GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **376 - 400** of **1070** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Synthesis of PE	Choline kinase alpha Choline/ethanolamine kinase Choline/ethanolaminephosphotransferase 1 Ethanolamine kinase 2 Ethanolamine-phosphate cytidylyltransferase Ethanolamine-phosphate phospho-lyase Phosphoethanolamine/phosphocholine phosphatase 1 Selenoprotein I ethanolamine kinase phosphatidate phosphatase phosphatidate phosphatase phosphatidate phosphatase	A0A0G2JW03 A0A0G2JY62 A0A8I6AUU1 B4F7D7 D3ZRW8 D3ZXB8 G3V6P4 M0R7F6 O54783 O88637 Q01134 Q6AXM5	Cept1 Chetk Chk Chka Chkb Chkl Ckr Ept1 Etnk1 Etnk2 Etnppl LOC687071 Lpin1 Lpin2 Lpin3 Pcyt2 Phospho1 Selenoi	Rattus norvegicus (Norway rat)
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 High affinity choline transporter 1 Liprin-alpha-3 Liprin-alpha-4 (Fragment) PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular acetylcholine transporter	A0A1B0GWS0 A0A8I6AK94 P21707 P32738 P32851 P60881 P61765 P63012 P63041 P63045 Q62666 Q62769 Q91Z79 Q91Z80 Q9JIR0 Q9JIR4 Q9JMD7	Bzrap1 Chat Cht1 Cplx1 Ppfia1 Ppfia2 Ppfia3 Ppfia4 Rab3a Rbp1 Rim1 Rims1 Sap Slc18a3 Slc5a7 Snap Snap25 Stx1a Stxbp1 Syb2 Syt1 Tspoap1 Unc13b Unc13h2 Unc18a Vacht Vamp2 Vat	Rattus norvegicus (Norway rat)
Sealing of the nuclear envelope (NE) by ESCRT-III	Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4B Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Coiled-coil and C2 domain-containing protein 1B IST1 homolog Spastin Tubulin alpha chain Tubulin alpha-1A chain Tubulin alpha-1B chain Tubulin alpha-1C chain Tubulin alpha-3 chain Tubulin alpha-4A chain Tubulin alpha-8 chain Tubulin beta chain Tubulin beta-2A chain Tubulin beta-2B chain Tubulin beta-3 chain Tubulin beta-4B chain Vacuolar protein sorting-associated protein 4A	A0A8I5ZP83 A0A8I5ZY10 A0A8I6AB52 A0A8I6AQ75 B2RYN7 D4A7H9 F1LUM5 M0R8B6 P68370 P85108 Q3KRE8 Q4QRB4 Q568Z6 Q569C1 Q5FVK6 Q5XIF6 Q68FR8 Q6AY56 Q6AYZ1 Q6P9T8 Q6P9V9 Q793F9 Q8CGS4	Cc2d1b Chmp2a Chmp2b Chmp3 Chmp4b Chmp4c Chmp6 Chmp7 Ist1 LOC679312 Spast Spg4 Tuba1 Tuba1a Tuba1b Tuba1c Tuba2 Tuba3 Tuba3a Tuba3b Tuba4 Tuba4a Tuba6 Tuba8 Tubal3 Tubb1 Tubb2a Tubb2b Tubb2c Tubb3 Tubb4b Vps24 Vps4a vps4-A	Rattus norvegicus (Norway rat)
Endosomal Sorting Complex Required For Transport (ESCRT)	Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4B Charged multivesicular body protein 4c Charged multivesicular body protein 5 Charged multivesicular body protein 6 Charged multivesicular body protein 7 Hepatocyte growth factor-regulated tyrosine kinase substrate Multivesicular body subunit 12A Multivesicular body subunit 12B Polyubiquitin-B Polyubiquitin-C Signal transducing adapter molecule 2 Signal transducing adaptor molecule Tumor susceptibility gene 101 protein Ubiquitin B-like Ubiquitin-associated protein 1 Ubiquitin-ribosomal protein eS31 fusion protein