GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **426 - 450** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	Inhibitor of nuclear factor kappa B kinase subunit epsilon Interferon regulatory factor 3 Interferon regulatory factor 7 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 Optineurin Polyubiquitin-B Polyubiquitin-C TANK-binding kinase 1 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 TNF receptor-associated factor TRAF family member-associated NFKB activator Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2K130 A0A0G2K7X2 A0A8I6A5Y3 D3ZUM2 D3ZXR7 D4A5E7 D4A7D3 F7EXX5 M0RA08 P0CG51 P41499 P62982 Q3SWU2 Q56DL5 Q63429 Q63691 Q8R5M4 Q9QX05	Cd14 Ikbke Irf3 Irf7 LOC100360645 Ly96 Optn Plin3 Ptpn11 Rps27a Sarm1 Tank Tbk1 Ticam1 Ticam2 Tlr4 Traf3 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
Gamma-carboxylation of protein precursors	Coagulation factor IX Coagulation factor VII Coagulation factor X Osteocalcin Protein Z, vitamin K-dependent plasma glycoprotein Prothrombin Vitamin K-dependent gamma-carboxylase Vitamin K-dependent protein C Vitamin K-dependent protein S	G3V8K8 O88496 P04640 P16296 P18292 P31394 P53813 Q63207 Q8K3U6	Bglap Bglap2 Cf9 F10 F2 F7 F9 Ggcx Proc Pros Pros1 Proz	Rattus norvegicus (Norway rat)
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type oligopeptide transporter ABCB9 ATP binding cassette subfamily A member 8 ATP binding cassette subfamily B member 5 ATP binding cassette subfamily C member 10 ATP-binding cassette sub-family C member 2 ATP-binding cassette sub-family C member 3 ATP-binding cassette sub-family C member 5 ATP-binding cassette sub-family C member 6 ATP-binding cassette sub-family C member 9 ATP-binding cassette sub-family F member 1 ATP-binding cassette subfamily C member 4 ATP-dependent translocase ABCB1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Derlin Derlin Derlin E3 ubiquitin-protein ligase RNF185 E3 ubiquitin-protein ligase RNF5 Endoplasmic reticulum lectin Erlin-2 Erlin Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3, X-linked Multidrug resistance-associated protein 1 Phosphatidylcholine translocator ABCB4 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein OS-9 Protein sel-1 homolog 1 Transitional endoplasmic reticulum ATPase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A2D0 A0A8I6A5Y3 A0A8I6AMH0 A0A8I6G5P0 B0BN93 B1WBY7 B5DEH2 D3ZAE9 D3ZF97 D3ZX04 D4AEL4 F1LMQ3 F1LMZ8 F1M3J4 F1M6I7 F7FGV7 G3V6W6 G3V8G2 O88269 O88563 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P34158 P40112 P40307 P43245 P46462 P48004 P60901 P62193 P62198 P62982 P68101 P70673 P81795 Q08201 Q4FZT9 Q4KM35 Q4V8E2 Q568Y3 Q5M807 Q5RKH6 Q5RKH9 Q5XIC6 Q5XIU5 Q63120 Q63347 Q63429 Q63563 Q63569 Q63570 Q63797 Q63798 Q6MG08 Q80Z70 Q8CG09 Q9JHW0 Q9QYJ4 Q9QYM0 Q9WTV5 Q9Z2X3	Abc50 Abca8 Abcb1 Abcb4 Abcb5 Abcb9 Abcc1 Abcc10 Abcc2 Abcc3 Abcc4 Abcc5 Abcc6 