GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **926 - 950** of **1070** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Synthesis of PIPs at the Golgi membrane	1-phosphatidylinositol-3-phosphate 5-kinase ADP-ribosylation factor 1 ADP-ribosylation factor 3 Inositol polyphosphate 5-phosphatase OCRL Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase alpha Phosphatidylinositol 4-kinase beta Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol polyphosphate 5-phosphatase type IV Phosphatidylinositol-3-phosphatase SAC1 Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Phosphoinositide 3-kinase regulatory subunit 4 Protein VAC14 homolog Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2	A0A8I5YBG1 D3ZGS3 D3ZTF6 D4ADC8 O08561 O08662 O70173 O88763 P0C0R5 P61206 P84079 Q5XIL2 Q80W92 Q99M64 Q9ES21 Q9WVR1	Arf1 Arf3 Inpp5e Ocrl Pi4k2a Pi4k2b Pi4ka Pi4kb Pi4kii Pik3c2a Pik3c2g Pik3c3 Pik3r4 Pik4ca Pik4cb Pikfyve Sac1 Sacm1l Tpte Tpte2 Vac14 Vps34	Rattus norvegicus (Norway rat)
Synthesis of PIPs at the early endosome membrane	1-phosphatidylinositol-3-phosphate 5-kinase Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase F Myotubularin-related protein 12 Myotubularin-related protein 2 Myotubularin Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Phosphoinositide 3-kinase regulatory subunit 4 Protein VAC14 homolog Type II inositol 3,4-bisphosphate 4-phosphatase protein-tyrosine-phosphatase	A0A8I5YBG1 A0A8I5ZTB8 A0A8I6AFY1 D3ZKG7 D3ZTF6 O88763 P0C0R5 Q5FVM6 Q5XIL2 Q62784 Q6AXQ4 Q80W92 Q99M64 Q9QWG5	Inpp4a Inpp4b Inpp5f Mtm1 Mtmr12 Mtmr2 Mtmr4 Pi4k2a Pi4k2b Pi4kii Pik3c2a Pik3c3 Pik3r4 Pikfyve Pip3ap Vac14 Vps34	Rattus norvegicus (Norway rat)
Synthesis of PIPs at the plasma membrane	ADP-ribosylation factor 1 Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase K Myotubularin related protein 14 Myotubularin-related protein 3 Myotubularin-related protein 6 Myotubularin Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide-3-kinase, regulatory subunit 6 Pleckstrin homology domain containing A1 Pleckstrin homology domain containing A2 Pleckstrin homology domain containing A5 Pleckstrin homology domain containing A6 Pleckstrin homology domain-containing family A member 4 Pleckstrin homology domain-containing family A member 8 RUN and FYVE domain containing 1 Ras-related protein Rab-14 Ras-related protein Rab-4A Ras-related protein Rab-5A Sesquipedalian Synaptojanin-1 Synaptojanin-2 Type II inositol 3,4-bisphosphate 4-phosphatase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 13 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2JXT6 A0A0G2K1A8 A0A0G2K1Q0 A0A0G2K2Z2 A0A0G2K344 A0A8I5Y1D5 A0A8I5Y949 A0A8I5ZTX1 A0A8I6AKY1 A0A8I6AU71 A0A8I6G5K9 A0A8I6G942 D3ZFJ0 D3ZGS3 D3ZMA2 D3ZSI8 D3ZTF6 D3ZY60 D4A4I3 E9PTG5 F1LR42 F1LVI0 G3V9S3 M0RC99 O55207 O70173 O88370 O88377 P05714 