GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **651 - 675** of **1070** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
IRAK2 mediated activation of TAK1 complex	Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TNF receptor-associated factor 6 Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0U1RRU5 A0A8I6A5Y3 A0A8I6ABN5 B5DF45 P0C8E4 P0CG51 P62982 Q4QQS0 Q5U303 Q63429	Irak2 LOC100360645 Map3k7 Map3k7ip2 Rps27a Tab1 Tab2 Tab3 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
IL-6-type cytokine receptor ligand interactions	Cardiotrophin-1 Cardiotrophin-like cytokine factor 1 Ciliary neurotrophic factor receptor subunit alpha Ciliary neurotrophic factor Cytokine receptor-like factor 1 Interleukin 31 receptor A Interleukin 31 Interleukin-11 receptor subunit alpha Interleukin-11 Interleukin-6 receptor subunit beta Leukemia inhibitory factor receptor Leukemia inhibitory factor Oncostatin-M-specific receptor subunit beta Oncostatin-M Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I5ZNP8 A0A8I6AM23 A0A8I6GGY9 D3ZD03 D3ZIV9 F1LZR4 O70535 P17777 P20294 P40190 Q08406 Q62689 Q63086 Q65Z14 Q65Z15 Q99MF4 Q99MF5	Clcf1 Cntf Cntfr Crlf1 Ctf1 Il11 Il11ra1 Il31 Il31ra Il6st Jak1 Jak2 Lif Lifr Osm Osmr Osmrb Tyk2	Rattus norvegicus (Norway rat)
IKK complex recruitment mediated by RIP1	Baculoviral IAP repeat-containing 2 Baculoviral IAP repeat-containing 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 NF-kappa-B essential modulator NF-kappa-B essential modulator Polyubiquitin-B Polyubiquitin-C Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain containing adaptor molecule 2 TIR domain-containing adapter molecule 1 Toll-like receptor 4 Ubiquitin B-like Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JTI9 A0A8I6A5Y3 A0A8I6AH74 A0A8I6ANR6 D3ZDK2 D3ZUM2 D3ZXR7 D3ZYL0 M0RA08 P0CG51 P61078 P62839 P62982 Q56DL5 Q63429 Q63691 Q6P6S1 Q6TMG5 Q9QX05 Q9QY78 Q9Z2P5	Birc2 Birc3 Cd14 Chuk Ikbkb Ikbkg Ikkb LOC100360645 Ly96 Nemo Plin3 Rip3 Ripk1 Ripk3 Rps27a Sarm1 Ticam1 Ticam2 Tlr4 Uba80 Ubb Ubbl1 Ubc Ubc4 Ubcep1 Ubch4 Ubch5b Ubcl1 Ube2d1 Ube2d2 Ube2d3	Rattus norvegicus (Norway rat)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A8I6AM23 D4A109 F7FHZ1 P01581 P11345 P21708 P63086 Q62689	Erk1 Erk2 Ifng Ifngr1 Ifngr2 Jak1 Jak2 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Raf Raf1	Rattus norvegicus (Norway rat)
Hydrolysis of LPC	Cytosolic phospholipase A2 Lysosomal phospholipase A and acyltransferase Phospholipase A2 group IVC Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1	D3Z9B7 D3ZQH6 D4A1I6 F1LMQ4 F1LPY6 P50393 Q5U2V4 Q675A5	Cpla2 Lypla3 Pla2g15 Pla2g4 Pla2g4a Pla2g4b Pla2g4c Pla2g4d Pla2g4e Pla2g4f Plbd1	Rattus norvegicus (Norway rat)
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta CD44 antigen Calcineurin B homologous protein 1 Hyaluronidase-1 Hyaluronidase-2 Hyaluronidase-3 Sodium/hydrogen exchanger 1	P06760 P26051 P26431 P61023 Q641X3 Q6AXR4 Q76HM9 Q76HN1 Q9Z2Q3	Cd44 Chp Chp1 Gus Gusb Hexa Hexb Hyal1 Hyal2 Hyal3 Nhe1 Slc9a1	Rattus norvegicus (Norway rat)	G35674CY