Abcc7 Abcc9 Abcf1 Cftr Cmoat Cmoat2 Cmrp Derl1 Derl2 Derl3 Eif2a Eif2g Eif2s1 Eif2s2 Eif2s3 Eif2s3x Erlec1 Erlin1 Erlin2 Kcnj11 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mdr1 Mdr1b Mdr2 Mecl1 Mlp1 Mlp2 Mrp1 Mrp2 Mrp3 Mrp4 Mrp5 Mrp6 Mss1 Os9 Pgp3 Pgy1 Pgy2 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ring12 Rnf185 Rnf5 Rps27a Sel1h Sel1l Spfh2 Sug1 Sur2 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vcp	Rattus norvegicus (Norway rat)
Propionyl-CoA catabolism	Metabolism of cobalamin associated A Methylmalonyl CoA epimerase Methylmalonyl-CoA mutase, mitochondrial Propionyl-CoA carboxylase alpha chain, mitochondrial Propionyl-CoA carboxylase beta chain, mitochondrial	A0A8I5YC26 D3ZKG1 D3ZNY3 P07633 P14882	LOC100361295 Mcee Mmaa Mmut Mut Pcca Pccb	Rattus norvegicus (Norway rat)
PI3K Cascade	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated binding protein 1 GRB2-associated-binding protein 2 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphoinositide 3-kinase regulatory subunit 4 Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type 11 receptor protein-tyrosine kinase	A0A0G2JW59 A0A0G2K210 A0A0G2K344 A0A8I6B5D5 D3Z8T6 D3ZAL7 D4A244 F1LSG7 F1LSQ8 F1MAL5 M0RAA8 O54769 O88182 O88763 P0C0R5 P13109 P35570 P36364 P41499 P48807 P61149 P62994 P63076 P70492 Q02195 Q04589 Q498D6 Q63787 Q63788 Q8R5L5 Q8R5L9 Q8VI79 Q8VI81 Q8VI82 Q9EQH1 Q9EST9 Q9Z1L0 Q9Z2Y9	Ash FGF15 FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-7 Fgf-9 Fgf1 Fgf10 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr1 Fgfr2 Fgfr3 Fgfr4 Flg Flt3 Frs2 Gab1 Gab2 Grb2 Irs-1 Irs1 Irs2 Kgf Kl Klb Pik3c3 Pik3ca Pik3cb Pik3r1 Pik3r2 Pik3r4 Ptpn11 Tlr9 Vps34	Rattus norvegicus (Norway rat)
Attachment of GPI anchor to uPAR	GPI inositol-deacylase GPI transamidase component PIG-S Glycosylphosphatidylinositol anchor attachment 1 Phosphatidylinositol glycan anchor biosynthesis class U protein Phosphatidylinositol glycan anchor biosynthesis, class T Urokinase plasminogen activator surface receptor	A0A8I6GIH3 F7EVW7 P49616 Q5XI31 Q765A7 Q8CHJ1	Cdc91l1 Gpaa1 Pgap1 Pigs Pigt Pigu Plaur	Rattus norvegicus (Norway rat)
Postmitotic nuclear pore complex (NPC) reformation	AT hook containing transcription factor 1 GTP-binding nuclear protein Ran LOC683983 protein Nuclear envelope pore membrane protein POM 121 Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup93 Nuclear pore complex protein Nup98-Nup96 Nucleoporin 133 Nucleoporin 160 Nucleoporin 205 Nucleoporin 37 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Protein SEC13 homolog RAN GTPase activating protein 1 Regulator of chromosome condensation SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	A0A0G2K160 A0A0G2K3M4 A0A0G2K5R3 A0A8I5ZJ67 A0A8I5ZU07 B0BNB5 D3Z8B2 D3ZBL6 F1LRC6 P37199 P49793 P52590 P52591 P62828 P63281 Q4QQS8 Q5I0H3 Q5XFW8 Q66HC5 Q68FY1 Q6AXN4	Ahctf1 LOC683983 Ndc1 Nup107 Nup121 Nup133 Nup155 Nup160 Nup188 Nup205 Nup35 Nup37 Nup43 Nup53 Nup85 Nup93 Nup98 Pcnt1 Pom121 Ran Rangap1 Rcc1 Sec13 Sec13l1 Sumo1 Tmem48 Ubce9 Ube2i	Rattus norvegicus (Norway rat)
