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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
diabetes mellitus
Summary
- Synonym
-
- diabetes
- Definition
- A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both.
- Super Class
- glucose metabolism disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1559 | CYP2C9 | cytochrome P450 family 2 subfamily C member 9 | |
| 1585 | CYP11B2 | cytochrome P450 family 11 subfamily B member 2 | |
| 1595 | CYP51A1 | cytochrome P450 family 51 subfamily A member 1 | |
| 1956 | EGFR | epidermal growth factor receptor | |
| 2152 | F3 | coagulation factor III, tissue factor | |
| 2155 | F7 | coagulation factor VII | |
| 2335 | FN1 | fibronectin 1 | |
| 2517 | FUCA1 | alpha-L-fucosidase 1 | |
| 2539 | G6PD | glucose-6-phosphate dehydrogenase | |
| 2571 | GAD1 | glutamate decarboxylase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 15439 | Hp | haptoglobin | |
| 15894 | Icam1 | intercellular adhesion molecule 1 | |
| 16001 | Igf1r | insulin-like growth factor I receptor | |
| 16153 | Il10 | interleukin 10 | |
| 16184 | Il2ra | interleukin 2 receptor, alpha chain | |
| 16333 | Ins1 | insulin I | |
| 16334 | Ins2 | insulin II | |
| 16337 | Insr | insulin receptor | |
| 16398 | Itga2 | integrin alpha 2 | |
| 16514 | Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 25675 | Hmgcr | 3-hydroxy-3-methylglutaryl-CoA reductase | |
| 25704 | Il2ra | interleukin 2 receptor subunit alpha | |
| 25718 | Igf1r | insulin-like growth factor 1 receptor | |
| 25747 | Ppara | peroxisome proliferator activated receptor alpha | |
| 26295 | Ogt | O-linked N-acetylglucosamine (GlcNAc) transferase | |
| 29199 | Hfe | homeostatic iron regulator | |
| 29260 | Tlr4 | toll-like receptor 4 | |
| 29436 | Tfpi | tissue factor pathway inhibitor | |
| 29535 | Pdx1 | pancreatic and duodenal homeobox 1 | |
| 29714 | Ptprn2 | protein tyrosine phosphatase, receptor type N2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31234 | Pdfr | Pigment-dispersing factor receptor | |
| 31271 | w | white | |
| 32974 | Zw | Zwischenferment | |
| 34091 | Spn28Dc | Serpin 28Dc | |
| 35259 | Lar | Leukocyte-antigen-related-like | |
| 35486 | sxc | super sex combs | |
| 36692 | scb | scab | |
| 37455 | Egfr | Epidermal growth factor receptor | |
| 37778 | gbb | glass bottom boat | |
| 38109 | Glut1 | Glucose transporter 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30262 | ins | preproinsulin | |
| 64274 | csf1ra | colony stimulating factor 1 receptor, a | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 322857 | prom1a | prominin 1a | |
| 337685 | ogt.1 | O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 | |
| 559080 | cftr | CF transmembrane conductance regulator |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 397750 | hmgcr.L | 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 398006 | insr.L | insulin receptor L homeolog | Xenopus laevis (African clawed frog) | |
| 398022 | igf1r.S | insulin like growth factor 1 receptor S homeolog | Xenopus laevis (African clawed frog) | |
| 553157 | ogt | O-linked N-acetylglucosamine (GlcNAc) transferase | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171619 | C53D5.5 | Gamma-glutamyltranspeptidase 1 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 174685 | ptp-3 | Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175807 | ida-1 | Receptor-type tyrosine-protein phosphatase-like ida-1 | |
| 176000 | ogt-1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase | |
| 178046 | gspd-1 | Glucose-6-phosphate 1-dehydrogenase | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179053 | cpr-4 | Cathepsin B-like cysteine proteinase 4 | |
| 179197 | cri-2 | Putative metalloproteinase inhibitor tag-225 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850317 | GLK1 | glucokinase | |
| 850369 | ADP1 | putative ATP-dependent permease ADP1 | |
| 850462 | GIT1 | Git1p | |
| 850614 | HXK1 | hexokinase 1 | |
| 851006 | ECM38 | gamma-glutamyltransferase | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 852128 | EMI2 | putative glucokinase | |
| 852543 | VVS1 | Vvs1p | |
| 852639 | HXK2 | hexokinase 2 | |
| 853978 | NFT1 | putative multidrug transporter NFT1 |