VPS37B subunit of ESCRT-I VPS37C subunit of ESCRT-I VPS37D subunit of ESCRT-I Vacuolar protein sorting-associated protein 28 homolog Vacuolar protein sorting-associated protein 4A Vacuolar protein-sorting-associated protein 25 Vacuolar protein-sorting-associated protein 36 Vacuolar-sorting protein SNF8 Vesicle trafficking 1 vesicle-fusing ATPase	A0A8I5ZP83 A0A8I5ZY10 A0A8I6A5Y0 A0A8I6A5Y3 A0A8I6AB52 A0A8I6ABB8 A0A8I6ACY9 A0A8I6AQ75 A0A8I6GH80 B2GV76 B5DEN9 B5DF55 B5DFF4 D4A7H9 P0C0A1 P0C0A2 P0CG51 P62982 Q4QQV8 Q569C1 Q5RK19 Q5XHY7 Q5XIS7 Q63429 Q6IRE4 Q6P777 Q793F9 Q8CGS4 Q9JJ50	Chmp2a Chmp2b Chmp3 Chmp4b Chmp4c Chmp5 Chmp6 Chmp7 Eap20 Eap30 Eap45 Fam125a Hgs Hrs Hrs2 LOC100360645 Mvb12a Mvb12b NEWGENE_1309258 Rps27a Snf8 Stam Stam2 Tsg101 Uba80 Ubap1 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vps24 Vps25 Vps28 Vps36 Vps37b Vps37c Vps37d Vps4a Vps4b Vta1 vps4-A	Rattus norvegicus (Norway rat)
Association of TriC/CCT with target proteins during biosynthesis	Chaperonin containing TCP1 subunit 6B Sphingosine kinase 1 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta	A0A8I6AR12 D4ACB8 F7ELS2 P28480 Q5XIM9 Q68FQ0 Q6AYJ7 Q6P502 Q7TPB1 Q91V26	Cct1 Cct2 Cct3 Cct4 Cct5 Cct6a Cct6b Cct7 Cct8 Ccta Cctb LOC363658 Sphk1 Tcp1	Rattus norvegicus (Norway rat)
Metal ion SLC transporters	Ceruloplasmin Hephaestin High affinity copper uptake protein 1 Natural resistance-associated macrophage protein 1 Natural resistance-associated macrophage protein 2 Solute carrier family 30, member 10 Solute carrier family 40 member 1 Solute carrier family 41 member Solute carrier family 41 member	D3ZJB7 D3ZM22 D4A7D4 O54902 P13635 P70553 Q920H8 Q923U9 Q9JK41	Bcg Copt1 Cp Ctr1 Dct1 Dmt1 Fpn1 Fpt1 Heph Nramp1 Nramp2 Slc11a1 Slc11a2 Slc30a10 Slc31a1 Slc40a1 Slc41a1 Slc41a2	Rattus norvegicus (Norway rat)
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein C Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein T Centromere protein U Centromere protein W Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 Histone-binding protein RBBP7 Holliday junction recognition protein Kinetochore scaffold 1 MIS18 binding protein 1 Nucleophosmin Opa interacting protein 5 Protein Mis18-alpha RB binding protein 4, chromatin remodeling factor Remodeling and spacing factor 1 RuvB-like 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	A0A0G2JXI9 A0A0G2K615 A0A1W2Q6F6 A0A8I5ZQQ5 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A3Y0 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AQI0 A0A8I6AWT3 A0A8I6G659 A1L1L1 A9UMV8 B2RZC4 D3Z896 D3ZGQ8 D3ZKM9 D3ZVK7 D3ZXP3 D4A1W1 D4A9X9 D4AC25 D4ACM0 E9PSW8 F1M389 G3V9C7 M0RBQ5 P0CC09 P13084 P60123 P62804 Q00729 Q3ZAU7 Q4V8G7 Q561R1 Q5U1Z7 Q5U2W4 Q63517 Q66H02 Q71UF4	Cenpc Cenpc1 Cenph Cenpi Cenpk Cenpl Cenpm Cenpn Cenpo Cenpp Cenpq Cenpr Cenpt Cenpu Cenpw Cug2 ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Fshprh1 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist4 Hist4h4 Hjurp Itgb3bp Knl1 LOC100365043 LOC100910200 LOC120097726 LOC679342 LOC681185 LOC684797 Lrpr1 Mis18a Mis18bp1 Mlf1ip Npm1 Nrif3 Oip5 Rbbp4 Rbbp7 Rsf1 Ruvbl1 Smarca5 Th2b Tip49 Tip49a	Rattus norvegicus (Norway rat)
