GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **701 - 725** of **1070** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Ovarian tumor domain proteases	Adenomatous polyposis coli protein Cellular tumor antigen p53 Cyclin-dependent kinase 1 Deubiquitinating protein VCPIP1 Estrogen receptor NF-kappa-B essential modulator NF-kappa-B essential modulator Nucleotide-binding oligomerization domain containing 1 Nucleotide-binding oligomerization domain containing 2 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Receptor interacting serine/threonine kinase 1 Receptor-interacting serine/threonine-protein kinase 2 Ring finger protein 128 TNF receptor-associated factor 6 TNF receptor-associated factor TNFAIP3 interacting protein 1 TNFAIP3 interacting protein 2 Transforming protein RhoA Transitional endoplasmic reticulum ATPase Ubiquitin B-like Ubiquitin thioesterase OTU1 Ubiquitin thioesterase OTUB1 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A0G2K4Z7 A0A0G2K5N0 A0A0G2K7X2 A0A8I6A5Y3 A0A8I6AH74 A0A8I6AL23 A0A8I6AU71 B2RYG6 B2RZ84 B5DF45 D3ZAR8 D3ZDK2 D3ZHV1 D3ZYL0 D4A3I0 D4A7M3 D4ABZ4 D4ADT7 G3V783 G3V7R6 P06211 P0CG51 P10361 P39951 P46462 P61589 P62982 P70478 Q32Q05 Q63429 Q6TMG5 Q8CF97	Apc Arha Arha2 Cdc2 Cdc2a Cdk1 Cdkn1 Esr Esr1 Estr Hshin7 Ikbkg LOC100360606 LOC100360645 Nemo Nod1 Nod2 Nr3a1 Otub1 Otub2 Otud3 Otud7a Otud7b P53 Pten Rhoa Ripk1 Ripk2 Rnf128 Rps27a Tnfaip3 Tnip1 Tnip2 Tp53 Traf3 Traf6 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ube2d1 Vcip135 Vcp Vcpip1 Yod1 Zranb1	Rattus norvegicus (Norway rat)
Apoptotic cleavage of cellular proteins	Adenomatous polyposis coli protein Apoptotic chromatin condensation inducer 1 B-cell receptor-associated protein Baculoviral IAP repeat-containing 2 Caspase 7 Caspase-3 Caspase-6 Caspase-8 Claspin DNA-binding protein SATB Focal adhesion kinase 1 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C delta type Protein kinase C theta type Rho-associated protein kinase 1 Serine/threonine-protein kinase 24 Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A0G2JXK2 A0A0G2JYZ8 A0A8I5ZQU7 A0A8I6GBQ0 B0LT89 D3ZHC3 E9PST5 F1LVI0 O35346 O35397 P09215 P55213 P70478 Q04631 Q63644 Q6P6S1 Q9JHX4 Q9WTQ0	Acin1 Apc Bcap31 Birc2 Bmx Casp3 Casp6 Casp7 Casp8 Clspn Cpp32 Fak Fak1 Fnta Mch2 Mst3 Pkcd Pkcq Prkcd Prkcq Ptk2 Rock1 Satb1 Stk24 Stk26 Stk3	Rattus norvegicus (Norway rat)
Cleavage of the damaged purine	Adenine DNA glycosylase Adrenocortical dysplasia protein homolog DNA-(apurinic or apyrimidinic site) lyase DNA-3-methyladenine glycosylase (Fragment) Histone H2A type 2-A Histone H2A.J Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1-A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor	A0A0G2JX31 A0A0G2JXI9 A0A8I5ZSA8 A0A8I5ZYY0 A0A8I6A2W1 A0A8I6A7P3 A0A8I6AFW8 A0A8I6AWT3 A0A8I6G659 A9UMV8 D3ZJF7 