Hyaluronan biosynthesis and export	ATP-binding cassette sub-family C member 5 Cell migration inducing hyaluronidase 1 Hyaluronan synthase 2 hyaluronan synthase hyaluronan synthase	D3ZWI0 O35776 Q8CH92 Q8CH93 Q9QYM0	Abcc5 Cemip HAS1 HAS3 Has1 Has2 Has3 LOC282821 Mrp5 RGD1305254	Rattus norvegicus (Norway rat)	G35674CY
HuR (ELAVL1) binds and stabilizes mRNA	Acidic leucine-rich nuclear phosphoprotein 32 family member A ELAV-like protein 1 Exportin-1 Nucleoporin 214 Protein SET Protein kinase C alpha type Protein kinase C delta type TNF superfamily member 13	A0A8J8XC20 B5DF91 D4ACK1 P05696 P09215 P49911 Q63945 Q80U96	Anp32a Crm1 Elavl1 Hur Lanp Nup214 Pkca Pkcd Prkca Prkcd Set Tnfsf13 Xpo1	Rattus norvegicus (Norway rat)
Hormone ligand-binding receptors	Follicle-stimulating hormone receptor Follitropin subunit beta Glycoprotein hormone alpha-2 Glycoprotein hormone subunit beta 5 Glycoprotein hormones alpha chain Gonadotropin-releasing hormone receptor Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Progonadoliberin-1 Thyrotropin receptor Thyrotropin subunit beta	P01230 P04652 P07490 P11962 P16235 P18427 P20395 P21463 P30969 Q5VJF5 Q925Q4	Cga Cga1 Fshb Fshr Gnrh Gnrh1 Gnrhr Gpa2 Gpb5 Gpha2 Gphb5 Lhb Lhcgr Tshb Tshr Zsig51	Rattus norvegicus (Norway rat)
Histamine receptors	Histamine H1 receptor Histamine H2 receptor Histamine H2 receptor Histamine H3 receptor Histamine H4 receptor	F1LNK8 P25102 P31390 Q91ZY1 Q9QYN8	Hrh1 Hrh2 Hrh3 Hrh4	Rattus norvegicus (Norway rat)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Acetylcholine receptor subunit delta Acetylcholine receptor subunit epsilon Acetylcholine receptor subunit gamma Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-4	P04757 P09483 P09660 P12390 P12392 P18916 P25110	Achre Achrg Acra3 Acra4 Acrb2 Acrb4 Acrd Chrna3 Chrna4 Chrnb2 Chrnb4 Chrnd Chrne Chrng	Rattus norvegicus (Norway rat)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-6 Neuronal acetylcholine receptor subunit alpha-7 Neuronal acetylcholine receptor subunit alpha-9 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-3 Neuronal acetylcholine receptor subunit beta-4	P04757 P09483 P12389 P12390 P12391 P12392 P20420 P25108 P43143 P43144 Q05941	Acra Acra2 Acra3 Acra4 Acra5 Acra6 Acra7 Acra9 Acrb2 Acrb3 Acrb4 Chrna1 Chrna2 Chrna3 Chrna4 Chrna5 Chrna6 Chrna7 Chrna9 Chrnb2 Chrnb3 Chrnb4	Rattus norvegicus (Norway rat)
Highly calcium permeable nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-6 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-3 Neuronal acetylcholine receptor subunit beta-4	P04757 P09483 P12389 P12390 P12391 P12392 P20420 P25108 P43143	Acra Acra2 Acra3 Acra4 Acra5 Acra6 Acrb2 Acrb3 Acrb4 Chrna1 Chrna2 Chrna3 Chrna4 Chrna5 Chrna6 Chrnb2 Chrnb3 Chrnb4	Rattus norvegicus (Norway rat)
Heme signaling	Apolipoprotein A-I Apolipoprotein B-100 BTB domain and CNC homolog 1 C-type lectin domain family 1 member B Exportin-1 Hemoglobin subunit alpha-1/2 Hemoglobin subunit beta-1 Lymphocyte antigen 96 Membrane-associated progesterone receptor component 2 Proton-coupled folate transporter Toll-like receptor 4	D3ZJD8 D4ACD2 P01946 P02091 P04639 Q56DL5 Q5EBA8 Q5XIU9 Q7TMA5 Q80U96 Q9QX05	Apoa1 Apob Bach1 Clec1b Crm1 Hba-a1 Hba1 Hbb Hcp1 LOC100911490 Ly96 Pcft Pgrmc2 Slc46a1 Tlr4 Xpo1	Rattus norvegicus (Norway rat)