Regulation of TP53 Activity through Association with Co-factors	Cellular tumor antigen p53 PHD finger protein 20 POU domain, class 4, transcription factor 1 POU domain, class 4, transcription factor 2 Protein phosphatase 1, regulatory subunit 13 like Protein phosphatase 1, regulatory subunit 13B RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tumor protein 63 Tumor protein p53 binding protein, 2 Tumor protein p73 Zfp385a protein	A0A8I6A8S6 A0A8I6AMB5 B2RYC6 D3ZQB7 D4AA88 F1LW07 G3V7L5 P10361 P20266 P47196 P47197 Q63484 Q9JJP6	Akt1 Akt2 Akt3 Brn-3 Brn3 Brn3a Brn3b Ket P53 P63 Phf20 Pou4f1 Pou4f2 Ppp1r13b Ppp1r13l Tp53 Tp53bp2 Tp63 Tp73 Tp73l Trp63 Zfp385a	Rattus norvegicus (Norway rat)
RUNX3 regulates CDKN1A transcription	Cellular tumor antigen p53 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor Transforming growth factor beta-1 proprotein Zinc finger homeobox 3	A0A0G2K7T0 F1M4Q6 O70437 P10361 P17246 P84025	Madh3 Madh4 P53 Runx3 Smad3 Smad4 Tgfb1 Tp53 Zfhx3	Rattus norvegicus (Norway rat)
Stabilization of p53	Cellular tumor antigen p53 E3 ubiquitin-protein ligase Mdm2 PHD finger protein 20 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Serine-protein kinase ATM Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I6A5Y3 A0A8I6G5V3 D3ZQB7 D4ACL8 P0CG51 P10361 P62982 Q5XIN1 Q63429	Atm LOC100360645 Mdm2 Mdm4 Mdmx P53 Phf20 Rps27a Tp53 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Oncogene Induced Senescence	Cellular tumor antigen p53 Cyclin dependent kinase inhibitor 2D Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 DNA-binding protein inhibitor ID-1 E3 ubiquitin-protein ligase Mdm2 ETS proto-oncogene 2, transcription factor Ets2 repressor factor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Protein C-ets-1 Protein Mdm4 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I5ZS11 A0A8I6A5Y3 A0A8I6A9F0 A0A8I6G5V3 F1MA87 P0CG51 P10361 P21708 P35426 P41135 P41156 P55272 P62982 P63086 Q5XIN1 Q63429 Q6P4Z7	Cdk4 Cdk6 Cdkn2b Cdkn2d Erf Erk1 Erk2 Ets-1 Ets1 Ets2 Id-1 Id1 Ink4 LOC100360645 Mapk Mapk1 Mapk3 Mdm2 Mdm4 Mdmx P53 Prkm1 Prkm3 Rps27a Tp53 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Oxidative Stress Induced Senescence	Cellular tumor antigen p53 Chromobox 2 Chromobox 4 Chromobox 6 Chromobox 8 Cyclin dependent kinase inhibitor 2D Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Dual specificity mitogen-activated protein kinase kinase 7 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Embryonic ectoderm development Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 MAPK activated protein kinase 5 Mapk11 protein Misshapen-like