GlyCosmos Portal

Rattus norvegicus (Norway rat)

Summary

Taxonomy ID: 10116
PubChem Taxonomy: 10116

Genes (449) Glycans (773) Glycoproteins (2935) Lectins (166) Pathways (1070)

Displaying entries **701 - 725** of **1070** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	GlyTouCan ID
SUMOylation of ubiquitinylation proteins	Aladin WD repeat nucleoporin E3 SUMO-protein ligase PIAS2 E3 ubiquitin-protein ligase Mdm2 LOC683983 protein Nuclear envelope pore membrane protein POM 121 Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup54 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore complex protein Nup98-Nup96 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin 133 Nucleoporin 160 Nucleoporin 205 Nucleoporin 214 Nucleoporin 37 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin p58/p45 Nucleoprotein TPR PML nuclear body scaffold Protein SEC13 homolog Protein inhibitor of activated STAT, 1 Protein inhibitor of activated STAT, 4 RAN binding protein 2 RING-type E3 ubiquitin transferase SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 mRNA export factor von Hippel-Lindau disease tumor suppressor	A0A0G2K3M4 A0A8I5YC36 A0A8I5YCH6 A0A8I5ZJ67 A0A8I6AC37 A0A8I6AJT7 A0A8I6G5V3 B0BNB5 B5DFF9 B5DFI5 D3Z8B2 D3ZBL6 D3ZHV0 D4ACK1 F1LRC6 F1MA98 O08587 O08658 P11654 P17955 P37199 P49791 P49793 P52590 P52591 P63281 P70581 P70582 Q3SWS8 Q4QQS8 Q5I0H3 Q5XFW8 Q64259 Q66HC5 Q68FY1 Q6AXN4 Q6AZ28	Aaas Gp210 LOC683983 Mdm2 Miz1 Mrnp41 Ndc1 Npap60 Nup107 Nup121 Nup133 Nup153 Nup155 Nup160 Nup188 Nup205 Nup210 Nup214 Nup35 Nup37 Nup42 Nup43 Nup50 Nup53 Nup54 Nup58 Nup62 Nup84 Nup85 Nup88 Nup93 Nup98 Nupl1 Nupl2 Pcnt1 Pias1 Pias2 Pias4 Piasx Pml Pom121 Pom210 Rae1 Ranbp2 Sec13 Sec13l1 Sumo1 Tmem48 Tpr Trim27 Ubce9 Ube2i Vhl
Nuclear Pore Complex (NPC) Disassembly	Aladin WD repeat nucleoporin Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 G2/mitotic-specific cyclin-B2 LOC683983 protein Nuclear envelope pore membrane protein POM 121 Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup54 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore complex protein Nup98-Nup96 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin 133 Nucleoporin 160 Nucleoporin 205 Nucleoporin 214 Nucleoporin 37 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin p58/p45 Nucleoprotein TPR Protein SEC13 homolog RAN binding protein 2 mRNA export factor	A0A0G2K3M4 A0A8I5YC36 A0A8I5YCH6 A0A8I5ZJ67 A0A8I6A3R0 B0BNB5 D3Z8B2 D3ZBL6 D3ZHV0 D4ACK1 F1LRC6 F1MA98 O08587 O08658 P11654 P17955 P30277 P37199 P39951 P49791 P49793 P52590 P52591 P70581 P70582 Q3SWS8 Q4QQS8 Q5M857 Q5XFW8 Q66HC5 Q68FY1 Q6AXN4	Aaas Ccnb1 Ccnb2 Ccnb2-ps2 Cdc2 Cdc2a Cdk1 Cdkn1 Gp210 LOC683983 Mrnp41 Ndc1 Npap60 Nup107 Nup121 Nup133 Nup153 Nup155 Nup160 Nup188 Nup205 Nup210 Nup214 Nup35 Nup37 Nup42 Nup43 Nup50 Nup53 Nup54 Nup58 Nup62 Nup84 Nup85 Nup88 Nup93 Nup98 Nupl1 Nupl2 Pcnt1 Pom121 Pom210 Rae1 Ranbp2 Sec13 Sec13l1 Tmem48 Tpr
