GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **576 - 600** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
MET activates RAP1 and RAC1	Adapter molecule crk Crk-like protein Dedicator of cytokinesis 7 GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rap-1A Ras-related protein Rap-1b	A0A0G2K3H2 D3ZAL7 F1M8L9 P17945 P62836 P62994 P97523 Q5U2U2 Q62636 Q63768 Q6RUV5	Ash Crk Crkl Crko Dock7 Gab1 Grb2 Hgf Krev1 Met Rac Rac1 Rap1a Rap1b Rapgef1	Rattus norvegicus (Norway rat)
HS-GAG biosynthesis	Agrin Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Exostosin glycosyltransferase 1 Exostosin glycosyltransferase 2 Glypican 4 Glypican 5 Glypican 6 Glypican-1 Glypican-2 Glypican-3 Heparan sulfate 2-O-sulfotransferase 1 Heparan sulfate glucosamine 3-O-sulfotransferase 1 Heparan sulfate glucosamine 3-O-sulfotransferase 2 Heparan-sulfate 6-O-sulfotransferase Heparan-sulfate 6-O-sulfotransferase Heparan-sulfate 6-O-sulfotransferase Solute carrier family 35 member D2 Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 [heparan sulfate]-glucosamine N-sulfotransferase [heparan sulfate]-glucosamine N-sulfotransferase [heparan sulfate]-glucosamine N-sulfotransferase	A0A0G2KAH7 A0A8I5ZN51 A0A8I5ZUU3 A0A8I6A609 A0A8I6ACQ6 D3ZD27 D3ZD62 D3ZDL1 D3ZEK5 D3ZFR1 D3ZGJ6 D3ZTA9 D4A1T9 D4A6E6 D4ABE3 G3V7N0 G3V901 P13265 P25304 P26260 P33671 P34900 P34901 P35053 P51653 Q02353 Q642B0 Q80W66 Q9ESG5	3ost 3ost1 3ost2 Agrin Agrn Ext1 Ext2 Gpc1 Gpc2 Gpc3 Gpc4 Gpc5 Gpc6 Hs2st1 Hs3st1 Hs3st2 Hs3st3a1 Hs3st3b1 Hs3st4 Hs3st5 Hs3st6 Hs6st1 Hs6st2 Hs6st3 Hspg1 Hsst Hsst1 Ndst1 Ndst2 Ndst3 Ndst4 Sdc1 Sdc2 Sdc3 Sdc4 Slc35d2 Synd1 Synd2 Synd3 Synd4	Rattus norvegicus (Norway rat)
Effects of PIP2 hydrolysis	Diacylglycerol kinase alpha Diacylglycerol kinase beta Diacylglycerol kinase gamma Diacylglycerol kinase iota Diacylglycerol kinase theta Diacylglycerol kinase zeta Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C theta type Short transient receptor potential channel 3 Transient receptor potential cation channel, subfamily C, member 7	A0A096UWG9 D3ZEY4 D3ZSZ6 F1LQF7 F1LZW2 F1M5T2 F1MAB7 O08560 P09215 P09216 P29994 P29995 P49620 P49621 P51556 Q63269 Q64617 Q9JMI9 Q9WTQ0	Dagk Dagk1 Dagk2 Dagk3 Dagk6 Dgka Dgkb Dgkd Dgke Dgkg Dgkh Dgki Dgkk Dgkq Dgkz Insp3r Itpr1 Itpr2 Itpr3 Pkcd Pkce Pkch Pkcq Prkcd Prkce Prkch Prkcq Trpc3 Trpc7 Trrp3	Rattus norvegicus (Norway rat)
Nephrin family interactions	Cytoplasmic protein Cytoplasmic protein IQ motif containing GTPase activating protein 1 Kin of IRRE-like protein 1 Kirre like nephrin family adhesion molecule 2 Kirre like nephrin family adhesion molecule 3 Nephrin Tyrosine-protein kinase Fyn	A0A8I5ZQV3 B2RZ33 D4A3M8 D4A934 G3V7Q7 Q62844 Q6X936 Q9R044	Fyn Iqgap1 Kirrel Kirrel1 Kirrel2 Kirrel3 Nck1 Nck2 Neph1 Nphn Nphs1	Rattus norvegicus (Norway rat)
Repression of WNT target genes	C-terminal-binding protein 1 C-terminal-binding protein 2 Lymphoid enhancer-binding factor 1 TLE family member 1, transcriptional corepressor TLE family member 2, transcriptional corepressor Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7 Transducin-like enhancer protein 3 Transducin-like enhancer protein 4	A0A0G2K109 A0A8I5ZLY3 A0A8I5ZT78 A0A8I6A9A2 A0A8I6AT29 Q07141 Q9EQH5 Q9JIT3 Q9QXN1 Q9Z2F5	Bars Ctbp1 Ctbp2 Ctbp3 Esp2 Esp3 Grg4 Lef1 Tcf7 Tcf7l1 Tcf7l2 Tle1 Tle2 Tle3 Tle4	Rattus norvegicus (Norway rat)
