neurodegenerative disease

Summary
Synonym
  • degenerative disease
Definition
A central nervous system disease that results in the progressive deterioration of function or structure of neurons.
Super Class
central nervous system disease
Disease Ontology
DOID:1289
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 51 - 60 of 106 in total
Gene ID Gene Symbol Description Source
6511 SLC1A6 solute carrier family 1 member 6
6512 SLC1A7 solute carrier family 1 member 7
6789 STK4 serine/threonine kinase 4
6908 TBP TATA-box binding protein
7102 TSPAN7 tetraspanin 7
7167 TPI1 triosephosphate isomerase 1
7223 TRPC4 transient receptor potential cation channel subfamily C member 4
7224 TRPC5 transient receptor potential cation channel subfamily C member 5
7353 UFD1 ubiquitin recognition factor in ER associated degradation 1
7415 VCP valosin containing protein
Displaying entries 11 - 20 of 73 in total
Gene ID Gene Symbol Description Source
14810 Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1)
15382 Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1
16573 Kif5b kinesin family member 5B
16798 Lats1 large tumor suppressor
17169 Mark3 MAP/microtubule affinity regulating kinase 3
17758 Map4 microtubule-associated protein 4
17762 Mapt microtubule-associated protein tau
18033 Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
18979 Pon1 paraoxonase 1
19167 Psma3 proteasome subunit alpha 3
Displaying entries 31 - 33 of 33 in total
Gene ID Gene Symbol Description Source
312382 Abcg2 ATP binding cassette subfamily G member 2
316085 Trak1 trafficking kinesin protein 1
317396 Ubqln2 ubiquilin 2
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
31902 Gga Golgi-localized, gamma-adaptin ear containing, ARF binding protein
33627 ft fat
33658 FIG4 FIG4 phosphoinositide 5-phosphatase
35784 Nup50 Nucleoporin 50kD
35851 ptc patched
36484 AttC Attacin-C
36635 Dro Drosocin
38218 drpr draper
38419 Drs Drosomycin
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
192309 tpi1a triosephosphate isomerase 1a
403143 sarm1 sterile alpha and TIR motif containing 1
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
407667 asic4b acid-sensing (proton-gated) ion channel family member 4b
407668 asic4a acid-sensing (proton-gated) ion channel family member 4a
407669 asic2 acid-sensing (proton-gated) ion channel 2
407670 asic1c acid-sensing (proton-gated) ion channel 1c
407672 asic1b acid-sensing (proton-gated) ion channel 1b
436718 rhocb ras homolog family member Cb
Displaying all 3 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
173064 ced-1 Cell death abnormality protein 1
173631 ptc-3 Protein patched homolog 3
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
175502 tir-1 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1
176204 glr-1 Glutamate receptor 1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
176441 vglu-2 Major facilitator superfamily (MFS) profile domain-containing protein
176442 vglu-3 putative vesicular glutamate transporter vglu-3
177882 glt-3 Putative sodium-dependent excitatory amino acid transporter glt-3
180783 apl-1 Amyloid-beta-like protein
Displaying all 10 entries
Gene ID Gene Symbol Description Source
851013 ACO1 aconitate hydratase ACO1
851620 TPI1 triose-phosphate isomerase TPI1
853173 MTM1 Mtm1p
853770 BUD2 GTPase-activating protein BUD2
853792 OSI1 Osi1p
854943 NTE1 lysophospholipase
855392 FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase
855897 HRR25 serine/threonine protein kinase HRR25
856294 RHO1 Rho family GTPase RHO1
856422 RPN1 proteasome regulatory particle base subunit RPN1

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