Heme degradation	ATP-binding cassette sub-family C member 2 Albumin Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Glutathione S-transferase A6 Glutathione S-transferase alpha-1 Glutathione S-transferase alpha-2 Glutathione S-transferase alpha-3 Glutathione S-transferase alpha-5 Heme oxygenase 1 Heme oxygenase 2 Multidrug resistance-associated protein 1 NAD(P)-binding domain-containing protein Solute carrier organic anion transporter family member 1B2 Solute carrier organic anion transporter family member 2B1 UDP-glucuronosyltransferase 1-2 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A5	A0A8I6A3K7 P00502 P02692 P02770 P04903 P04904 P06762 P20720 P23711 P46418 P46844 Q63120 Q64550 Q64637 Q64638 Q6AXY0 Q80W57 Q8CG09 Q9JHI3 Q9QZX8	Abcc1 Abcc2 Abcg2 Alb Bcrp1 Blvr Blvra Cmoat Cmrp ENSRNOG00000064875 Fabp1 Gsta1 Gsta2 Gsta3 Gsta5 Gsta6 Gstyc1 Gstyc2 Hmox1 Hmox2 Mrp1 Mrp2 Oatp1b2 Oatp2b1 Slc21a10 Slc21a9 Slco1b2 Slco2b1 Ugt1 Ugt1a1 Ugt1a2 Ugt1a3 Ugt1a5	Rattus norvegicus (Norway rat)
Heme biosynthesis	5-aminolevulinate synthase, erythroid-specific, mitochondrial 5-aminolevulinate synthase, non-specific, mitochondrial 5-aminolevulinate synthase Albumin Amine oxidase Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome c oxidase assembly homolog COX15 Delta-aminolevulinic acid dehydratase Ferrochelatase Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial Porphobilinogen deaminase Protoheme IX farnesyltransferase, mitochondrial Uroporphyrinogen decarboxylase (Fragment) uroporphyrinogen-III synthase	A0A8I6GEM4 D3ZVN7 D4A414 F1LVF4 F1LVW9 P02770 P06214 P13195 P19356 P32362 Q3B7D0 Q5XIF2 Q63147 Q80W57	Abcg2 Alad Alas1 Alas2 Alase Alb Bcrp1 Cox10 Cox15 Cpo Cpox Fech Hmbs LOC100911779 Ppox Urod Uros	Rattus norvegicus (Norway rat)
Hedgehog ligand biogenesis	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Derlin Endoplasmic reticulum lectin Hedgehog acyltransferase Hedgehog protein Hedgehog protein Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein OS-9 Protein disulfide-isomerase Protein sel-1 homolog 1 RING-type E3 ubiquitin transferase Sonic hedgehog protein Transitional endoplasmic reticulum ATPase Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2KAX0 A0A8I5ZM79 A0A8I5ZNE7 A0A8I6A5Y3 A0A8I6AMH0 A0A8I6GIY5 B0BN93 D3ZF97 F1LMQ3 F1LMZ8 F1LP42 F1M6I7 F7FG68 F7FGV7 G3V6W6 G3V7Y0 G3V8G2 O88761 P04785 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P46462 P48004 P60901 P62193 P62198 P62982 Q4FZT9 Q4KM35 Q4V8E2 Q5RKH6 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63673 Q63797 Q63798 Q80Z70 Q9JHW0 Q9WTV5 Q9Z2X3	Derl2 Dhh Erlec1 Hhat Ihh LOC100360645 LOC100360846 LOC100365869 LOC100910831 Lmp10 Lmp2 Mecl1 Mss1 Os9 P4hb Pdia1 Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ring12 Rps27a Sel1h Sel1l Shh Sug1 Syvn1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Vcp Vhh-1	Rattus norvegicus (Norway rat)
