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glioblastoma
Summary
- Synonym
-
- GBM
- adult glioblastoma multiforme
- glioblastoma multiforme
- grade IV adult Astrocytic tumor
- primary glioblastoma multiforme
- spongioblastoma multiforme
- Definition
- A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
- Super Class
- malignant astrocytoma
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 2146 | EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | |
| 2323 | FLT3LG | fms related receptor tyrosine kinase 3 ligand | |
| 3265 | HRAS | HRas proto-oncogene, GTPase | |
| 3371 | TNC | tenascin C | |
| 3417 | IDH1 | isocitrate dehydrogenase (NADP(+)) 1 | |
| 3603 | IL16 | interleukin 16 | |
| 3747 | KCNC2 | potassium voltage-gated channel subfamily C member 2 | |
| 3791 | KDR | kinase insert domain receptor | |
| 3845 | KRAS | KRAS proto-oncogene, GTPase | |
| 3897 | L1CAM | L1 cell adhesion molecule |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12258 | Serping1 | serine (or cysteine) peptidase inhibitor, clade G, member 1 | |
| 12654 | Chi3l1 | chitinase 3 like 1 | |
| 12876 | Cpe | carboxypeptidase E | |
| 12945 | Dmbt1 | deleted in malignant brain tumors 1 | |
| 13030 | Ctsb | cathepsin B | |
| 13036 | Ctsh | cathepsin H | |
| 13645 | Egf | epidermal growth factor | |
| 14056 | Ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | |
| 14256 | Flt3l | FMS-like tyrosine kinase 3 ligand | |
| 14726 | Pdpn | podoplanin |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24479 | Idh1 | isocitrate dehydrogenase (NADP(+)) 1 | |
| 24628 | Pdgfb | platelet derived growth factor subunit B | |
| 24629 | Pdgfrb | platelet derived growth factor receptor beta | |
| 24842 | Tp53 | tumor protein p53 | |
| 25313 | Egf | epidermal growth factor | |
| 25425 | Ctsh | cathepsin H | |
| 25589 | Kdr | kinase insert domain receptor | |
| 25669 | Cpe | carboxypeptidase E | |
| 29414 | Akt3 | AKT serine/threonine kinase 3 | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174437 | dep-1 | Receptor-type tyrosine-protein phosphatase dep-1 | |
| 175182 | ver-1 | Protein ver-1 | |
| 177078 | lad-2 | Ig-like domain-containing protein;Neuroglian | |
| 177940 | egl-21 | Carboxypeptidase E | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 179663 | enpp-1 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;NUC domain-containing protein | |
| 179665 | C27A7.3 | Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1;Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.3 | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180033 | cpr-3 | Cathepsin B-like cysteine proteinase 3 | |
| 180351 | W01F3.2 | Uncharacterized protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850391 | NPP1 | nucleotide diphosphatase/phosphodiesterase NPP1 | |
| 850871 | IDP2 | isocitrate dehydrogenase (NADP(+)) IDP2 | |
| 851493 | IDP1 | isocitrate dehydrogenase (NADP(+)) IDP1 | |
| 851977 | CTS2 | putative chitinase | |
| 853313 | PBS2 | mitogen-activated protein kinase kinase PBS2 | |
| 855723 | IDP3 | isocitrate dehydrogenase (NADP(+)) IDP3 | |
| 856699 | NPP2 | nucleotide diphosphatase/phosphodiesterase NPP2 |
