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Standards Ontologies Notations
Parkinson's disease

Summary
Synonym
  • Parkinson disease
  • paralysis agitans
Definition
A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions.
Super Class
synucleinopathy
External Links
Disease Ontology
DOID:14330
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 91 - 100 of 180 in total
Gene ID Gene Symbol Description Source
5176 SERPINF1 serpin family F member 1
5230 PGK1 phosphoglycerate kinase 1
5232 PGK2 phosphoglycerate kinase 2
5562 PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2
5601 MAPK9 mitogen-activated protein kinase 9
5606 MAP2K3 mitogen-activated protein kinase kinase 3
5608 MAP2K6 mitogen-activated protein kinase kinase 6
5610 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2
5653 KLK6 kallikrein related peptidase 6
Displaying entries 1 - 10 of 146 in total
Gene ID Gene Symbol Description Source
11350 Abl1 c-abl oncogene 1, non-receptor tyrosine kinase
11423 Ache acetylcholinesterase
11529 Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
11607 Agtr1a angiotensin II receptor, type 1a
11608 Agtr1b angiotensin II receptor, type 1b
11651 Akt1 thymoma viral proto-oncogene 1
11652 Akt2 thymoma viral proto-oncogene 2
11747 Anxa5 annexin A5
12064 Bdnf brain derived neurotrophic factor
12317 Calr calreticulin
Displaying entries 1 - 10 of 82 in total
Gene ID Gene Symbol Description Source
24153 A2m alpha-2-macroglobulin
24180 Agtr1a angiotensin II receptor, type 1a
24185 Akt1 AKT serine/threonine kinase 1
24225 Bdnf brain-derived neurotrophic factor
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24318 Drd2 dopamine receptor D2
24335 Epo erythropoietin
24473 Htr1a 5-hydroxytryptamine receptor 1A
24483 Igf2 insulin-like growth factor 2
24596 Ngfr nerve growth factor receptor
Displaying entries 21 - 25 of 25 in total
Gene ID Gene Symbol Description Source
42803 Hmgcr HMG Coenzyme A reductase
42918 nAChRalpha1 nicotinic Acetylcholine Receptor alpha1
42920 nAChRbeta2 nicotinic Acetylcholine Receptor beta2
43565 Axn Axin
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 9 entries
Gene ID Gene Symbol Description Source
114549 ache acetylcholinesterase (Yt blood group)
436629 nus1 NUS1 dehydrodolichyl diphosphate synthase subunit
437021 tspan36 tetraspanin 36
494492 slc17a6a solute carrier family 17 member 6a
560788 parp1 poly (ADP-ribose) polymerase 1
563467 slc17a8 solute carrier family 17 member 8
768121 foxo1a forkhead box O1 a
100004455 epoa erythropoietin a
100149756 slc17a6b solute carrier family 17 member 6b
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
398763 agtr1.L angiotensin II receptor type 1 L homeolog Xenopus laevis (African clawed frog)
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
780064 slc17a7 solute carrier family 17 (vesicular glutamate transporter), member 7 Xenopus tropicalis (tropical clawed frog)
108705891 drd5.S dopamine receptor D5 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 26 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
173574 gba-1 Putative glucosylceramidase 1
174274 ptc-1 Protein patched homolog 1;SSD domain-containing protein
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175076 ace-3 Carboxylic ester hydrolase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176291 eat-4 Major facilitator superfamily (MFS) profile domain-containing protein;putative vesicular glutamate transporter eat-4
Displaying entries 11 - 19 of 19 in total
Gene ID Gene Symbol Description Source
853313 PBS2 mitogen-activated protein kinase kinase PBS2
853734 RRN3 rDNA-binding RNA polymerase I transcriptional factor
854276 INP53 phosphatidylinositol-3-/phosphoinositide 5-phosphatase INP53
854713 PRK1 serine/threonine protein kinase PRK1
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
854942 OGG1 8-oxoguanine glycosylase OGG1
855552 PSD1 phosphatidylserine decarboxylase 1
855711 ARK1 serine/threonine protein kinase ARK1
855999 SYH1 Syh1p
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024