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Standards Ontologies Notations
pre-eclampsia

Summary
Synonym
  • gestational hypertension
  • hypertension induced by pregnancy
  • pre-eclamptic toxaemia
  • preeclampsia
  • preeclampsia/eclampsia
  • pregnancy associated hypertension
  • pregnancy toxemia
  • proteinuric hypertension of pregnancy
  • toxaemia of pregnancy
Definition
A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy.
Super Class
hypertension
Disease Ontology
DOID:10591
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 99 in total
Gene ID Gene Symbol Description Source
93 ACVR2B activin A receptor type 2B
118 ADD1 adducin 1
183 AGT angiotensinogen
213 ALB albumin
355 FAS Fas cell surface death receptor
356 FASLG Fas ligand
493 ATP2B4 ATPase plasma membrane Ca2+ transporting 4
718 C3 complement C3
793 CALB1 calbindin 1
953 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
Displaying entries 21 - 30 of 91 in total
Gene ID Gene Symbol Description Source
14254 Flt1 FMS-like tyrosine kinase 1
14473 Gc vitamin D binding protein
14775 Gpx1 glutathione peroxidase 1
14961 H2-Ab1 histocompatibility 2, class II antigen A, beta 1
14964 H2-D1 histocompatibility 2, D region locus 1
14972 H2-K1 histocompatibility 2, K1, K region
15006 H2-Q1 histocompatibility 2, Q region locus 1
15007 H2-Q10 histocompatibility 2, Q region locus 10
15013 H2-Q2 histocompatibility 2, Q region locus 2
15015 H2-Q4 histocompatibility 2, Q region locus 4
Displaying entries 1 - 10 of 47 in total
Gene ID Gene Symbol Description Source
24170 Add1 adducin 1
24179 Agt angiotensinogen
24232 C3 complement C3
24267 Comt catechol-O-methyltransferase
24310 Ace angiotensin I converting enzyme
24464 Hp haptoglobin
24536 Lepr leptin receptor
24600 Nos3 nitric oxide synthase 3
24617 Serpine1 serpin family E member 1
24648 Serpina1 serpin family A member 1
Displaying entries 11 - 18 of 18 in total
Gene ID Gene Symbol Description Source
36693 ItgaPS4 Integrin alphaPS4 subunit
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
37455 Egfr Epidermal growth factor receptor
37732 ItgaPS5 Integrin alphaPS5 subunit
38109 Glut1 Glucose transporter 1
43222 Tl Toll
326235 Cubn Cubilin
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
561372 comta catechol-O-methyltransferase a
565370 comtb catechol-O-methyltransferase b
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying all 4 entries
Gene ID Gene Symbol Description Source Organism
373662 ccn3.L cellular communication network factor 3 L homeolog Xenopus laevis (African clawed frog)
378526 f2r.L coagulation factor 2 (thrombin) receptor L homeolog Xenopus laevis (African clawed frog)
399277 acvr2b.L activin A receptor type 2B L homeolog Xenopus laevis (African clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175781 daf-4 Cell surface receptor daf-4;Serine/threonine-protein kinase receptor;receptor protein serine/threonine kinase
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
177372 cpi-1 Cystatin cpi-1
178672 srp-3 Serpin domain-containing protein
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179729 cubn-1 Cubilin homolog
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
Displaying all 8 entries
Gene ID Gene Symbol Description Source
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
851977 CTS2 putative chitinase
852543 VVS1 Vvs1p
852546 GPX2 glutathione peroxidase GPX2
853770 BUD2 GTPase-activating protein BUD2
853842 GPX1 glutathione peroxidase GPX1
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
854942 OGG1 8-oxoguanine glycosylase OGG1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024