29597 P32881 P52630 Q06124 Q9UMW8	CIS3 HCP IFB IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR IFNAR1 IFNB IFNB1 ISG43 JAK1 JAK1A JAK1B PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT2 TIP3 TYK2 USP18	Homo sapiens (human)
WNT mediated activation of DVL	Casein kinase I isoform epsilon Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3	O14640 O14641 O14986 P19784 P49674 P67870 P68400 Q92997	CK2A1 CK2A2 CK2N CSNK1E CSNK2A1 CSNK2A2 CSNK2B DVL1 DVL2 DVL3 G5A KIAA0208 PIP5K1B STM7	Homo sapiens (human)
Entry of Influenza Virion into Host Cell via Endocytosis	Clathrin heavy chain 1 Clathrin light chain A Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821 P09496 Q00610	CLH17 CLTA CLTC CLTCL2 HA KIAA0034 M NA NP NS PA PB1 PB2	Homo sapiens (human)
Signaling by LTK in cancer	CAP-Gly domain-containing linker protein 1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	O00459 P27361 P27986 P28482 P30622 P42336 P42338	CLIP1 CYLN1 ERK1 ERK2 GRB1 MAPK1 MAPK3 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKM1 PRKM2 PRKM3 RSN	Homo sapiens (human)
Lectin pathway of complement activation	Collectin-10 Collectin-11 Ficolin-1 Ficolin-2 Ficolin-3 Mannan-binding lectin serine protease 1 Mannose-binding protein C	O00602 O75636 P11226 P48740 Q15485 Q9BWP8 Q9Y6Z7	CLL1 COLEC1 COLEC10 COLEC11 CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 MASP1 MBL MBL2 PRSS5	Homo sapiens (human)	G49108TO G57321FI
GABA synthesis, release, reuptake and degradation	Complexin-1 DnaJ homolog subfamily C member 5 Glutamate decarboxylase 1 Glutamate decarboxylase 2 Heat shock cognate 71 kDa protein Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2 Vesicular inhibitory amino acid transporter	O14810 P11142 P20336 P21579 P60880 P63027 Q05329 Q16623 Q86UR5 Q99259 Q9H3Z4 Q9H598	CLN4 CPLX1 DNAJC5 GAD GAD1 GAD2 GAD65 GAD67 HSC70 HSP73 HSPA10 HSPA8 KIAA0340 RAB3A RAB3IP2 RIM1 RIMS1 SLC32A1 SNAP SNAP25 STX1 STX1A SVP65 SYB2 SYT SYT1 VAMP2 VGAT VIAAT	Homo sapiens (human)
Insulin processing	Carboxypeptidase E Collectrin ERO1-like protein beta Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 4 Exocyst complex component 5 Exocyst complex component 6 Exocyst complex component 7 Exocyst complex component 8 Insulin Kinesin heavy chain isoform 5A Kinesin heavy chain isoform 5C Kinesin-1 heavy chain Neuroendocrine convertase 1 Neuroendocrine convertase 2 Protein disulfide-isomerase Proton-coupled zinc antiporter SLC30A5 Proton-coupled zinc antiporter SLC30A8 Rab effector MyRIP Ras-related protein Rab-27A Syntaxin-1A Unconventional myosin-Va Vesicle-associated membrane protein 2	O00471 O60282 O60645 P01308 P07237 P16519 P16870 P29120 P33176 P51159 P63027 Q12840 Q16623 Q86YB8 Q8IWU4 Q8IYI6 Q8NFW9 Q8TAD4 Q8TAG9 Q96A65 Q96KP1 Q9HBJ8 Q9NV70 Q9UPT5 Q9Y4I1	CLTRN CPE ERBA2L ERO1B ERO1LB EXO70 EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6 EXOC7 EXOC8 INS KIAA0531 KIAA1067 KIAA1699 KIF5A KIF5B KIF5C KNS KNS1 MYH12 MYO5A MYRIP NEC1 NEC2 NKHC1 NKHC2 P4HB PCSK1 PCSK2 PDI PDIA1 PO4DB RAB27 RAB27A SEC10 SEC10L1 SEC15A SEC15L SEC15L1 SEC3 SEC3L1 SEC5 SEC5L1 SEC6 SEC6L1 SEC8 SEC8L1 SLAC2C SLC30A5 SLC30A8 STX1 STX1A SYB2 TMEM27 VAMP2 ZNT5 ZNT8 ZNTL1 ZTL1	Homo sapiens (human)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-3' exoribonuclease 1 Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 MAP kinase-activated protein kinase 2 Transportin-1 m7GpppN-mRNA hydrolase mRNA decay activator protein ZFP36 mRNA-decapping enzyme 1A	P26651 P31946 P49137 Q06265 Q13868 Q15024 Q5RKV6 Q8IU60 Q8IZH2 Q92973 Q96B26 Q9NPD3 Q9NPI6 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2	CML28 CSL4 DCP1A DCP2 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 G0S24 KIAA0116 KIAA1008 KPNB2 MAPKAPK2 MIP1 MTR3 NUDT20 NUP475 OIP2 PMSCL1 RNF162A RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SEP1 SKI6 SMIF TIS11A TNPO1 TRN TTP XRN1 YWHAB ZFP36	Homo sapiens (human)