kinase 1 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Polyhomeotic homolog 1 Polyhomeotic homolog 2 Polyhomeotic homolog 3 Polyubiquitin-B Polyubiquitin-C Protein Mdm4 Protein c-Fos RB binding protein 4, chromatin remodeling factor SUZ12 polycomb repressive complex 2 subunit Scm polycomb group protein like 2 Thioredoxin Transcription factor Jun Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein [histone H3]-trimethyl-L-lysine(27) demethylase mitogen-activated protein kinase kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase mitogen-activated protein kinase kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0G2JXI9 A0A0G2K2B0 A0A0G2K490 A0A8I5Y785 A0A8I5ZLV4 A0A8I5ZMG5 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A5Y3 A0A8I6A7P3 A0A8I6ACN6 A0A8I6AEL0 A0A8I6AFH2 A0A8I6AFW8 A0A8I6AHM8 A0A8I6AIG5 A0A8I6AQI0 A0A8I6AWT3 A0A8I6G5V3 A0A8I6G659 A0A8J8YPE2 A9UMV8 B5DFE2 D3ZJ08 D3ZRL8 D3ZVK7 D3ZXP3 D4A0M3 D4A3U7 D4ACM0 F1LN87 F1LP90 F1MA87 G3V9C7 M0R7E7 M0RBQ5 M0RE14 P0CC09 P0CG51 P10361 P11232 P12841 P17325 P21708 P35426 P49185 P49186 P49187 P55272 P62804 P62982 P63086 P70618 P84245 Q00729 Q4KLY4 Q4KSH7 Q5XIN1 Q63429 Q66H84 Q6LED0 Q6MGB6 Q6P4Z7 Q71UF4 Q80ZF4 Q925D6 S4VP54	Cbx2 Cbx4 Cbx6 Cbx8 Cdk4 Cdk6 Cdkn2b Cdkn2d Csbp1 Csbp2 ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Eed Erk1 Erk2 Ezh2 Fos H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Ink4 Jnk1 Jnk2 Jnk3 Jun Kdm6b LOC100360645 LOC100365043 LOC100910200 LOC120097726 LOC684797 Map2k3 Map2k4 Map2k6 Map2k7 Map3k5 Map4k4 Map4k6 Mapk Mapk1 Mapk10 Mapk11 Mapk14 Mapk3 Mapk8 Mapk9 Mapkapk2 Mapkapk3 Mapkapk5 Mdm2 Mdm4 Mdmx Mink Mink1 Mkk6 P53 Phc1 Phc2 Phc3 Prkm1 Prkm10 Prkm3 Prkm8 Prkm9 Rbbp4 Rbbp7 Ring1 Ring1b Rjg-9 Rnf1 Rnf2 Rps27a Scml2 Suz12 Th2b Tnik Tp53 Txn Txn1 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	Cell division cycle protein 20 homolog Mitotic arrest deficient 2 like 1	D4ACM2 Q62623	Cdc20 Mad2l1	Rattus norvegicus (Norway rat)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	Cell division cycle 34, ubiqiutin conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme N-terminal E2 ubiquitin-conjugating enzyme Polyubiquitin-B Polyubiquitin-C Ubiquitin B-like Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase isozyme L3 Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 Q2 Ubiquitin-conjugating enzyme E2 B Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 G1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-conjugating enzyme E2 Z Ubiquitin-conjugating enzyme E2A Ubiquitin-conjugating enzyme E2R 2 Ubiquitin-like modifier activating enzyme 6 Ubiquitin-like modifier-activating enzyme 1 Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A8I5YBM5 A0A8I6A356 A0A8I6A5Y3 A0A8I6A8J6 A0A8J8Y4N8 B0BMY6 B5DFI8 D3Z8W5 D3ZDK2 D3ZUW6 D3ZVQ0 D4A1G2 D4A453 D4A8H3 F1M3L4 F7F5A1 G3V6M7 M0R4P9 M0R6B6 P0CG51 P62255 P62839 P62982 P63149 Q3B7D1 Q4VSI4 Q5U300 Q63429 Q91Y78	AABR07041109.1 Cdc34 Fam105b Hausp LOC100360645 LOC100362554 LOC100366017 LOC64038 NEWGENE_1308361 Otulin Rad6b Rps27a Uba1 Uba6 Uba80 Ubb Ubbl1 Ubc Ubc4 Ubc7 Ubcep1 Ubch4 Ubch5b Ubcl1 Ube1 Ube2a Ube2b Ube2c Ube2d1 Ube2d2 Ube2e1 Ube2e3 Ube2g Ube2g1 Ube2g2 Ube2h Ube2k Ube2l3 Ube2q2 Ube2r2 Ube2s Ube2t Ube2w Ube2z Uchl3 Usp5 Usp7	Rattus norvegicus (Norway rat)
