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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
multiple sclerosis
Summary
- Synonym
-
- Generalized multiple sclerosis
- insular sclerosis
- Definition
- A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
- Super Class
- autoimmune disease of central nervous system demyelinating disease
External Links
- Disease Ontology
- DOID:2377
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 2 | A2M | alpha-2-macroglobulin | |
| 43 | ACHE | acetylcholinesterase (Yt blood group) | |
| 176 | ACAN | aggrecan | |
| 177 | AGER | advanced glycosylation end-product specific receptor | |
| 182 | JAG1 | jagged canonical Notch ligand 1 | |
| 183 | AGT | angiotensinogen | |
| 335 | APOA1 | apolipoprotein A1 | |
| 344 | APOC2 | apolipoprotein C2 | |
| 355 | FAS | Fas cell surface death receptor | |
| 356 | FASLG | Fas ligand |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 17441 | Mog | myelin oligodendrocyte glycoprotein | |
| 18039 | Nefl | neurofilament, light polypeptide | |
| 18053 | Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | |
| 18132 | Notch4 | notch 4 | |
| 18173 | Slc11a1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | |
| 18566 | Pdcd1 | programmed cell death 1 | |
| 18646 | Prf1 | perforin 1 (pore forming protein) | |
| 19264 | Ptprc | protein tyrosine phosphatase receptor type C | |
| 19294 | Nectin2 | nectin cell adhesion molecule 2 | |
| 20290 | Ccl1 | C-C motif chemokine ligand 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25084 | Il4r | interleukin 4 receptor | |
| 25145 | Cd24 | CD24 molecule | |
| 25307 | Cst3 | cystatin C | |
| 25353 | Spp1 | secreted phosphoprotein 1 | |
| 25385 | Faslg | Fas ligand | |
| 25625 | Tnfrsf1a | TNF receptor superfamily member 1A | |
| 25660 | Cd28 | Cd28 molecule | |
| 25704 | Il2ra | interleukin 2 receptor subunit alpha | |
| 25712 | Ifng | interferon gamma | |
| 29143 | Grn | granulin precursor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 32158 | cac | cacophony | |
| 36585 | beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A | |
| 39443 | Ptp69D | Protein tyrosine phosphatase 69D | |
| 39984 | Grd | Glycine receptor | |
| 41625 | Ace | Acetylcholine esterase | |
| 41840 | Hsc70-4 | Heat shock protein 70 cognate 4 | |
| 42490 | Mvl | Malvolio | |
| 43222 | Tl | Toll | |
| 43275 | Ser | Serrate | |
| 43425 | beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 114549 | ache | acetylcholinesterase (Yt blood group) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 393912 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 555941 | cacna1ba | calcium channel, voltage-dependent, N type, alpha 1B subunit, a | |
| 724080 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | |
| 100006041 | rhoab | ras homolog gene family, member Ab |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 446703 | b4galt5.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog | Xenopus laevis (African clawed frog) | |
| 548965 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | Xenopus tropicalis (tropical clawed frog) | |
| 549139 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | Xenopus tropicalis (tropical clawed frog) | |
| 779435 | b4galt6.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog | Xenopus laevis (African clawed frog) | |
| 108695277 | b4galt6.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog | Xenopus laevis (African clawed frog) | |
| 108702589 | b4galt5.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180638 | wrt-6 | Warthog protein 6 N-product | |
| 180931 | cpr-6 | Cathepsin B-like cysteine proteinase 6 | |
| 180939 | smf-1 | NRAMP-like transporter smf-1 | |
| 181706 | ace-1 | Acetylcholinesterase 1 | |
| 190602 | drag-1 | Repulsive guidance molecule B homolog drag-1 | |
| 190668 | bre-4 | Beta-1,4-N-acetylgalactosaminyltransferase bre-4 | |
| 191707 | mgl-1 | G-protein coupled receptors family 3 profile domain-containing protein;putative metabotropic glutamate receptor mgl-1 | |
| 191766 | smf-2 | NRAMP-like transporter smf-2 | |
| 3565419 | clr-1 | Receptor-type tyrosine-protein phosphatase;protein-tyrosine-phosphatase |
