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Repository for lectin-assisted multimodality data
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MIRAGE
type 2 diabetes mellitus
Summary
- Synonym
-
- NIDDM
- insulin resistance
- non-insulin-dependent diabetes mellitus
- type 2 diabetes
- type II diabetes mellitus
- Definition
- A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
- Super Class
- diabetes mellitus
External Links
- Disease Ontology
- DOID:9352
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- MGI genotype (from TogoID)
-
- 5504442
- 3760281
- 3766122
- 3789135
- 3842791
- 3847120
- 4361710
- 4429442
- 5294956
- 5301577
- 5428893
- 5435319
- 5502687
- 3721145
- 5620891
- 5637560
- 5638149
- 5695740
- 5766495
- 5789257
- 5804115
- 5804125
- 6111393
- 6160731
- 7314952
- 7622052
- 3531404
- 2175101
- 2177705
- 2385750
- 2385751
- 2653988
- 2654708
- 3028851
- 3029380
- 3051529
- 3052685
- 3510669
- 3510670
- 2174965
- 3531409
- 3582680
- 3583344
- 3583687
- 3583763
- 3583951
- 3583952
- 3586490
- 3590085
- 3623394
- 3629188
- 3694548
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1056 | CEL | carboxyl ester lipase | |
| 1268 | CNR1 | cannabinoid receptor 1 | |
| 1363 | CPE | carboxypeptidase E | |
| 1543 | CYP1A1 | cytochrome P450 family 1 subfamily A member 1 | |
| 1559 | CYP2C9 | cytochrome P450 family 2 subfamily C member 9 | |
| 1585 | CYP11B2 | cytochrome P450 family 11 subfamily B member 2 | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 1803 | DPP4 | dipeptidyl peptidase 4 | |
| 1813 | DRD2 | dopamine receptor D2 | |
| 2099 | ESR1 | estrogen receptor 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 20614 | Snap25 | synaptosomal-associated protein 25 | |
| 50518 | a | nonagouti | |
| 53412 | Ppp1r3c | protein phosphatase 1, regulatory subunit 3C | |
| 68916 | Cdkal1 | CDK5 regulatory subunit associated protein 1-like 1 | |
| 103988 | Gck | glucokinase | |
| 140491 | Ppp1r3a | protein phosphatase 1, regulatory subunit 3A | |
| 228355 | Madd | MAP-kinase activating death domain | |
| 266690 | Cyb5r4 | cytochrome b5 reductase 4 | |
| 384783 | Irs2 | insulin receptor substrate 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24185 | Akt1 | AKT serine/threonine kinase 1 | |
| 24385 | Gck | glucokinase | |
| 24536 | Lepr | leptin receptor | |
| 24617 | Serpine1 | serpin family E member 1 | |
| 24835 | Tnf | tumor necrosis factor | |
| 24889 | Cckar | cholecystokinin A receptor | |
| 25024 | Gipr | gastric inhibitory polypeptide receptor | |
| 25204 | Pcsk1 | proprotein convertase subtilisin/kexin type 1 | |
| 25467 | Irs1 | insulin receptor substrate 1 | |
| 25608 | Lep | leptin |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 176000 | ogt-1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase;protein O-GlcNAc transferase | |
| 177850 | gon-1 | A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein | |
| 266823 | parp-1 | Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 | |
| Q9Y4H2 | Insulin receptor substrate 2 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| O08590 | Amine oxidase [copper-containing] 3 | |
| P15127 | Insulin receptor | |
| P16599 | Tumor necrosis factor | |
| P20961 | Plasminogen activator inhibitor 1 | |
| P21451 | Endothelin receptor type B | |
| P28840 | Neuroendocrine convertase 1 | |
| P30551 | Cholecystokinin receptor type A | |
| P35570 | Insulin receptor substrate 1 | |
| P43219 | Gastric inhibitory polypeptide receptor | |
| P43428 | Glucose-6-phosphatase catalytic subunit 1 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P09208 | Insulin-like receptor | |
| Q9VQI9 | AF4/FMR2 family member lilli |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q19791 | A disintegrin and metalloproteinase with thrombospondin motifs gon-1 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P38703 | Ceramide synthase LAG1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000855 | Insulin resistance |
| HP:0005978 | Type II diabetes mellitus |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0003584 | Late onset |
| Gene ID | Gene Symbol | Description |
|---|---|---|
| 2645 | GCK | glucokinase |
| 2820 | GPD2 | glycerol-3-phosphate dehydrogenase 2 |
| 3990 | LIPC | lipase C, hepatic type |
| 5167 | ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| 5506 | PPP1R3A | protein phosphatase 1 regulatory subunit 3A |
| 6514 | SLC2A2 | solute carrier family 2 member 2 |