P60669 P61107 P84079 P97573 Q5CZZ9 Q5I6B8 Q5PQT2 Q5XIL2 Q62784 Q62910 Q63787 Q63788 Q63789 Q6AXQ4 Q99M64 Q9JMC1 Q9QWG5 Q9R0I8 Q9WVR3 Q9Z1L0	Arf1 Bmx Fapp2 Inpp4a Inpp4b Inpp5d Inpp5j Inpp5k Inppl1 Mtm1 Mtmr1 Mtmr14 Mtmr3 Mtmr6 Ocrl Pepp1 Pi4k2a Pi4k2b Pi4kii Pib5pa Pik3c2a Pik3c2b Pik3c2g Pik3ca Pik3cb Pik3cd Pik3cg Pik3r1 Pik3r2 Pik3r3 Pik3r5 Pik3r6 Pip4k2a Pip4k2b Pip4k2c Pip4ka Pip5k1a Pip5k1b Pip5k1c Pip5k2a Pip5k2b Pip5k2c Pipp Plekha1 Plekha2 Plekha3 Plekha4 Plekha5 Plekha6 Plekha8 Pten Ptpn13 Rab14 Rab4 Rab4a Rab5a Rufy1 Ship Ship1 Ship2 Synj1 Synj2	Rattus norvegicus (Norway rat)
Synthesis of PS	Phosphatidylserine synthase 1 Phosphatidylserine synthase 2	B2GV22 Q5PQL5	Ptdss1 Ptdss2	Rattus norvegicus (Norway rat)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1, member C1 Carbonyl reductase [NADPH] 1 Cytochrome P450 family 8 subfamily B member 1 Hematopoietic prostaglandin D synthase Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase 3 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin-H2 D-isomerase Thromboxane-A synthase	D4AE56 G3V8J2 O35543 P22057 P35355 P47727 P49430 P83868 Q3MHS3 Q62969 Q63921 Q6AYQ2 Q9JHF3	Akr1c1 Akr1c21 Cbr Cbr1 Cox-1 Cox-2 Cox1 Cox2 Cyp5 Cyp5a1 Cyp8 Cyp8b1 Gsts Hpgds Hsd17b5 Pgds Pges Pig12 Ptgds Ptgds2 Ptges Ptges2 Ptges3 Ptgis Ptgs1 Ptgs2 Tbxas1 Tebp	Rattus norvegicus (Norway rat)
Synthesis of UDP-N-acetyl-glucosamine	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 N-acetyl-D-glucosamine kinase N-acetylglucosamine-6-phosphate deacetylase N-acylglucosamine 2-epimerase Phosphoacetylglucosamine mutase UDP-N-acetylglucosamine pyrophosphorylase 1	B2RYN0 D3ZF39 P51607 P81799 P82808 Q4KMC4 Q5BJY6	Amdhd2 Gfpt1 Gfpt2 Nagk Pgm3 Renbp Uap1	Rattus norvegicus (Norway rat)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	Cell division cycle 34, ubiqiutin conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme N-terminal E2 ubiquitin-conjugating enzyme Polyubiquitin-B Polyubiquitin-C Ubiquitin B-like Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase isozyme L3 Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 Q2 Ubiquitin-conjugating enzyme E2 B Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 G1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-conjugating enzyme E2 Z Ubiquitin-conjugating enzyme E2A Ubiquitin-conjugating enzyme E2R 2 Ubiquitin-like modifier activating enzyme 6 Ubiquitin-like modifier-activating enzyme 1 Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A8I5YBM5 A0A8I6A356 A0A8I6A5Y3 A0A8I6A8J6 A0A8J8Y4N8 B0BMY6 B5DFI8 D3Z8W5 D3ZDK2 D3ZUW6 D3ZVQ0 D4A1G2 D4A453 D4A8H3 F1M3L4 F7F5A1 G3V6M7 M0R4P9 M0R6B6 P0CG51 P62255 P62839 P62982 P63149 Q3B7D1 Q4VSI4 Q5U300 Q63429 Q91Y78	AABR07041109.1 Cdc34 Fam105b Hausp LOC100360645 LOC100362554 LOC100366017 LOC64038 NEWGENE_1308361 Otulin Rad6b Rps27a Uba1 Uba6 Uba80 Ubb Ubbl1 Ubc Ubc4 Ubc7 Ubcep1 Ubch4 Ubch5b Ubcl1 Ube1 Ube2a Ube2b Ube2c Ube2d1 Ube2d2 Ube2e1 Ube2e3 Ube2g Ube2g1 Ube2g2 Ube2h Ube2k Ube2l3 Ube2q2 Ube2r2 Ube2s Ube2t Ube2w Ube2z Uchl3 Usp5 Usp7	Rattus norvegicus (Norway rat)
