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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
systemic scleroderma
Summary
- Synonym
-
- Scleroderma
- Scleroderma syndrome
- progressive systemic sclerosis
- systemic sclerosis
- Definition
- A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
- Super Class
- scleroderma
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4312 | MMP1 | matrix metallopeptidase 1 | |
| 4314 | MMP3 | matrix metallopeptidase 3 | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 4582 | MUC1 | mucin 1, cell surface associated | |
| 4803 | NGF | nerve growth factor | |
| 4855 | NOTCH4 | notch receptor 4 | |
| 5054 | SERPINE1 | serpin family E member 1 | |
| 5175 | PECAM1 | platelet and endothelial cell adhesion molecule 1 | |
| 5345 | SERPINF2 | serpin family F member 2 | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 18613 | Pecam1 | platelet/endothelial cell adhesion molecule 1 | |
| 18816 | Serpinf2 | serine (or cysteine) peptidase inhibitor, clade F, member 2 | |
| 19225 | Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| 19662 | Rbp4 | retinol binding protein 4, plasma | |
| 20296 | Ccl2 | C-C motif chemokine ligand 2 | |
| 20363 | Selenop | selenoprotein P | |
| 21812 | Tgfbr1 | transforming growth factor, beta receptor I | |
| 22339 | Vegfa | vascular endothelial growth factor A | |
| 22371 | Vwf | Von Willebrand factor | |
| 50931 | Il27ra | interleukin 27 receptor, alpha |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24179 | Agt | angiotensinogen | |
| 24225 | Bdnf | brain-derived neurotrophic factor | |
| 24232 | C3 | complement C3 | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24446 | Hgf | hepatocyte growth factor | |
| 24484 | Igfbp3 | insulin-like growth factor binding protein 3 | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24854 | Clu | clusterin | |
| 24890 | Esr1 | estrogen receptor 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 36868 | Idgf6 | Imaginal disc growth factor 6 | |
| 37104 | Idgf5 | Imaginal disc growth factor 5 | |
| 42490 | Mvl | Malvolio |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 791973 | cxcr3.2 | chemokine (C-X-C motif) receptor 3, tandem duplicate 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180628 | cht-1 | putative endochitinase | |
| 180780 | acn-1 | Inactive angiotensin-converting enzyme-related protein | |
| 180939 | smf-1 | NRAMP-like transporter smf-1 | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 182513 | gpx-3 | Glutathione peroxidase 3 | |
| 186632 | ver-4 | Tyrosine-protein kinase receptor ver-4 | |
| 191766 | smf-2 | NRAMP-like transporter smf-2 |