D3ZKJ8 D3ZVK7 D3ZXP3 D4ACM0 G3V9C7 M0RBQ5 O70249 P0CC09 P23571 P62804 Q00729 Q4FZR5 Q5EAN7 Q8R5G2	Acd ENSRNOG00000062927 ENSRNOG00000064540 ENSRNOG00000066901 ENSRNOG00000068034 H2ab3 H2ac10 H2ac18 H2ac4 H2afb3 H2afx H2aj H2ax H2az2 H2bc1 H2bc12l1 H2bc6 H2bcl1 H2bcl2 H2bu1 H4c16 H4c2 H4f16 H4ft Hist1h2ba Hist1h2bc Hist1h2bg Hist1h2bo Hist1h2bq Hist1h4b Hist1h4m Hist2h2aa3 Hist4 Hist4h4 LOC100365043 LOC100910200 LOC120097726 LOC684797 Mmh Mpg Mutyh Myh Neil3 Ogg1 Ogh1 Pot1 Rap1 Terf2 Terf2ip Th2b	Rattus norvegicus (Norway rat)
Ligand-independent caspase activation via DCC	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Caspase-3 Caspase-9 Netrin receptor DCC	D3ZWA8 P55213 Q63155 Q9JHK1	Appl1 Casp3 Casp9 Cpp32 Dcc RNCASP9	Rattus norvegicus (Norway rat)
Regulation of signaling by CBL	Adapter molecule crk Crk-like protein E3 ubiquitin-protein ligase CBL Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Proto-oncogene vav Rap guanine nucleotide exchange factor 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5Y949 A0A8I6G3R2 F1LM93 F1M8L9 P50545 P54100 P62994 Q07014 Q5U2U2 Q62844 Q63768 Q63787 Q63788 Q63789 Q64725 Q9Z1L0	Ash Cbl Crk Crkl Crko Fyn Grb2 Hck Lyn Pik3ca Pik3cb Pik3cd Pik3r1 Pik3r2 Pik3r3 Rapgef1 Syk Vav Vav1 Yes1	Rattus norvegicus (Norway rat)
MET activates RAP1 and RAC1	Adapter molecule crk Crk-like protein Dedicator of cytokinesis 7 GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rap-1A Ras-related protein Rap-1b	A0A0G2K3H2 D3ZAL7 F1M8L9 P17945 P62836 P62994 P97523 Q5U2U2 Q62636 Q63768 Q6RUV5	Ash Crk Crkl Crko Dock7 Gab1 Grb2 Hgf Krev1 Met Rac Rac1 Rap1a Rap1b Rapgef1	Rattus norvegicus (Norway rat)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Engulfment and cell motility 1 Engulfment and cell motility 2 GTPase HRas GTPase KRas GTPase NRas Paxillin Ras GTPase-activating protein 1 Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Transforming protein RhoA Tyrosine-protein kinase	D3ZDS3 D3ZY46 G3V982 P08644 P20171 P50904 P61589 P81128 Q04970 Q63767 Q63768 Q66H76 Q6RUV5	Arha Arha2 Arhgap35 Bcar1 Cas Crk Crkas Crko Elmo1 Elmo2 Grlf1 Hras Hras1 Kras Kras2 Nras P190A Ptk6 Pxn Rac Rac1 Rasa Rasa1 Rhoa p190ARHOGAP	Rattus norvegicus (Norway rat)
ARMS-mediated activation	Adapter molecule crk Beta-nerve growth factor High affinity nerve growth factor receptor Kinase D-interacting substrate of 220 kDa Ras-related protein Rap-1A	P25427 P35739 P62836 Q63768 Q9EQG6	Arms Crk Crko Kidins220 Krev1 Ngf Ngfb Ntrk1 Rap1a Trk Trka	Rattus norvegicus (Norway rat)
