heroin dependence

Summary
Definition
An opiate dependence that involves the continued use of heroin despite problems related to use of the substance.
Super Class
opiate dependence
Disease Ontology
DOID:9976
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 1 - 10 of 35 in total
Gene ID Gene Symbol Description Source
18 ABAT 4-aminobutyrate aminotransferase
43 ACHE acetylcholinesterase (Yt blood group)
148 ADRA1A adrenoceptor alpha 1A
217 ALDH2 aldehyde dehydrogenase 2 family member
355 FAS Fas cell surface death receptor
590 BCHE butyrylcholinesterase
627 BDNF brain derived neurotrophic factor
1129 CHRM2 cholinergic receptor muscarinic 2
1312 COMT catechol-O-methyltransferase
1385 CREB1 cAMP responsive element binding protein 1
Displaying entries 31 - 34 of 34 in total
Gene ID Gene Symbol Description Source
54393 Gabbr1 gamma-aminobutyric acid type B receptor subunit 1
108068 Grm2 glutamate receptor, metabotropic 2
243764 Chrm2 cholinergic receptor, muscarinic 2, cardiac
244859 Ankk1 ankyrin repeat and kinase domain containing 1
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
25601 Oprm1 opioid receptor, mu 1
29237 Penk proenkephalin
29238 Drd3 dopamine receptor D3
29335 Oprk1 opioid receptor, kappa 1
29412 Adra1a adrenoceptor alpha 1A
29539 Aldh2 aldehyde dehydrogenase 2 family member
29709 Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2
50592 Gria1 glutamate ionotropic receptor AMPA type subunit 1
79246 Htr3a 5-hydroxytryptamine receptor 3A
81645 Chrm2 cholinergic receptor, muscarinic 2
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
32554 Lcch3 Ligand-gated chloride channel homolog 3
33007 Dop2R Dopamine 2-like receptor
36428 Mdr49 Multi drug resistance 49
36849 DAT Dopamine transporter
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
38726 Mdr65 Multi drug resistance 65
38742 GluRIA Glutamate receptor IA
41625 Ace Acetylcholine esterase
41726 Dop1R1 Dopamine 1-like receptor 1
43484 Dop1R2 Dopamine 1-like receptor 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
58133 ngfb nerve growth factor b (beta polypeptide)
114549 ache acetylcholinesterase (Yt blood group)
561372 comta catechol-O-methyltransferase a
565370 comtb catechol-O-methyltransferase b
Displaying all 4 entries
Gene ID Gene Symbol Description Source Organism
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
100127346 grin2a.L glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
171905 ace-2 Carboxylic ester hydrolase
175076 ace-3 Carboxylic ester hydrolase
175999 glr-2 Glutamate receptor 2
176204 glr-1 Glutamate receptor 1
176304 dat-1 Sodium-dependent dopamine transporter
176691 gab-1 Gamma-aminobutyric acid receptor subunit beta
178215 pgp-1 Multidrug resistance protein pgp-1
179347 dop-2 Dopamine receptor 2
179962 gar-3 Muscarinic acetylcholine receptor gar-3
180714 dop-1 Dopamine receptor 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
853671 STE6 ATP-binding cassette a-factor transporter STE6

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