G beta:gamma signalling through CDC42	Cell division control protein 42 homolog Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Rho guanine nucleotide exchange factor 6 Serine/threonine-protein kinase PAK 1	A0A8I6AF64 A0A8I6GAY3 A0A8I6GLD4 D4AAI1 F2Z3T8 G3V8K2 O35353 P35465 P43425 P52287 P54311 P54313 P61954 P62882 P63077 P63219 Q5XXR3 Q8CFN2	Arhgef6 Cdc42 Gnb1 Gnb2 Gnb3 Gnb4 Gnb5 Gng10-ps1 Gng11 Gng12 Gng3 Gng4 Gng5 Gng5-ps4 Gng7 Gng8 Gng9 Gngt1 Gngt11 Gngt5 Gngt7 Gngt9 Pak1	Rattus norvegicus (Norway rat)
DCC mediated attractive signaling	Cell division control protein 42 homolog Cytoplasmic protein Focal adhesion kinase 1 Netrin receptor DCC Proto-oncogene tyrosine-protein kinase Src Ras-related C3 botulinum toxin substrate 1 Triple functional domain protein Tyrosine-protein kinase Fyn	B2RZ33 F1M0Z1 O35346 Q62844 Q63155 Q6RUV5 Q8CFN2 Q9WUD9	Cdc42 Dcc Fak Fak1 Fyn Nck1 Ptk2 Rac Rac1 Src Trio	Rattus norvegicus (Norway rat)
Ligand-receptor interactions	Cell adhesion molecule-related/down-regulated by oncogenes Hedgehog protein Hedgehog protein Hedgehog-interacting protein Patched Sonic hedgehog protein	D3ZGL3 F1LP42 G3V7Y0 O35158 Q63673 Q6UY90	Cdo Cdon Dhh Hhip Ihh Ptch Ptch1 Shh Vhh-1	Rattus norvegicus (Norway rat)
DSCAM interactions	Cell adhesion molecule DSCAM DS cell adhesion molecule-like 1	D3ZPL7 Q8VHZ8	Dscam Dscaml1	Rattus norvegicus (Norway rat)
Nectin/Necl trans heterodimerization	Cell adhesion molecule 1 Cell adhesion molecule 3 Nectin cell adhesion molecule 1 Nectin cell adhesion molecule 2 Nectin cell adhesion molecule 3 Nectin cell adhesion molecule 4	A0A8I5YBQ6 A0A8I5ZU75 F1LNP8 Q1WIM3 Q5FVC5 Q6AYP5	Cadm1 Cadm3 Igsf4b Necl1 Nectin1 Nectin2 Nectin3 Nectin4 Pvrl1 Pvrl2 SynCam1	Rattus norvegicus (Norway rat)
Other semaphorin interactions	Cd72 molecule Plexin A1 Plexin C1 Plexin D1 Plexin-B3 Receptor-type tyrosine-protein phosphatase C Semaphorin 3E Semaphorin 4A Semaphorin 4D Semaphorin 6D Semaphorin 7A (John Milton Hagen blood group) Semaphorin-5A TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 2	A0A0G2JZC4 A0A8I5ZKT8 A0A8I6AGW9 A0A8I6G5Q1 D3Z8E2 D3ZLH5 D3ZQP6 D3ZTD8 D3ZZ89 D4AA77 F7F3I7 P04157 Q5BK59 Q6X9T7	Cd72 Dap12 Plxna1 Plxnb3 Plxnc1 Plxnd1 Ptprc Sema3e Sema4a Sema4d Sema5a Sema6d Sema7a Trem2 Tyrobp	Rattus norvegicus (Norway rat)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Ccnk protein Cyclin T2 Cyclin-C Cyclin-T1 Cyclin-dependent kinase 8 Cyclin-dependent kinase 9 E2F transcription factor 4 Furin