p130Cas linkage to MAPK signaling for integrins	Adapter molecule crk Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Breast cancer anti-estrogen resistance protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Focal adhesion kinase 1 Integrin beta-3 Integrin subunit alpha 2b Proto-oncogene tyrosine-protein kinase Src Ras-related protein Rap-1A Ras-related protein Rap-1b Talin 1	A0A8I6ABG6 A0A8I6GGN2 D3ZDZ1 O35346 P02680 P04937 P06399 P14480 P62836 Q62636 Q63767 Q63768 Q8R2H2 Q9WUD9	Apbb1ip Bcar1 Cas Crk Crkas Crko Fak Fak1 Fga Fgb Fgg Fn1 Itga2b Itgb3 Krev1 Ptk2 Rap1a Rap1b Src Tln1	Rattus norvegicus (Norway rat)
The retinoid cycle in cones (daylight vision)	Acyltransferase Medium-wave-sensitive opsin 1 Retinaldehyde binding protein 1 Retinol binding protein 3 Short-wave-sensitive opsin 1	D3Z956 D4A598 G3V8Q4 O35476 Q63652	Awat2 Bcp Gcp Opn1mw Opn1sw Rbp3 Rlbp1	Rattus norvegicus (Norway rat)
Arachidonic acid metabolism	Acyltransferase Cytosolic phospholipase A2 Fatty-acid amide hydrolase 1	D3ZVA9 P50393 P97612	Awat1 Cpla2 Faah Faah1 Pla2g4 Pla2g4a	Rattus norvegicus (Norway rat)
Acyl chain remodeling of DAG and TAG	Acyltransferase Acyltransferase Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2 Monoglyceride lipase Patatin-like phospholipase domain containing 3 Patatin-like phospholipase domain-containing protein 2	D3Z9J9 D3ZTG7 D4A598 P0C548 Q5FVP8 Q8R431 Q9ERM3	Atgl Awat2 Dgat Dgat1 Dgat2 Dgat2l6 Mgl2 Mgll Pnpla2 Pnpla3	Rattus norvegicus (Norway rat)
Glycerophospholipid biosynthesis	Acylglycerol kinase, mitochondrial Copine 3 Copine 6 Copine-1 Copine-7	D3Z9L0 D3ZLA3 D4A1R8 D4ACG7 H1UBN0	Agk Cpne1 Cpne3 Cpne6 Cpne7	Rattus norvegicus (Norway rat)
L1CAM interactions	Acyl-protein thioesterase 2 Neural cell adhesion molecule L1 Neuromodulin Ran-binding protein 9	A0A8I5Y176 P07936 Q05695 Q9QYL8	Caml1 Gap43 L1cam Lypla2 Ranbp9	Rattus norvegicus (Norway rat)
eNOS activation	Acyl-protein thioesterase 1 Calmodulin-3 Caveolin-1 Cytoglobin Heat shock protein HSP 90-alpha N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 Nitric oxide synthase 3 RAC-alpha serine/threonine-protein kinase Sepiapterin reductase	O08557 P0DP31 P18297 P41350 P47196 P70470 P82995 Q62600 Q921A4	Akt1 Apt1 CaMIII Calm3 Cam3 Camc Cav Cav1 Cygb Ddah Ddah1 Hsp86 Hsp90aa1 Hspca Lypla1 Nos3 Spr Stap	Rattus norvegicus (Norway rat)
Negative regulation of the PI3K/AKT network	Acyl-coenzyme A thioesterase THEM4 PH domain leucine-rich repeat protein phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Tribbles homolog 3	A0A8I6AU71 P47196 P47197 Q566R0 Q63484 Q9WTQ6 Q9WTR8	Akt1 Akt2 Akt3 Nipk Phlpp Phlpp1 Plekhe1 Pten Scop Them4 Trib3	Rattus norvegicus (Norway rat)
Beta-oxidation of pristanoyl-CoA	Acyl-coenzyme A oxidase Acyl-coenzyme A thioesterase 8 Alpha-methylacyl-CoA racemase Carnitine O-acetyltransferase Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal carnitine O-octanoyltransferase Peroxisomal multifunctional enzyme type 2 Sterol carrier protein 2	A0A8I5ZRR5 P11466 P11915 P70473 P97562 P97852 Q63448 Q704S8 Q8VHK0	Acot8 Acox2 Acox3 Acoxl Amacr Cot Crat Crot Edh17b4 Hsd17b4 Prcox Pte1 Scp-2 Scp2 Thcox	Rattus norvegicus (Norway rat)