snRNP Assembly	Aladin WD repeat nucleoporin GEM (Nuclear organelle) associated protein 8 Gem (nuclear organelle) associated protein 4 Gem (nuclear organelle) associated protein 5 Gem (nuclear organelle) associated protein 6 Gem (nuclear organelle) associated protein 7-like 1 Gem (nuclear organelle) associated protein 7 Gem-associated protein 2 LOC683983 protein Methylosome protein WDR77 Methylosome subunit pICln Nuclear envelope pore membrane protein POM 121 Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup54 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore complex protein Nup98-Nup96 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin 133 Nucleoporin 160 Nucleoporin 205 Nucleoporin 214 Nucleoporin 37 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin p58/p45 Nucleoprotein TPR Protein SEC13 homolog Protein arginine N-methyltransferase 5 RAN binding protein 2 RNA helicase Sm protein F Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated protein B Snurportin-1 Survival motor neuron protein Trimethylguanosine synthase mRNA export factor	A0A0G2K3M4 A0A8I5YC36 A0A8I5YCH6 A0A8I5ZJ67 A0A8I5ZR44 A0A8I6AI37 B0BNB5 B5DEP7 D3Z8B2 D3ZBL6 D3ZGD0 D3ZHV0 D3ZSP1 D4A0E8 D4AAT4 D4ACK1 F1LRC6 F1LWL5 F1M629 F1MA98 F1MAM8 G3V972 M0R5G2 O08587 O08658 O35876 P11654 P17136 P17955 P37199 P49791 P49793 P52590 P52591 P70581 P70582 P85107 Q04753 Q3SWS8 Q4QQS8 Q4QR85 Q5XFW8 Q66HC5 Q68FP5 Q68FY1 Q6AXN4 Q6AY77 Q9QZP1	Aaas Clns1a Ddx20 Fam51a1 Gemin2 Gemin4 Gemin5 Gemin6 Gemin7 Gemin7l1 Gemin8 Gp210 Icln LOC683983 LOC687679 Mep50 Mrnp41 Ncoa6ip Ndc1 Npap60 Nup107 Nup121 Nup133 Nup153 Nup155 Nup160 Nup188 Nup205 Nup210 Nup214 Nup35 Nup37 Nup42 Nup43 Nup50 Nup53 Nup54 Nup58 Nup62 Nup84 Nup85 Nup88 Nup93 Nup98 Nupl1 Nupl2 Pcnt1 Pimt Pom121 Pom210 Prmt5 Rae1 Ranbp2 Rcl1 Rnut1 SNRPD2 SNRPD3 Sec13 Sec13l1 Sip1 Smn Smn1 Snrpb Snrpd2 Snrpd3 Snrpe Snrpepl2 Snrpf Snrpg Snrpgl1 Snupn Tgs1 Tmem48 Tpr Wdr77
SUMOylation of DNA replication proteins	Aladin WD repeat nucleoporin Aurora kinase B Baculoviral IAP repeat-containing protein 5 Borealin DNA topoisomerase 1 DNA topoisomerase 2-alpha DNA topoisomerase 2 E3 SUMO-protein ligase PIAS3 Inner centromere protein LOC683983 protein Nuclear envelope pore membrane protein POM 121 Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup54 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore complex protein Nup98-Nup96 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin 133 Nucleoporin 160 Nucleoporin 205 Nucleoporin 214 Nucleoporin 37 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin p58/p45 Nucleoprotein TPR Proliferating cell nuclear antigen Protein inhibitor of activated STAT, 4 RAN GTPase activating protein 1 RAN binding protein 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 mRNA export factor	A0A0G2K3M4 