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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 221 - 230 of 325 in total
Gene ID Gene Symbol Description Source
6352 CCL5 C-C motif chemokine ligand 5
6383 SDC2 syndecan 2
6390 SDHB succinate dehydrogenase complex iron sulfur subunit B
6402 SELL selectin L
6403 SELP selectin P
6445 SGCG sarcoglycan gamma
6462 SHBG sex hormone binding globulin
6513 SLC2A1 solute carrier family 2 member 1
6514 SLC2A2 solute carrier family 2 member 2
6515 SLC2A3 solute carrier family 2 member 3
Displaying entries 61 - 70 of 249 in total
Gene ID Gene Symbol Description Source
13982 Esr1 estrogen receptor 1 (alpha)
14061 F2 coagulation factor II
14066 F3 coagulation factor III
14068 F7 coagulation factor VII
14069 F8 coagulation factor VIII
14071 F9 coagulation factor IX
14103 Fasl Fas ligand
14118 Fbn1 fibrillin 1
14161 Fga fibrinogen alpha chain
14234 Foxc2 forkhead box C2
Displaying entries 1 - 10 of 166 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24182 Agtr2 angiotensin II receptor, type 2
24185 Akt1 AKT serine/threonine kinase 1
24192 Akr1b1 aldo-keto reductase family 1 member B1
24221 Avp arginine vasopressin
24225 Bdnf brain-derived neurotrophic factor
24241 Calca calcitonin-related polypeptide alpha
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24310 Ace angiotensin I converting enzyme
Displaying entries 1 - 10 of 80 in total
Gene ID Gene Symbol Description Source
31234 Pdfr Pigment-dispersing factor receptor
31248 sgg shaggy
31271 w white
31806 Ogg1 8-oxoguanine DNA glycosylase
31926 Idgf4 Imaginal disc growth factor 4
32442 Rab3-GEF Rab3 GDP-GTP exchange factor
32974 Zw Zwischenferment
33007 Dop2R Dopamine 2-like receptor
33496 lilli lilliputian
34091 Spn28Dc Serpin 28Dc
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
30173 nog3 noggin 3
30174 nog1 noggin 1
30262 ins preproinsulin
30667 mtnr1aa melatonin receptor 1A a
30668 mtnr1bb melatonin receptor 1Bb
30682 vegfaa vascular endothelial growth factor Aa
266751 adra2b adrenoceptor alpha 2B
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source Organism
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380341 pon2.L paraoxonase 2 L homeolog Xenopus laevis (African clawed frog)
394283 sdc2.S syndecan 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
Displaying entries 21 - 30 of 69 in total
Gene ID Gene Symbol Description Source
177372 cpi-1 Cystatin cpi-1
177557 klo-1 Glycoside hydrolase family 1 protein
177668 C49C8.5 Fibrinogen C-terminal domain-containing protein
177850 gon-1 A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein
177911 Y43C5A.2 Fibrinogen C-terminal domain-containing protein
177940 egl-21 Carboxypeptidase E
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
178215 pgp-1 Multidrug resistance protein pgp-1
178330 ugt-22 UDP-glucuronosyltransferase
178585 srp-1 Serpin domain-containing protein
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2645 GCK glucokinase
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024