Respiratory electron transport	Acyl carrier protein Coenzyme Q-binding protein COQ10 homolog B, mitochondrial Coenzyme Q10A Complex III subunit 9 Cytochrome b-c1 complex subunit 1, mitochondrial Cytochrome b-c1 complex subunit 2, mitochondrial Cytochrome b-c1 complex subunit 6, mitochondrial Cytochrome b-c1 complex subunit 7 Cytochrome b-c1 complex subunit 8 Cytochrome b-c1 complex subunit Rieske, mitochondrial Cytochrome b Cytochrome c domain-containing protein Cytochrome c oxidase assembly factor COX18 Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase copper chaperone COX11 Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6C-2 Cytochrome c oxidase subunit 7A2 like Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8A, mitochondrial Cytochrome c oxidase subunit Cytochrome c, somatic Cytochrome c-1 Electron transfer flavoprotein subunit alpha, mitochondrial Electron transfer flavoprotein subunit beta Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial Leucine-rich PPR motif-containing protein, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 Similar to Cytochrome c, somatic Surfeit locus protein 1 Synthesis of cytochrome C oxidase 1 Thymidine phosphorylase Translational activator of cytochrome c oxidase 1 Transmembrane protein 186	A0A0G2JYY6 A0A8I5Y9A4 A0A8I5ZKJ3 A0A8I5ZSY5 A0A8I5ZWG1 A0A8I5ZWM3 A0A8I6A5D4 A0A8I6A8X0 A0A8I6AAY1 A0A8I6AKU6 A0A8I6AL00 A0A8I6B100 B2RYS2 B2RYT9 B2RYX1 D3Z8B0 D3ZE15 D3ZF13 D3ZFQ8 D3ZG43 D3ZLT1 D3ZNJ0 D3ZQH7 D3ZXV2 D3ZZ21 D4A0T0 D4A3V2 D4A565 D4A568 D4A5L9 D4A7L4 F1LXA0 F1LZC5 F7ELE5 F7EXQ7 F7F9K9 G3V985 M0RB63 P00159 P00406 P03889 P03926 P05503 P05505 P05506 P05508 P10818 P10888 P11240 P11661 P11662 P11951 P12075 P13803 P19234 P20788 P32551 P52504 P62898 P80431 P80432 P80433 Q4KLZ1 Q561S0 Q5BK63 Q5I0I9 Q5M9I5 Q5SGE0 Q5XFV8 Q5XIF3 Q5XIH3 Q63362 Q641Y2 Q66HF1 Q68FU3 Q68FY0 Q6PCU8 Q6UPE1 Q7TQ16 Q80W89 Q9QXU2	AABR07056686.1 AC128290.1 COX2 Ccdc44 Cob Coi Coii Coiii Coq10a Coq10b Cox11 Cox14 Cox16 Cox18 Cox4 Cox4a Cox4i1 Cox5a Cox5b Cox6a1 Cox6al Cox6b1 Cox6c Cox6c2 Cox7a2l Cox7b Cox7c Cox7c1 Cox8 Cox8a Cox8l Cyc1 Cycs Cycsl2 Cycsl3 Cytb Etfa Etfb Etfdh Ip13 LOC100363268 LOC100911483 LOC103691107 LOC120096563 LOC120101567 LOC684509 LOC690675 Lrp157 Lrpprc Mt-co1 Mt-co2 Mt-co3 Mt-cyb Mt-nd1 Mt-nd2 Mt-nd3 Mt-nd4 Mt-nd5 Mt-nd6 Mtco1 Mtco2 Mtco3 Mtcyb Mtnd1 Mtnd4 Mtnd5 Mtnd6 Nd1 Nd2 Nd3 Nd4 Nd5 Nd6 Ndufa10 Ndufa11 Ndufa12 Ndufa13 Ndufa2 Ndufa3-ps3 Ndufa5 Ndufa6 Ndufa8 Ndufa9 Ndufab1 Ndufb10 Ndufb11 Ndufb2 Ndufb3 Ndufb4l5 Ndufb5 Ndufb6 Ndufb7 Ndufb8 Ndufc1 Ndufs1 Ndufs2 Ndufs3 Ndufs4 Ndufs5 Ndufs5-ps2 Ndufs6 Ndufs7 Ndufs8 Ndufv1 Ndufv2 Ndufv3 Qpc RGD1562558 Sco1 Surf-1 Surf1 Taco1 Tmem186 Tymp Uqcr10 Uqcrb Uqcrc1 Uqcrc2 Uqcrfs1 Uqcrh Uqcrq	Rattus norvegicus (Norway rat)
