Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 106 in total
Gene ID Gene Symbol Description Source
2056 EPO erythropoietin
2521 FUS FUS RNA binding protein
2638 GC GC vitamin D binding protein
2890 GRIA1 glutamate ionotropic receptor AMPA type subunit 1
2891 GRIA2 glutamate ionotropic receptor AMPA type subunit 2
2892 GRIA3 glutamate ionotropic receptor AMPA type subunit 3
2893 GRIA4 glutamate ionotropic receptor AMPA type subunit 4
2897 GRIK1 glutamate ionotropic receptor kainate type subunit 1
2898 GRIK2 glutamate ionotropic receptor kainate type subunit 2
2899 GRIK3 glutamate ionotropic receptor kainate type subunit 3
Displaying entries 41 - 50 of 73 in total
Gene ID Gene Symbol Description Source
30960 Vapa vesicle-associated membrane protein, associated protein A
50767 Pnpla6 patatin-like phospholipase domain containing 6
53357 Pla2g6 phospholipase A2, group VI
53623 Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3)
54609 Ubqln2 ubiquilin 2
55963 Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
56434 Tspan3 tetraspanin 3
67095 Trak1 trafficking protein, kinesin binding 1
69597 Afg3l2 AFG3-like AAA ATPase 2
70417 Megf10 multiple EGF-like-domains 10
Displaying entries 1 - 10 of 33 in total
Gene ID Gene Symbol Description Source
24335 Epo erythropoietin
24408 Grin1 glutamate ionotropic receptor NMDA type subunit 1
24767 Scnn1b sodium channel epithelial 1 subunit beta
24768 Scnn1g sodium channel epithelial 1 subunit gamma
24849 Tpi1 triosephosphate isomerase 1
25122 Scnn1a sodium channel epithelial 1 subunit alpha
25550 Slc1a1 solute carrier family 1 member 1
25721 Got2 glutamic-oxaloacetic transaminase 2
29482 Slc1a2 solute carrier family 1 member 2
29483 Slc1a3 solute carrier family 1 member 3
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
38742 GluRIA Glutamate receptor IA
38895 Sarm Sterile alpha and Armadillo motif
39836 st scarlet
40665 Nmdar1 NMDA receptor 1
43582 Tpi Triose phosphate isomerase
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1
About Release Notes Help Feedback
International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.1.0

Last updated: December 9, 2024