LDL clearance	AP-2 complex subunit alpha-2 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Apolipoprotein B-100 Clathrin heavy chain 1 Clathrin light chain A Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor Lysosomal acid lipase/cholesteryl ester hydrolase NPC intracellular cholesterol transporter 1 NPC intracellular cholesterol transporter 2 Neutral cholesterol ester hydrolase 1 Proprotein convertase subtilisin/kexin type 9 Sterol O-acyltransferase 1 Sterol O-acyltransferase 2	A0A8I6A4J2 A0A8I6AWS0 B2GV54 D3ZAR1 G3V7K5 O70536 P08081 P11442 P18484 P35952 P59996 P62744 P62944 P84092 Q64194 Q7TMA5 Q7TQM4	Aadacl1 Acact Acat Acat2 Adtab Ap17 Ap2a1 Ap2a2 Ap2b1 Ap2m1 Ap2s1 Apob Arh Clapb1 Claps2 Clta Cltc Lal Ldlr Ldlrap1 Lip1 Lipa Narc1 Nceh1 Npc1 Npc2 Pcsk9 Soat1 Soat2	Rattus norvegicus (Norway rat)
RUNX1 regulates transcription of genes involved in BCR signaling	Core-binding factor subunit beta Paired box 5 Runt-related transcription factor 1	A0A8I5ZL27 A0A8I6GMB2 Q63046	Aml1 Cbfa2 Cbfb Pax5 Runx1	Rattus norvegicus (Norway rat)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) 3 beta-hydroxysteroid dehydrogenase type 7 Acyl-coenzyme A thioesterase 8 Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1 member D1 Aldo-keto reductase family 1, member C1 Alpha-methylacyl-CoA racemase Bile acid receptor Bile acid-CoA Bile salt export pump Cytochrome P450 7A1 Cytochrome P450 family 8 subfamily B member 1 Long-chain fatty acid transport protein 2 Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 2 Nuclear receptor coactivator Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal multifunctional enzyme type 2 Prostacyclin synthase Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial Sterol carrier protein 2	A0A8I6APA0 G3V8J2 O35048 O70127 P11915 P17178 P18125 P31210 P70473 P97524 P97562 P97852 Q05343 Q3MHS3 Q62735 Q62969 Q63276 Q63688 Q6AYQ2 Q8VHK0 Q9ES38 Q9WUI9	Abcb11 Acot8 Acox2 Acsb Acsvl1 Akr1c1 Akr1c21 Akr1d1 Amacr Baat Bar Bsep Cca2 Cyp27 Cyp27a1 Cyp7 Cyp7a1 Cyp7b1 Cyp8 Cyp8b1 Edh17b4 Facvl1 Fatp2 Fatp5 Fxr Hsd17b4 Hsd17b5 Hsd3b7 Ncoa1 Ncoa2 Nr1h4 Nr2b1 Pte1 Ptgis Rip14 Rxra Scp-2 Scp2 Slc27a2 Slc27a5 Spgp Thcox Tif2 Vlacs Vlacsr Vlcs	Rattus norvegicus (Norway rat)
PCP/CE pathway	Dishevelled associated activator of morphogenesis 1 Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 Frizzled class receptor 3 Frizzled class receptor 7 Frizzled-1 Frizzled-6 Profilin-1 Protein Wnt-4 Protein Wnt-5a Protein Wnt Protein Wnt Protein Wnt Rac family small GTPase 2 Ras-related C3 botulinum toxin substrate 1 Segment polarity protein dishevelled homolog DVL-1 Transforming protein RhoA	A0A8I6A1P8 A0A8I6GKX7 A0A8I6GM04 B1WBR9 D3ZB71 D4A9J2 D4ACM8 G3V6L1 G3V819 M0RCN5 P61589 P62963 Q08463 Q6RUV5 Q9QXQ5 Q9QXQ7 Q9WVB9	Arha Arha2 Daam1 Dvl1 Dvl2 Dvl3 Fzd1 Fzd3 Fzd6 Fzd7 LOC100361515 Pfn1 Rac Rac1 Rac2 Rhoa Wnt-4 Wnt-5a Wnt1 Wnt11 Wnt4 Wnt5a Wnt5b	Rattus norvegicus (Norway rat)