Complex I biogenesis	Acyl carrier protein Arginine-hydroxylase NDUFAF5, mitochondrial Complex I assembly factor ACAD9, mitochondrial Complex I assembly factor TIMMDC1, mitochondrial Complex I assembly factor TMEM126B, mitochondrial Complex I intermediate-associated protein 30, mitochondrial Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NADH-ubiquinone oxidoreductase chain 1 NADH-ubiquinone oxidoreductase chain 2 NADH-ubiquinone oxidoreductase chain 3 NADH-ubiquinone oxidoreductase chain 4 NADH-ubiquinone oxidoreductase chain 5 NADH-ubiquinone oxidoreductase chain 6 NADH NUBP iron-sulfur cluster assembly factor like Protein arginine methyltransferase NDUFAF7, mitochondrial Transmembrane protein 186	A0A0G2JZF6 A0A8I5Y9A4 A0A8I5ZKJ3 A0A8I5ZWM3 A0A8I6A5D4 A0A8I6AKU6 A0A8I6AL00 A0A8I6B100 B1WC61 B2GV71 B2RZD2 D3ZE15 D3ZF13 D3ZFQ3 D3ZG43 D3ZLT1 D3ZN43 D3ZQH7 D3ZZ21 D4A0T0 D4A3V2 D4A565 D4A7L4 F1LWG4 F1LXA0 F1LZC5 F7ELE5 F7EXQ7 F7F9K9 M0RB63 O08776 P03889 P03926 P05506 P05508 P11661 P11662 P19234 P52504 Q4KLZ1 Q561S0 Q5BK63 Q5XI79 Q5XIC2 Q5XIF3 Q5XIH3 Q63362 Q641Y2 Q66HF1 Q6AY94 Q6PCU8 Q80W89 Q9NQR8	AABR07056686.1 Acad9 Ecsit Hrpap20 Ip13 LOC100363268 LOC100911483 LOC103691107 LOC120101567 LOC684509 Mt-nd1 Mt-nd2 Mt-nd3 Mt-nd4 Mt-nd5 Mt-nd6 Mtnd1 Mtnd4 Mtnd5 Mtnd6 Nd1 Nd2 Nd3 Nd4 Nd5 Nd6 Ndufa10 Ndufa11 Ndufa12 Ndufa13 Ndufa2 Ndufa3-ps3 Ndufa5 Ndufa6 Ndufa8 Ndufa9 Ndufab1 Ndufaf1 Ndufaf2 Ndufaf3 Ndufaf4 Ndufaf5 Ndufaf6 Ndufaf7 Ndufb10 Ndufb11 Ndufb2 Ndufb3 Ndufb4l5 Ndufb5 Ndufb6 Ndufb7 Ndufb8 Ndufc1 Ndufs1 Ndufs2 Ndufs3 Ndufs4 Ndufs5 Ndufs5-ps2 Ndufs6 Ndufs7 Ndufs8 Ndufv1 Ndufv2 Ndufv3 Nubpl Timmdc1 Tmem126b Tmem186	Rattus norvegicus (Norway rat)
Protein lipoylation	Acyl carrier protein Adrenodoxin, mitochondrial Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial Glycine cleavage system H protein, mitochondrial Lipoyl synthase, mitochondrial Lipoyltransferase 1 NFU1 iron-sulfur cluster scaffold homolog, mitochondrial Octanoyl-[acyl-carrier-protein]	A0A8I5ZRJ8 B2GV15 D3Z9Z2 D3ZA85 D3ZF13 P08461 P24483 Q01205 Q5I0P2 Q5XIH4	Dbt Dlat Dlst Fdx1 Gcsh Lias Lipt1 Lipt2 Ndufab1 Nfu1	Rattus norvegicus (Norway rat)
Signaling by BMP	Activin receptor type-2A Activin receptor type-2B Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein receptor type-1A Chordin-like protein 1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Follistatin-related protein 1 Gremlin Growth differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog 7 Mothers against decapentaplegic homolog 9 Mothers against decapentaplegic homolog Muellerian-inhibiting factor Serine/threonine-protein kinase receptor R3 Serine/threonine-protein kinase receptor Ski oncogene Transforming growth factor beta receptor type 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Zinc finger FYVE-type containing 