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Standards Ontologies Notations
cancer

Summary
Synonym
  • malignant neoplasm
  • malignant tumor
  • primary cancer
Definition
A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
Super Class
disease of cellular proliferation
Disease Ontology
DOID:162
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 165 in total
Gene ID Gene Symbol Description Source
207 AKT1 AKT serine/threonine kinase 1
208 AKT2 AKT serine/threonine kinase 2
238 ALK ALK receptor tyrosine kinase
472 ATM ATM serine/threonine kinase
667 DST dystonin
675 BRCA2 BRCA2 DNA repair associated
963 CD53 CD53 molecule
1040 CDS1 CDP-diacylglycerol synthase 1
1436 CSF1R colony stimulating factor 1 receptor
1499 CTNNB1 catenin beta 1
Displaying entries 11 - 20 of 108 in total
Gene ID Gene Symbol Description Source
13388 Dll1 delta like canonical Notch ligand 1
13518 Dst dystonin
13619 Phc1 polyhomeotic 1
14254 Flt1 FMS-like tyrosine kinase 1
14255 Flt3 FMS-like tyrosine kinase 3
14257 Flt4 FMS-like tyrosine kinase 4
14567 Gdi1 GDP dissociation inhibitor 1
14897 Trip12 thyroid hormone receptor interactor 12
15516 Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1
15519 Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1
Displaying entries 1 - 10 of 36 in total
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24251 Cd53 Cd53 molecule
24479 Idh1 isocitrate dehydrogenase (NADP(+)) 1
24511 Itgb1 integrin subunit beta 1
24577 Myc MYC proto-oncogene, bHLH transcription factor
24644 Pgk1 phosphoglycerate kinase 1
24668 Ppp1ca protein phosphatase 1 catalytic subunit alpha
24669 Ppp1cc protein phosphatase 1 catalytic subunit gamma
24716 Ret ret proto-oncogene
24787 Sod2 superoxide dismutase 2
Displaying entries 1 - 10 of 13 in total
Gene ID Gene Symbol Description Source
31181 ph-p polyhomeotic proximal
31293 N Notch
32275 mew multiple edematous wings
33461 Pgk Phosphoglycerate kinase
36382 Sin3A Sin3A
36542 shot short stop
37386 shg shotgun
42313 Delta delta
43565 Axn Axin
43582 Tpi Triose phosphate isomerase
Displaying entries 1 - 10 of 13 in total
Gene ID Gene Symbol Description Source
30120 dlc deltaC
30141 dlb deltaB
30512 ret ret proto-oncogene receptor tyrosine kinase
30686 myca MYC proto-oncogene, bHLH transcription factor a
30718 notch1a notch receptor 1a
192309 tpi1a triosephosphate isomerase 1a
386856 pdgfra platelet-derived growth factor receptor, alpha polypeptide
393141 mycb MYC proto-oncogene, bHLH transcription factor b
431733 tspan9b tetraspanin 9b
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying all 4 entries
Gene ID Gene Symbol Description Source Organism
407879 ppp1cc protein phosphatase 1, catalytic subunit, gamma isozyme Xenopus tropicalis (tropical clawed frog)
496958 ppp1cb protein phosphatase 1, catalytic subunit, beta isozyme Xenopus tropicalis (tropical clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
100038162 tpi1 triosephosphate isomerase 1 Xenopus tropicalis (tropical clawed frog)
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
171965 pgk-1 putative phosphoglycerate kinase
175182 ver-1 Protein ver-1
175504 pat-3 Integrin beta pat-3
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176296 ina-1 Integrin alpha ina-1
177890 tsp-12 Tetraspanin-12
178759 apx-1 Anterior pharynx in excess protein 1;Delta-like protein;EGF-like domain-containing protein
179054 scd-2 ALK tyrosine kinase receptor homolog scd-2
181289 ver-3 Tyrosine-protein kinase receptor ver-3
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
850370 PGK1 phosphoglycerate kinase
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851620 TPI1 triose-phosphate isomerase TPI1
852261 RFT1 glycolipid translocation protein
852317 CDS1 phosphatidate cytidylyltransferase
853603 IML1 GTPase-activating protein IML1
853806 MPE1 cleavage polyadenylation factor subunit MPE1
853830 UGP1 UTP glucose-1-phosphate uridylyltransferase
854158 SIN3 transcriptional regulator SIN3
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024