G2/M DNA damage checkpoint	ATR interacting protein BRCA1 interacting helicase 1 BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein homolog Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint control protein Cellular tumor antigen p53 Checkpoint protein DNA 3'-5' helicase DNA 3'-5' helicase DNA endonuclease RBBP8 DNA repair protein RAD50 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase II binding protein 1 DNA topoisomerase Double-strand break repair protein MRE11 E3 ubiquitin-protein ligase RNF168 E3 ubiquitin-protein ligase RNF8 Exonuclease 1 HECT-type E3 ubiquitin transferase Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 Histone acetyltransferase KAT5 Lys-63-specific deubiquitinase BRCC36 Mediator of DNA damage checkpoint protein 1 Nibrin Nuclear receptor binding SET domain protein 2 Protein inhibitor of activated STAT, 4 RAD1 checkpoint DNA exonuclease RAD17 checkpoint clamp loader component RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ mediated genome instability 2 RecQ-mediated genome instability protein 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 32 kDa subunit Replication protein A subunit Replication protein A3 Serine-protein kinase ATM Serine/threonine-protein kinase ATR Serine/threonine-protein kinase Chk1 Tumor protein p53 binding protein 1 Ubiquitin-conjugating enzyme E2 variant 2	A0A0G2JUC9 A0A0G2JXI9 A0A0G2K475 A0A0G2K4W8 A0A8I5ZSA8 A0A8I6A014 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6GFZ6 B1WC58 B2RYM5 B2RYR0 B4F778 B5DF29 B5DFF9 D3Z822 D3ZC52 D3ZG52 D3ZHX4 D3ZNA8 D3ZQW1 D3ZXM2 D3ZXP3 D4A4M3 D4A6J4 D4A845 D4A9J4 D4ACL8 E9PTL1 F1LTH9 F1M842 G3V9C7 M0RBQ5 O54952 P10361 P62804 Q00729 Q499V3 Q4KLN8 Q5I0F1 Q5M830 Q5PQK4 Q5U2M8 Q5XIJ6 Q63528 Q641W4 Q6AY26 Q6P7Q1 Q7M767 Q7TP21 Q91ZN7 Q99MK2 Q9JIL8 Q9JIL9 Q9JIM0 Q9QZH2	ABRAXAS1 Abra1 Atm Atr Atrip Babam1 Babam2 Bard1 Blm Brca1 Brcc3 Brcc36 Bre Brip1 Ccdc98 Chek1 Chk1 Ctip Dna2 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 Exo1 Fam175a H2afx H2ax H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Herc2 Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist4 Hist4h4 Htatip Hus1 Kat5 LOC100365043 LOC100910200 LOC684797 Mdc1 Merit40 Mms2 Mre11 Mre11a Nba1 Nbn Nbs1 Nsd2 P53 Pias4 RGD1564788 Rad1 Rad17 Rad50 Rad9a Rad9b Rap80 Rbbp8 Rfc2 Rfc3 Rfc4 Rfc5 Rhno1 Rmi1 Rmi2 Rnf168 Rnf8 Rpa1 Rpa2 Rpa3 Th2b Tip60 Tip60b Top3a Topbp1 Tp53 Tp53bp1 Ube2v2 Uev2 Uimc1 Whsc1 Wrn	Rattus norvegicus (Norway rat)
Nitric oxide stimulates guanylate cyclase	Nitric oxide synthase 1 Nitric oxide synthase 3 Nitric oxide synthase, inducible	P29476 Q06518 Q62600	Bnos Nos1 Nos2 Nos3	Rattus norvegicus (Norway rat)