Hedgehog 'on' state	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-3 DAZ interacting zinc finger protein 1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase EvC ciliary complex subunit 1 EvC ciliary complex subunit 2 G protein-coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Kinesin family member 7 Parafibromin Patched Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Protein numb homolog Protein smoothened Ring-box 1 Serine/threonine-protein kinase ULK3 Speckle type BTB/POZ protein like Speckle type BTB/POZ protein Suppressor of fused homolog Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2JSL0 A0A0G2JUC8 A0A0G2K3W8 A0A0G2K612 A0A0G2KAX0 A0A0G2KB38 A0A8I5Y0P5 A0A8I5ZM79 A0A8I5ZNE7 A0A8I5ZVC1 A0A8I5ZZU1 A0A8I6A5Y3 A0A8I6A606 B0BN93 B5DF89 D3ZHP7 D3ZWN3 D4A9P0 F1LMQ3 F1LMZ8 F1M2B7 F1M5Q2 F1M6I7 F1M9H1 F7FGV7 G3V6W6 G3V6X8 G3V706 G3V8G2 O88761 P0CG51 P17220 P18420 P18421 P18422 P21670 P28064 P28073 P28075 P28077 P34064 P34067 P40112 P40307 P48004 P60901 P62193 P62198 P62982 P97698 Q2LC84 Q4FZT9 Q4KM35 Q4V8C8 Q4V8E2 Q5XIC6 Q5XIU5 Q63347 Q63429 Q63569 Q63570 Q63797 Q63798 Q6UY90 Q9JHW0 Q9WTV5 Q9Z2X3	Cdc73 Cul3 Dzip1 Evc Evc2 Gli1 Gli2 Gli3 Gpr161 Hrpt2 Itch Kif7 LOC100360645 LOC100360846 LOC100365869 Lmp10 Lmp2 Mecl1 Mss1 Numb Psma1 Psma2 Psma3 Psma4 Psma5 Psma6 Psma7 Psma8 Psmb1 Psmb10 Psmb2 Psmb3 Psmb4 Psmb5 Psmb6 Psmb6l Psmb6l1 Psmb7 Psmb8 Psmb9 Psmc1 Psmc2 Psmc3 Psmc4 Psmc5 Psmc6 Psmd1 Psmd10 Psmd11 Psmd12 Psmd13 Psmd14 Psmd2 Psmd3 Psmd5 Psmd6 Psmd7 Psmd8 Psmd9 Psme1 Psme2 Psme4 Psmf1 Ptch Ptch1 Rbx1 Ring12 Rps27a Smo Smoh Smurf1 Smurf2 Spop Spopl Sufu Sug1 Tbp1 Tbp7 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ulk3	Rattus norvegicus (Norway rat)
Hedgehog 'off' state	Adenylate cyclase type 10 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Cytoplasmic dynein 2 heavy chain 1 G protein-coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Intraflagellar transport 140 Intraflagellar transport 52 Intraflagellar transport 88 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 57 homolog Kinesin family member 7 Kinesin-like protein Ofd1 centriole and centriolar satellite protein Patched Protein fuzzy homolog Protein inturned Protein smoothened Rpgrip1-like Suppressor of fused homolog Tectonic-like complex member MKS1 Tetratricopeptide repeat domain 21B Tubby-like protein WD repeat domain 19 WD repeat-containing protein 35 adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A0A0G2JZL6 A0A8I5Y075 A0A8I5ZPQ6 A0A8I6A606 A0A8I6AA62 A0A8I6GBB8 A6N6J5 D3Z8G3 D4A1V1 D4A3N4 D4A9P0 D4ACE5 F1LQT1 F1LQZ3 F1LV01 F1LY69 F1M2B7 F1M5Q2 F1M656 F1M9H1 G3V6X8 M0R5U4 P09456 P12368 P12369 P21932 P26769 P26770 P27791 P40146 P68182 P81377 P97698 Q03343 Q04400 Q3B756 Q499Q5 Q6UY90 Q9JJ79 Q9JKU3 Q9Z286	Adcy1 Adcy10 Adcy2 Adcy3 Adcy4 Adcy5 Adcy6 Adcy7 Adcy8 Adcy9 Dhc1b Dlp4 Dnch2 Dnchc2 Dync2h1 Fuz Gli1 Gli2 Gli3 Gpr161 Ift122 Ift140 Ift172 Ift52 Ift57 Ift88 Intu Kif3a Kif7 LOC100364088 Mks1 Ofd1 Pdzd6 Pkacb Prkaca Prkacb Prkar1a Prkar1b Prkar2a Prkar2b Ptch Ptch1 Rpgrip1l Sac Slb Smo Smoh Sufu Ttc21b Tulp3 Wdr19 Wdr35	Rattus norvegicus (Norway rat)
