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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
amyotrophic lateral sclerosis
Summary
- Synonym
-
- ALS
- Lou Gehrig's disease
- motor neuron disease, bulbar
- Definition
- A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.
- Super Class
- motor neuron disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5704 | PSMC4 | proteasome 26S subunit, ATPase 4 | |
| 5705 | PSMC5 | proteasome 26S subunit, ATPase 5 | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 | |
| 5803 | PTPRZ1 | protein tyrosine phosphatase receptor type Z1 | |
| 6506 | SLC1A2 | solute carrier family 1 member 2 | |
| 6647 | SOD1 | superoxide dismutase 1 | |
| 6649 | SOD3 | superoxide dismutase 3 | |
| 7019 | TFAM | transcription factor A, mitochondrial | |
| 7422 | VEGFA | vascular endothelial growth factor A | |
| 8878 | SQSTM1 | sequestosome 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11829 | Aqp4 | aquaporin 4 | |
| 12266 | C3 | complement component 3 | |
| 12273 | C5ar1 | complement component 5a receptor 1 | |
| 12371 | Casp9 | caspase 9 | |
| 13191 | Dctn1 | dynactin 1 | |
| 13483 | Dpp6 | dipeptidylpeptidase 6 | |
| 13856 | Epo | erythropoietin | |
| 14030 | Ewsr1 | Ewing sarcoma breakpoint region 1 | |
| 14573 | Gdnf | glial cell line derived neurotrophic factor | |
| 14718 | Got1 | glutamic-oxaloacetic transaminase 1, soluble |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24232 | C3 | complement C3 | |
| 24335 | Epo | erythropoietin | |
| 24401 | Got1 | glutamic-oxaloacetic transaminase 1 | |
| 24588 | Nefm | neurofilament medium chain | |
| 25293 | Aqp4 | aquaporin 4 | |
| 25352 | Sod3 | superoxide dismutase 3 | |
| 25453 | Gdnf | glial cell derived neurotrophic factor | |
| 25459 | Hmgb1 | high mobility group box 1 | |
| 25589 | Kdr | kinase insert domain receptor | |
| 25613 | Ptprz1 | protein tyrosine phosphatase, receptor type Z1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31248 | sgg | shaggy | |
| 36232 | Sod3 | Superoxide dismutase 3 | |
| 38657 | vn | vein | |
| 38895 | Sarm | Sterile alpha and Armadillo motif | |
| 42490 | Mvl | Malvolio | |
| 42549 | InR | Insulin-like receptor | |
| 43223 | Lerp | lysosomal enzyme receptor protein | |
| 43469 | Ptp99A | Protein tyrosine phosphatase 99A | |
| 44811 | E(bx) | Enhancer of bithorax |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 403143 | sarm1 | sterile alpha and TIR motif containing 1 | |
| 447803 | pon1 | paraoxonase 1 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 798441 | mstnb | myostatin b | |
| 100004455 | epoa | erythropoietin a |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 380341 | pon2.L | paraoxonase 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 432039 | pon2.S | paraoxonase 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 779087 | gdnf.L | glial cell derived neurotrophic factor L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180641 | glt-1 | Excitatory amino acid transporter | |
| 180939 | smf-1 | NRAMP-like transporter smf-1 | |
| 181723 | hda-4 | Histone deacetylase 4 | |
| 186632 | ver-4 | Tyrosine-protein kinase receptor ver-4 | |
| 187297 | poml-1 | PON (paraoxonase) and MEC-6 Like | |
| 187623 | glt-6 | Putative sodium-dependent excitatory amino acid transporter glt-6 | |
| 191766 | smf-2 | NRAMP-like transporter smf-2 |