Inositol transporters	Proton myo-inositol cotransporter Sodium/myo-inositol cotransporter 2 Solute carrier family 5 member 3	A0A8I6GM79 Q921A2 Q9Z1F2	Kst1 Slc2a13 Slc5a11 Slc5a3 Smit2	Rattus norvegicus (Norway rat)
Metabolism of polyamines	Ornithine decarboxylase S-adenosylmethionine decarboxylase proenzyme Spermidine synthase Spermine synthase, pseudogene 2	A0A8I6AVR1 M0RCX8 P09057 P17708	Amd1 Odc Odc1 Sms Sms-ps2 Srm	Rattus norvegicus (Norway rat)
Attenuation phase	DnaJ heat shock protein family (Hsp40) member B1 Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock transcription factor 1 Heat shock-related 70 kDa protein 2 Histone lysine acetyltransferase CREBBP Peptidyl-prolyl cis-trans isomerase FKBP4 Prostaglandin E synthase 3 histone acetyltransferase	A0A8I6G641 D3ZUU5 F1MAF1 P0DMW0 P0DMW1 P14659 P34058 P55063 P63018 P82995 P83868 Q6JHU9 Q8K3X8 Q9QVC8	Cbp Crebbp Dnajb1 Ep300 Fkbp4 Fkbp52 Hsbp1 Hsc70 Hsc73 Hsf1 Hsp70-1 Hsp70-2 Hsp70-3 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hspc3 Hspca Hspcb Hst70 Ptges3 Tebp	Rattus norvegicus (Norway rat)
Lewis blood group biosynthesis	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 Alpha-(1,3)-fucosyltransferase 10 Alpha-(1,3)-fucosyltransferase 11 Alpha-(1,3)-fucosyltransferase 4 Alpha-(1,3)-fucosyltransferase 7 Beta-1,3-galactosyltransferase 4 Beta-1,4-N-acetyl-galactosaminyl transferase 2 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Galactoside alpha-(1,2)-fucosyltransferase 2 Hexosyltransferase Hexosyltransferase Hexosyltransferase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A8I6AAQ3 D3ZPD8 D4A950 D4AB20 M0R3S4 O88178 P61131 P61943 Q02734 Q10984 Q5F2L1 Q62994 Q68FV3 Q712G6 Q99JB3	B3galt1 B3galt2 B3galt4 B3galt5 B4galnt2 Ftb Fut10 Fut11 Fut2 Fut4 Fut7 Fut9 Rfuc-t Sec1 Siat10 Siat4c Siat6 St3gal3 St3gal4 St3gal6 St6galnac6	Rattus norvegicus (Norway rat)	G39211DH G83633HB G90387AM G98173LG
Factors involved in megakaryocyte development and platelet production	A-kinase anchor protein 1, mitochondrial A-kinase anchoring protein 10 Capping protein regulator and myosin 1 linker 1 Cbx5 protein Cell division control protein 42 homolog DNA repair protein RAD51 homolog 3 Dedicator of cyto-kinesis 3 Dedicator of cytokinesis 10 Dedicator of cytokinesis 11 Dedicator of cytokinesis 2 Dedicator of cytokinesis 4 Dedicator of cytokinesis 5 Dedicator of cytokinesis 6 Dedicator of cytokinesis 7 Dedicator of cytokinesis 8 EH domain-containing protein 1 EH domain-containing protein 2 EH domain-containing protein 3 Endothelial transcription factor GATA-2 Erythroid transcription factor F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit beta GTP High mobility group 20 B Histone H3.1 Histone H3.3 Histone H3 Histone deacetylase 1 Histone deacetylase 2 Inositol-tetrakisphosphate 1-kinase Jumonji domain containing 1C Lysine-specific histone demethylase MAF bZIP transcription factor F Mitofusin-1 