HSP90 chaperone cycle for SHRs	Actin related protein 10 Alpha-centractin Androgen receptor Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 DnaJ (Hsp40) homolog, subfamily A, member 4 DnaJ heat shock protein family (Hsp40) member B1 DnaJ homolog subfamily A member 1 DnaJ homolog subfamily A member 2 Dynactin 3-like 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha-3 F-actin-capping protein subunit beta Glucocorticoid receptor Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock-related 70 kDa protein 2 Mineralocorticoid receptor Peptidyl-prolyl cis-trans isomerase FKBP4 Progesterone receptor Prostaglandin E synthase 3 Stress-induced-phosphoprotein 1 peptidylprolyl isomerase	A0A8I5Y4I3 A0A8I6AIV4 A0A8I6B4B1 A0A8I6GBD2 B2GUZ5 D3ZUU5 F7EYK0 O35814 O35824 P06536 P0DMW0 P0DMW1 P14659 P15207 P22199 P28023 P34058 P38650 P55063 P63018 P63036 P63170 P82995 P83868 P85515 Q3T1K5 Q4QR73 Q5XI32 Q62698 Q62871 Q63100 Q63449 Q6AYH5 Q78P75 Q9QUR2 Q9QVC8 Q9QXU8 Q9WUV6	AABR07000222.1 Actr10 Actr1a Ar Capza1 Capza2 Capza3 Capzb Ctrn1 Dctn1 Dctn2 Dctn3l1 Dctn4 Dctn5 Dctn6 Dhc1 Dlc2 Dnaja1 Dnaja2 Dnaja4 Dnajb1 Dnch1 Dnchc1 Dnci1 Dnci2 Dncic1 Dncic2 Dncl1 Dnclc1 Dncli1 Dncli2 Dnec1 Dyhc Dync1h1 Dync1i1 Dync1i2 Dync1li1 Dync1li2 Dynll1 Dynll2 Fkbp4 Fkbp5 Fkbp52 Grl Hop Hsc70 Hsc73 Hsj2 Hsp70-1 Hsp70-2 Hsp70-3 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hspc3 Hspca Hspcb Hst70 Map1c Mlr Nr3c1 Nr3c2 Nr3c3 Nr3c4 Pgr Pin Ptges3 Rdj1 Stip1 Tebp	Rattus norvegicus (Norway rat)
HSF1-dependent transactivation	AKT1 substrate 1 Alpha-crystallin B chain Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma DnaJ heat shock protein family (Hsp40) member B1 Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock protein beta-8 Heat shock transcription factor 1 Regulatory associated protein of MTOR, complex 1 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8	A0A8I5ZRQ9 D3ZDU2 D3ZUU5 F1MAF1 P08413 P0DMW0 P0DMW1 P11275 P11730 P15791 P23928 P34058 P42346 P55063 P63018 P82995 Q8K3X8 Q9EPX0 Q9Z2K5	Akt1s1 Camk2a Camk2b Camk2d Camk2g Cryab Cryac Dnajb1 Frap1 Gbl Hsbp1 Hsc70 Hsc73 Hsf1 Hsp22 Hsp70-1 Hsp70-2 Hsp70-3 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspa1 Hspa1a Hspa1b Hspa1l Hspa2 Hspa8 Hspb8 Hspc3 Hspca Hspcb Lst8 Mlst8 Mtor Raft1 Rptor	Rattus norvegicus (Norway rat)
HSF1 activation	14-3-3 protein epsilon Elongation factor 1-alpha 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock transcription factor 1 Prostaglandin E synthase 3 Transitional endoplasmic reticulum ATPase	F1MAF1 P34058 P46462 P62260 P62630 P82995 P83868	Eef1a Eef1a1 Hsf1 Hsp84 Hsp86 Hsp90aa1 Hsp90ab1 Hspc3 Hspca Hspcb Ptges3 Tebp Vcp Ywhae	Rattus norvegicus (Norway rat)