Synthesis of bile acids and bile salts	25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) Bile acid receptor Cholesterol 25-hydroxylase Cytochrome P450 7A1 Nuclear receptor coactivator 2 Nuclear receptor coactivator Oxysterol-binding protein-related protein 1 Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Retinoic acid receptor RXR-alpha	A0A8I6AI28 A0A8I6ANM6 A0A8I6APA0 D3ZHZ3 D4A0F3 D4A0G0 D4A9D8 P18125 Q05343 Q4QQV7 Q62735 Q63688 Q8K4M9 Q9WUI9	Bar Ch25h Cyp7 Cyp7a1 Cyp7b1 Fxr Ncoa1 Ncoa2 Nr1h4 Nr2b1 Orp1 Osbp Osbpl1a Osbpl2 Osbpl3 Osbpl6 Osbpl7 Osbpl9 Rip14 Rxra Tif2	Rattus norvegicus (Norway rat)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol	25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) 3 beta-hydroxysteroid dehydrogenase type 7 Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1 member D1 Aldo-keto reductase family 1, member C1 Bile acid receptor Cytochrome P450 7A1 Cytochrome P450 family 8 subfamily B member 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator Prostacyclin synthase Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial	A0A8I6APA0 G3V8J2 O35048 P17178 P18125 P31210 Q05343 Q3MHS3 Q62735 Q62969 Q63688 Q6AYQ2 Q9WUI9	Akr1c1 Akr1c21 Akr1d1 Bar Cca2 Cyp27 Cyp27a1 Cyp7 Cyp7a1 Cyp7b1 Cyp8 Cyp8b1 Fxr Hsd17b5 Hsd3b7 Ncoa1 Ncoa2 Nr1h4 Nr2b1 Ptgis Rip14 Rxra Tif2	Rattus norvegicus (Norway rat)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) 3 beta-hydroxysteroid dehydrogenase type 7 Acyl-coenzyme A thioesterase 8 Aldo-keto reductase family 1 member C21 Aldo-keto reductase family 1 member D1 Aldo-keto reductase family 1, member C1 Alpha-methylacyl-CoA racemase Bile acid receptor Bile acid-CoA Bile salt export pump Cytochrome P450 7A1 Cytochrome P450 family 8 subfamily B member 1 Long-chain fatty acid transport protein 2 Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 2 Nuclear receptor coactivator Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal multifunctional enzyme type 2 Prostacyclin synthase Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial Sterol carrier protein 2	A0A8I6APA0 G3V8J2 O35048 O70127 P11915 P17178 P18125 P31210 P70473 P97524 P97562 P97852 Q05343 Q3MHS3 Q62735 Q62969 Q63276 Q63688 Q6AYQ2 Q8VHK0 Q9ES38 Q9WUI9	Abcb11 Acot8 Acox2 Acsb Acsvl1 Akr1c1 Akr1c21 Akr1d1 Amacr Baat Bar Bsep Cca2 Cyp27 Cyp27a1 Cyp7 Cyp7a1 Cyp7b1 Cyp8 Cyp8b1 Edh17b4 Facvl1 Fatp2 Fatp5 Fxr Hsd17b4 Hsd17b5 Hsd3b7 Ncoa1 Ncoa2 Nr1h4 Nr2b1 Pte1 Ptgis Rip14 Rxra Scp-2 Scp2 Slc27a2 Slc27a5 Spgp Thcox Tif2 Vlacs Vlacsr Vlcs	Rattus norvegicus (Norway rat)