Mitofusin-2 PHD finger protein 21A RAD51 paralog B REST corepressor 1 Rabenosyn, RAB effector Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-5A SH2B adapter protein 1 SH2B adapter protein 2 Transcription factor GATA-4 Transcription factor GATA-6 Transcription factor MafG Transcription factor NF-E2 45 kDa subunit Tyrosine-protein kinase JAK2 Vacuolar protein sorting-associated protein 45 Zinc finger protein, multitype 1 Zinc finger protein, multitype 2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A0A0G2JV16 A0A0G2K3H2 A0A0G2K736 A0A0G2K7L4 A0A8I5ZK89 A0A8I5ZN85 A0A8I5ZNR8 A0A8I5ZRT6 A0A8I5ZYE0 A0A8I6A829 A0A8I6ABZ8 A0A8I6ADN8 A0A8I6AJW0 A0A8I6ANH8 A0A8I6AW56 A0A8I6AXM6 B2GUZ5 B2RYU7 D3ZJ08 D3ZL11 D4A0R1 D4A168 D4A586 F1M4N6 F7ENH8 G3V6U0 M0R3J8 M0RC99 O08700 O88884 P09456 P12368 P12369 P27791 P29411 P43429 P46152 P46153 P68182 P81377 P84245 Q3T1K5 Q4QQW4 Q4V8H8 Q5XI32 Q62689 Q62985 Q641Z6 Q6AYT2 Q6LED0 Q6RUV5 Q76MX4 Q8CFN2 Q8R491 Q8R4Z9 Q8R500 Q924Y4 Q9Z200	Ak3 Ak3l1 Akap Akap1 Akap10 Akl3l Aps Capza1 Capza2 Capzb Carmil1 Cbx5 Cdc42 Dock10 Dock11 Dock2 Dock3 Dock4 Dock5 Dock6 Dock7 Dock8 Ehd1 Ehd2 Ehd3 Fzo1a Fzo1b Gata1 Gata2 Gata4 Gata6 H3-3b H3.3b H3c13 H3f3b Hdac1 Hdac2 Hist2h3c2 Hmg20b Itpk1 Jak2 Jmjd1c Kdm1a Maff Mafg Mfn1 Mfn2 Nfe2 Phf21a Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b Rab5a Rac Rac1 Rad51b Rad51c Rbsn Rcor1 Sh2-b Sh2b1 Sh2b2 Sh2bpsm1 Vps45 Vps45a Zfpm1 Zfpm2 Zfyve20	Rattus norvegicus (Norway rat)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor IX Coagulation factor VII Coagulation factor X Tissue factor pathway inhibitor Tissue factor	P16296 P42533 Q02445 Q63207 Q8K3U6	Cf3 Cf9 F10 F3 F7 F9 Tfpi	Rattus norvegicus (Norway rat)
VLDL clearance	Apolipoprotein B receptor Apolipoprotein B-100 Apolipoprotein C-I Apolipoprotein C-IV Very low-density lipoprotein receptor	A0A0G2K7M4 P19939 P55797 P98166 Q7TMA5	Apob Apobr Apoc1 Apoc4 Ecl Vldlr	Rattus norvegicus (Norway rat)
RUNX3 regulates WNT signaling	Catenin beta-1 Lymphoid enhancer-binding factor 1 Runt-related transcription factor Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7	A0A0G2K7T0 A0A8I5ZLY3 A0A8I5ZT78 A0A8I6A9A2 Q9QXN1 Q9WU82	Catnb Ctnnb1 Lef1 Runx3 Tcf7 Tcf7l1 Tcf7l2	Rattus norvegicus (Norway rat)
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member A2 Aldehyde dehydrogenase family 3 member B1 Aldehyde dehydrogenase Alkaline ceramidase Alkaline ceramidase Alkaline ceramidase Phospholipid phosphatase 1 Phospholipid phosphatase 2 Phospholipid phosphatase 3 Sphingosine-1-phosphate lyase 1 Sphingosine-1-phosphate phosphatase 1 Sphingosine-1-phosphate phosphatase 2	A0A8I6ADP7 A0A8I6AGX4 A0A8I6AKN2 D3ZNW4 M0R603 O08564 P30839 P97544 Q5XI42 Q8CHN6 Q8K593 Q99P55	Acer1 Acer2 Acer3 Aldh3a2 Aldh3b1 Aldh3b2 Aldh4 Lpp1 Lpp2 Lpp3 Plpp1 Plpp2 Plpp3 Ppap2a Ppap2b Ppap2c Sgpl1 Sgpp1 Sgpp2 Spl	Rattus norvegicus (Norway rat)