A0A0G2K5R3 A0A8I5Y7L4 A0A8I5YC36 A0A8I5YCH6 A0A8I5ZJ67 A0A8I5ZZ56 B0BNB5 B5DFF9 D3Z8B2 D3ZBL6 D3ZHV0 D4ACK1 F1LRC6 F1MA98 O08587 O08658 O55099 O70260 P04961 P11654 P17955 P37199 P41516 P49791 P49793 P52590 P52591 P61959 P63281 P70581 P70582 Q3SWS8 Q4QQS8 Q5I0H3 Q5XIF4 Q66HC5 Q68FY1 Q6AXN4 Q6AXW0 Q9JHY7 Q9WUL0	Aaas Aik2 Aim1 Airk2 Ark2 Aurkb Birc5 Cdca8 Gp210 Incenp LOC683983 Mrnp41 Ndc1 Npap60 Nup107 Nup121 Nup133 Nup153 Nup155 Nup160 Nup188 Nup205 Nup210 Nup214 Nup35 Nup37 Nup42 Nup43 Nup50 Nup53 Nup54 Nup58 Nup62 Nup84 Nup85 Nup88 Nup93 Nup98 Nupl1 Nupl2 Pcna Pcnt1 Pias3 Pias4 Pom121 Pom210 Rae1 Ranbp2 Rangap1 Smt3a Smt3h2 Stk1 Stk12 Stk5 Sumo1 Sumo2 Sumo3 Tmem48 Top-2 Top1 Top2 Top2a Top2b Tpr Ubce9 Ube2i
Glycosphingolipid biosynthesis	2-hydroxyacylsphingosine 1-beta-galactosyltransferase Alpha-2,8-sialyltransferase 8E Beta-1,3-galactosyltransferase 4 Beta-1,4 N-acetylgalactosaminyltransferase 1 Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 Ceramide glucosyltransferase Ceramide kinase Galactose-3-O-sulfotransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 UDP-GalNAc	A0A0G2K3K5 D3Z9Y3 D3ZCT9 M0R3S4 O88178 O88419 Q02734 Q09426 Q10468 Q10980 Q10984 Q11205 Q68G12 Q6AY39 Q6ZXC8 Q6ZXY9 Q99NB2 Q9JI93 Q9R0E0	A4galt B3galnt1 B3galt3 B3galt4 B3gnt5 B4galnt1 B4galt5 B4galt6 Cerk Cgt Fta Ftb Fut1 Fut2 Gal3st1 Galgt Galgt1 Sec1 Siat4b Siat5 Siat6 Siat8e Siat9 St3gal2 St3gal3 St3gal5 St6galnac5 St6galnac6 St8sia5 St8siav Ugcg Ugt4 Ugt8
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A Alpha-2,8-sialyltransferase 8B Beta-1,4-galactosyltransferase 3 Beta-1,4-galactosyltransferase 4 Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 MGAT4 family, member C ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	A0A0G2K3K5 B2GV39 D3ZEV3 D4A2A5 G3V8D0 O88419 P13721 P61131 Q07977 Q08834 Q5M854 Q66HH1 Q6P768	B4galt2 B4galt3 B4galt4 B4galt5 B4galt6 Mgat4a Mgat4b Mgat4c Mgat5 Siat1 Siat4c Siat8b St3gal4 St6gal1 St8sia2 St8sia3 Stx	G81533KY
Keratan sulfate biosynthesis	Aggrecan core protein Beta-1,4-galactosyltransferase 3 Beta-1,4-galactosyltransferase 4 Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 Carbohydrate sulfotransferase 1 Carbohydrate sulfotransferase 5 Fibromodulin Hexosyltransferase Hexosyltransferase Hexosyltransferase Keratocan Lumican Osteomodulin Prolargin Solute carrier family 35 member D2 Sulfotransferase Type 2 lactosamine alpha-2,3-sialyltransferase UDP-GlcNAc	A0A0G2K3K5 A0A1W2Q5Z7 D3ZEF9 D3ZVD7 D3ZX31 D4A1T9 D4A2A5 D4A3H6 D4A9P8 M0R868 O88419 P07897 P50609 P51886 P61131 P61943 Q02734 Q11205 Q5RJQ0 Q66H69 Q66HH1 Q6P768 Q9EQP5 Q9Z1S7	Acan Agc Agc1 B3gnt2 B3gnt3 B3gnt4 B3gnt7 B4galt2 B4galt3 B4galt4 B4galt5 B4galt6 Chst1 Chst2 Chst5 Fmod Kera Lcn Ldc Lum Omd Prelp Siat10 Siat4b Siat4c Siat5 Siat6 Slc35d2 St3gal1 St3gal2 St3gal3 St3gal4 St3gal6