Synthesis of diphthamide-EEF2	Diphthine--ammonia ligase Elongation factor 2 diphthine methyl ester synthase	A0A8I5ZL86 P05197 Q5M9F5	Atpbd4 Dph5 Dph6 Eef2	Rattus norvegicus (Norway rat)
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	Bifunctional epoxide hydrolase 2 Cytochrome P450 1A1 Cytochrome P450 1A2 Cytochrome P450 1B1 Cytochrome P450 2C26-like Cytochrome P450 2J3 Cytochrome P450, family 2, subfamily j, polypeptide 16	A0A0G2JTQ9 A0A8I6AFV7 P00185 P04799 P51590 P80299 Q64678	Cyp1a-1 Cyp1a-2 Cyp1a1 Cyp1a2 Cyp1b1 Cyp2c66 Cyp2j16 Cyp2j3 Cyp2j9 Ephx2 LOC100912265	Rattus norvegicus (Norway rat)
Synthesis of glycosylphosphatidylinositol (GPI)	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol phosphate-mannose biosynthesis regulatory protein GPI ethanolamine phosphate transferase 1 GPI ethanolamine phosphate transferase 2 GPI mannosyltransferase 1 GPI mannosyltransferase 2 Mannosyltransferase N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase Phosphatidylinositol N-acetylglucosaminyltransferase subunit C Phosphatidylinositol glycan anchor biosynthesis, class F Phosphatidylinositol glycan anchor biosynthesis, class H Phosphatidylinositol glycan anchor biosynthesis, class P Phosphatidylinositol glycan anchor biosynthesis, class Q Phosphatidylinositol-glycan biosynthesis class W protein Phosphatidylinositol-glycan biosynthesis class X protein phosphatidylinositol N-acetylglucosaminyltransferase	A0A0G2K579 A0A8I5ZK79 A0A8I6A044 A0A8I6AHS9 D3ZYY8 D4AAY7 E9PTA5 M0R9J2 O35790 Q5KR61 Q5PQQ4 Q60GF7 Q642B8 Q7TSN4 Q9EQY6 Q9Z325	Dpm2 Piga Pigb Pigc Pigf Pigg Pigh Pigl Pigm Pign Pigp Pigq Pigv Pigw Pigx	Rattus norvegicus (Norway rat)
Synthesis of very long-chain fatty acyl-CoAs	17-beta-hydroxysteroid dehydrogenase type 3 Acyl-CoA synthetase family member 3 Elongation of very long chain fatty acids protein 1 Elongation of very long chain fatty acids protein 3 Fatty acid CoA ligase Acsl3 Long-chain-fatty-acid--CoA ligase 1 Long-chain-fatty-acid--CoA ligase 4 Long-chain-fatty-acid--CoA ligase 5 Long-chain-fatty-acid--CoA ligase 6 Long-chain-fatty-acid--CoA ligase ACSBG1 Long-chain-fatty-acid--CoA ligase ACSBG2 Trans-2,3-enoyl-CoA reductase-like Very long chain fatty acid elongase 2 Very long chain fatty acid elongase 5 Very long chain fatty acid elongase 6 Very long chain fatty acid elongase 7 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain 3-oxoacyl-CoA reductase Very-long-chain enoyl-CoA reductase	A0A1B0GWP1 A0A8I5ZQB2 A0A8I6AU59 A1L1K7 D3ZPX9 D3ZUX7 D4A1Y9 D4A612 D4ABI7 D4ADY9 O35547 O54939 O88813 P18163 P33124 Q63151 Q64232 Q6P7R8 Q920L6 Q920L7 Q924N5	Acs1 Acs2 Acs3 Acs4 Acs5 Acsbg1 Acsbg2 Acsf3 Acsl1 Acsl2 Acsl3 Acsl4 Acsl5 Acsl6 ELOVL1 ELOVL3 Edh17b3 Elovl1 Elovl2 Elovl3 Elovl5 Elovl6 Elovl7 Face Facl2 Facl3 Facl4 Facl5 Facl6 Gpsn2 Grlacs Hacd1 Hacd3 Hacd4 Hsd17b12 Hsd17b3 LOC100365676 Lce Ssc2 Tecr Tecrl	Rattus norvegicus (Norway rat)