Transcriptional activation of mitochondrial biogenesis	Cytochrome c domain-containing protein Cytochrome c, somatic GA binding protein transcription factor subunit alpha GA binding protein transcription factor subunit beta 1 Glutamate dehydrogenase 1, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial NAD-dependent protein deacylase sirtuin-5, mitochondrial NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Propionate--CoA ligase Similar to Cytochrome c, somatic Sirtuin 3 Superoxide dismutase [Mn], mitochondrial	A0A0G2K6D8 A0A8I5XWT5 A0A8I5ZWD2 A0A8I6GJ11 D3ZXV2 D4A5L9 D4ACQ9 P07895 P10860 P56574 P62898 Q68FX9	AC128290.1 Acss2 Cycs Cycsl2 Cycsl3 Gabpa Gabpb1 Glud Glud1 Idh2 LOC690675 RGD1562558 SIRT4 Sirt3 Sirt4 Sirt5 Sod2	Rattus norvegicus (Norway rat)
Regulation of lipid metabolism by PPARalpha	DNA helicase Fatty acid-binding protein, liver Histone deacetylase 3 Histone lysine acetyltransferase CREBBP Histone-arginine methyltransferase CARM1 Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor co-repressor 2 Nuclear receptor coactivator 2 Nuclear receptor coactivator Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR-alpha SIN3 transcription regulator family member A SIN3 transcription regulator family member B SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 TBL1X/Y related 1 Transducin (beta)-like 1 X-linked Trimethylguanosine synthase	A0A096MJV7 A0A0G2JU91 A0A0G2JY80 A0A8I5ZQQ2 A0A8I6AC46 A0A8I6APA0 A0A8I6G8L9 D3ZBP2 D3ZNF4 P02692 P37230 P85107 Q05343 Q4AE70 Q6JHU9 Q6P6W3 Q9WUI9	Carm1 Cbp Chd9 Crebbp Fabp1 Hdac3 Med1 Ncoa1 Ncoa2 Ncoa6ip Ncor2 Nr1c1 Nr2b1 Pimt Ppar Ppara Prmt4 Rxra Sin3a Sin3b Smarcd3 Tbl1x Tbl1xr1 Tgs1 Tif2	Rattus norvegicus (Norway rat)
RHOG GTPase cycle	10 kDa heat shock protein, mitochondrial ADP-ribosylation factor GTPase-activating protein 3 Ankyrin repeat and LEM domain-containing protein 2 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cyto-kinesis 3 Dedicator of cytokinesis 2 Dedicator of cytokinesis 4 Dedicator of cytokinesis 5 Delta(14)-sterol reductase LBR Desmoglein 2 Emerin Engulfment and cell motility 2 Extended synaptotagmin-1 Granule associated Rac and RHOG effector 1 Guanine nucleotide exchange factor DBS IQ motif containing GTPase activating protein 2 Integrin beta-1 Intersectin-1 Kalirin Kinectin 1 LOC687105 protein MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Membrane-associated progesterone receptor component 2 Mitochondrial proton/calcium exchanger protein Mitogen-activated protein kinase kinase kinase 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Phospholipase D1 Pleckstrin homology and RhoGEF domain containing G3 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene vav RNA binding motif protein 39 Ragulator complex protein LAMTOR1 Ras homolog family member G Ras-related protein Rab-7a Rho GDP dissociation inhibitor