16 receptor protein serine/threonine kinase	A0A0G2K612 A0A0G2K628 A0A8I5Y0P5 A0A8I5ZXN2 A0A8I6AM39 D3ZAQ2 D3ZDK2 D3ZXD0 D4ADF6 M0RB87 O54835 O70437 O88406 P17490 P18331 P26342 P38444 P38445 P49000 P49001 P61078 P80203 P97588 Q4AEG6 Q62632 Q62893 Q76LD0 Q78EA7 Q9R1V3	Actrii Actriib Acvr2 Acvr2a Acvr2b Acvrl1 Acvrlk1 Amh Amhr2 Bmp-2 Bmp10 Bmp2 Bmpr1a Bmpr1b Bmpr2 Chrdl1 Frp Fstl1 Gdf2 Grem2 Inha Inhba Kjr Mad1 Madh1 Madh4 Madh5 Madh7 Madh8 Madh9 Ng1 Ski Smad1 Smad4 Smad5 Smad6 Smad7 Smad8 Smad9 Smurf1 Smurf2 Tgfbr3 Ube2d1 Ube2d3 Zfyve16	Rattus norvegicus (Norway rat)
Signaling by Activin	Activin receptor type-1B Activin receptor type-1C Activin receptor type-2A Activin receptor type-2B Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Transforming growth factor beta receptor type 3	O70436 O70437 P17490 P17491 P18331 P21708 P26342 P38444 P38445 P63086 P70539 P80202 P84025	Actrii Actriib Acvr1b Acvr1c Acvr2 Acvr2a Acvr2b Acvrlk4 Alk4 Alk7 Erk1 Erk2 Inha Inhba Inhbb Madh2 Madh3 Madh4 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Smad2 Smad3 Smad4 Tgfbr3	Rattus norvegicus (Norway rat)
CDC42 GTPase cycle	Active breakpoint cluster region-related protein ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 Breakpoint cluster region protein Caveolin-1 Cell division control protein 42 homolog Chimaerin DEF6 guanine nucleotide exchange factor DEP domain containing 1B Dedicator of cytokinesis 10 Dedicator of cytokinesis 11 Dedicator of cytokinesis 6 Dedicator of cytokinesis 7 Dedicator of cytokinesis 8 Delta(14)-sterol reductase LBR Dynamin-binding protein Ephexin-1 Epithelial cell transforming 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain containing 1 FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 3 FYVE, RhoGEF and PH domain-containing protein 4 Family with sequence similarity 13, member B Gem-interacting protein Guanine nucleotide exchange factor DBS Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kinectin 1 LOC687105 protein MCF.2 cell line derived transforming sequence Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 Pleckstrin homology and RhoGEF domain containing G1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G3 Rac GTPase-activating protein 1 RalA-binding protein 1 Ras-specific guanine nucleotide-releasing factor 2 Rho GDP dissociation inhibitor beta Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 10 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 22 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 33 Rho GTPase activating protein 40 Rho GTPase activating protein 42 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 9 Rho GTPase-activating protein 17 Rho GTPase-activating protein 20 Rho GTPase-activating protein 24 Rho GTPase-activating protein 26 Rho GTPase-activating protein 27 