MET activates RAP1 and RAC1	Adapter molecule crk Crk-like protein Dedicator of cytokinesis 7 GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rap-1A Ras-related protein Rap-1b	A0A0G2K3H2 D3ZAL7 F1M8L9 P17945 P62836 P62994 P97523 Q5U2U2 Q62636 Q63768 Q6RUV5	Ash Crk Crkl Crko Dock7 Gab1 Grb2 Hgf Krev1 Met Rac Rac1 Rap1a Rap1b Rapgef1
WNT ligand biogenesis and trafficking	Protein Wnt-4 Protein Wnt-5a Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein wntless homolog Sorting nexin-3 Transmembrane emp24 domain-containing protein 5 Vacuolar protein sorting-associated protein 26A Vacuolar protein sorting-associated protein 29 Vacuolar protein sorting-associated protein 35	A0A0G2K3B7 A0A0G2K6Q8 A0A8I6A874 A0A8I6AN69 B1WBR9 B2RZ78 D3ZF63 D3ZFS0 D3ZND6 D3ZRW5 D4A3K6 D4A3W9 D4A9D7 D4A9J2 F1M077 G3V819 G3V8A5 M0R9D3 Q5U211 Q6AXN3 Q6AY86 Q6P689 Q9QXQ5 Q9QXQ7	Gpr177 Snx3 Tmed5 Vps26 Vps26a Vps29 Vps35 Wls Wnt-4 Wnt-5a Wnt1 Wnt10a Wnt10b Wnt11 Wnt16 Wnt2b Wnt3 Wnt3a Wnt4 Wnt5a Wnt5b Wnt6 Wnt7a Wnt7b Wnt8a Wnt8b Wnt9a Wnt9b
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	A0A0G2K344 F1MAL5 P35570 Q63787 Q63788 Q9Z1L0	Irs-1 Irs1 Irs2 Pik3ca Pik3cb Pik3r1 Pik3r2
PI3K/AKT activation	Beta-nerve growth factor High affinity nerve growth factor receptor Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Transforming protein RhoA	A0A0G2K344 F1MAL5 P25427 P35570 P35739 P61589 Q63787 Q63788 Q9Z1L0	Arha Arha2 Irs-1 Irs1 Irs2 Ngf Ngfb Ntrk1 Pik3ca Pik3cb Pik3r1 Pik3r2 Rhoa Trk Trka
MET activates PI3K/AKT signaling	GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	A0A0G2K344 D3ZAL7 P17945 P62994 P97523 Q63787	Ash Gab1 Grb2 Hgf Met Pik3ca Pik3r1
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK and LTK ligand 1 ALK and LTK ligand 2 Insulin receptor substrate 1 Midkine Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Pleiotrophin SHC-transforming protein 1 Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK3 Tyrosine-protein kinase receptor Tyrosine-protein phosphatase non-receptor type 6	A0A0G2K344 B2RZ42 F1LRZ0 M0R9C8 P10686 P35570 P52631 P63090 P81718 Q5M824 Q63272 Q63787 Q63788 Q9R1S9 Q9Z1L0	Alk Alkal1 Alkal2 Fam150a Irs-1 Irs1 Jak3 LOC100910984 Mdk Pik3ca Pik3cb Pik3r1 Pik3r2 Plcg1 Ptn Ptph6 Ptpn6 Shc1 Stat3
Signaling by LTK	ALK and LTK ligand 1 ALK and LTK ligand 2 Activated CDC42 kinase 1 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A0G2K344 A0A8I6GCV6 B2RZ42 D4A3T0 M0R9C8 P35570 P62994 Q5M824 Q5U2X5 Q63787 Q63788 Q9Z1L0	Ack1 Alkal1 Alkal2 Ash Fam150a Grb2 Irs-1 Irs1 LOC100910984 Ltk Pik3ca Pik3cb Pik3r1 Pik3r2 Shc1 Sos1 Tnk2
PI-3K cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 17 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Klotho Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6B5D5 D3ZAL7 D4A244 F1LSQ8 P13109 P36364 P41499 P48807 P61149 P62994 P63076 P70492 Q04589 Q63787 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9 Q9Z2Y9	Ash FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf10 Fgf17 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr1 Flg Frs2 Gab1 Grb2 Kl Pik3ca Pik3r1 Ptpn11