NCAM1 interactions	Alpha-2,8-sialyltransferase 8B Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IV alpha 5 chain Neural cell adhesion molecule 1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	A0A0G2K742 A0A8I5ZZ86 A1KQY6 F1LRJ1 F1M6Q3 F1MA59 P13596 Q07977	Col4a1 Col4a2 Col4a3 Col4a4 Col4a5 LOC100911572 Ncam Ncam1 Siat8b St8sia2 St8sia4 Stx	Rattus norvegicus (Norway rat)
Regulation of APC/C activators between G1/S and early anaphase	Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Cell division cycle 16 Cell division cycle 23 Cell division cycle protein 20 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 1 Cyclin-dependent kinase 2 E2 ubiquitin-conjugating enzyme Fizzy and cell division cycle 20 related 1 G2/mitotic-specific cyclin-B1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S	A0A0G2JVY9 A0A8I6A4J8 A0A8I6AE10 A0A8I6ANL9 A1L1K3 B1WCA1 B5DFI8 D3ZDK2 D3ZDN9 D3ZIT4 D3ZQX4 D3ZUB7 D3ZUW6 F1M3L4 F7EWF8 P30277 P39951 Q4V8A2 Q62623 Q63699 Q6AY13 Q6YDN7	Anapc1 Anapc15 Anapc16 Anapc2 Anapc4 Anapc5 Anapc7 Ccna1 Ccna2 Ccnb1 Cdc16 Cdc2 Cdc20 Cdc23 Cdc26 Cdc27 Cdc2a Cdk1 Cdk2 Cdkn1 Cdkn2 Fzr1 LOC100366017 Ube2c Ube2d1 Ube2e1 Ube2s	Rattus norvegicus (Norway rat)
Regulation of necroptotic cell death	Baculoviral IAP repeat-containing 2 Baculoviral IAP repeat-containing 3 Caspase-8 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase XIAP E3 ubiquitin-protein ligase parkin E3 ubiquitin-protein ligase FAS-associated death domain protein Flotillin-1 Flotillin-2 Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Mixed lineage kinase domain like pseudokinase Polyubiquitin-B Polyubiquitin-C Programmed cell death 6-interacting protein Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 Syntenin-1 TNF receptor-associated factor Tumor necrosis factor receptor type 1-associated DEATH domain protein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JTI9 A0A8I5ZV82 A0A8I5ZZU1 A0A8I6A5Y3 B5DFH7 D3Z8W5 D3ZYL0 D3ZZC5 P0CG51 P56558 P62982 P82995 Q63429 Q63692 Q6P6S1 Q8R2E7 Q9JHX4 Q9JI92 Q9JK66 Q9QZA2 Q9R0I6 Q9Z1E1 Q9Z2P5 Q9Z2S9	Aip1 Api3 Birc2 Birc3 Birc4 Casp8 Cdc37 Fadd Flot1 Flot2 Hsp86 Hsp90aa1 Hspca Itch LOC100360645 Mlkl NEWGENE_1308361 Ogt Park2 Pdcd6ip Prkn Reg1 Reg2 Rip3 Ripk1 Ripk3 Rps27a Sdcbp Tradd Traf2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube2l3 Xiap	Rattus norvegicus (Norway rat)
ARMS-mediated activation	Adapter molecule crk Beta-nerve growth factor High affinity nerve growth factor receptor Kinase D-interacting substrate of 220 kDa Ras-related protein Rap-1A	P25427 P35739 P62836 Q63768 Q9EQG6	Arms Crk Crko Kidins220 Krev1 Ngf Ngfb Ntrk1 Rap1a Trk Trka	Rattus norvegicus (Norway rat)
Formation of xylulose-5-phosphate	Aldo-keto reductase family 1 member A1 L-xylulose reductase Lambda-crystallin homolog Sorbitol dehydrogenase Xylulose kinase	P27867 P51635 Q3MIF4 Q811X6 Q920P0	Akr1a1 Alr Cry Cryl1 Dcxr Glb Sdh1 Sord Xylb	Rattus norvegicus (Norway rat)