mRNA decay by 3' to 5' exoribonuclease	7-methylguanosine phosphate-specific 5'-nucleotidase Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 HBS1-like protein Superkiller complex protein 2 Superkiller complex protein 3 Superkiller complex protein 8 m7GpppX diphosphatase	Q06265 Q13868 Q15024 Q15477 Q5RKV6 Q6PGP7 Q969T7 Q96B26 Q96C86 Q9GZS3 Q9NPD3 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2 Q9Y450	CML28 CSL4 DCPS DCS1 DDX13 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 HBS1 HBS1L HINT5 KIAA0116 KIAA0372 KIAA1008 KIAA1038 MTR3 NT5C3B NT5C3L OIP2 PMSCL1 RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SKI2W SKI6 SKIC2 SKIC3 SKIC8 SKIV2 SKIV2L TTC37 W WDR61	Homo sapiens (human)
Activation of the phototransduction cascade	Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Sodium/potassium/calcium exchanger 1	O60721 P08100 P10523 P11488 P16499 P18545 P29973 P35913 P62873 P63211 Q14028	CNCG CNCG1 CNCG2 CNCG3L CNCG4 CNGA1 CNGB1 GNAT1 GNATR GNB1 GNGT1 KIAA0702 NCKX1 OPN2 PDE6A PDE6B PDE6G PDEA PDEB PDEG RCNC2 RHO SAG SLC24A1	Homo sapiens (human)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	DNA ligase 1 DNA mismatch repair protein Mlh1 DNA mismatch repair protein Msh2 DNA mismatch repair protein Msh3 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Exonuclease 1 Mismatch repair endonuclease PMS2 Proliferating cell nuclear antigen Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P12004 P15927 P18858 P20585 P27694 P28340 P35244 P40692 P43246 P49005 P54278 Q15054 Q9HCU8 Q9UQ84	COCA2 DUC1 DUG EXO1 EXOI HEX1 KIAA0039 LIG1 MLH1 MSH2 MSH3 PCNA PMS2 PMSL2 POLD POLD1 POLD2 POLD3 POLD4 POLDS REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70	Homo sapiens (human)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	DNA ligase 1 DNA mismatch repair protein Mlh1 DNA mismatch repair protein Msh2 DNA mismatch repair protein Msh6 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Exonuclease 1 Mismatch repair endonuclease PMS2 Proliferating cell nuclear antigen Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit	P12004 P15927 P18858 P27694 P28340 P35244 P40692 P43246 P49005 P52701 P54278 Q15054 Q9HCU8 Q9UQ84	COCA2 EXO1 EXOI GTBP HEX1 KIAA0039 LIG1 MLH1 MSH2 MSH6 PCNA PMS2 PMSL2 POLD POLD1 POLD2 POLD3 POLD4 POLDS REPA1 REPA2 REPA3 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70	Homo sapiens (human)
Defective Mismatch Repair Associated With MLH1	DNA mismatch repair protein Mlh1 Mismatch repair endonuclease PMS2	P40692 P54278	COCA2 MLH1 PMS2 PMSL2	Homo sapiens (human)
Defective Mismatch Repair Associated With PMS2	DNA mismatch repair protein Mlh1 Mismatch repair endonuclease PMS2	P40692 P54278	COCA2 MLH1 PMS2 PMSL2	Homo sapiens (human)
Defective CSF2RB causes SMDP5	Cytokine receptor common subunit beta Granulocyte-macrophage colony-stimulating factor receptor subunit alpha Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Surfactant protein C Surfactant-associated protein 3	P07988 P0C7M3 P11686 P15509 P32927 P35247 Q8IWL1 Q8IWL2	COLEC4 COLEC5 COLEC7 CSF2R CSF2RA CSF2RB CSF2RY IL3RB IL5RB PSAP PSPD SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH	Homo sapiens (human)

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