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 44 Rho GTPase-activating protein 7 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 9 SLIT-ROBO Rho GTPase activating protein 1 SLIT-ROBO Rho GTPase activating protein 3 SLIT-ROBO Rho GTPase-activating protein 2 Spermatogenesis associated 13 StAR-related lipid transfer domain containing 13 StAR-related lipid transfer domain containing 8 Synaptobrevin homolog YKT6 T-cell activation RhoGTPase activating protein TIAM Rac1 associated GEF 1 Triple functional domain protein Unconventional myosin-IXb Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3	A0A096MK16 A0A0G2JTR4 A0A0G2JTU0 A0A0G2JV16 A0A0G2JVF0 A0A0G2JVX3 A0A0G2JYR5 A0A0G2K3H2 A0A0G2K7N9 A0A0G2K860 A0A0G2KA11 A0A8I5ZKS6 A0A8I5ZL97 A0A8I5ZMG2 A0A8I5ZPB5 A0A8I5ZRJ5 A0A8I5ZRM9 A0A8I5ZS98 A0A8I5ZXI2 A0A8I6A4W2 A0A8I6A829 A0A8I6A9Q4 A0A8I6AC12 A0A8I6ADN8 A0A8I6AEP6 A0A8I6AL39 A0A8I6ANH8 A0A8I6AP97 A0A8I6APD0 A0A8I6APL5 A0A8I6APV4 A0A8I6AQA1 A0A8I6GDA1 A0A8I6GLR6 B2GUW2 D3Z9I3 D3ZA21 D3ZA46 D3ZCI3 D3ZCK4 D3ZU63 D3ZUD0 D3ZWB4 D3ZWF9 D3ZXG5 D3ZYG0 D3ZZN9 D4A1D2 D4A208 D4A5B9 D4A646 D4A987 D4A9G6 D4AA32 D4AE81 E9PT59 F1LQX4 F1LXF1 F1LYQ8 F1M0Z1 F1M287 F1M5M9 F1MAK3 F7EUE3 G3V9A0 M0R3X3 M0R4F8 O88387 P0CAX5 P41350 P81128 Q5BKC9 Q5EGY4 Q5PQJ5 Q5U2Z7 Q5XI73 Q5XXR3 Q62796 Q63358 Q63406 Q63744 Q63787 Q63788 Q6P720 Q6Q7Y5 Q6REY9 Q6TLK4 Q8CFN2 Q99JE4 Q99N37 Q9ES67 Q9QX73 Q9WVE9	AABR07021955.1 AABR07032856.1 Abr Arap1 Arap2 Arap3 Arhgap1 Arhgap10 Arhgap17 Arhgap20 Arhgap21 Arhgap22 Arhgap24 Arhgap26 Arhgap27 Arhgap29 Arhgap30 Arhgap31 Arhgap32 Arhgap33 Arhgap35 Arhgap4 Arhgap40 Arhgap42 Arhgap44 Arhgap45 Arhgap5 Arhgap7 Arhgap9 Arhgdia Arhgdib Arhgdig Arhgef10 Arhgef11 Arhgef12 Arhgef15 Arhgef16 Arhgef19 Arhgef25 Arhgef26 Arhgef5 Arhgef6 Arhgef9 Bcr Camgap1 Cav Cav1 Cdc42 Def6 Depdc1b Dlc1 Dnmbp Dock10 Dock11 Dock6 Dock7 Dock8 Ect2 Ehsh1 Fam13b Farp1 Fgd1 Fgd2 Fgd3 Fgd4 Geft Gmip Gna13 Grf2 Grlf1 Itsn Itsn1 Ktn1 LOC687105 Lbr Mcf2 Mcf2l Myo9b Myr5 Ngef Ophn1 Ost P190A Pik3r1 Pik3r2 Plekhg1 Plekhg2 Plekhg3 Prex1 Prex2 RGD1565043 Racgap1 Ralbp1 Rasgrf2 Rhogap Rich2 Spata13 Srgap1 Srgap2 Srgap3 Stard12 Stard13 Stard8 Syde1 Tagap Tiam1 Trio Tuba Vav2 Vav3 Ykt6 p190ARHOGAP	Rattus norvegicus (Norway rat)
ATF6B (ATF6-beta) activates chaperones	Activating transcription factor 6 beta Membrane-bound transcription factor site-1 protease	F7ERH6 Q9WTZ3	Atf6b Mbtps1 S1p Ski1	Rattus norvegicus (Norway rat)
CREB phosphorylation	Activating transcription factor 1 Cyclic AMP-responsive element-binding protein 1 MAPK activated protein kinase 2 Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A8I6A7D1 A0A8I6AR08 A0A8I6AWJ2 F7FD47 P15337 Q63531 Q80ZF4	Atf1 Creb-1 Creb1 Mapkapk1a Mapkapk2 Rps6ka1 Rps6ka2 Rps6ka3 Rps6ka5 Rsk1	Rattus norvegicus (Norway rat)

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