Vitamin D (calciferol) metabolism	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial Cubilin Cytochrome P450, family 2, subfamily r, polypeptide 1 Legumain Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Protein inhibitor of activated STAT, 4 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 2 Vitamin D-binding protein Vitamin D3 receptor	A0A8I6A0G3 B5DFF9 D3ZAR1 O35132 O70244 P04276 P13053 P61959 P63281 P98158 Q09128 Q9R0J8	Arh Cubn Cyp24 Cyp24a1 Cyp27b Cyp27b1 Cyp2r1 Dbp Gc Ifcr Ldlrap1 Lgmn Lrp2 Nr1i1 Pias4 Prsc1 Smt3a Smt3h2 Sumo2 Ubce9 Ube2i Vdr	Rattus norvegicus (Norway rat)
Surfactant metabolism	Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Coiled-coil domain containing 59 Cytoskeleton-associated protein 4 LIM and cysteine-rich domains 1 Napsin A aspartic peptidase P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Transcription factor GATA-6 Transcription termination factor 1	A0A0G2K1Q8 A0A8I6AA77 D3ZH41 D4ADF2 F7FL28 P00786 P08427 P11685 P22086 P22355 P22909 P29276 P30543 P35248 P41232 P46153 Q06496 Q6AYF2 Q9JJ09 Q9JKR5 Q9WVT0	Abca3 Adgrf5 Adora2a Adora2b Adra2a Adra2c Ccdc59 Ckap4 Ctsh Gata6 Gpr116 Gprhep Lmcd1 Napsa P2ru1 P2ry2 Sftp-1 Sftp1 Sftp2 Sftp3 Sftp4 Sftpa Sftpa1 Sftpb Sftpc Sftpd Slc17a2 Slc34a1 Slc34a2 Srec Ttf1 Zdhhc2	Rattus norvegicus (Norway rat)
Regulation of cholesterol biosynthesis by SREBP (SREBF)	GTP-binding nuclear protein Ran Importin subunit beta-1 Membrane-bound transcription factor site-1 protease Sterol regulatory element-binding protein 1 Sterol regulatory element-binding protein 2 Sterol regulatory element-binding protein cleavage-activating protein	A2RRU4 P52296 P56720 P62828 Q3T1I5 Q9WTZ3	Kpnb1 Mbtps1 Ran S1p Scap Ski1 Srebf1 Srebf2 Srebp1	Rattus norvegicus (Norway rat)
Intrinsic Pathway of Fibrin Clot Formation	Ac2-248 Alpha-2-macroglobulin Coagulation factor IX Coagulation factor VIII Coagulation factor X Coagulation factor XI Coagulation factor XII Complement component 1 Q subcomponent-binding protein, mitochondrial Glia-derived nexin Glycoprotein 9 Glycoprotein Ib platelet subunit alpha Heparin cofactor 2 Kininogen-1 Plasma kallikrein Plasma protease C1 inhibitor Platelet glycoprotein Ib beta chain Platelet glycoprotein V Prolylcarboxypeptidase Prothrombin Serpin family A member 5 Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A0G2K4I9 D3ZEB1 D3ZQU7 D3ZTE0 D4AA31 F7EMJ6 O08770 O35796 P06238 P07092 P08934 P14272 P16296 P18292 P31394 P53813 Q4AEG0 Q63207 Q64268 Q6P734 Q7TPI9 Q9JJM7	A2m A2m1 C1qbp Cf9 F10 F11 F12 F2 F8 F9 Gc1qbp Gp1ba Gp1bb Gp5 Gp9 Hcf2 Klk3 Klkb1 Kng Kng1 Pi7 Pk Pn1 Prcp Proc Pros Pros1 Serpina5 Serpinc1 Serpind1 Serpine2 Serping1	Rattus norvegicus (Norway rat)
CD28 co-stimulation	CD86 molecule Cd80 molecule GRB2-related adaptor protein 2 Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene tyrosine-protein kinase Src T-cell-specific surface glycoprotein CD28 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	F1LM93 G3V671 O35531 P31042 Q01621 Q07014 Q3KR57 Q62844 Q9WUD9	Cd28 Cd80 Cd86 Fyn Grap2 Lck Lyn Src Yes1	Rattus norvegicus (Norway rat)