PI-3K cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6B5D5 D3ZAL7 D4A244 F1LSG7 F1LSQ8 O54769 O88182 P13109 P36364 P41499 P48807 P61149 P62994 P63076 P70492 Q02195 Q63787 Q8R5L5 Q8R5L9 Q8VI79 Q8VI82 Q9EST9	Ash FGF22 FGF6 Fgf-1 Fgf-2 Fgf-5 Fgf-7 Fgf-9 Fgf1 Fgf10 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf22 Fgf23 Fgf3 Fgf4 Fgf5 Fgf5c Fgf5d Fgf6 Fgf7 Fgf7a Fgf7b Fgf8 Fgf9 Fgfa Fgfr2 Frs2 Gab1 Grb2 Kgf Pik3ca Pik3r1 Ptpn11
PI-3K cascade:FGFR4	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Klotho beta Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6B5D5 D3Z8T6 D3ZAL7 D4A244 F1LSQ8 O54769 O88182 P13109 P36364 P41499 P61149 P62994 P63076 Q498D6 Q63787 Q8R5L5 Q8VI81 Q8VI82 Q9EST9	Ash FGF15 FGF6 Fgf-1 Fgf-2 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf19 Fgf2 Fgf20 Fgf23 Fgf4 Fgf6 Fgf7a Fgf7b Fgf8 Fgf8a Fgf9 Fgfa Fgfr4 Frs2 Gab1 Grb2 Klb Pik3ca Pik3r1 Ptpn11
Costimulation by the CD28 family	B- and T-lymphocyte attenuator Growth factor receptor-bound protein 2 Inducible T-cell co-stimulator ligand Inducible T-cell costimulator Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform TNF receptor superfamily member 14 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	A0A0G2K344 A0A8I6ATG2 F1LVL2 P41499 P62994 P81718 Q63787 Q63788 Q63789 Q6PNM1 Q9R1T7	Ailim Ash Btla Grb2 Icos Icoslg Pik3ca Pik3r1 Pik3r2 Pik3r3 Ptph6 Ptpn11 Ptpn6 Tnfrsf14
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Amphiregulin Betacellulin Calmodulin-3 Caveolin-1 Caveolin-2 Estrogen receptor beta Estrogen receptor Focal adhesion kinase 1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Heat shock protein HSP 90-alpha Insulin-like growth factor 1 receptor Matrilysin Matrix metalloproteinase-9 Nitric oxide synthase 3 Palmitoyltransferase ZDHHC7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Protein arginine N-methyltransferase 1 Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase Receptor protein-tyrosine kinase SHC-transforming protein 1 Sphingosine kinase 1 Sphingosine-1-phosphate receptor 3 Striatin Stromelysin-1	A0A0G2K344 A0A8I6AQ55 F1M9D3 G3V6K6 O35346 P01134 P03957 P04897 P06211 P07522 P08753 P0DP31 P10824 P24062 P24338 P29348 P33436 P41350 P47196 P50280 P50282 P70483 P82995 Q06175 Q2IBC5 Q5M824 Q62600 Q62986 Q63009 Q63787 Q63788 Q63789 Q91V26 Q923G5 Q9WUD9 Q9Z0L5	Akt1 Areg Btc CaMIII Calm3 Cam3 Camc Cav Cav1 Cav2 Dtr Egf Egfr Erbeta Ereg Esr Esr1 Esr2 Estr Fak Fak1 Gnai-1 Gnai-2 Gnai-3 Gnai1 Gnai2 Gnai3 Gnat-3 Gnat3 Hbegf Hegfl Hrmt1l2 Hsp86 Hsp90aa1 Hspca Igf1r Mmp-7 Mmp2 Mmp3 Mmp7 Mmp9 Nos3 Nr3a1 Nr3a2 Pik3ca Pik3r1 Pik3r2 Pik3r3 Prmt1 Ptk2 S1pr3 Sdgf Serz Shc1 Sphk1 Src Strn Tgfa Zdhhc7