HS-GAG degradation	Agrin Alpha-L-iduronidase Beta-galactosidase-1-like protein 3 Beta-galactosidase Beta-galactosidase Beta-glucuronidase Galactosidase, beta 1-like Glypican 4 Glypican 5 Glypican 6 Glypican-1 Glypican-2 Glypican-3 Heparanase 2 (inactive) Heparanase Iduronate 2-sulfatase N-acetyl-alpha-glucosaminidase N-sulfoglucosamine sulfohydrolase Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4	A0A8I5Y144 A0A8I5ZZ84 A0A8I6A609 A0A8I6ACQ6 A0A8I6AN52 B1WBS6 D3ZE16 D3ZUM4 D3ZZL3 F1LLW8 P06760 P13265 P25304 P26260 P33671 P34900 P34901 P35053 P51653 Q5XIL5 Q642B0 Q71RP1	Agrin Agrn Glb1 Glb1l Glb1l2 Glb1l3 Gpc1 Gpc2 Gpc3 Gpc4 Gpc5 Gpc6 Gus Gusb Hep Hpse Hpse2 Hspg1 Ids Idua LOC100363795 Naglu Sdc1 Sdc2 Sdc3 Sdc4 Sgsh Synd1 Synd2 Synd3 Synd4	Rattus norvegicus (Norway rat)	G01550VL G09546QO
HS-GAG biosynthesis	Agrin Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Exostosin glycosyltransferase 1 Exostosin glycosyltransferase 2 Glypican 4 Glypican 5 Glypican 6 Glypican-1 Glypican-2 Glypican-3 Heparan sulfate 2-O-sulfotransferase 1 Heparan sulfate glucosamine 3-O-sulfotransferase 1 Heparan sulfate glucosamine 3-O-sulfotransferase 2 Heparan-sulfate 6-O-sulfotransferase Heparan-sulfate 6-O-sulfotransferase Heparan-sulfate 6-O-sulfotransferase Solute carrier family 35 member D2 Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 [heparan sulfate]-glucosamine N-sulfotransferase [heparan sulfate]-glucosamine N-sulfotransferase [heparan sulfate]-glucosamine N-sulfotransferase	A0A0G2KAH7 A0A8I5ZN51 A0A8I5ZUU3 A0A8I6A609 A0A8I6ACQ6 D3ZD27 D3ZD62 D3ZDL1 D3ZEK5 D3ZFR1 D3ZGJ6 D3ZTA9 D4A1T9 D4A6E6 D4ABE3 G3V7N0 G3V901 P13265 P25304 P26260 P33671 P34900 P34901 P35053 P51653 Q02353 Q642B0 Q80W66 Q9ESG5	3ost 3ost1 3ost2 Agrin Agrn Ext1 Ext2 Gpc1 Gpc2 Gpc3 Gpc4 Gpc5 Gpc6 Hs2st1 Hs3st1 Hs3st2 Hs3st3a1 Hs3st3b1 Hs3st4 Hs3st5 Hs3st6 Hs6st1 Hs6st2 Hs6st3 Hspg1 Hsst Hsst1 Ndst1 Ndst2 Ndst3 Ndst4 Sdc1 Sdc2 Sdc3 Sdc4 Slc35d2 Synd1 Synd2 Synd3 Synd4	Rattus norvegicus (Norway rat)
HDMs demethylate histones	AT-rich interactive domain-containing protein 5B Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Histone H3.1 Histone H3 Histone H4 Lysine demethylase 1B Lysine demethylase 2A Lysine demethylase 7A Lysine-specific demethylase 3A Lysine-specific demethylase 4D Lysine-specific demethylase Lysine-specific histone demethylase PHD finger protein 2 PHD finger protein 8 Ribosomal oxygenase 2 [histone H3]-dimethyl-L-lysine(36) demethylase [histone H3]-trimethyl-L-lysine(27) demethylase [histone H3]-trimethyl-L-lysine(27) demethylase [histone H3]-trimethyl-L-lysine(27) demethylase [histone H3]-trimethyl-L-lysine(4) demethylase [histone H3]-trimethyl-L-lysine(4) demethylase [histone H3]-trimethyl-L-lysine(4) demethylase [histone H3]-trimethyl-L-lysine(4) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase	A0A0G2K1H0 A0A0G2K1Z1 A0A0G2K3N6 A0A0G2K5I7 A0A0G2K6V2 A0A0G2K736 A0A8I5ZPK6 A0A8I5ZVJ1 A0A8I5ZXX2 A0A8I6A5T3 A0A8I6ABR9 A0A8I6AEL5 A0A8I6AFH2 A0A8I6GMK8 A1A5Q5 D3ZJ08 D3ZP89 D3ZTJ7 D4AD31 F1LS62 M0RB75 P62804 Q63679 Q6AYK2 Q6LED0 Q8CFC1	Arid5b H3c13 H4c16 H4c2 H4f16 H4ft Hist1h4b Hist1h4m Hist2h3c2 Hist4 Hist4h4 Jhdm2a Jhdm3d Jmjd1a Jmjd2d Jmjd6 Kdm1a Kdm1b Kdm2a Kdm2b Kdm3a Kdm3b Kdm4a Kdm4b Kdm4c Kdm4d Kdm5a Kdm5b Kdm5c Kdm5d Kdm6a Kdm6b Kdm7a Mina Mina53 Phf2 Phf8 Ptdsr Riox2 Tsga Uty	Rattus norvegicus (Norway rat)

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