Synthesis, secretion, and deacylation of Ghrelin	Appetite-regulating hormone Carboxylic ester hydrolase Ghrelin O-acyltransferase Insulin-1 Insulin-like growth factor I Leptin Neuroendocrine convertase 1 Pro-glucagon Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Somatotropin	A0A8J8XQI9 B1Q005 D3ZD11 D3ZF12 D3ZFK5 P01244 P01322 P06883 P08025 P28840 P42667 P50596 Q9QYH7 Q9WTR7	Bche Bdp Gcg Gh Gh1 Ghrl Goat Igf-1 Igf1 Ins-1 Ins1 Lep Mboat4 Nec-1 Nec1 Ob Pcsk1 Sec11a Sec11c Sec11l1 Sec11l3 Spc18 Spc21 Spcs1 Spcs2 Spcs3	Rattus norvegicus (Norway rat)	G58161NS
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Free fatty acid receptor 4 Gastrin-releasing peptide Glucose-dependent insulinotropic receptor Leptin Pro-glucagon	P06883 P14740 P24393 P50596 Q2AC31 Q7TQN8 Q8K3T4	Cd26 Dpp4 Ffar1 Ffar4 Gcg Gpr119 Gpr120 Gpr40 Grp Lep O3far1 Ob	Rattus norvegicus (Norway rat)	G58161NS
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Gastric inhibitory polypeptide Glucose-dependent insulinotropic receptor	P14740 Q06145 Q7TQN8 Q8K3T4	Cd26 Dpp4 Ffar1 Gip Gpr119 Gpr40	Rattus norvegicus (Norway rat)
TAK1-dependent IKK and NF-kappa-B activation	Advanced glycosylation end product-specific receptor Amyloid-beta precursor protein High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor-interacting Ras-like protein 2 NFKB inhibitor interacting Ras-like 1 Nuclear factor kappa B subunit 2 Protein S100-B RELA proto-oncogene, NF-kB subunit	A0A0G2K6P4 A0A8I5Y7D7 A0A8I5ZMV7 A0A8I6AH74 A0A8I6ANR6 A0A8I6APQ3 A0A8I6G6F3 A0A8I6GBU6 D3ZCK2 P04631 P08592 P63159 Q63495 Q63746 Q6TMG5 Q9JIA3 Q9QY78	A4 AD1 Ager App Chuk Hmg-1 Hmg1 Hmgb1 Hmgb1-ps33 Hmgb1-ps4 Hmgb1l1 Hmgb1l2 Hmgb1l3 Hmgb1l5 Ikba Ikbb Ikbkb Ikbkg Ikkb LOC108349189 LOC108350839 Nemo Nfkb2 Nfkbia Nfkbib Nkiras1 Nkiras2 Rage Rela S100b	Rattus norvegicus (Norway rat)
TCF dependent signaling in response to WNT	Axin-1 Axin-2 Catenin beta-1 E3 ubiquitin-protein ligase RNF146 Poly [ADP-ribose] polymerase Poly [ADP-ribose] polymerase Polyubiquitin-B Polyubiquitin-C Protein Wnt-5a Protein Wnt Protein Wnt Protein Wnt Protein kinase-related protein Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A0G2JTB0 A0A8I5ZVK3 A0A8I6A5Y3 A0A8I6AN69 D3Z8Q6 D4A9J2 F1M077 O70239 O70240 P0CG51 P62982 Q5XIK5 Q63429 Q6BC88 Q9QXQ7 Q9WU82	Axin Axin1 Axin2 Catnb Ctnnb1 LOC100360645 Rnf146 Rps27a Ryk Tnks Tnks2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Usp34 Wnt-5a Wnt1 Wnt3 Wnt3a Wnt5a	Rattus norvegicus (Norway rat)
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Myc proto-oncogene protein Transcription factor AP-2 gamma [histone H3]-trimethyl-L-lysine(4) demethylase	A0A0G2K3N6 F7EWS2 P09416	Kdm5b Myc Tfap2c	Rattus norvegicus (Norway rat)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family, AAA domain containing 2 Estrogen receptor Glycoprotein hormones alpha chain Lutropin subunit beta	A0A8I5ZNS1 P01230 P06211 P11962	Atad2 Cga Cga1 Esr Esr1 Estr Lhb Nr3a1	Rattus norvegicus (Norway rat)
