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Standards Ontologies Notations
neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 31 - 40 of 106 in total
Gene ID Gene Symbol Description Source
5444 PON1 paraoxonase 1
5445 PON2 paraoxonase 2
5446 PON3 paraoxonase 3
5684 PSMA3 proteasome 20S subunit alpha 3
5686 PSMA5 proteasome 20S subunit alpha 5
5689 PSMB1 proteasome 20S subunit beta 1
5704 PSMC4 proteasome 26S subunit, ATPase 4
5708 PSMD2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2
5727 PTCH1 patched 1
5921 RASA1 RAS p21 protein activator 1
Displaying entries 51 - 60 of 73 in total
Gene ID Gene Symbol Description Source
70827 Trak2 trafficking protein, kinesin binding 2
72961 Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
73182 Pear1 platelet endothelial aggregation receptor 1
74244 Atg7 autophagy related 7
94232 Ubqln4 ubiquilin 4
97064 Wwtr1 WW domain containing transcription regulator 1
108099 Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
140919 Slc17a6 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
214058 Megf11 multiple EGF-like-domains 11
216227 Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
Displaying entries 1 - 10 of 33 in total
Gene ID Gene Symbol Description Source
24335 Epo erythropoietin
24408 Grin1 glutamate ionotropic receptor NMDA type subunit 1
24767 Scnn1b sodium channel epithelial 1 subunit beta
24768 Scnn1g sodium channel epithelial 1 subunit gamma
24849 Tpi1 triosephosphate isomerase 1
25122 Scnn1a sodium channel epithelial 1 subunit alpha
25550 Slc1a1 solute carrier family 1 member 1
25721 Got2 glutamic-oxaloacetic transaminase 2
29482 Slc1a2 solute carrier family 1 member 2
29483 Slc1a3 solute carrier family 1 member 3
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
38742 GluRIA Glutamate receptor IA
38895 Sarm Sterile alpha and Armadillo motif
39836 st scarlet
40665 Nmdar1 NMDA receptor 1
43582 Tpi Triose phosphate isomerase
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024