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Standards Ontologies Notations
diabetes mellitus

Summary
Synonym
  • diabetes
Definition
A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
Super Class
glucose metabolism disease
Disease Ontology
DOID:9351
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 84 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
338 APOB apolipoprotein B
344 APOC2 apolipoprotein C2
345 APOC3 apolipoprotein C3
348 APOE apolipoprotein E
350 APOH apolipoprotein H
358 AQP1 aquaporin 1 (Colton blood group)
361 AQP4 aquaporin 4
406 BMAL1 basic helix-loop-helix ARNT like 1
653 BMP5 bone morphogenetic protein 5
Displaying entries 61 - 70 of 72 in total
Gene ID Gene Symbol Description Source
23920 Insrr insulin receptor-related receptor
26357 Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group)
54485 Dll4 delta like canonical Notch ligand 4
56373 Cpb2 carboxypeptidase B2
68916 Cdkal1 CDK5 regulatory subunit associated protein 1-like 1
71665 Fuca1 fucosidase, alpha-L- 1, tissue
103988 Gck glucokinase
108155 Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
116914 Slc19a2 solute carrier family 19 (thiamine transporter), member 2
238055 Apob apolipoprotein B
Displaying entries 31 - 40 of 46 in total
Gene ID Gene Symbol Description Source
54225 Apob apolipoprotein B
59086 Tgfb1 transforming growth factor, beta 1
60663 Insrr insulin receptor-related receptor
81818 Vim vimentin
83502 Cdh1 cadherin 1
83535 Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11
84349 Cd40lg CD40 ligand
113936 Cpb2 carboxypeptidase B2
116510 Timp1 TIMP metallopeptidase inhibitor 1
116568 Ggt1 gamma-glutamyltransferase 1
Displaying entries 11 - 20 of 21 in total
Gene ID Gene Symbol Description Source
38372 promL prominin-like
39836 st scarlet
42313 Delta delta
42549 InR Insulin-like receptor
42679 wfs1 wolfram syndrome 1
42803 Hmgcr HMG Coenzyme A reductase
43191 Hex-t2 Hexokinase testis 2
43222 Tl Toll
47905 l(2)03659 lethal (2) 03659
117364 Hex-t1 Hexokinase testis 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
64274 csf1ra colony stimulating factor 1 receptor, a
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
322857 prom1a prominin 1a
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
559080 cftr CF transmembrane conductance regulator
Displaying all 8 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
553157 ogt O-linked N-acetylglucosamine (GlcNAc) transferase Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175807 ida-1 Receptor-type tyrosine-protein phosphatase-like ida-1
176000 ogt-1 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178748 zmp-3 Matrix metalloproteinase-C
179053 cpr-4 Cathepsin B-like cysteine proteinase 4
179197 cri-2 Putative metalloproteinase inhibitor tag-225
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850462 GIT1 Git1p
850614 HXK1 hexokinase 1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
852128 EMI2 putative glucokinase
852543 VVS1 Vvs1p
852639 HXK2 hexokinase 2
853978 NFT1 putative multidrug transporter NFT1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024