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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
alcohol dependence
Summary
- Synonym
-
- alcoholism
- Definition
- A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.
- Super Class
- substance dependence
External Links
- Disease Ontology
- DOID:0050741
- Mondo Disease Ontology
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 125 | ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | |
| 126 | ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | |
| 127 | ADH4 | alcohol dehydrogenase 4 (class II), pi polypeptide | |
| 150 | ADRA2A | adrenoceptor alpha 2A | |
| 196 | AHR | aryl hydrocarbon receptor | |
| 217 | ALDH2 | aldehyde dehydrogenase 2 family member | |
| 284 | ANGPT1 | angiopoietin 1 | |
| 367 | AR | androgen receptor | |
| 406 | BMAL1 | basic helix-loop-helix ARNT like 1 | |
| 627 | BDNF | brain derived neurotrophic factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 50779 | Rgs6 | regulator of G-protein signaling 6 | |
| 53322 | Nucb2 | nucleobindin 2 | |
| 54393 | Gabbr1 | gamma-aminobutyric acid type B receptor subunit 1 | |
| 63959 | Slc29a1 | solute carrier family 29 (nucleoside transporters), member 1 | |
| 72508 | Rps6kb1 | ribosomal protein S6 kinase, polypeptide 1 | |
| 98741 | Kcnb2 | potassium voltage gated channel, Shab-related subfamily, member 2 | |
| 108043 | Chrnb3 | cholinergic receptor, nicotinic, beta polypeptide 3 | |
| 110834 | Chrna3 | cholinergic receptor, nicotinic, alpha polypeptide 3 | |
| 232333 | Slc6a1 | solute carrier family 6 (neurotransmitter transporter, GABA), member 1 | |
| 239528 | Ago2 | argonaute RISC catalytic subunit 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24239 | Cacna1c | calcium voltage-gated channel subunit alpha1 C | |
| 24267 | Comt | catechol-O-methyltransferase | |
| 24318 | Drd2 | dopamine receptor D2 | |
| 24409 | Grin2a | glutamate ionotropic receptor NMDA type subunit 2A | |
| 24473 | Htr1a | 5-hydroxytryptamine receptor 1A | |
| 24586 | Ncam1 | neural cell adhesion molecule 1 | |
| 24596 | Ngfr | nerve growth factor receptor | |
| 24613 | Oprd1 | opioid receptor, delta 1 | |
| 24922 | Gabrb3 | gamma-aminobutyric acid type A receptor subunit beta 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31251 | per | period | |
| 31309 | dnc | dunce | |
| 31364 | Fas2 | Fasciclin 2 | |
| 32554 | Lcch3 | Ligand-gated chloride channel homolog 3 | |
| 32674 | RSG7 | Regulator of G-protein signaling 7 | |
| 33007 | Dop2R | Dopamine 2-like receptor | |
| 34950 | Ca-alpha1D | Ca[2+]-channel protein alpha[[1]] subunit D | |
| 36411 | sca | scabrous | |
| 36849 | DAT | Dopamine transporter | |
| 37191 | 5-HT1B | 5-hydroxytryptamine (serotonin) receptor 1B |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373802 | pomc.S | proopiomelanocortin S homeolog | Xenopus laevis (African clawed frog) | |
| 378584 | drd2.L | dopamine receptor D2 L homeolog | Xenopus laevis (African clawed frog) | |
| 378605 | htr1a.L | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog | Xenopus laevis (African clawed frog) | |
| 380532 | pomc.L | proopiomelanocortin L homeolog | Xenopus laevis (African clawed frog) | |
| 397761 | ncam1.S | neural cell adhesion molecule 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 397762 | ncam1.L | neural cell adhesion molecule 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 779087 | gdnf.L | glial cell derived neurotrophic factor L homeolog | Xenopus laevis (African clawed frog) | |
| 100127346 | grin2a.L | glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog | Xenopus laevis (African clawed frog) | |
| 100488055 | cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | Xenopus tropicalis (tropical clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171619 | C53D5.5 | Gamma-glutamyltranspeptidase 1 | |
| 172105 | unc-38 | Acetylcholine receptor subunit alpha-type unc-38 | |
| 172150 | unc-63 | Acetylcholine receptor subunit alpha-type unc-63 | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 176304 | dat-1 | Sodium-dependent dopamine transporter | |
| 176691 | gab-1 | Gamma-aminobutyric acid receptor subunit beta | |
| 177911 | Y43C5A.2 | Fibrinogen C-terminal domain-containing protein | |
| 177940 | egl-21 | Carboxypeptidase E | |
| 178269 | lev-1 | Acetylcholine receptor subunit beta-type lev-1 | |
| 179347 | dop-2 | Dopamine receptor 2 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