Interleukin-1 signaling	Beta-transducin repeat containing E3 ubiquitin protein ligase Cullin 1 E3 ubiquitin-protein ligase pellino homolog Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor accessory protein Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-1 receptor-associated kinase 3 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Polyubiquitin-B Polyubiquitin-C RELA proto-oncogene, NF-kB subunit Ring-box 1 S-phase kinase-associated protein 1 Sequestosome-1 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Toll-interacting protein Ubiquitin B-like Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eS31 fusion protein mitogen-activated protein kinase kinase non-specific serine/threonine protein kinase	A0A0G2JUC8 A0A0G2JYX9 A0A0U1RRU5 A0A8I5Y0H0 A0A8I5ZMV7 A0A8I6A3Q1 A0A8I6A5Y3 A0A8I6ABN5 A0A8I6AH74 A0A8I6ANR6 A0A8I6G1H3 A0A8I6G2R1 A2RUW1 B2RYC8 B5DF45 D3ZSK3 O08623 P0C8E4 P0CG51 P16598 P25086 P43303 P62982 Q02955 Q4QQS0 Q5U303 Q63264 Q63429 Q63621 Q63746 Q6PEC4 Q6TMG5 Q6Y1S1 Q925D6 Q9QY78	Btrc Chuk Cul1 ENSRNOG00000067007 Ikba Ikbkb Ikbkg Ikkb Il-1r2 Il-1ra Il1a Il1b Il1r1 Il1r2 Il1ra Il1rap Il1rb Il1rn Irak1 Irak2 Irak3 Irak4 LOC100360645 Map2k6 Map3k7 Map3k7ip2 Mkk6 Myd88 Nemo Nfkbia Peli2 Rbx1 Rela Rps27a Skp1 Skp1a Sqstm1 Tab1 Tab2 Tab3 Tollip Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Zip	Rattus norvegicus (Norway rat)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Interleukin-1 receptor-associated kinase-like 2 Lymphocyte antigen 96 Mitogen-activated protein kinase kinase kinase 7 Monocyte differentiation antigen CD14 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 6 Toll-like receptor 4 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 D3ZXR7 M0RA08 P0C8E4 P0CG51 P62982 Q4QQS0 Q56DL5 Q5U303 Q63429 Q63691 Q9QX05	Cd14 Irak2 LOC100360645 Ly96 Map3k7 Map3k7ip2 Plin3 Rps27a Tab1 Tab2 Tab3 Ticam1 Ticam2 Tlr4 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
RUNX3 regulates YAP1-mediated transcription	Runt-related transcription factor TEA domain transcription factor 1 TEA domain transcription factor 2 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-5	A0A0G2K2S9 A0A0G2K7T0 A0A8I5ZMT2 A0A8I6AIX9 A0A8I6GMF8 Q2EJA0	Runx3 Tead1 Tead2 Tead3 Tead4 Yap Yap1 Yap65	Rattus norvegicus (Norway rat)
Acetylcholine regulates insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit alpha Myristoylated alanine-rich C-kinase substrate Protein kinase C alpha type	A0A8J8XRQ3 O88302 O89040 P05696 P10687 P30009 P82471 Q99JE6 Q9JID2	Gna11 Gna14 Gna15 Gnaq Macs Marcks Pkca Plcb1 Plcb2 Plcb3 Prkca	Rattus norvegicus (Norway rat)
Transport of RCbl within the body	CD320 antigen Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Multidrug resistance-associated protein 1 Transcobalamin-2	D3ZAR1 P98158 Q5HZW5 Q8CG09 Q9R0D6	Abcc1 Arh Cd320 Ldlrap1 Lrp2 Mrp1 Tcn2	Rattus norvegicus (Norway rat)
Noncanonical activation of NOTCH3	Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 3 Nicastrin Presenilin-1 Presenilin-2 Y-box-binding protein 1	F7EYZ3 O88777 P62961 P97887 Q6QI68 Q8CGU6 Q9R172	Aph1a Ncstn Notch3 Ps2 Psen1 Psen2 Psenen Psnl1 Psnl2 Yb1 Ybx1	Rattus norvegicus (Norway rat)

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