Menin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Polyubiquitin-B Polyubiquitin-C RING-type E3 ubiquitin transferase Retinoblastoma-like protein 1 Transcription factor E2F5 (Fragment) Transcription factor Sp1 Transcription factor Transcription factor Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein WW domain containing transcription regulator 1	A0A0G2JXE8 A0A0G2JXM2 A0A8I5ZYM4 A0A8I6A5Y3 A1L1L5 D3ZGL6 D3ZS28 D4A9T1 D4A9V4 G3V8H9 O70436 O70437 O88406 P0CG51 P21708 P23377 P39947 P62982 P63086 P84025 Q01714 Q4V7E6 Q62814 Q63429 Q641Z4 Q9WVR8	AABR07035338.1 Ccnc Ccnk Ccnt1 Ccnt2 Cdk8 Cdk9 E2f4 E2f5 Erk1 Erk2 Fur Furin LOC100360645 MGC112830 Madh2 Madh3 Madh4 Madh7 Mapk Mapk1 Mapk3 Men1 Pcsk3 Prkm1 Prkm3 Rbl1 Rnf111 Rps27a Smad2 Smad3 Smad4 Smad7 Sp1 Tfdp1 Tfdp2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Wwtr1	Rattus norvegicus (Norway rat)
Estrogen-dependent gene expression	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 Core-binding factor subunit beta Cyclic AMP-dependent transcription factor ATF-2 Cyclin-T1 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Estrogen receptor General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Growth regulating estrogen receptor binding 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Hepatocyte nuclear factor 3-alpha Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.3 Histone H3 Histone H4 Histone acetyltransferase KAT5 Histone acetyltransferase Histone deacetylase 1 Histone lysine acetyltransferase CREBBP Histone-arginine methyltransferase CARM1 Lysine-specific histone demethylase Nuclear receptor coactivator 3 (Fragment) Nuclear receptor coactivator Nuclear receptor interacting protein 1 Nuclear receptor subfamily 5 group A member 2 POU domain, class 2, transcription factor 1 (Fragment) Peptidyl-prolyl cis-trans isomerase FKBP4 Probable ATP-dependent RNA helicase DDX5 Progesterone receptor Prostaglandin E synthase 3 Protein arginine N-methyltransferase 1 Protein c-Fos RNA polymerase II subunit C RNA polymerase II subunit D RNA polymerase II subunit I RNA polymerase II subunit J Runt-related transcription factor 1 TATA-box-binding protein Transcription factor Jun Transcription factor YY1 Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transducin-like enhancer protein 3 Zinc finger protein 217 [histone H3]-trimethyl-L-lysine(9) demethylase histone acetyltransferase	A0A0G2JVK0 A0A0G2JXI9 A0A0G2JXM2 A0A0G2K736 A0A8I5Y222 A0A8I5ZKV9 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A2X2 A0A8I6A7P3 A0A8I6A9T0 A0A8I6AFW8 A0A8I6APA0 A0A8I6AWT3 A0A8I6AXL7 A0A8I6G641 A0A8I6G659 A0A8I6GMB2 A9UMV8 B0BNE2 D3ZJ08 D3ZQI0 D3ZVK7 D3ZXP3 D4A5A6 D4AB75 D4ACM0 F1LW89 G3V672 G3V8Y5 G3V9C7 M0RB75 M0RBH0 M0RBQ5 M0RCG9 O08949 O08950 O88828 P06211 P0CC09 P12841 P17325 P23512 P31503 P34058 P62489 P62804 P82995 P83868 P84245 Q00729 Q00969 Q01750 Q4AE70 Q4QQW4 Q5EB90 Q63009 Q63046 Q63449 