beta Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 32 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Serine hydroxymethyltransferase Serine/threonine-protein kinase PAK 2 Starch-binding domain-containing protein 1 Synaptobrevin homolog YKT6 Syntaxin-5 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase receptor protein-tyrosine kinase	A0A0G2JVP1 A0A0G2JYR5 A0A0G2K7N9 A0A8I5ZK89 A0A8I5ZNR8 A0A8I5ZPB5 A0A8I5ZRJ5 A0A8I5ZRT6 A0A8I5ZXI2 A0A8I6A4W2 A0A8I6A9Q4 A0A8I6AEP6 A0A8I6AG90 A0A8I6AM38 A0A8I6GDA1 A0A8I6GLR6 A0A8J8XFB5 A0A8J8XIU8 A1A5P0 B2GUW2 B5DF62 D3ZA21 D3ZBN3 D3ZG43 D3ZKC8 D3ZYG0 D4A1D2 D4A8H8 D4AA32 E9PT59 F1LVW7 F1M0Z1 F1M4N6 F1MAK3 G3V982 P09527 P0CAX5 P26772 P41350 P49134 P54100 P63025 P70496 P81128 P97924 Q08851 Q32PX6 Q4KLN7 Q5EGY4 Q5FVN1 Q5U2Y3 Q5U3Z7 Q5XI73 Q5XIN6 Q5XIU9 Q62902 Q63190 Q63362 Q63406 Q63787 Q64303 Q66HA1 Q6P791 Q7TP65 Q8CFN2 Q99376 Q9EPF2 Q9WVE9 Q9Z1X1 Q9Z269	AABR07021955.1 Ankle2 Arfgap3 Arhgap1 Arhgap21 Arhgap32 Arhgap35 Arhgap5 Arhgdia Arhgdib Arhgdig Arhgef16 Arhgef26 Arhgef5 Borg5 Cav Cav1 Cdc42 Cdc42ep1 Cyfip1 Depdc1b Diaph3 Dock2 Dock3 Dock4 Dock5 Dsg2 Duo Ehsh1 Elmo2 Emd Epha2 Ergic53 Esyt1 Fam62a Garre1 Grlf1 Hapip Hspe1 Iqgap2 Itgb1 Itsn Itsn1 Kalrn Ktn1 LOC687105 Lamtor1 Lbr Lem4 Letm1 Lman1 Map3k11 Mbc2 Mcam Mcf2 Mcf2l Mlk3 Mpp7 Muc18 Ndufa5 Ndufs3 Ophn1 Ost P190A Pak2 Pak4 Pgrmc2 Pik3r1 Pld1 Plekhg3 Prex1 Rab7 Rab7a Rbm39 Rhog Shmt2 Stbd1 Stx5 Stx5a Syb3 Tfrc Trfr Trio Vamp3 Vangl1 Vapb Vav Vav1 Vav2 Vav3 Vrk2 Ykt6 p190ARHOGAP	Rattus norvegicus (Norway rat)
Reactions specific to the complex N-glycan synthesis pathway	Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-mannosidase 2 Alpha-mannosidase Carbohydrate sulfotransferase 10 Tissue alpha-L-fucosidase	A0A0G2JWG1 O54702 P17164 P28494 Q09326 Q6EV76	Chst10 Fuca Fuca1 Fut8 Gnt2 Man2a1 Man2a2 Mana2 Mgat2	Rattus norvegicus (Norway rat)	G70323CJ G82576YO
CaMK IV-mediated phosphorylation of CREB	Calcium/calmodulin-dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 2 Calcium/calmodulin-dependent protein kinase type IV Calmodulin-3	O88831 P0DP31 P13234 P97756	CaMIII Calm3 Cam3 Camc Camk4 Camkk1 Camkk2	Rattus norvegicus (Norway rat)
Type II Na+/Pi cotransporters	Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Sodium-dependent phosphate transport protein 2C	Q06496 Q8K4R8 Q9JJ09	Slc17a2 Slc34a1 Slc34a2 Slc34a3	Rattus norvegicus (Norway rat)
SHC-mediated cascade:FGFR4	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 Klotho beta SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A8I6B5D5 D3Z8T6 D4A3T0 F1LSQ8 O54769 O88182 P08644 P13109 P20171 P36364 P61149 P62994 P63076 Q04970 Q498D6 Q5M824 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	Ash FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Grb2 Hras Hras1 Klb Kras Kras2 Nras Shc1 Sos1	Rattus norvegicus (Norway rat)

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