GAB1 signalosome	Amphiregulin Betacellulin GRB2-associated binding protein 1 Growth factor receptor-bound protein 2 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Pro-epidermal growth factor Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha Receptor protein-tyrosine kinase Tyrosine-protein kinase CSK Tyrosine-protein phosphatase non-receptor type 11	A0A0G2K344 A0A8I6AQ55 D3ZAL7 G3V6K6 P01134 P07522 P24338 P32577 P41499 P62994 Q06175 Q63787 Q66H76 Q9JM80 Q9WUD9 Q9Z0L5	Areg Ash Btc Cbp Csk Dtr Egf Egfr Ereg Gab1 Grb2 Hbegf Hegfl Pag Pag1 Pik3ca Pik3r1 Ptpn11 Pxn Sdgf Src Tgfa
Tie2 Signaling	Angiopoietin 4 Angiopoietin-1 Angiopoietin-2 Docking protein 2 GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 14 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 receptor protein-tyrosine kinase	A0A0G2K344 A0A8I5ZW61 A0A8I6ALT5 D3ZR43 D4A3T0 O35460 O35462 O88900 P08644 P20171 P41499 P62994 Q04970 Q5M824 Q63787 Q63788 Q9QZC5 Q9Z1L0	Agpt2 Angpt1 Angpt2 Angpt4 Ash Dok2 Grb14 Grb2 Grb7 Hras Hras1 Kras Kras2 Nras Pik3ca Pik3cb Pik3r1 Pik3r2 Ptpn11 Shc1 Sos1 Tek
GPVI-mediated activation cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 3-phosphoinositide-dependent protein kinase 1 C-type lectin domain family 1 member B Cell division control protein 42 homolog Glycoprotein VI High affinity immunoglobulin epsilon receptor subunit gamma Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide-3-kinase, regulatory subunit 6 Podoplanin Proto-oncogene tyrosine-protein kinase LCK Proto-oncogene vav Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoB Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5ZPB5 A0A8I6A1P8 A0A8I6G942 A0A8J8YIH6 D3ZFJ0 D3ZJD8 D3ZYG0 D4A4I3 M0R8A3 O55173 O70601 P20411 P24135 P41499 P54100 P61589 P62747 P81718 Q01621 Q07014 Q32PX6 Q62844 Q63787 Q63788 Q63789 Q64294 Q64725 Q6MG59 Q6RUV5 Q8CFN2 Q9Z1L0	Arha Arha2 Arhb Cdc42 Clec1b Fce1g Fcer1g Fyn G6b Gp6 Lat Lck Lcp2 Lyn Mpig6b Pdk1 Pdpk1 Pdpn Pik3ca Pik3cb Pik3cg Pik3r1 Pik3r2 Pik3r3 Pik3r5 Pik3r6 Plcg2 Ptph6 Ptpn11 Ptpn6 Rac Rac1 Rac2 Rhoa Rhob Rhog Syk Vav Vav1 Vav2 Vav3
CD28 dependent PI3K/Akt signaling	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 CD86 molecule Cd80 molecule Mitogen-activated protein kinase kinase kinase 14 Mitogen-activated protein kinase kinase kinase 8 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proline-rich protein 5 Proto-oncogene tyrosine-protein kinase LCK RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase RPTOR independent companion of MTOR, complex 2 Serine/threonine-protein kinase mTOR T-cell-specific surface glycoprotein CD28 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tribbles homolog 3 Tyrosine-protein kinase Fyn	A0A0G2K344 A0A8I5ZNG4 D3ZTD1 G3V671 O35531 O55173 P31042 P42346 P47196 P47197 Q01621 Q566R0 Q5FVG6 Q62844 Q63484 Q63562 Q63787 Q63788 Q63789 Q6AYF1 Q9WTQ6 Q9Z2K5	Akt1 Akt2 Akt3 Cd28 Cd80 Cd86 Frap1 Fyn Gbl Lck Lst8 Map3k14 Map3k8 Mapkap1 Mip1 Mlst8 Mtor Nipk Pdk1 Pdpk1 Pik3ca Pik3r1 Pik3r2 Pik3r3 Protor1 Prr5 Raft1 Rictor Sin1 Them4 Tpl2 Trib3
