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Standards Ontologies Notations
type 2 diabetes mellitus

Summary
Synonym
  • NIDDM
  • insulin resistance
  • non-insulin-dependent diabetes mellitus
  • type 2 diabetes
  • type II diabetes mellitus
Definition
A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Super Class
diabetes mellitus
Disease Ontology
DOID:9352
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 311 - 320 of 325 in total
Gene ID Gene Symbol Description Source
64805 P2RY12 purinergic receptor P2Y12
64919 BCL11B BCL11 transcription factor B
79068 FTO FTO alpha-ketoglutarate dependent dioxygenase
80070 ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20
80339 PNPLA3 patatin like phospholipase domain containing 3
116519 APOA5 apolipoprotein A5
130120 REG3G regenerating family member 3 gamma
133522 PPARGC1B PPARG coactivator 1 beta
145264 SERPINA12 serpin family A member 12
170302 ARX aristaless related homeobox
Displaying entries 151 - 160 of 249 in total
Gene ID Gene Symbol Description Source
19662 Rbp4 retinol binding protein 4, plasma
20266 Scn1b sodium channel, voltage-gated, type I, beta
20296 Ccl2 C-C motif chemokine ligand 2
20317 Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1
20344 Selp selectin, platelet
20378 Frzb frizzled-related protein
20411 Sorbs1 sorbin and SH3 domain containing 1
20415 Shbg sex hormone binding globulin
20525 Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1
20526 Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2
Displaying entries 1 - 10 of 166 in total
Gene ID Gene Symbol Description Source
24152 Asip agouti signaling protein
24179 Agt angiotensinogen
24182 Agtr2 angiotensin II receptor, type 2
24185 Akt1 AKT serine/threonine kinase 1
24192 Akr1b1 aldo-keto reductase family 1 member B1
24221 Avp arginine vasopressin
24225 Bdnf brain-derived neurotrophic factor
24241 Calca calcitonin-related polypeptide alpha
24296 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1
24310 Ace angiotensin I converting enzyme
Displaying entries 41 - 50 of 80 in total
Gene ID Gene Symbol Description Source
41549 Octbeta2R Octopamine beta2 receptor
41573 Ugt37A2 UDP-glycosyltransferase family 37 member A2
41574 Ugt37A3 UDP-glycosyltransferase family 37 member A3
41625 Ace Acetylcholine esterase
42514 Snmp1 Sensory neuron membrane protein 1
42518 Oga O-GlcNAcase
42538 Ugt49B2 UDP-glycosyltransferase family 49 member B2
42549 InR Insulin-like receptor
42620 PyK Pyruvate kinase
42652 Octbeta1R Octopamine beta1 receptor
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
30173 nog3 noggin 3
30174 nog1 noggin 1
30262 ins preproinsulin
30667 mtnr1aa melatonin receptor 1A a
30668 mtnr1bb melatonin receptor 1Bb
30682 vegfaa vascular endothelial growth factor Aa
266751 adra2b adrenoceptor alpha 2B
321664 aldob aldolase b, fructose-bisphosphate
337685 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
393807 ppp1r3cb protein phosphatase 1, regulatory subunit 3Cb
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source Organism
373759 cnr1.S cannabinoid receptor 1 (brain) S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
379783 akt2.L v-akt murine thymoma viral oncogene homolog 2 L homeolog Xenopus laevis (African clawed frog)
380341 pon2.L paraoxonase 2 L homeolog Xenopus laevis (African clawed frog)
394283 sdc2.S syndecan 2 S homeolog Xenopus laevis (African clawed frog)
397750 hmgcr.L 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Xenopus laevis (African clawed frog)
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
398006 insr.L insulin receptor L homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 69 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
171782 abt-2 ABC transporter domain-containing protein
171905 ace-2 Carboxylic ester hydrolase
171999 poml-2 Arylesterase
172085 ugt-26 UDP-glucuronosyltransferase
172509 gpdh-3 putative glycerol-3-phosphate dehydrogenase, mitochondrial
173297 F49B2.6 Aminopeptidase
174685 ptp-3 Protein-tyrosine-phosphatase;Tyrosine-protein phosphatase Lar-like;protein-tyrosine-phosphatase
175076 ace-3 Carboxylic ester hydrolase
175182 ver-1 Protein ver-1
Displaying entries 1 - 10 of 32 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850369 ADP1 putative ATP-dependent permease ADP1
850391 NPP1 nucleotide diphosphatase/phosphodiesterase NPP1
850614 HXK1 hexokinase 1
850645 BPT1 ATP-binding cassette bilirubin transporter BPT1
850678 YBT1 bile acid-transporting ATPase YBT1
850886 ATG26 sterol 3-beta-glucosyltransferase
850979 PIG1 protein phosphatase regulator PIG1
851006 ECM38 gamma-glutamyltransferase
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
The Human Phenotype Ontology
Displaying all 4 entries
HPO ID HPO Term
HP:0000855 Insulin resistance
HP:0005978 Type II diabetes mellitus
HP:0000006 Autosomal dominant inheritance
HP:0003584 Late onset
Displaying all 6 entries
Gene ID Gene Symbol Description
2645 GCK glucokinase
2820 GPD2 glycerol-3-phosphate dehydrogenase 2
3990 LIPC lipase C, hepatic type
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5506 PPP1R3A protein phosphatase 1 regulatory subunit 3A
6514 SLC2A2 solute carrier family 2 member 2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024