Q641Z4 Q6AY96 Q6JHU9 Q6LED0 Q8CHJ4 Q99MK2 Q9EPU2 Q9JIT3 Q9QVC8 Q9QWM1	AC109542.1 Aib1 Aml1 Atf2 Carm1 Cbfa2 Cbfb Cbp Ccnt1 Cdk9 Cited1 Crebbp Ddx5 ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Ep300 Esp3 Esr Esr1 Estr Fkbp4 Fkbp52 Fos Foxa1 Greb1 Gtf2a1 Gtf2a2 Gtf2f1 Gtf2f2 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H3-3b H3.3b H3c13 H3f3b H4c16 H4c2 H4f16 H4ft Hdac1 Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist2h3c2 Hist4 Hist4h4 Hnf3a Hrmt1l2 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Htatip Jun Kat2b Kat5 Kdm1a Kdm4b LOC100365043 LOC100910200 LOC120097726 LOC120098305 LOC684797 Ncoa1 Ncoa3 Nr3a1 Nr3c3 Nr5a2 Nrip1 Oct-1 Otf-1 Otf1 Pgr Polr2a Polr2b Polr2c Polr2d Polr2e Polr2f Polr2g Polr2i Polr2j Pou2f1 Prmt1 Prmt4 Ptges3 RGD1564091 Rap30 Rjg-9 Runx1 Tbp Tcf-3a Tcf3a Tebp Th2b Tip60 Tip60b Tle3 Yy1 Zfp217 yy1	Rattus norvegicus (Norway rat)
NOSTRIN mediated eNOS trafficking	Caveolin-1 Dynamin-2 Nitric oxide synthase 3 Nostrin	P39052 P41350 Q5I0D6 Q62600	Cav Cav1 Dnm2 Dyn2 Nos3 Nostrin	Rattus norvegicus (Norway rat)
RHOH GTPase cycle	Caveolin-1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Fam91a1 protein Glioblastoma amplified sequence Junction plakoglobin Methionine synthase NSFL1 cofactor p47 Neutral amino acid transporter B(0) Proto-oncogene tyrosine-protein kinase LCK Ragulator complex protein LAMTOR1 Ral GTPase-activating protein subunit alpha-1 Ras homolog family member H Ras-related protein Rab-7a Rho GDP dissociation inhibitor beta Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 5 Sodium bicarbonate cotransporter 3 Stomatin Transferrin receptor protein 1 Transitional endoplasmic reticulum ATPase Transmembrane protein 59 Tubulin alpha-1B chain Tyrosine-protein kinase CSK Tyrosine-protein kinase Uveal autoantigen with coiled-coil domains and ankyrin repeats Vang-like protein Vesicle-associated membrane protein 3 WD repeat domain 11 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A8I5ZRJ5 A0A8I5ZV26 A0A8I5ZXI2 A0A8I6AHV6 B2GV15 B2RYP3 B5DF62 D3Z9L5 D3ZGS5 D3ZJ25 D3ZKC8 D3ZQ51 D3ZTP3 D4A280 O35987 O55007 P09527 P32577 P35465 P41350 P46462 P63025 Q01621 Q5BJZ5 Q5RK08 Q5XI73 Q62868 Q63644 Q64303 Q6P0K8 Q6P791 Q6P9V9 Q99376 Q9R1N3 Q9Z2Q4	Arhgdia Arhgdib Arhgdig Cav Cav1 Csk Dbt Fam91a1 Garnl1 Gbas Jup LOC498174 Lamtor1 Lck Mtr Nbc Nbc2 Nbc3 Nbcn1 Nipsnap2 Nsfl1c Pak1 Pak2 Pak4 Pak5 Pak6 Pak7 Pg RGD1310313 Rab7 Rab7a Ralgapa1 Rhoh Rock1 Rock2 Slc1a5 Slc4a7 Stom Syb3 Tfrc Tmem59 Trfr Tuba1b Tuba2 Tulip1 Uaca Vamp3 Vangl1 Vcp Wdr11 Zap70	Rattus norvegicus (Norway rat)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Procathepsin L Serpin family B member 13 Similar to Cathepsin L precursor (Major excreted protein) (MEP)	D3ZKA0 D3ZKC3 O35186 P07154	Cts7l2 Ctsk Ctsl Ctsl1 Ctsll3 RGD1308751 Serpinb13	Rattus norvegicus (Norway rat)

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