VEGFA-VEGFR2 Pathway	Abl interactor 1 Abl-interactor 2 Actin-binding protein WASF1 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 BRICK1 subunit of SCAR/WAVE actin nucleating complex Breast cancer anti-estrogen resistance protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein Cytoplasmic protein Cytoplasmic protein Engulfment and cell motility 1 Engulfment and cell motility 2 Focal adhesion kinase 1 Heat shock protein HSP 90-alpha Heat shock protein beta-1 Integrin beta-3 Integrin subunit alpha V MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mapk11 protein Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 NCK associated protein 1 like Nck-associated protein 1 Neutrophil cytosol factor 2 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 4 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Protein-tyrosine kinase 2-beta Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Rho-associated protein kinase 1 Rho-associated protein kinase 2 SH2 domain containing 2A SH2 domain containing adaptor protein B SHC-transforming protein 2 Serine/threonine-protein kinase PAK 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Vascular endothelial growth factor A Vascular endothelial growth factor receptor 2 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Wiskott-Aldrich syndrome protein family member Wiskott-Aldrich syndrome protein family member cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta receptor protein-tyrosine kinase	A0A0G2K344 A0A8I5ZLD3 A0A8I5ZNF3 A0A8I5ZPB5 A0A8I6AH32 A0A8I6AHL8 A7E3N2 B2RZ33 D3ZN31 D3ZUP5 D3ZY46 D3ZYG0 D4A3M8 D4A3U7 D4A8H8 E9PSY0 F1LZX9 F1M707 G3V982 M0R7F3 O08775 O35346 O70142 P16612 P27791 P42930 P54100 P55161 P61589 P68182 P70600 P70618 P82995 Q5BJU7 Q5FWU0 Q5I0Q2 Q62737 Q62844 Q62868 Q63538 Q63644 Q63767 Q63768 Q63787 Q63788 Q64303 Q66H76 Q66H84 Q6GMN2 Q6RUV5 Q80ZF4 Q8CFN2 Q8R2H2 Q9ERL1 Q9QZM5 Q9WTY9 Q9WUD9 Q9Z1L0	Abi1 Abi2 Arha Arha2 Axl Baiap2 Bcar1 Brk1 Cas Cdc42 Crk Crkas Crko Csbp1 Csbp2 Cyba Cybb Cyfip1 Cyfip2 Elmo1 Elmo2 Fak Fak1 Fak2 Flk1 Fyn Hem2 Hsp27 Hsp86 Hsp90aa1 Hspb1 Hspca Itgav Itgb3 Kdr Mapk11 Mapk12 Mapk13 Mapk14 Mapkapk2 Mapkapk3 Nap1 Ncf1 Ncf2 Ncf4 Nck1 Nck2 Nckap1 Nckap1l Pak2 Pik3ca Pik3cb Pik3r1 Pik3r2 Pkacb Prkaca Prkacb Ptk2 Ptk2b Pxn Pyk2 Rac Rac1 Rhoa Rock1 Rock2 Sapk3 Sck Sh2d2a Shb Shc2 Src Vav Vav1 Vav2 Vav3 Vegf Vegfa Wasf1 Wasf2 Wasf3 Wave1
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2-associated binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2K344 A0A8I5Y949 D3ZAL7 D3ZFJ0 D4A4I3 F1MAL5 P29676 Q07014 Q07303 Q62689 Q63787 Q9Z1L0	Epo Epor Gab1 Irs2 Jak2 Lyn Pik3ca Pik3cb Pik3cd Pik3cg Pik3r1 Pik3r5

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