TGF-beta receptor signaling activates SMADs	E3 ubiquitin-protein ligase CBL Furin Integrin beta-1 Integrin beta-3 Integrin beta-6 Integrin beta Integrin beta Integrin subunit alpha 8 Integrin subunit alpha V Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Latent-transforming growth factor beta-binding protein 1 Latent-transforming growth factor beta-binding protein 2 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NEDD8 Peptidyl-prolyl cis-trans isomerase FKBP1A TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor type 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein Ubiquitin-conjugating enzyme E2M Zinc finger FYVE domain-containing protein	A0A0G2JVU1 A0A8I5ZYZ8 A0A8I6AQL1 A0A8I6AVC5 A0A8I6G3R2 D3ZDC7 D4A917 F1LZX9 F7F1E3 O35806 O70436 O70437 P17246 P23377 P26342 P38438 P49134 P80204 P84025 Q00918 Q07257 Q07258 Q62658 Q6AYF4 Q71UE8 Q8R2H2	Cbl Fkbp1 Fkbp1a Fur Furin Itga8 Itgav Itgb1 Itgb3 Itgb5 Itgb6 Itgb8 Ltbp1 Ltbp2 Ltbp3 Ltbp4 Madh2 Madh3 Madh4 Nedd8 Pcsk3 Smad2 Smad3 Smad4 Tgf-b3 Tgfb1 Tgfb2 Tgfb3 Tgfbr1 Tgfbr2 Tgfbr3 Ube2m Zfyve9	Rattus norvegicus (Norway rat)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Polyubiquitin-B Polyubiquitin-C Protein kinase C zeta type TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein	A0A0G2K612 A0A8I6A4L9 A0A8I6A5Y3 P09217 P0CG51 P17246 P38438 P61589 P62982 P80204 Q63429 Q6B4M5 Q9JHY1 Q9Z340	Arha Arha2 Cgn F11r Jam1 LOC100360645 Par-6a Par3 Par6a Pard3 Pard6a Pkcz Prkcz Rhoa Rps27a Smurf1 Tgfb1 Tgfbr1 Tgfbr2 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1	Rattus norvegicus (Norway rat)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Baculoviral IAP repeat-containing 2 Baculoviral IAP repeat-containing 3 CD40 ligand Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor superfamily member 11A TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 12 TNF superfamily member 13b TNF superfamily member 14 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor receptor superfamily member 5	A0A0G2JTI9 A0A0G2K7X2 A0A0U5J4Y0 A0A8I6AHI1 A0A8I6GJT5 B5DFH7 D3ZFD8 D3ZTD1 D4A281 F1M8Z6 G3V6F9 M0RCN2 Q06332 Q6MG45 Q6P6S1 Q9ESE2 Q9Z2V2	Birc2 Birc3 Cd40 Cd40l Cd40lg Lta Ltb Ltbr Map3k14 Opgl Rankl Tnfb Tnfrsf11a Tnfrsf12a Tnfrsf13c Tnfsf1 Tnfsf11 Tnfsf12 Tnfsf13b Tnfsf14 Tnfsf5 Tnlg1d Tnlg4a Traf2 Traf3 Trance	Rattus norvegicus (Norway rat)
TNF signaling	BAG cochaperone 4 Disintegrin and metalloproteinase domain-containing protein 17 Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor	A0A8I6AP78 B5DFH7 D3ZYL0 D3ZZC5 P16599 P22934 Q9Z1K9	Adam17 Bag4 Ripk1 Tace Tnf Tnfa Tnfr-1 Tnfr1 Tnfrsf1a Tnfsf2 Tradd Traf2	Rattus norvegicus (Norway rat)

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